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Aliases for OR11H2 Gene

Aliases for OR11H2 Gene

  • Olfactory Receptor Family 11 Subfamily H Member 2 2 3 5
  • Olfactory Receptor OR14-1 3 4
  • C14orf15 3 4
  • OR11H2P 3 4
  • Olfactory Receptor, Family 11, Subfamily H, Member 8 Pseudogene 2
  • Olfactory Receptor, Family 11, Subfamily H, Member 2 2
  • Seven Transmembrane Helix Receptor 3
  • Olfactory Receptor 11H2 3
  • OR11H13 3
  • OR11H8P 3

External Ids for OR11H2 Gene

Previous HGNC Symbols for OR11H2 Gene

  • OR11H2P
  • OR11H8P
  • C14orf15

Previous GeneCards Identifiers for OR11H2 Gene

  • GC13U900259
  • GC14M019252
  • GC14M020180

Summaries for OR11H2 Gene

Entrez Gene Summary for OR11H2 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR11H2 Gene

OR11H2 (Olfactory Receptor Family 11 Subfamily H Member 2) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR11H1.

UniProtKB/Swiss-Prot for OR11H2 Gene

  • Odorant receptor.

No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR11H2 Gene

Genomics for OR11H2 Gene

Genomic Location for OR11H2 Gene

Chromosome:
14
Start:
19,712,904 bp from pter
End:
19,714,332 bp from pter
Size:
1,429 bases
Orientation:
Minus strand

Genomic View for OR11H2 Gene

Genes around OR11H2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR11H2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR11H2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR11H2 Gene

No data available for Regulatory Elements for OR11H2 Gene

Proteins for OR11H2 Gene

  • Protein details for OR11H2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NH07-O11H2_HUMAN
    Recommended name:
    Olfactory receptor 11H2
    Protein Accession:
    Q8NH07

    Protein attributes for OR11H2 Gene

    Size:
    326 amino acids
    Molecular mass:
    36531 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR11H2 Gene

Post-translational modifications for OR11H2 Gene

  • Glycosylation at Asn13, Asn18, and posLast=106106

Other Protein References for OR11H2 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR11H2 Gene

Domains & Families for OR11H2 Gene

Gene Families for OR11H2 Gene

Protein Domains for OR11H2 Gene

Suggested Antigen Peptide Sequences for OR11H2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NH07

UniProtKB/Swiss-Prot:

O11H2_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR11H2: view

Function for OR11H2 Gene

Molecular function for OR11H2 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR11H2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR11H2: view

Animal Model Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR11H2 Gene

Localization for OR11H2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR11H2 Gene

Cell membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for OR11H2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR11H2: view

No data available for Subcellular locations from COMPARTMENTS for OR11H2 Gene

Pathways & Interactions for OR11H2 Gene

genes like me logo Genes that share pathways with OR11H2: view

Pathways by source for OR11H2 Gene

Interacting Proteins for OR11H2 Gene

Gene Ontology (GO) - Biological Process for OR11H2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0007608 sensory perception of smell IEA --
GO:0050896 response to stimulus IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR11H2: view

No data available for SIGNOR curated interactions for OR11H2 Gene

Drugs & Compounds for OR11H2 Gene

No Compound Related Data Available

Transcripts for OR11H2 Gene

mRNA/cDNA for OR11H2 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR11H2 Gene

No ASD Table

Relevant External Links for OR11H2 Gene

GeneLoc Exon Structure for
OR11H2
ECgene alternative splicing isoforms for
OR11H2

Expression for OR11H2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OR11H2 Gene

NURSA nuclear receptor signaling pathways regulating expression of OR11H2 Gene:

OR11H2
genes like me logo Genes that share expression patterns with OR11H2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR11H2 Gene

Orthologs for OR11H2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR11H2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC740929 34
  • 98.47 (n)
dog
(Canis familiaris)
Mammalia LOC102153096 34
  • 87.9 (n)
cow
(Bos Taurus)
Mammalia LOC784332 34
  • 86.4 (n)
Species where no ortholog for OR11H2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR11H2 Gene

