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Aliases for OR11H12 Gene

Aliases for OR11H12 Gene

  • Olfactory Receptor, Family 11, Subfamily H, Member 12 2 3

External Ids for OR11H12 Gene

Previous GeneCards Identifiers for OR11H12 Gene

  • GC14P018436
  • GC14P019380

Summaries for OR11H12 Gene

Entrez Gene Summary for OR11H12 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR11H12 Gene

OR11H12 (Olfactory Receptor, Family 11, Subfamily H, Member 12) is a Protein Coding gene. Among its related pathways are Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR6N1.

UniProtKB/Swiss-Prot for OR11H12 Gene

  • Odorant receptor.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR11H12 Gene

Genomics for OR11H12 Gene

Regulatory Elements for OR11H12 Gene

Genomic Location for OR11H12 Gene

18,601,045 bp from pter
18,602,129 bp from pter
1,085 bases
Plus strand

Genomic View for OR11H12 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR11H12 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR11H12 Gene

Proteins for OR11H12 Gene

  • Protein details for OR11H12 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 11H12
    Protein Accession:

    Protein attributes for OR11H12 Gene

    326 amino acids
    Molecular mass:
    36530 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR11H12 Gene

Proteomics data for OR11H12 Gene at MOPED

Post-translational modifications for OR11H12 Gene

  • Glycosylation at Asn 13, Asn 18, and Asn 106

Other Protein References for OR11H12 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR11H12 Gene

Domains & Families for OR11H12 Gene

Gene Families for OR11H12 Gene

Protein Domains for OR11H12 Gene

Suggested Antigen Peptide Sequences for OR11H12 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR11H12: view

Function for OR11H12 Gene

Molecular function for OR11H12 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR11H12 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IBA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR11H12: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR11H12

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR11H12 Gene

Localization for OR11H12 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR11H12 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR11H12 Gene COMPARTMENTS Subcellular localization image for OR11H12 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR11H12 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005887 integral component of plasma membrane IBA --
GO:0016021 integral component of membrane --
genes like me logo Genes that share ontologies with OR11H12: view

Pathways & Interactions for OR11H12 Gene

SuperPathways for OR11H12 Gene

Superpath Contained pathways
1 Olfactory Signaling Pathway
genes like me logo Genes that share pathways with OR11H12: view

Pathways by source for OR11H12 Gene

1 KEGG pathway for OR11H12 Gene

Interacting Proteins for OR11H12 Gene

STRING Interaction Network Preview (showing 3 interactants - click image to see details)
Selected Interacting proteins: ENSP00000449002 for OR11H12 Gene via STRING

Gene Ontology (GO) - Biological Process for OR11H12 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007166 cell surface receptor signaling pathway IBA --
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR11H12: view

No data available for SIGNOR curated interactions for OR11H12 Gene

Drugs & Compounds for OR11H12 Gene

No Compound Related Data Available

Transcripts for OR11H12 Gene

mRNA/cDNA for OR11H12 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR11H12

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR11H12 Gene

No ASD Table

Relevant External Links for OR11H12 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR11H12 Gene

mRNA expression in normal human tissues for OR11H12 Gene

SOURCE GeneReport for Unigene cluster for OR11H12 Gene Hs.534880

genes like me logo Genes that share expression patterns with OR11H12: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for OR11H12 Gene

Orthologs for OR11H12 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR11H12 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia LOC784332 35
  • 86.29 (n)
  • 81.93 (a)
-- 36
  • 82 (a)
-- 36
  • 78 (a)
(Canis familiaris)
Mammalia LOC102153096 35
  • 87.9 (n)
  • 85.08 (a)
-- 36
  • 62 (a)
(Pan troglodytes)
Mammalia LOC740929 35
  • 98.57 (n)
  • 96.63 (a)
-- 36
  • 97 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 60 (a)
(Mus musculus)
Mammalia Olfr736 36
  • 63 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 59 (a)
Species with no ortholog for OR11H12:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR11H12 Gene

Gene Tree for OR11H12 (if available)
Gene Tree for OR11H12 (if available)

Paralogs for OR11H12 Gene

Paralogs for OR11H12 Gene

(454) SIMAP similar genes for OR11H12 Gene using alignment to 1 proteins: Pseudogenes for OR11H12 Gene

genes like me logo Genes that share paralogs with OR11H12: view

Variants for OR11H12 Gene

Structural Variations from Database of Genomic Variants (DGV) for OR11H12 Gene

Variant ID Type Subtype PubMed ID
esv23873 CNV Gain+Loss 19812545
esv33527 CNV Gain+Loss 17666407
nsv819711 CNV Loss 19587683
nsv9117 CNV Gain+Loss 18304495

Variation tolerance for OR11H12 Gene

Gene Damage Index Score: 13.26; 95.28% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR11H12 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for OR11H12 Gene

Disorders for OR11H12 Gene

Relevant External Links for OR11H12

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with OR11H12: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR11H12 Gene

Publications for OR11H12 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 67

Products for OR11H12 Gene

Sources for OR11H12 Gene

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