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Aliases for OR11H1 Gene

Aliases for OR11H1 Gene

  • Olfactory Receptor, Family 11, Subfamily H, Member 1 2 3
  • Olfactory Receptor OR22-1 3 4
  • Seven Transmembrane Helix Receptor 3
  • Olfactory Receptor 11H1 3
  • OR22-1 3

External Ids for OR11H1 Gene

Summaries for OR11H1 Gene

Entrez Gene Summary for OR11H1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR11H1 Gene

OR11H1 (Olfactory Receptor, Family 11, Subfamily H, Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR6N1.

UniProtKB/Swiss-Prot for OR11H1 Gene

  • Odorant receptor.

Gene Wiki entry for OR11H1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR11H1 Gene

Genomics for OR11H1 Gene

Genomic Location for OR11H1 Gene

Start:
15,528,158 bp from pter
End:
15,529,139 bp from pter
Size:
982 bases
Orientation:
Plus strand

Genomic View for OR11H1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR11H1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR11H1 Gene

Regulatory Elements for OR11H1 Gene

Proteins for OR11H1 Gene

  • Protein details for OR11H1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NG94-O11H1_HUMAN
    Recommended name:
    Olfactory receptor 11H1
    Protein Accession:
    Q8NG94
    Secondary Accessions:
    • Q6IEX0
    • Q96R32

    Protein attributes for OR11H1 Gene

    Size:
    326 amino acids
    Molecular mass:
    36578 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR11H1 Gene

Proteomics data for OR11H1 Gene at MOPED

Post-translational modifications for OR11H1 Gene

  • Glycosylation at Asn13, Asn18, and Asn106

Other Protein References for OR11H1 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR11H1 Gene

Domains for OR11H1 Gene

Gene Families for OR11H1 Gene

HGNC:
  • OR11 :GPCR / Class A : Olfactory receptors

Protein Domains for OR11H1 Gene

Suggested Antigen Peptide Sequences for OR11H1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NG94

UniProtKB/Swiss-Prot:

O11H1_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q8NG94
genes like me logo Genes that share domains with OR11H1: view

Function for OR11H1 Gene

Molecular function for OR11H1 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR11H1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR11H1: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR11H1 Gene

Localization for OR11H1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR11H1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR11H1 Gene COMPARTMENTS Subcellular localization image for OR11H1 gene
Compartment Confidence
plasma membrane 5
peroxisome 1

Gene Ontology (GO) - Cellular Components for OR11H1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR11H1: view

Pathways for OR11H1 Gene

genes like me logo Genes that share pathways with OR11H1: view

Pathways by source for OR11H1 Gene

Interacting Proteins for OR11H1 Gene

Gene Ontology (GO) - Biological Process for OR11H1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR11H1: view

Transcripts for OR11H1 Gene

mRNA/cDNA for OR11H1 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR11H1 Gene

No ASD Table

Relevant External Links for OR11H1 Gene

GeneLoc Exon Structure for
OR11H1
ECgene alternative splicing isoforms for
OR11H1

Expression for OR11H1 Gene

mRNA expression in normal human tissues for OR11H1 Gene

SOURCE GeneReport for Unigene cluster for OR11H1 Gene Hs.554706

genes like me logo Genes that share expressions with OR11H1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for OR11H1 Gene

Orthologs for OR11H1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR11H1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 97 (a)
OneToMany
LOC740929 35
  • 98.67 (n)
  • 96.63 (a)
cow
(Bos Taurus)
Mammalia -- 36
  • 82 (a)
ManyToMany
-- 36
  • 78 (a)
ManyToMany
LOC784332 35
  • 86.4 (n)
  • 81.62 (a)
dog
(Canis familiaris)
Mammalia -- 36
  • 64 (a)
ManyToMany
LOC102153096 35
  • 87.9 (n)
  • 84.68 (a)
mouse
(Mus musculus)
Mammalia Olfr739 36
  • 61 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 62 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 58 (a)
OneToMany
Species with no ortholog for OR11H1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR11H1 Gene

ENSEMBL:
Gene Tree for OR11H1 (if available)
TreeFam:
Gene Tree for OR11H1 (if available)

Paralogs for OR11H1 Gene

Paralogs for OR11H1 Gene

Selected SIMAP similar genes for OR11H1 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for OR11H1 Gene

genes like me logo Genes that share paralogs with OR11H1: view

Variants for OR11H1 Gene

Sequence variations from dbSNP and Humsavar for OR11H1 Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type MAF
rs4983292 -- 15,529,277(-) GGGTC(A/C)AACAG downstream-variant-500B
rs9617248 -- 15,529,366(-) GTATT(C/T)CTCAG downstream-variant-500B
rs9617249 -- 15,529,064(-) ATAAG(A/G)GGATT reference, synonymous-codon
rs9617250 -- 15,527,101(-) TATGA(C/T)TAGTT upstream-variant-2KB
rs9653882 -- 15,526,209(-) GAGGA(C/T)ATCAG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR11H1 Gene

Variant ID Type Subtype PubMed ID
esv25550 CNV Gain+Loss 19812545
nsv821525 CNV Duplication 20802225
nsv9866 CNV Gain+Loss 18304495
dgv172e55 CNV Gain 17911159
dgv1376e1 CNV Complex 17122850
esv995567 CNV Loss 20482838
esv33426 CNV Gain+Loss 17666407
nsv511070 OTHER Inversion 20534489
nsv834116 CNV Gain 17160897
nsv469638 CNV Complex 16826518
nsv471593 CNV Gain+Loss 15918152
nsv471422 CNV Duplication 19718026
nsv514958 CNV Complex 21397061

Relevant External Links for OR11H1 Gene

HapMap Linkage Disequilibrium report
OR11H1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR11H1 Gene

Disorders for OR11H1 Gene

No disorders were found for OR11H1 Gene.

No data available for UniProtKB/Swiss-Prot for OR11H1 Gene

Publications for OR11H1 Gene

  1. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 2 3 4
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  3. The DNA sequence of human chromosome 22. (PMID: 10591208) Dunham I. … Wright H. (Nature 1999) 4

Products for OR11H1 Gene

Sources for OR11H1 Gene

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