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Aliases for OR10X1 Gene

Aliases for OR10X1 Gene

  • Olfactory Receptor, Family 10, Subfamily X, Member 1 (Gene/Pseudogene) 2 3
  • Olfactory Receptor OR1-14 3 4
  • OR10X1P 3 4
  • Olfactory Receptor, Family 10, Subfamily X, Member 1 Pseudogene 3
  • Olfactory Receptor, Family 10, Subfamily X, Member 1 2
  • Olfactory Receptor OR1-13 Pseudogene 3
  • Olfactory Receptor 10X1 3
  • OR1-13 3
  • OR1-14 3

External Ids for OR10X1 Gene

Previous Symbols for OR10X1 Gene

  • OR10X1P

Summaries for OR10X1 Gene

Entrez Gene Summary for OR10X1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR10X1 Gene

OR10X1 (Olfactory Receptor, Family 10, Subfamily X, Member 1 (Gene/Pseudogene)) is a Protein Coding gene. Diseases associated with OR10X1 include basal cell carcinoma. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR10H1.

UniProtKB/Swiss-Prot for OR10X1 Gene

  • Odorant receptor.

Gene Wiki entry for OR10X1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR10X1 Gene

Genomics for OR10X1 Gene

Genomic Location for OR10X1 Gene

Start:
158,578,919 bp from pter
End:
158,579,899 bp from pter
Size:
981 bases
Orientation:
Minus strand

Genomic View for OR10X1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR10X1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR10X1 Gene

Regulatory Elements for OR10X1 Gene

Proteins for OR10X1 Gene

  • Protein details for OR10X1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGY0-O10X1_HUMAN
    Recommended name:
    Olfactory receptor 10X1
    Protein Accession:
    Q8NGY0
    Secondary Accessions:
    • Q6IFR8

    Protein attributes for OR10X1 Gene

    Size:
    326 amino acids
    Molecular mass:
    36446 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC05862.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAH72417.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for OR10X1 Gene

Proteomics data for OR10X1 Gene at MOPED

Post-translational modifications for OR10X1 Gene

  • Glycosylation at Asn21 and Asn209

Other Protein References for OR10X1 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR10X1 Gene

Domains for OR10X1 Gene

Gene Families for OR10X1 Gene

HGNC:
  • OR10 :GPCR / Class A : Olfactory receptors

Protein Domains for OR10X1 Gene

UniProtKB/Swiss-Prot:

O10X1_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q8NGY0
genes like me logo Genes that share domains with OR10X1: view

Function for OR10X1 Gene

Molecular function for OR10X1 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR10X1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR10X1: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR10X1 Gene

Localization for OR10X1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR10X1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR10X1 Gene COMPARTMENTS Subcellular localization image for OR10X1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR10X1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR10X1: view

Pathways for OR10X1 Gene

genes like me logo Genes that share pathways with OR10X1: view

Pathways by source for OR10X1 Gene

Interacting Proteins for OR10X1 Gene

STRING Interaction Network Preview (showing 3 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000357132%0d%0a9606.ENSP00000334051%0d%0a9606.ENSP00000269260%0d%0a9606.ENSP00000317578%0d%0a
Selected Interacting proteins: ENSP00000357132 for OR10X1 Gene via STRING

Gene Ontology (GO) - Biological Process for OR10X1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR10X1: view

Transcripts for OR10X1 Gene

mRNA/cDNA for OR10X1 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR10X1 Gene

No ASD Table

Relevant External Links for OR10X1 Gene

GeneLoc Exon Structure for
OR10X1
ECgene alternative splicing isoforms for
OR10X1

Expression for OR10X1 Gene

mRNA expression in normal human tissues for OR10X1 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for OR10X1 Gene

SOURCE GeneReport for Unigene cluster for OR10X1 Gene Hs.553589

genes like me logo Genes that share expressions with OR10X1: view

Orthologs for OR10X1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR10X1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC469531 36
  • 98.57 (n)
  • 96.93 (a)
OR10X1 37
  • 97 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 37
  • 80 (a)
OneToMany
-- 37
  • 81 (a)
OneToMany
-- 37
  • 81 (a)
OneToMany
LOC513494 36
  • 86.14 (n)
  • 84.82 (a)
dog
(Canis familiaris)
Mammalia OR10X1 36
  • 83.44 (n)
  • 82.69 (a)
OR10X1 37
  • 82 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Olfr248 37
  • 78 (a)
OneToMany
Olfr417 36
  • 84.26 (n)
  • 83.06 (a)
Olfr417 16
Olfr417 37
  • 83 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 71 (a)
OneToMany
-- 37
  • 74 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Olr1598 36
  • 84.25 (n)
  • 83.17 (a)
Species with no ortholog for OR10X1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR10X1 Gene

ENSEMBL:
Gene Tree for OR10X1 (if available)
TreeFam:
Gene Tree for OR10X1 (if available)

Paralogs for OR10X1 Gene

Selected SIMAP similar genes for OR10X1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR10X1: view

Variants for OR10X1 Gene

Polymorphic Variants from UniProtKB/Swiss-Prot for OR10X1 Gene

Q8NGY0-O10X1_HUMAN
A stop codon at position Trp-66 in the gene coding for this protein is responsible for functional diversity thus producing a pseudogene. The stop codon is more frequent in African-Americans than in non-Africans

Sequence variations from dbSNP and Humsavar for OR10X1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs863360 -- 158,579,474(+) TTACA(A/G)ATGGC reference, synonymous-codon
rs863361 -- 158,579,630(+) GTCAG(C/T)GTATA synonymous-codon, reference
rs863362 -- 158,579,702(+) TCCAC(C/T)CAAGT stop-gained, reference
rs863363 - 158,579,721(+) TGATG(A/G)TCAGA missense, reference
rs863364 -- 158,581,447(+) ACAAG(A/T)TTCTT upstream-variant-2KB

Relevant External Links for OR10X1 Gene

HapMap Linkage Disequilibrium report
OR10X1

No data available for Structural Variations from Database of Genomic Variants (DGV) for OR10X1 Gene

Disorders for OR10X1 Gene

(1) MalaCards Diseases for OR10X1 Gene

Search for OR10X1 Gene in MalaCards »

(1) University of Copenhagen DISEASES for OR10X1 Gene

genes like me logo Genes that share disorders with OR10X1: view

No data available for UniProtKB/Swiss-Prot for OR10X1 Gene

Publications for OR10X1 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  3. Different noses for different people. (PMID: 12730696) Menashe I. … Gilad Y. (Nat. Genet. 2003) 4
  4. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3

Products for OR10X1 Gene

Sources for OR10X1 Gene

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