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Aliases for OR11H1 Gene

Aliases for OR11H1 Gene

  • Olfactory Receptor Family 11 Subfamily H Member 1 2 3 5
  • Olfactory Receptor, Family 11, Subfamily H, Member 1 2 3
  • Olfactory Receptor OR22-1 3 4
  • Seven Transmembrane Helix Receptor 3
  • OR11H12 3
  • OR22-1 3

External Ids for OR11H1 Gene

Previous GeneCards Identifiers for OR11H1 Gene

  • GC22U990212
  • GC14M019250
  • GC22M014824
  • GC22M016448

Summaries for OR11H1 Gene

Entrez Gene Summary for OR11H1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR11H1 Gene

OR11H1 (Olfactory Receptor Family 11 Subfamily H Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR11G2.

UniProtKB/Swiss-Prot for OR11H1 Gene

  • Odorant receptor.

Gene Wiki entry for OR11H1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR11H1 Gene

Genomics for OR11H1 Gene

Regulatory Elements for OR11H1 Gene

Enhancers for OR11H1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around OR11H1 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR11H1 Gene

15,528,158 bp from pter
15,529,139 bp from pter
982 bases
Plus strand

Genomic View for OR11H1 Gene

Genes around OR11H1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR11H1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR11H1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR11H1 Gene

Proteins for OR11H1 Gene

  • Protein details for OR11H1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 11H1
    Protein Accession:
    Secondary Accessions:
    • Q6IEX0
    • Q96R32

    Protein attributes for OR11H1 Gene

    326 amino acids
    Molecular mass:
    36578 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR11H1 Gene

Proteomics data for OR11H1 Gene at MOPED

Post-translational modifications for OR11H1 Gene

  • Glycosylation at Asn 13, Asn 18, and Asn 106

Other Protein References for OR11H1 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR11H1 Gene

Domains & Families for OR11H1 Gene

Gene Families for OR11H1 Gene

Protein Domains for OR11H1 Gene

Suggested Antigen Peptide Sequences for OR11H1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR11H1: view

Function for OR11H1 Gene

Molecular function for OR11H1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR11H1 Gene

Localization for OR11H1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR11H1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR11H1 Gene COMPARTMENTS Subcellular localization image for OR11H1 gene
Compartment Confidence
plasma membrane 5
peroxisome 1

Gene Ontology (GO) - Cellular Components for OR11H1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005887 integral component of plasma membrane IBA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR11H1: view

Pathways & Interactions for OR11H1 Gene

genes like me logo Genes that share pathways with OR11H1: view

Pathways by source for OR11H1 Gene

Interacting Proteins for OR11H1 Gene

Gene Ontology (GO) - Biological Process for OR11H1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR11H1: view

No data available for SIGNOR curated interactions for OR11H1 Gene

Drugs & Compounds for OR11H1 Gene

No Compound Related Data Available

Transcripts for OR11H1 Gene

mRNA/cDNA for OR11H1 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR11H1 Gene

No ASD Table

Relevant External Links for OR11H1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR11H1 Gene

mRNA expression in normal human tissues for OR11H1 Gene

SOURCE GeneReport for Unigene cluster for OR11H1 Gene Hs.554706

genes like me logo Genes that share expression patterns with OR11H1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for OR11H1 Gene

Orthologs for OR11H1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR11H1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia LOC784332 35
  • 86.4 (n)
  • 81.62 (a)
-- 36
  • 82 (a)
-- 36
  • 78 (a)
(Canis familiaris)
Mammalia LOC102153096 35
  • 87.9 (n)
  • 84.68 (a)
-- 36
  • 64 (a)
(Pan troglodytes)
Mammalia LOC740929 35
  • 98.67 (n)
  • 96.63 (a)
-- 36
  • 97 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 62 (a)
(Mus musculus)
Mammalia Olfr739 36
  • 61 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 58 (a)
Species with no ortholog for OR11H1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR11H1 Gene

Gene Tree for OR11H1 (if available)
Gene Tree for OR11H1 (if available)

Paralogs for OR11H1 Gene

(450) SIMAP similar genes for OR11H1 Gene using alignment to 1 proteins: Pseudogenes for OR11H1 Gene

genes like me logo Genes that share paralogs with OR11H1: view

Variants for OR11H1 Gene

Structural Variations from Database of Genomic Variants (DGV) for OR11H1 Gene

Variant ID Type Subtype PubMed ID
esv25550 CNV Gain+Loss 19812545
nsv821525 CNV Duplication 20802225
nsv9866 CNV Gain+Loss 18304495
dgv172e55 CNV Gain 17911159
dgv1376e1 CNV Complex 17122850
esv995567 CNV Loss 20482838
esv33426 CNV Gain+Loss 17666407
nsv511070 OTHER Inversion 20534489
nsv834116 CNV Gain 17160897
nsv469638 CNV Complex 16826518
nsv471593 CNV Gain+Loss 15918152
nsv471422 CNV Duplication 19718026
nsv514958 CNV Complex 21397061

Variation tolerance for OR11H1 Gene

Gene Damage Index Score: 8.84; 86.94% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Relevant External Links for OR11H1 Gene

Disorders for OR11H1 Gene

Relevant External Links for OR11H1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for OR11H1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR11H1 Gene

Publications for OR11H1 Gene

  1. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 2 3 4 67
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3

Products for OR11H1 Gene

Sources for OR11H1 Gene