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Aliases for OR11L1 Gene

Aliases for OR11L1 Gene

  • Olfactory Receptor, Family 11, Subfamily L, Member 1 2 3

External Ids for OR11L1 Gene

Previous GeneCards Identifiers for OR11L1 Gene

  • GC01U990419
  • GC01M244305
  • GC01M246070
  • GC01M248004

Summaries for OR11L1 Gene

Entrez Gene Summary for OR11L1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR11L1 Gene

OR11L1 (Olfactory Receptor, Family 11, Subfamily L, Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR6B3.

UniProtKB/Swiss-Prot for OR11L1 Gene

  • Odorant receptor.

Gene Wiki entry for OR11L1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR11L1 Gene

Genomics for OR11L1 Gene

Regulatory Elements for OR11L1 Gene

Genomic Location for OR11L1 Gene

247,840,928 bp from pter
247,841,896 bp from pter
969 bases
Minus strand

Genomic View for OR11L1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR11L1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR11L1 Gene

Proteins for OR11L1 Gene

  • Protein details for OR11L1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 11L1
    Protein Accession:
    Secondary Accessions:

    Protein attributes for OR11L1 Gene

    322 amino acids
    Molecular mass:
    36763 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR11L1 Gene

Proteomics data for OR11L1 Gene at MOPED

Post-translational modifications for OR11L1 Gene

Other Protein References for OR11L1 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

Antibody Products

No data available for DME Specific Peptides for OR11L1 Gene

Domains for OR11L1 Gene

Gene Families for OR11L1 Gene

  • OR11 :GPCR / Class A : Olfactory receptors

Protein Domains for OR11L1 Gene

Suggested Antigen Peptide Sequences for OR11L1 Gene

Graphical View of Domain Structure for InterPro Entry



  • Q8NGX0
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR11L1: view

Function for OR11L1 Gene

Molecular function for OR11L1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR11L1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0004930 G-protein coupled receptor activity IBA --
GO:0004984 olfactory receptor activity IBA --
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR11L1: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR11L1

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR11L1 Gene

Localization for OR11L1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR11L1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR11L1 Gene COMPARTMENTS Subcellular localization image for OR11L1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR11L1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane IBA --
GO:0016021 integral component of membrane --
GO:0070062 extracellular exosome IDA 19056867
genes like me logo Genes that share ontologies with OR11L1: view

Pathways for OR11L1 Gene

genes like me logo Genes that share pathways with OR11L1: view

Pathways by source for OR11L1 Gene

Interacting Proteins for OR11L1 Gene

Gene Ontology (GO) - Biological Process for OR11L1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA --
GO:0008150 biological_process ND --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR11L1: view

Transcripts for OR11L1 Gene

mRNA/cDNA for OR11L1 Gene

(1) Selected AceView cDNA sequences:
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR11L1

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR11L1 Gene

No ASD Table

Relevant External Links for OR11L1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR11L1 Gene

mRNA expression in normal human tissues for OR11L1 Gene

SOURCE GeneReport for Unigene cluster for OR11L1 Gene Hs.553781

genes like me logo Genes that share expressions with OR11L1: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for OR11L1 Gene

Orthologs for OR11L1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR11L1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia OR11L1 35
  • 82.53 (n)
  • 81.03 (a)
OR11L1 36
  • 78 (a)
(Mus musculus)
Mammalia Olfr323 35
  • 78.46 (n)
  • 79.42 (a)
Olfr323 16
Olfr323 36
  • 77 (a)
(Rattus norvegicus)
Mammalia Olr1432 35
  • 77.5 (n)
  • 76.34 (a)
(Canis familiaris)
Mammalia OR11L1 36
  • 77 (a)
(Monodelphis domestica)
Mammalia OR11L1 36
  • 72 (a)
(Anolis carolinensis)
Reptilia OR11L1 36
  • 62 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100488665 35
  • 58.09 (n)
  • 55.45 (a)
(Danio rerio)
Actinopterygii or103-5 36
  • 26 (a)
Species with no ortholog for OR11L1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for OR11L1 Gene

Gene Tree for OR11L1 (if available)
Gene Tree for OR11L1 (if available)

Paralogs for OR11L1 Gene

Paralogs for OR11L1 Gene

Selected SIMAP similar genes for OR11L1 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with OR11L1: view

Variants for OR11L1 Gene

Sequence variations from dbSNP and Humsavar for OR11L1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
VAR_034305 -
VAR_053295 -
VAR_053296 -
VAR_053297 -

Structural Variations from Database of Genomic Variants (DGV) for OR11L1 Gene

Variant ID Type Subtype PubMed ID
esv33129 CNV Gain+Loss 17666407
nsv873440 CNV Gain 21882294
dgv204e1 CNV Complex 17122850
esv34503 CNV Gain 17911159
nsv515858 CNV Gain+Loss 19592680
nsv873442 CNV Gain 21882294
dgv205e1 CNV Complex 17122850
nsv873443 CNV Gain 21882294

Relevant External Links for OR11L1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR11L1 Gene

Disorders for OR11L1 Gene

No disorders were found for OR11L1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for OR11L1 Gene

Publications for OR11L1 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3
  3. Large-scale proteomics and phosphoproteomics of urinary exosomes. (PMID: 19056867) Gonzales P.A. … Knepper M.A. (J. Am. Soc. Nephrol. 2009) 3

Products for OR11L1 Gene

Sources for OR11L1 Gene

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