ENSEMBL:
Gene Tree for OR11H2 (if available)
TreeFam:
Gene Tree for OR11H2 (if available)

Paralogs for OR11H2 Gene

(450) SIMAP similar genes for OR11H2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR11H2: view

Variants for OR11H2 Gene

Sequence variations from dbSNP and Humsavar for OR11H2 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs1000271733 -- 19,712,918(+) ATGGA(A/G)GAATA utr-variant-3-prime
rs1004415096 -- 19,715,009(+) TTTAC(A/T)TTTGA upstream-variant-2KB
rs1004446353 -- 19,715,312(+) TTTTC(A/G)TATGA upstream-variant-2KB
rs1014271879 -- 19,712,485(+) TATGT(A/G)TTAGT downstream-variant-500B
rs1015254456 -- 19,715,052(+) CTTAT(A/C)TGCTT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR11H2 Gene

Variant ID Type Subtype PubMed ID
dgv1050n106 CNV duplication 24896259
dgv14e213 CNV gain 24956385
dgv1753n100 CNV gain 25217958
dgv1757n100 CNV gain 25217958
dgv1759n100 CNV gain 25217958
dgv1761n100 CNV gain+loss 25217958
dgv1762n100 CNV loss 25217958
dgv1764n100 CNV loss 25217958
dgv1765n100 CNV gain+loss 25217958
dgv1766n100 CNV gain 25217958
dgv1767n100 CNV loss 25217958
dgv1768n100 CNV gain 25217958
dgv1769n100 CNV gain 25217958
dgv1770n100 CNV gain+loss 25217958
dgv1771n100 CNV loss 25217958
dgv1772n100 CNV gain 25217958
dgv1773n100 CNV gain+loss 25217958
dgv1774n100 CNV gain 25217958
dgv1775n100 CNV gain 25217958
dgv24n68 CNV gain 17160897
dgv33e203 CNV gain+loss 21179565
dgv3489n54 CNV gain 21841781
dgv3494n54 CNV loss 21841781
dgv3513n54 CNV loss 21841781
dgv3518n54 CNV gain 21841781
dgv3519n54 CNV gain 21841781
dgv3520n54 CNV gain 21841781
dgv45e180 CNV loss 20482838
dgv6n31 CNV gain 19718026
dgv86n111 CNV duplication 26073780
dgv87n111 CNV duplication 26073780
esv23873 CNV gain+loss 19812545
esv2748433 CNV deletion 23290073
esv2759971 CNV gain+loss 17122850
esv33527 CNV gain+loss 17666407
esv3584743 CNV gain 24956385
esv3584754 CNV gain 24956385
esv3892451 CNV gain 25118596
esv3892461 CNV gain 25118596
esv3892464 CNV gain 25118596
nsv1038826 CNV gain 25217958
nsv1044659 CNV gain 25217958
nsv1047431 CNV loss 25217958
nsv1048393 CNV gain+loss 25217958
nsv1139600 CNV duplication 24896259
nsv1150747 CNV duplication 26484159
nsv1160152 CNV duplication 26073780
nsv1160154 CNV duplication 26073780
nsv1160157 CNV duplication 26073780
nsv428292 CNV gain+loss 18775914
nsv433422 CNV gain 18776910
nsv436829 CNV insertion 17901297
nsv563705 CNV loss 21841781
nsv563739 CNV loss 21841781
nsv563742 CNV gain 21841781
nsv819711 CNV loss 19587683
nsv9117 CNV gain+loss 18304495
nsv952808 CNV duplication 24416366
nsv977538 CNV duplication 23825009
nsv977539 CNV duplication 23825009

Relevant External Links for OR11H2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OR11H2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for OR11H2 Gene

Disorders for OR11H2 Gene

Relevant External Links for OR11H2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OR11H2

No disorders were found for OR11H2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR11H2 Gene

Publications for OR11H2 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 64

Products for OR11H2 Gene

Sources for OR11H2 Gene

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