Free for academic non-profit institutions. Other users need a Commercial license

Aliases for OR11H2 Gene

Aliases for OR11H2 Gene

  • Olfactory Receptor, Family 11, Subfamily H, Member 2 2 3
  • Olfactory Receptor OR14-1 3 4
  • C14orf15 3 4
  • OR11H2P 3 4
  • Olfactory Receptor, Family 11, Subfamily H, Member 8 Pseudogene 2
  • Seven Transmembrane Helix Receptor 3
  • Olfactory Receptor 11H2 3
  • OR11H8P 3

External Ids for OR11H2 Gene

Previous Symbols for OR11H2 Gene

  • OR11H2P
  • OR11H8P
  • C14orf15

Summaries for OR11H2 Gene

Entrez Gene Summary for OR11H2 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR11H2 Gene

OR11H2 (Olfactory Receptor, Family 11, Subfamily H, Member 2) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR11H1.

UniProtKB/Swiss-Prot for OR11H2 Gene

  • Odorant receptor.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR11H2 Gene

Genomics for OR11H2 Gene

Genomic Location for OR11H2 Gene

Start:
19,712,904 bp from pter
End:
19,714,332 bp from pter
Size:
1,429 bases
Orientation:
Minus strand

Genomic View for OR11H2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR11H2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR11H2 Gene

No data available for Regulatory Elements for OR11H2 Gene

Proteins for OR11H2 Gene

  • Protein details for OR11H2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NH07-O11H2_HUMAN
    Recommended name:
    Olfactory receptor 11H2
    Protein Accession:
    Q8NH07
    Secondary Accessions:

    Protein attributes for OR11H2 Gene

    Size:
    326 amino acids
    Molecular mass:
    36531 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR11H2 Gene

Proteomics data for OR11H2 Gene at MOPED

Post-translational modifications for OR11H2 Gene

  • Glycosylation at Asn13, Asn18, and Asn106

Other Protein References for OR11H2 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR11H2 Gene

Domains for OR11H2 Gene

Gene Families for OR11H2 Gene

HGNC:
  • OR11 :GPCR / Class A : Olfactory receptors

Protein Domains for OR11H2 Gene

Suggested Antigen Peptide Sequences for OR11H2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NH07

UniProtKB/Swiss-Prot:

O11H2_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q8NH07
genes like me logo Genes that share domains with OR11H2: view

Function for OR11H2 Gene

Molecular function for OR11H2 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR11H2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR11H2: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR11H2 Gene

Localization for OR11H2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR11H2 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR11H2 Gene COMPARTMENTS Subcellular localization image for OR11H2 gene
Compartment Confidence
plasma membrane 5
peroxisome 1

Gene Ontology (GO) - Cellular Components for OR11H2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR11H2: view

Pathways for OR11H2 Gene

genes like me logo Genes that share pathways with OR11H2: view

Pathways by source for OR11H2 Gene

Interacting Proteins for OR11H2 Gene

Gene Ontology (GO) - Biological Process for OR11H2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR11H2: view

Transcripts for OR11H2 Gene

mRNA/cDNA for OR11H2 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR11H2 Gene

No ASD Table

Relevant External Links for OR11H2 Gene

GeneLoc Exon Structure for
OR11H2
ECgene alternative splicing isoforms for
OR11H2

Expression for OR11H2 Gene

mRNA expression in normal human tissues for OR11H2 Gene

genes like me logo Genes that share expressions with OR11H2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for OR11H2 Gene

Orthologs for OR11H2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR11H2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC740929 35
  • 98.47 (n)
  • 96.01 (a)
cow
(Bos Taurus)
Mammalia LOC784332 35
  • 86.4 (n)
  • 81.93 (a)
dog
(Canis familiaris)
Mammalia LOC102153096 35
  • 87.9 (n)
  • 84.68 (a)
Species with no ortholog for OR11H2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR11H2 Gene

ENSEMBL:
Gene Tree for OR11H2 (if available)
TreeFam:
Gene Tree for OR11H2 (if available)

Paralogs for OR11H2 Gene

Paralogs for OR11H2 Gene

Selected SIMAP similar genes for OR11H2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR11H2: view

Variants for OR11H2 Gene

Sequence variations from dbSNP and Humsavar for OR11H2 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
rs1590546 -- 19,713,189(+) AAGGC(A/G)TACCC missense, reference
rs1830970 -- 19,713,480(+) GATAG(A/T)GCAAG missense, reference
rs3000029 -- 19,713,375(+) AGGGC(A/T)TCTGA reference, missense
rs11486342 -- 19,715,816(+) CAAAA(C/G)TTTTG upstream-variant-2KB
rs11625510 -- 19,713,214(+) GACAA(G/T)AGTAT missense, reference

Structural Variations from Database of Genomic Variants (DGV) for OR11H2 Gene

Variant ID Type Subtype PubMed ID
esv23873 CNV Gain+Loss 19812545
esv33527 CNV Gain+Loss 17666407
nsv819711 CNV Loss 19587683
nsv9117 CNV Gain+Loss 18304495
dgv45e180 CNV Loss 20482838
nsv901117 CNV Gain 21882294
dgv599e1 CNV Complex 17122850
nsv428292 CNV Gain+Loss 18775914
nsv433422 CNV Gain 18776910
dgv1811n71 CNV Gain 21882294
esv2748433 CNV Deletion 23290073
nsv436829 CNV Insertion 17901297
dgv1812n71 CNV Gain 21882294
dgv601e1 CNV Complex 17122850
dgv1813n71 CNV Gain 21882294
dgv1814n71 CNV Gain 21882294
nsv901139 CNV Loss 21882294
dgv1816n71 CNV Gain 21882294
dgv1819n71 CNV Gain 21882294
dgv6n31 CNV Duplication 19718026
dgv1823n71 CNV Gain 21882294
nsv901168 CNV Gain+Loss 21882294
dgv1824n71 CNV Gain 21882294
dgv24n68 CNV Gain 17160897
nsv901192 CNV Loss 21882294
nsv901198 CNV Loss 21882294
nsv901202 CNV Gain 21882294
nsv901215 CNV Gain 21882294
dgv1825n71 CNV Gain 21882294
dgv1826n71 CNV Gain 21882294
dgv602e1 CNV Complex 17122850
dgv603e1 CNV Complex 17122850
dgv1827n71 CNV Gain+Loss 21882294
dgv1828n71 CNV Gain 21882294
dgv1829n71 CNV Gain 21882294
dgv1830n71 CNV Gain 21882294
dgv1831n71 CNV Gain+Loss 21882294
dgv1832n71 CNV Gain 21882294
dgv1833n71 CNV Loss 21882294
dgv1834n71 CNV Gain 21882294

Relevant External Links for OR11H2 Gene

HapMap Linkage Disequilibrium report
OR11H2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR11H2 Gene

Disorders for OR11H2 Gene

No disorders were found for OR11H2 Gene.

No data available for UniProtKB/Swiss-Prot for OR11H2 Gene

Publications for OR11H2 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4

Products for OR11H2 Gene

Sources for OR11H2 Gene

Back to Top

Content