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Aliases for OR10S1 Gene

Aliases for OR10S1 Gene

  • Olfactory Receptor Family 10 Subfamily S Member 1 2 3 5
  • Olfactory Receptor OR11-279 3 4
  • Olfactory Receptor, Family 10, Subfamily S, Member 1 2
  • Olfactory Receptor 10S1 3
  • OR11-279 3

External Ids for OR10S1 Gene

Previous GeneCards Identifiers for OR10S1 Gene

  • GC11U990360
  • GC11M123386
  • GC11M123353
  • GC11M123849

Summaries for OR10S1 Gene

Entrez Gene Summary for OR10S1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR10S1 Gene

OR10S1 (Olfactory Receptor Family 10 Subfamily S Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR10G6.

UniProtKB/Swiss-Prot for OR10S1 Gene

  • Odorant receptor.

Gene Wiki entry for OR10S1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR10S1 Gene

Genomics for OR10S1 Gene

Regulatory Elements for OR10S1 Gene

Enhancers for OR10S1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11F124008 0.3 FANTOM5 11.2 -30.9 -30894 0.4 OR8D1 OR4D5 OR10G9 OR8D4 OR10G4 OR6M1 OR8G1 OR10S1 OR8D2 OR6X1
GH11F123695 0.4 FANTOM5 1.5 +282.4 282448 0.4 OR6X1 OR8D4 OR10G4 OR4D5 OR10G7 SCN3B ZNF202 OR6M1 OR6T1 OR10G9
GH11F123583 0.3 FANTOM5 1.5 +393.9 393913 0.4 ATF1 SIN3A FEZF1 ETV6 FOS ZEB2 ELF1 MAFF ZSCAN16 IKZF1 OR10G7 OR6X1 OR10G4 OR6T1 OR4D5 OR6M1 OR8D4 OR10S1 GC11M123576 GC11M123593
GH11F123740 0.9 FANTOM5 ENCODE 1.4 +235.7 235708 3.8 CREB3L1 MLX ARID4B SIN3A DMAP1 YY1 ZNF143 KLF13 ZNF263 SP3 ZNF202 OR6X1 OR10G7 OR6M1 OR10G4 OR8G2 OR4D5 TMEM225 OR6T1 OR8D4
GH11F123977 0.2 ENCODE 0.8 -0.3 -349 2.0 CEBPB NFE2 ZEB2 TRIM24 EP300 EMSY ZNF202 OR10S1 OR6T1
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around OR10S1 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR10S1 Gene

123,976,661 bp from pter
123,977,781 bp from pter
1,121 bases
Minus strand

Genomic View for OR10S1 Gene

Genes around OR10S1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR10S1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR10S1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR10S1 Gene

Proteins for OR10S1 Gene

  • Protein details for OR10S1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 10S1
    Protein Accession:
    Secondary Accessions:
    • B9EH43
    • Q6IEV3
    • Q96R78

    Protein attributes for OR10S1 Gene

    331 amino acids
    Molecular mass:
    36501 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAC05978.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for OR10S1 Gene

Post-translational modifications for OR10S1 Gene

  • Glycosylation at Asn 18
  • Modification sites at PhosphoSitePlus

Other Protein References for OR10S1 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR10S1 Gene

Domains & Families for OR10S1 Gene

Gene Families for OR10S1 Gene

Protein Domains for OR10S1 Gene

Suggested Antigen Peptide Sequences for OR10S1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR10S1: view

Function for OR10S1 Gene

Molecular function for OR10S1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR10S1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR10S1: view
genes like me logo Genes that share phenotypes with OR10S1: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR10S1 Gene

Localization for OR10S1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR10S1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR10S1 Gene COMPARTMENTS Subcellular localization image for OR10S1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR10S1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR10S1: view

Pathways & Interactions for OR10S1 Gene

genes like me logo Genes that share pathways with OR10S1: view

Pathways by source for OR10S1 Gene

Gene Ontology (GO) - Biological Process for OR10S1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IEA,IBA --
GO:0050896 response to stimulus IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR10S1: view

No data available for SIGNOR curated interactions for OR10S1 Gene

Transcripts for OR10S1 Gene

mRNA/cDNA for OR10S1 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR10S1 Gene

No ASD Table

Relevant External Links for OR10S1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR10S1 Gene

mRNA expression in normal human tissues for OR10S1 Gene

NURSA nuclear receptor signaling pathways regulating expression of OR10S1 Gene:


SOURCE GeneReport for Unigene cluster for OR10S1 Gene:

genes like me logo Genes that share expression patterns with OR10S1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for OR10S1 Gene

Orthologs for OR10S1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR10S1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC466818 34
  • 99.07 (n)
(Canis familiaris)
Mammalia OR10S1 34 35
  • 86.1 (n)
(Bos Taurus)
Mammalia OR10S1 34
  • 85.43 (n)
(Mus musculus)
Mammalia Or10s1 55 Olfr982 34 16 35
  • 83.92 (n)
(Rattus norvegicus)
Mammalia Olr1337 34
  • 82.38 (n)
(Monodelphis domestica)
Mammalia OR10S1 35
  • 74 (a)
Species where no ortholog for OR10S1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR10S1 Gene

Gene Tree for OR10S1 (if available)
Gene Tree for OR10S1 (if available)

Paralogs for OR10S1 Gene

Paralogs for OR10S1 Gene

(443) SIMAP similar genes for OR10S1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR10S1: view

Variants for OR10S1 Gene

Sequence variations from dbSNP and Humsavar for OR10S1 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs10790619 -- 123,978,651(+) AAAAA(A/T)TCGAA upstream-variant-2KB
rs10893117 -- 123,976,685(+) GTTTT(C/G)ATAGC downstream-variant-500B
rs10893118 -- 123,978,275(+) TGAAT(A/C)ATTAT upstream-variant-2KB
rs10893119 -- 123,978,551(+) CACCT(A/T)GATTT upstream-variant-2KB
rs111286459 -- 123,978,724(+) GAATT(A/G)TCTGT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR10S1 Gene

Variant ID Type Subtype PubMed ID
dgv82n21 CNV gain 19592680
esv2761716 CNV loss 21179565

Variation tolerance for OR10S1 Gene

Residual Variation Intolerance Score: 75.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 11.80; 93.39% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR10S1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR10S1 Gene

Disorders for OR10S1 Gene

Relevant External Links for OR10S1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for OR10S1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR10S1 Gene

Publications for OR10S1 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 64
  2. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4 64
  3. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 4 64
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for OR10S1 Gene

Sources for OR10S1 Gene

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