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Aliases for OR10X1 Gene

Aliases for OR10X1 Gene

  • Olfactory Receptor Family 10 Subfamily X Member 1 (Gene/Pseudogene) 2 3 5
  • Olfactory Receptor OR1-14 3 4
  • OR10X1P 3 4
  • Olfactory Receptor, Family 10, Subfamily X, Member 1 (Gene/Pseudogene) 2
  • Olfactory Receptor, Family 10, Subfamily X, Member 1 Pseudogene 3
  • Olfactory Receptor, Family 10, Subfamily X, Member 1 2
  • Olfactory Receptor OR1-13 Pseudogene 3
  • OR1-13 3
  • OR1-14 3

External Ids for OR10X1 Gene

Previous HGNC Symbols for OR10X1 Gene

  • OR10X1P

Previous GeneCards Identifiers for OR10X1 Gene

  • GC01M155766
  • GC01M155361
  • GC01M156815

Summaries for OR10X1 Gene

Entrez Gene Summary for OR10X1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jun 2015]

GeneCards Summary for OR10X1 Gene

OR10X1 (Olfactory Receptor Family 10 Subfamily X Member 1 (Gene/Pseudogene)) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR10H1.

UniProtKB/Swiss-Prot for OR10X1 Gene

  • Odorant receptor.

Gene Wiki entry for OR10X1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR10X1 Gene

Genomics for OR10X1 Gene

Regulatory Elements for OR10X1 Gene

Enhancers for OR10X1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around OR10X1 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR10X1 Gene

158,578,919 bp from pter
158,579,899 bp from pter
981 bases
Minus strand

Genomic View for OR10X1 Gene

Genes around OR10X1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR10X1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR10X1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR10X1 Gene

Proteins for OR10X1 Gene

  • Protein details for OR10X1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 10X1
    Protein Accession:
    Secondary Accessions:
    • Q6IFR8

    Protein attributes for OR10X1 Gene

    326 amino acids
    Molecular mass:
    36446 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAC05862.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAH72417.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for OR10X1 Gene

Proteomics data for OR10X1 Gene at MOPED

Post-translational modifications for OR10X1 Gene

  • Glycosylation at Asn 21 and Asn 209
  • Modification sites at PhosphoSitePlus

Other Protein References for OR10X1 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

Antibody Products

  • Santa Cruz Biotechnology (SCBT) Antibodies for OR10X1

No data available for DME Specific Peptides for OR10X1 Gene

Domains & Families for OR10X1 Gene

Gene Families for OR10X1 Gene

Protein Domains for OR10X1 Gene

Suggested Antigen Peptide Sequences for OR10X1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR10X1: view

Function for OR10X1 Gene

Molecular function for OR10X1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.
genes like me logo Genes that share phenotypes with OR10X1: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR10X1 Gene

Localization for OR10X1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR10X1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR10X1 Gene COMPARTMENTS Subcellular localization image for OR10X1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR10X1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005887 integral component of plasma membrane IBA --
genes like me logo Genes that share ontologies with OR10X1: view

Pathways & Interactions for OR10X1 Gene

genes like me logo Genes that share pathways with OR10X1: view

Pathways by source for OR10X1 Gene

Interacting Proteins for OR10X1 Gene

STRING Interaction Network Preview (showing 3 interactants - click image to see details)
Selected Interacting proteins: ENSP00000357132 for OR10X1 Gene via STRING

Gene Ontology (GO) - Biological Process for OR10X1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR10X1: view

No data available for SIGNOR curated interactions for OR10X1 Gene

Drugs & Compounds for OR10X1 Gene

No Compound Related Data Available

Transcripts for OR10X1 Gene

mRNA/cDNA for OR10X1 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR10X1 Gene

No ASD Table

Relevant External Links for OR10X1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR10X1 Gene

mRNA expression in normal human tissues for OR10X1 Gene

Protein differential expression in normal tissues from HIPED for OR10X1 Gene

This gene is overexpressed in Adrenal (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for OR10X1 Gene

SOURCE GeneReport for Unigene cluster for OR10X1 Gene Hs.553589

genes like me logo Genes that share expression patterns with OR10X1: view

Protein tissue co-expression partners for OR10X1 Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for OR10X1 Gene

Orthologs for OR10X1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR10X1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia LOC513494 35
  • 86.14 (n)
  • 84.82 (a)
-- 36
  • 80 (a)
-- 36
  • 81 (a)
-- 36
  • 81 (a)
(Canis familiaris)
Mammalia OR10X1 35
  • 83.44 (n)
  • 82.69 (a)
OR10X1 36
  • 82 (a)
(Mus musculus)
Mammalia Olfr417 35
  • 84.26 (n)
  • 83.06 (a)
Olfr417 16
Olfr248 36
  • 78 (a)
Olfr417 36
  • 83 (a)
(Pan troglodytes)
Mammalia LOC469531 35
  • 98.57 (n)
  • 96.93 (a)
OR10X1 36
  • 97 (a)
(Rattus norvegicus)
Mammalia Olr1598 35
  • 84.25 (n)
  • 83.17 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 71 (a)
-- 36
  • 74 (a)
Species with no ortholog for OR10X1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR10X1 Gene

Gene Tree for OR10X1 (if available)
Gene Tree for OR10X1 (if available)

Paralogs for OR10X1 Gene

(447) SIMAP similar genes for OR10X1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR10X1: view

Variants for OR10X1 Gene

Polymorphic Variants from UniProtKB/Swiss-Prot for OR10X1 Gene

A stop codon at position Trp-66 in the gene coding for this protein is responsible for functional diversity thus producing a pseudogene. The stop codon is more frequent in African-Americans than in non-Africans.

Sequence variations from dbSNP and Humsavar for OR10X1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs863363 - 158,579,721(+) TGATG(A/G)TCAGA reference, missense
rs950164 - 158,579,659(-) TTAGT(G/T)CACTC reference, missense
rs7550131 - 158,579,386(+) AAGAG(A/G/T)GATAA reference, missense
rs16840360 - 158,579,362(+) CCTGA(A/G)TATCA reference, missense
rs863360 -- 158,579,474(+) TTACA(A/G)ATGGC reference, synonymous-codon

Variation tolerance for OR10X1 Gene

Residual Variation Intolerance Score: 83.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.22; 69.92% of all genes are more intolerant (likely to be disease-causing)

No data available for Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for OR10X1 Gene

Disorders for OR10X1 Gene

Relevant External Links for OR10X1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for OR10X1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR10X1 Gene

Publications for OR10X1 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 67
  2. Personal receptor repertoires: olfaction as a model. (PMID: 22908908) Olender T. … Lancet D. (BMC Genomics 2012) 3
  3. A probabilistic classifier for olfactory receptor pseudogenes. (PMID: 16939646) Menashe I. … Lancet D. (BMC Bioinformatics 2006) 3
  4. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3
  5. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3

Products for OR10X1 Gene

Sources for OR10X1 Gene