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OR11A1 Gene

protein-coding   GIFtS: 50
GCID: GC06M029393

Olfactory Receptor, Family 11, Subfamily A, Member 1

(Previous names: olfactory receptor, family 11, subfamily A, member 2)
(Previous symbol: OR11A2)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Olfactory Receptor, Family 11, Subfamily A, Member 11 2     6M1-182
OR11A21 2 3     dJ994E9.62
Olfactory Receptor, Family 11, Subfamily A, Member 21 2     hs6M1-182
Olfactory Receptor 11A22 3     Olfactory Receptor 11A12
Olfactory Receptor OR6-302 3     Hs6M1-183

External Ids:    HGNC: 81761   Entrez Gene: 265312   Ensembl: ENSG000002046947   UniProtKB: Q9GZK73   

Export aliases for OR11A1 gene to outside databases

Previous GC identifers: GC06M029451 GC06M029165 GC06M029501 GC06M029432 GC06Mo29324


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for OR11A1 Gene:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the
perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled
receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain
structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G
protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the
genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent
of other organisms. (provided by RefSeq, Jul 2008)

GeneCards Summary for OR11A1 Gene:
OR11A1 (olfactory receptor, family 11, subfamily A, member 1) is a protein-coding gene. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity.

UniProtKB/Swiss-Prot: O11A1_HUMAN, Q9GZK7
Function: Odorant receptor (Potential)

Gene Wiki entry for OR11A1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the OR11A1 gene promoter:
         Nkx3-1   Nkx3-1 v4   AML1a   SREBP-1c   Nkx3-1 v1   SREBP-1b   Nkx3-1 v2   SREBP-1a   Nkx3-1 v3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidOR11A1 promoter sequence
   Search Chromatin IP Primers for OR11A1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat OR11A1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p22.2-p21.31   Ensembl cytogenetic band:  6p22.1   HGNC cytogenetic band: 6p22.2-p21.31

OR11A1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
OR11A1 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M029393:  view genomic region     (about GC identifiers)

Start:
29,394,474 bp from pter      End:
29,395,418 bp from pter
Size:
945 bases      Orientation:
minus strand

Selected alternative locations (see all 7):
Chr6-,NT_167247 696,457-698,685      Chr6-,NT_167246 696,260-698,488      Chr6-,NT_113891.2 912,059-914,287     
Chr6-,NT_167248 696,570-698,798      Chr6-,NT_167249 733,813-736,041      Chr6-,NT_167244 696,763-698,991     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: O11A1_HUMAN, Q9GZK7 (See protein sequence)
Recommended Name: Olfactory receptor 11A1  
Size: 315 amino acids; 35250 Da
Secondary accessions: A2BF33 A6NFQ3 B0S7T2 Q5ST16 Q9GZK8

Explore the universe of human proteins at neXtProt for OR11A1: NX_Q9GZK7

Explore proteomics data for OR11A1 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn8
  • HORDE protein sequence for OR11A1

    See OR11A1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_039225.1  
    ENSEMBL proteins: 
     ENSP00000366353   ENSP00000366354   ENSP00000366352  
    Reactome Protein details: Q9GZK7

    OR11A1 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for OR11A1

     
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    Search eBioscience for ELISAs for OR11A1 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    OR11: GPCR / Class A : Olfactory receptors

    3 InterPro protein domains:
     IPR017452 GPCR_Rhodpsn_7TM
     IPR000725 Olfact_rcpt
     IPR000276 GPCR_Rhodpsn

    Graphical View of Domain Structure for InterPro Entry Q9GZK7

    ProtoNet protein and cluster: Q9GZK7

    1 Blocks protein domain: IPB000725 Olfactory receptor signature

    UniProtKB/Swiss-Prot: O11A1_HUMAN, Q9GZK7
    Similarity: Belongs to the G-protein coupled receptor 1 family


    Find genes that share domains with OR11A1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: O11A1_HUMAN, Q9GZK7
    Function: Odorant receptor (Potential)

         Genatlas biochemistry entry for OR11A1:
    olfactory receptor,family 11,subfamily A,member 1,G protein coupled receptor superfamily

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004930G-protein coupled receptor activity IEA--
    GO:0004984olfactory receptor activity IEA--
         
    Find genes that share ontologies with OR11A1           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for OR11A1:
     Decreased Salmonella enterica   Decreased Salmonella enterica  

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for OR11A1
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for OR11A1

    miRNA
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    miRTarBase miRNAs that target OR11A1:
    hsa-mir-335-5p (MIRT016725), hsa-mir-181a-5p (MIRT025086)

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    Search for qRT-PCR Assays for microRNAs that regulate OR11A1
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    Predesigned siRNA for gene silencing in human, mouse, rat OR11A1

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    Sino Biological Human cDNA Clone for OR11A1
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OR11A1

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    O11A1_HUMAN, Q9GZK7: Cell membrane; Multi-pass membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with OR11A1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for OR11A1 About    
    See pathways by source

    SuperPathContained pathways About
    1Olfactory Signaling Pathway
    Olfactory Signaling Pathway0.82
    Olfactory transduction0.82
    2Signaling by GPCR
    Signaling by GPCR0.90
    Signal Transduction0.58
    GPCR downstream signaling0.90
    3Peptide ligand-binding receptors
    GPCRs, Class A Rhodopsin-like0.43


    Find genes that share SuperPaths with OR11A1           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 BioSystems Pathway for OR11A1
        GPCRs, Class A Rhodopsin-like


    1 Reactome Pathway for OR11A1
        Olfactory Signaling Pathway


    1 Kegg Pathway  (Kegg details for OR11A1):
        Olfactory transduction

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for OR11A1
    Interactions:

