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Aliases for OR10V1 Gene

Aliases for OR10V1 Gene

  • Olfactory Receptor Family 10 Subfamily V Member 1 2 3 5
  • Olfactory Receptor OR11-256 3 4
  • Olfactory Receptor, Family 10, Subfamily V, Member 1 2
  • Olfactory Receptor 10V1 3
  • OR11-256 3

External Ids for OR10V1 Gene

Previous GeneCards Identifiers for OR10V1 Gene

  • GC11U990577
  • GC11M059256
  • GC11M059236
  • GC11M059480

Summaries for OR10V1 Gene

Entrez Gene Summary for OR10V1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR10V1 Gene

OR10V1 (Olfactory Receptor Family 10 Subfamily V Member 1) is a Protein Coding gene. Among its related pathways are Olfactory Signaling Pathway and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and odorant binding. An important paralog of this gene is OR10Q1.

UniProtKB/Swiss-Prot for OR10V1 Gene

  • Odorant receptor.

Gene Wiki entry for OR10V1 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR10V1 Gene

Genomics for OR10V1 Gene

Regulatory Elements for OR10V1 Gene

Enhancers for OR10V1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11G059680 1.2 Ensembl ENCODE 12.6 +32.7 32652 2.0 FOXA2 ARNT WRNIP1 ARID4B TCF12 GATA2 NCOA1 REST PPARG KAT8 STX3 RN7SKP192 OR10V1 OR5A2 LOC105369318 GC11P059703
GH11G060127 1.1 FANTOM5 ENCODE 2.1 -413.6 -413599 0.9 CBX3 ATF1 JUN BACH1 ZNF644 CHAMP1 FOSL1 FOXM1 ZNF766 ZNF316 MS4A2 MS4A13 OR10V1 STX3 LOC105369319
GH11G059266 0.5 FANTOM5 dbSUPER 1.4 +447.2 447185 0.1 OR4D10 OR4D9 OR4D6 OR10V1 OR5A1 GC11M059264 ENSG00000214797
GH11G059705 1.3 Ensembl ENCODE 0.4 +6.9 6876 3.6 PKNOX1 ATF1 ARNT SIN3A E2F7 TCF12 ZNF766 ELK1 GATA2 FOS STX3 MS4A6A RN7SKP192 OR10V1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around OR10V1 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR10V1 Gene

Chromosome:
11
Start:
59,712,823 bp from pter
End:
59,713,864 bp from pter
Size:
1,042 bases
Orientation:
Minus strand

Genomic View for OR10V1 Gene

Genes around OR10V1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR10V1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR10V1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR10V1 Gene

Proteins for OR10V1 Gene

  • Protein details for OR10V1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGI7-O10V1_HUMAN
    Recommended name:
    Olfactory receptor 10V1
    Protein Accession:
    Q8NGI7
    Secondary Accessions:
    • Q6IFD9
    • Q96R50

    Protein attributes for OR10V1 Gene

    Size:
    309 amino acids
    Molecular mass:
    34746 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR10V1 Gene

Post-translational modifications for OR10V1 Gene

Other Protein References for OR10V1 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR10V1 Gene

Domains & Families for OR10V1 Gene

Gene Families for OR10V1 Gene

Protein Domains for OR10V1 Gene

Suggested Antigen Peptide Sequences for OR10V1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NGI7

UniProtKB/Swiss-Prot:

O10V1_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR10V1: view

Function for OR10V1 Gene

Molecular function for OR10V1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR10V1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR10V1: view
genes like me logo Genes that share phenotypes with OR10V1: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR10V1 Gene

Localization for OR10V1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR10V1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OR10V1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR10V1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR10V1: view

Pathways & Interactions for OR10V1 Gene

genes like me logo Genes that share pathways with OR10V1: view

Pathways by source for OR10V1 Gene

Interacting Proteins for OR10V1 Gene

Gene Ontology (GO) - Biological Process for OR10V1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IEA --
GO:0050896 response to stimulus IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR10V1: view

No data available for SIGNOR curated interactions for OR10V1 Gene

Drugs & Compounds for OR10V1 Gene

No Compound Related Data Available

Transcripts for OR10V1 Gene

mRNA/cDNA for OR10V1 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR10V1 Gene

No ASD Table

Relevant External Links for OR10V1 Gene

GeneLoc Exon Structure for
OR10V1
ECgene alternative splicing isoforms for
OR10V1

Expression for OR10V1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OR10V1 Gene

NURSA nuclear receptor signaling pathways regulating expression of OR10V1 Gene:

OR10V1

SOURCE GeneReport for Unigene cluster for OR10V1 Gene:

Hs.589001
genes like me logo Genes that share expression patterns with OR10V1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR10V1 Gene

Orthologs for OR10V1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR10V1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia OR10V1 35
  • 99 (a)
OneToOne
LOC736272 34
  • 98.92 (n)
dog
(Canis familiaris)
Mammalia OR10V1 34 35
  • 87.59 (n)
mouse
(Mus musculus)
Mammalia Or10v1 55 Olfr1420 34 16 35
  • 87.49 (n)
Or10q3 55 Olfr1419
  • chr19:11,870,186-11,871,214
rat
(Rattus norvegicus)
Mammalia Olr319 34
  • 85.98 (n)
cow
(Bos Taurus)
Mammalia OR10V1 34 35
  • 83.66 (n)
oppossum
(Monodelphis domestica)
Mammalia OR10V1 35
  • 77 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia OR10V1 35
  • 70 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 41 (a)
ManyToMany
Species where no ortholog for OR10V1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR10V1 Gene

ENSEMBL:
Gene Tree for OR10V1 (if available)
TreeFam:
Gene Tree for OR10V1 (if available)

Paralogs for OR10V1 Gene

Paralogs for OR10V1 Gene

(452) SIMAP similar genes for OR10V1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR10V1: view

Variants for OR10V1 Gene

Sequence variations from dbSNP and Humsavar for OR10V1 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1000361572 -- 59,712,516(+) TTTTT(C/T)TGGCA downstream-variant-500B
rs1000553492 -- 59,714,068(+) GACTG(-/A)AAAAA upstream-variant-2KB
rs1001479678 -- 59,713,134(+) GTAGG(C/T)TTGCT reference, missense
rs1004673408 -- 59,713,429(+) AAGGA(C/G)CAGCT reference, missense
rs1005809040 -- 59,714,737(+) TCAAA(A/G)AGTCT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR10V1 Gene

Variant ID Type Subtype PubMed ID
nsv517878 CNV loss 19592680

Variation tolerance for OR10V1 Gene

Residual Variation Intolerance Score: 90% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.70; 83.03% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR10V1 Gene

Human Gene Mutation Database (HGMD)
OR10V1
SNPedia medical, phenotypic, and genealogical associations of SNPs for
OR10V1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR10V1 Gene

Disorders for OR10V1 Gene

Relevant External Links for OR10V1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OR10V1

No disorders were found for OR10V1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR10V1 Gene

Publications for OR10V1 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 64
  2. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4 64

Products for OR10V1 Gene

Sources for OR10V1 Gene

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