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Aliases for OR11G2 Gene

Aliases for OR11G2 Gene

  • Olfactory Receptor, Family 11, Subfamily G, Member 2 2 3
  • Olfactory Receptor OR14-34 3 4
  • Olfactory Receptor 11G2 3
  • OR14-34 3

External Ids for OR11G2 Gene

Summaries for OR11G2 Gene

Entrez Gene Summary for OR11G2 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR11G2 Gene

OR11G2 (Olfactory Receptor, Family 11, Subfamily G, Member 2) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR6N1.

UniProtKB/Swiss-Prot for OR11G2 Gene

  • Odorant receptor.

Gene Wiki entry for OR11G2 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR11G2 Gene

Genomics for OR11G2 Gene

Genomic Location for OR11G2 Gene

Start:
20,197,336 bp from pter
End:
20,198,446 bp from pter
Size:
1,111 bases
Orientation:
Plus strand

Genomic View for OR11G2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR11G2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR11G2 Gene

Regulatory Elements for OR11G2 Gene

Proteins for OR11G2 Gene

  • Protein details for OR11G2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGC1-O11G2_HUMAN
    Recommended name:
    Olfactory receptor 11G2
    Protein Accession:
    Q8NGC1
    Secondary Accessions:
    • Q6IF09
    • Q96R33

    Protein attributes for OR11G2 Gene

    Size:
    345 amino acids
    Molecular mass:
    38871 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC06113.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for OR11G2 Gene

Proteomics data for OR11G2 Gene at MOPED

Post-translational modifications for OR11G2 Gene

Other Protein References for OR11G2 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR11G2 Gene

Domains for OR11G2 Gene

Gene Families for OR11G2 Gene

HGNC:
  • OR11 :GPCR / Class A : Olfactory receptors

Protein Domains for OR11G2 Gene

UniProtKB/Swiss-Prot:

O11G2_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q8NGC1
genes like me logo Genes that share domains with OR11G2: view

Function for OR11G2 Gene

Molecular function for OR11G2 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR11G2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR11G2: view

Phenotypes for OR11G2 Gene

GenomeRNAi human phenotypes for OR11G2:
genes like me logo Genes that share phenotypes with OR11G2: view

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR11G2 Gene

Localization for OR11G2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR11G2 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR11G2 Gene COMPARTMENTS Subcellular localization image for OR11G2 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR11G2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR11G2: view

Pathways for OR11G2 Gene

genes like me logo Genes that share pathways with OR11G2: view

Pathways by source for OR11G2 Gene

Interacting Proteins for OR11G2 Gene

Gene Ontology (GO) - Biological Process for OR11G2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR11G2: view

Transcripts for OR11G2 Gene

mRNA/cDNA for OR11G2 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR11G2 Gene

No ASD Table

Relevant External Links for OR11G2 Gene

GeneLoc Exon Structure for
OR11G2
ECgene alternative splicing isoforms for
OR11G2

Expression for OR11G2 Gene

mRNA expression in normal human tissues for OR11G2 Gene

SOURCE GeneReport for Unigene cluster for OR11G2 Gene Hs.554582

genes like me logo Genes that share expressions with OR11G2: view

Orthologs for OR11G2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR11G2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC473316 36
  • 98.82 (n)
  • 98.39 (a)
cow
(Bos Taurus)
Mammalia -- 37
  • 79 (a)
OneToMany
-- 37
  • 83 (a)
OneToMany
OR11G2 36
  • 87.99 (n)
  • 83.77 (a)
dog
(Canis familiaris)
Mammalia LOC482549 36
  • 86.13 (n)
  • 82.9 (a)
OR11G2 37
  • 82 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Olfr742 37
  • 74 (a)
OneToMany
Olfr744 36
  • 85.12 (n)
  • 81.76 (a)
Olfr744 16
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 70 (a)
OneToMany
-- 37
  • 65 (a)
OneToMany
-- 37
  • 77 (a)
OneToMany
-- 37
  • 75 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 62 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Olr1620 36
  • 84 (n)
  • 80.33 (a)
Species with no ortholog for OR11G2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR11G2 Gene

ENSEMBL:
Gene Tree for OR11G2 (if available)
TreeFam:
Gene Tree for OR11G2 (if available)

Paralogs for OR11G2 Gene

Paralogs for OR11G2 Gene

Selected SIMAP similar genes for OR11G2 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for OR11G2 Gene

genes like me logo Genes that share paralogs with OR11G2: view

Variants for OR11G2 Gene

Sequence variations from dbSNP and Humsavar for OR11G2 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
rs1953554 -- 20,196,099(+) CTGGT(A/G)CCATC upstream-variant-2KB
rs2318886 -- 20,198,397(+) CCTTG(C/T)GTAAT downstream-variant-500B
rs2318887 -- 20,198,464(+) TGGCT(C/T)ACGCC downstream-variant-500B
rs4981088 - 20,197,681(+) CCACA(A/G)TCCCC missense, reference
rs4981822 - 20,197,631(+) GTACA(A/T)CCTGC missense, reference

Structural Variations from Database of Genomic Variants (DGV) for OR11G2 Gene

Variant ID Type Subtype PubMed ID
nsv901299 CNV Gain 21882294
esv2751268 CNV Gain 17911159
nsv832739 CNV Gain 17160897
nsv901466 CNV Loss 21882294

Relevant External Links for OR11G2 Gene

HapMap Linkage Disequilibrium report
OR11G2

Disorders for OR11G2 Gene

Relevant External Links for OR11G2

Genetic Association Database (GAD)
OR11G2
genes like me logo Genes that share disorders with OR11G2: view

No data available for UniProtKB/Swiss-Prot for OR11G2 Gene

Publications for OR11G2 Gene

  1. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  3. The DNA sequence and analysis of human chromosome 14. (PMID: 12508121) Heilig R. … Weissenbach J. (Nature 2003) 4

Products for OR11G2 Gene

  • antibodies-online proteins for OR11G2
  • antibodies-online antibodies for OR11G2
  • antibodies-online kits for OR11G2

Sources for OR11G2 Gene

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