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Aliases for OR10Z1 Gene

Aliases for OR10Z1 Gene

  • Olfactory Receptor, Family 10, Subfamily Z, Member 1 2 3
  • Olfactory Receptor OR1-15 3 4
  • Olfactory Receptor 10Z1 3
  • OR1-15 3

External Ids for OR10Z1 Gene

Summaries for OR10Z1 Gene

Entrez Gene Summary for OR10Z1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR10Z1 Gene

OR10Z1 (Olfactory Receptor, Family 10, Subfamily Z, Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR10X1.

UniProtKB/Swiss-Prot for OR10Z1 Gene

  • Odorant receptor.

Gene Wiki entry for OR10Z1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR10Z1 Gene

Genomics for OR10Z1 Gene

Genomic Location for OR10Z1 Gene

Start:
158,606,439 bp from pter
End:
158,607,380 bp from pter
Size:
942 bases
Orientation:
Plus strand

Genomic View for OR10Z1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR10Z1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR10Z1 Gene

Regulatory Elements for OR10Z1 Gene

Proteins for OR10Z1 Gene

  • Protein details for OR10Z1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGY1-O10Z1_HUMAN
    Recommended name:
    Olfactory receptor 10Z1
    Protein Accession:
    Q8NGY1
    Secondary Accessions:
    • Q5VYL0
    • Q6IFR7

    Protein attributes for OR10Z1 Gene

    Size:
    313 amino acids
    Molecular mass:
    34609 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR10Z1 Gene

Proteomics data for OR10Z1 Gene at MOPED

Post-translational modifications for OR10Z1 Gene

  • Modification sites at PhosphoSitePlus
  • Glycosylation at Asn5

Other Protein References for OR10Z1 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR10Z1 Gene

Domains for OR10Z1 Gene

Gene Families for OR10Z1 Gene

HGNC:
  • OR10 :GPCR / Class A : Olfactory receptors

Protein Domains for OR10Z1 Gene

UniProtKB/Swiss-Prot:

O10Z1_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q8NGY1
genes like me logo Genes that share domains with OR10Z1: view

Function for OR10Z1 Gene

Molecular function for OR10Z1 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR10Z1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004888 transmembrane signaling receptor activity IBA --
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR10Z1: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR10Z1 Gene

Localization for OR10Z1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR10Z1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR10Z1 Gene COMPARTMENTS Subcellular localization image for OR10Z1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR10Z1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR10Z1: view

Pathways for OR10Z1 Gene

genes like me logo Genes that share pathways with OR10Z1: view

Pathways by source for OR10Z1 Gene

Interacting Proteins for OR10Z1 Gene

STRING Interaction Network Preview (showing 3 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000354707%0d%0a9606.ENSP00000334051%0d%0a9606.ENSP00000269260%0d%0a9606.ENSP00000317578%0d%0a
Selected Interacting proteins: ENSP00000354707 for OR10Z1 Gene via STRING

Gene Ontology (GO) - Biological Process for OR10Z1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0050907 detection of chemical stimulus involved in sensory perception IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR10Z1: view

Transcripts for OR10Z1 Gene

mRNA/cDNA for OR10Z1 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR10Z1 Gene

No ASD Table

Relevant External Links for OR10Z1 Gene

GeneLoc Exon Structure for
OR10Z1
ECgene alternative splicing isoforms for
OR10Z1

Expression for OR10Z1 Gene

mRNA expression in normal human tissues for OR10Z1 Gene

SOURCE GeneReport for Unigene cluster for OR10Z1 Gene Hs.553590

genes like me logo Genes that share expressions with OR10Z1: view

Orthologs for OR10Z1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR10Z1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC469532 36
  • 99.25 (n)
  • 99.04 (a)
OR10Z1 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia OR10Z1 36
  • 85.3 (n)
  • 85.62 (a)
OR10Z1 37
  • 86 (a)
OneToOne
dog
(Canis familiaris)
Mammalia OR10Z1 36
  • 85.41 (n)
  • 88.82 (a)
OR10Z1 37
  • 89 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Olfr419 36
  • 83.39 (n)
  • 87.54 (a)
Olfr419 16
Olfr419 37
  • 88 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia OR10Z1 37
  • 78 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Olr1597 36
  • 82 (n)
  • 85.94 (a)
Species with no ortholog for OR10Z1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR10Z1 Gene

ENSEMBL:
Gene Tree for OR10Z1 (if available)
TreeFam:
Gene Tree for OR10Z1 (if available)

Paralogs for OR10Z1 Gene

Selected SIMAP similar genes for OR10Z1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR10Z1: view

Variants for OR10Z1 Gene

Sequence variations from dbSNP and Humsavar for OR10Z1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs857683 -- 158,604,795(+) GGGGA(A/G)CAGCT upstream-variant-2KB
rs857684 -- 158,605,939(+) ATAAA(C/T)GTATA upstream-variant-2KB
rs857685 - 158,607,319(+) AAGGA(A/C)TAGGG reference, missense
rs860772 -- 158,606,310(+) AATCA(C/G)AGCTG upstream-variant-2KB
rs2427808 -- 158,607,377(+) AAAGG(A/T)TGAAG reference, synonymous-codon

Relevant External Links for OR10Z1 Gene

HapMap Linkage Disequilibrium report
OR10Z1
Human Gene Mutation Database (HGMD)
OR10Z1

No data available for Structural Variations from Database of Genomic Variants (DGV) for OR10Z1 Gene

Disorders for OR10Z1 Gene

Relevant External Links for OR10Z1

Genetic Association Database (GAD)
OR10Z1
Human Genome Epidemiology (HuGE) Navigator
OR10Z1
genes like me logo Genes that share disorders with OR10Z1: view

No data available for UniProtKB/Swiss-Prot for OR10Z1 Gene

Publications for OR10Z1 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  3. An approach based on a genome-wide association study reveals candidate loci for narcolepsy. (PMID: 20677014) Shimada M. … Tokunaga K. (Hum. Genet. 2010) 3 49
  4. Seventy-five genetic loci influencing the human red blood cell. (PMID: 23222517) van der Harst P. … Chambers J.C. (Nature 2012) 3

Products for OR10Z1 Gene

Sources for OR10Z1 Gene

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