        Search GeneGlobe Interaction Network for OR11A1

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007186G-protein coupled receptor signaling pathway ----

    Find genes that share ontologies with OR11A1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for OR11A1 (O11A1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for OR11A1 gene: 
    NM_013937.3  

    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000377148 ENST00000377149(uc010jrh.1) ENST00000377147(uc003nmg.3)

    miRNA
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    Block miRNA regulation of human, mouse, rat OR11A1 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate OR11A1
    SwitchGear 3'UTR luciferase reporter plasmidOR11A1 3' UTR sequence
    Inhib. RNA
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OR11A1
    Primer
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat OR11A1
      QuantiTect SYBR Green Assays in human, mouse, rat OR11A1
      QuantiFast Probe-based Assays in human, mouse, rat OR11A1

    9 AceView cDNA sequences:

    NM_030876 AJ459851 AJ459855 AJ459854 NM_013937 AJ459857 AJ459859 BC069149 
    AA936177 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    OR11A1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAAAATTTTA
    OR11A1 Expression
    About this image

    OR11A1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    OR11A1 Protein Expression
        Custom PCR Arrays for OR11A1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OR11A1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for OR11A1 gene from Selected species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Olfr961 , 5 olfactory receptor 961, 5 79.17(n)1
    74.68(a)1
      17 (19.16 cM)5
    2585071  NM_146514.11  NP_666725.11 
     372250915 
    chicken
    (Gallus gallus)
    Aves OR11A16
    olfactory receptor, family 11, subfamily A, member...
    44(a)
    1 ↔ 1
    10(327316-328290)
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    (see all 7)
    Uncharacterized protein
    (see all 7)
    46(a)
    45(a)
    (see all 7)
    1 ↔ many
    1 ↔ many
    (see all 7)
    GL343253.1(349726-350682)
    GL343253.1(792258-793178)


    ENSEMBL Gene Tree for OR11A1 (if available)
    TreeFam Gene Tree for OR11A1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for OR11A1 gene
    Selected SIMAP similar genes for OR11A1 using alignment to 2 protein entries:     O11A1_HUMAN (see all proteins) (see all similar genes):
    OR6B3    OR6B2    OR10R3P    OR6P1    OR6Y1    OR10A4
    OR11G2    OR6N1    OR11H7    OR11L1    OR6B1    OR10A2
    OR10A5    OR11H4    OR11H6    OR13C3    OR13C8    OR1D2

    Find genes that share paralogs with OR11A1           About GenesLikeMe


    2 Pseudogenes.org Pseudogenes for OR11A1
    PGOHUM00000244843 PGOHUM00000242011


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for OR11A1 (see all 79)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs27461481,2
    C,F,H--29392972(+) ACTGAT/CACCAC 1 -- ds500112Minor allele frequency- C:0.04NS EA NA 1084
    rs69222171,2
    C,F,H--29392992(+) ctggaC/Aaataa 1 -- ds50015Minor allele frequency- A:0.03NS EA WA 538
    rs1502265801,2
    C--29393286(+) TGTGGA/GCATGG 1 -- ut310--------
    rs1167635741,2
    C,F--29393314(+) ATTAGT/CCACAG 1 -- ut311Minor allele frequency- C:0.07WA 118
    rs1388838561,2
    C--29393471(+) TGATGC/TTGAAG 1 -- ut310--------
    rs69234051,2
    C,F,H--29393480(+) agctgG/Catggt 1 -- ut315Minor allele frequency- C:0.03NS EA 540
    rs1494142921,2
    C--29393554(+) ACAAGA/GAAAGA 1 -- ut310--------
    rs1475347461,2
    C--29393602(+) AAACAC/TATATC 1 -- ut310--------
    rs168948851,2
    C,F,H--29393704(+) TTCCCA/GAAATA 1 -- ut318Minor allele frequency- G:0.03NA NS EA WA 680
    rs168948891,2
    C,F,H--29393747(+) GCCCAG/CAAGAA 1 -- ut31 ese38Minor allele frequency- C:0.03NA NS EA 680

    HapMap Linkage Disequilibrium report for OR11A1 ( 29394474 - 29395418 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for OR11A1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv830624CNV Loss17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing OR11A1
    DNA2.0 Custom Variant and Variant Library Synthesis for OR11A1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with OR11A1           About GenesLikeMe

    Genetic Association Database (GAD): OR11A1
    Human Genome Epidemiology (HuGE) Navigator: OR11A1 (3 documents)

    Export disorders for OR11A1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for OR11A1 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with OR11A1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    2. High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. (PubMed id 19851445)1, 4 Barcellos L.F....Criswell L.A. (PLoS Genet. 2009)
    3. The human olfactory receptor gene family. (PubMed id 14983052)1, 2 Malnic B.... Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004)
    4. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (Nature 2003)
    5. Complex transcription and splicing of odorant receptor genes. (PubMed id 12637542)1, 2 Volz A.... Ziegler A. (J. Biol. Chem. 2003)
    6. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PubMed id 17903299)4 Kathiresan S....Cupples L.A. (BMC Med. Genet. 2007)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    8. (PubMed id )2 

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 26531 HGNC: 8176 AceView: OR11A1andOR5V1 Ensembl:ENSG00000204694 euGenes: HUgn26531
    ECgene: OR11A1 Kegg: 26531 H-InvDB: OR11A1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for OR11A1 Pharmacogenomics, SNPs, Pathways
    HORDE entry for OR11A1 The Human Olfactory Receptor Data Explorer at the Weizmann Institute of Science

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for OR11A1 gene:
    Search GeneIP for patents involving OR11A1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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