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Aliases for OR13C4 Gene

Aliases for OR13C4 Gene

  • Olfactory Receptor, Family 13, Subfamily C, Member 4 2 3
  • Olfactory Receptor OR9-7 3 4
  • Olfactory Receptor, Family 2, Subfamily K, Member 1 3
  • Olfactory Receptor 13C4 3
  • HSHTPCRX17 3
  • HTPCRX17 3
  • OR2K1 3
  • OR37F 3
  • OR9-7 3

External Ids for OR13C4 Gene

Previous GeneCards Identifiers for OR13C4 Gene

  • GC09U990154
  • GC09M102669
  • GC09M104368
  • GC09M106329
  • GC09M107288

Summaries for OR13C4 Gene

Entrez Gene Summary for OR13C4 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR13C4 Gene

OR13C4 (Olfactory Receptor, Family 13, Subfamily C, Member 4) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR13C7.

UniProtKB/Swiss-Prot for OR13C4 Gene

  • Odorant receptor.

Gene Wiki entry for OR13C4 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR13C4 Gene

Genomics for OR13C4 Gene

Regulatory Elements for OR13C4 Gene

Genomic Location for OR13C4 Gene

Start:
104,526,253 bp from pter
End:
104,527,209 bp from pter
Size:
957 bases
Orientation:
Minus strand

Genomic View for OR13C4 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR13C4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR13C4 Gene

Proteins for OR13C4 Gene

  • Protein details for OR13C4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGS5-O13C4_HUMAN
    Recommended name:
    Olfactory receptor 13C4
    Protein Accession:
    Q8NGS5
    Secondary Accessions:
    • Q6IF51
    • Q96R41

    Protein attributes for OR13C4 Gene

    Size:
    318 amino acids
    Molecular mass:
    35576 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR13C4 Gene

Proteomics data for OR13C4 Gene at MOPED

Post-translational modifications for OR13C4 Gene

  • Glycosylation at Asn5
  • Modification sites at PhosphoSitePlus

Other Protein References for OR13C4 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR13C4 Gene

Domains for OR13C4 Gene

Gene Families for OR13C4 Gene

HGNC:
  • OR13 :GPCR / Class A : Olfactory receptors

Protein Domains for OR13C4 Gene

Suggested Antigen Peptide Sequences for OR13C4 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NGS5

UniProtKB/Swiss-Prot:

O13C4_HUMAN :
  • Q8NGS5
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR13C4: view

Function for OR13C4 Gene

Molecular function for OR13C4 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR13C4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR13C4: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR13C4

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR13C4 Gene

Localization for OR13C4 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR13C4 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR13C4 Gene COMPARTMENTS Subcellular localization image for OR13C4 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR13C4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR13C4: view

Pathways for OR13C4 Gene

genes like me logo Genes that share pathways with OR13C4: view

Pathways by source for OR13C4 Gene

Interacting Proteins for OR13C4 Gene

Gene Ontology (GO) - Biological Process for OR13C4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
GO:1903955 positive regulation of protein targeting to mitochondrion IMP 24270810
genes like me logo Genes that share ontologies with OR13C4: view

Transcripts for OR13C4 Gene

mRNA/cDNA for OR13C4 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR13C4

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for OR13C4
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR13C4 Gene

No ASD Table

Relevant External Links for OR13C4 Gene

GeneLoc Exon Structure for
OR13C4
ECgene alternative splicing isoforms for
OR13C4

Expression for OR13C4 Gene

mRNA expression in normal human tissues for OR13C4 Gene

SOURCE GeneReport for Unigene cluster for OR13C4 Gene Hs.553601

genes like me logo Genes that share expressions with OR13C4: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for OR13C4 Gene

Orthologs for OR13C4 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR13C4 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia -- 36
  • 65 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia OR13C4 36
  • 89 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Olfr273 16
oppossum
(Monodelphis domestica)
Mammalia OPOR63 36
  • 79 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Olr845 35
  • 80.49 (n)
  • 80.06 (a)
Species with no ortholog for OR13C4:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR13C4 Gene

ENSEMBL:
Gene Tree for OR13C4 (if available)
TreeFam:
Gene Tree for OR13C4 (if available)

Paralogs for OR13C4 Gene

Selected SIMAP similar genes for OR13C4 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR13C4: view

Variants for OR13C4 Gene

Sequence variations from dbSNP and Humsavar for OR13C4 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs1403810 -- 104,528,170(-) TGCGA(A/G)AACAA upstream-variant-2KB
rs1581480 -- 104,526,046(-) AATAA(A/G)TTTCA downstream-variant-500B
rs1818874 -- 104,525,921(-) cctag(C/G)catgt downstream-variant-500B
rs5899599 -- 104,529,059(+) GGAAG(-/A)AAAAA upstream-variant-2KB
rs10820664 -- 104,527,834(+) TTACT(A/G)TTTTG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR13C4 Gene

Variant ID Type Subtype PubMed ID
nsv893670 CNV Loss 21882294
nsv466462 CNV Loss 19166990
nsv831677 CNV Gain 17160897

Relevant External Links for OR13C4 Gene

HapMap Linkage Disequilibrium report
OR13C4

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR13C4 Gene

Disorders for OR13C4 Gene

Relevant External Links for OR13C4

Genetic Association Database (GAD)
OR13C4
genes like me logo Genes that share disorders with OR13C4: view

No data available for UniProtKB/Swiss-Prot for OR13C4 Gene

Publications for OR13C4 Gene

  1. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  3. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 3 4
  4. High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy. (PMID: 24270810) Hasson S.A. … Youle R.J. (Nature 2013) 3
  5. Organization and evolutionary relatedness of OR37 olfactory receptor genes in mouse and human. (PMID: 12906860) Hoppe R. … Strotmann J. (Genomics 2003) 3

Products for OR13C4 Gene

  • antibodies-online proteins for OR13C4
  • antibodies-online antibodies for OR13C4
  • antibodies-online kits for OR13C4

Sources for OR13C4 Gene

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