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Aliases for OR10R2 Gene

Aliases for OR10R2 Gene

  • Olfactory Receptor Family 10 Subfamily R Member 2 2 3 5
  • Olfactory Receptor, Family 10, Subfamily R, Member 2 2 3
  • Olfactory Receptor OR1-8 3 4
  • OR10R2Q 3
  • OR1-8 3

External Ids for OR10R2 Gene

Previous GeneCards Identifiers for OR10R2 Gene

  • GC01U990367
  • GC01P155659
  • GC01P155250
  • GC01P156716

Summaries for OR10R2 Gene

Entrez Gene Summary for OR10R2 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR10R2 Gene

OR10R2 (Olfactory Receptor Family 10 Subfamily R Member 2) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and transmembrane signaling receptor activity. An important paralog of this gene is OR10H1.

UniProtKB/Swiss-Prot for OR10R2 Gene

  • Odorant receptor.

Gene Wiki entry for OR10R2 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR10R2 Gene

Genomics for OR10R2 Gene

Regulatory Elements for OR10R2 Gene

Enhancers for OR10R2 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around OR10R2 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR10R2 Gene

158,479,878 bp from pter
158,480,885 bp from pter
1,008 bases
Plus strand

Genomic View for OR10R2 Gene

Genes around OR10R2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR10R2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR10R2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR10R2 Gene

Proteins for OR10R2 Gene

  • Protein details for OR10R2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 10R2
    Protein Accession:
    Secondary Accessions:
    • Q5VWM8
    • Q6IFS1
    • Q96R61

    Protein attributes for OR10R2 Gene

    335 amino acids
    Molecular mass:
    37486 Da
    Quaternary structure:
    No Data Available
    • Sequence=CAH70559.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for OR10R2 Gene

Proteomics data for OR10R2 Gene at MOPED

Post-translational modifications for OR10R2 Gene

  • Glycosylation at Asn 25
  • Modification sites at PhosphoSitePlus

Other Protein References for OR10R2 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR10R2 Gene

Domains & Families for OR10R2 Gene

Gene Families for OR10R2 Gene

Protein Domains for OR10R2 Gene

Suggested Antigen Peptide Sequences for OR10R2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR10R2: view

Function for OR10R2 Gene

Molecular function for OR10R2 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR10R2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
genes like me logo Genes that share ontologies with OR10R2: view
genes like me logo Genes that share phenotypes with OR10R2: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR10R2 Gene

Localization for OR10R2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR10R2 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR10R2 Gene COMPARTMENTS Subcellular localization image for OR10R2 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR10R2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA,IBA --
genes like me logo Genes that share ontologies with OR10R2: view

Pathways & Interactions for OR10R2 Gene

genes like me logo Genes that share pathways with OR10R2: view

Pathways by source for OR10R2 Gene

Interacting Proteins for OR10R2 Gene

Gene Ontology (GO) - Biological Process for OR10R2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR10R2: view

No data available for SIGNOR curated interactions for OR10R2 Gene

Drugs & Compounds for OR10R2 Gene

No Compound Related Data Available

Transcripts for OR10R2 Gene

mRNA/cDNA for OR10R2 Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR10R2 Gene

Olfactory receptor, family 10, subfamily R, member 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for OR10R2 Gene

No ASD Table

Relevant External Links for OR10R2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR10R2 Gene

mRNA expression in normal human tissues for OR10R2 Gene

Protein differential expression in normal tissues from HIPED for OR10R2 Gene

This gene is overexpressed in Esophagus (46.6) and Kidney (22.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for OR10R2 Gene

SOURCE GeneReport for Unigene cluster for OR10R2 Gene Hs.451913

genes like me logo Genes that share expression patterns with OR10R2: view

Protein tissue co-expression partners for OR10R2 Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for OR10R2 Gene

Orthologs for OR10R2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR10R2 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia OR10R2 35
  • 86.6 (n)
  • 90.51 (a)
OR10R2 36
  • 88 (a)
(Pan troglodytes)
Mammalia LOC469527 35
  • 99.6 (n)
  • 99.4 (a)
OR10R2 36
  • 99 (a)
(Canis familiaris)
Mammalia -- 36
  • 74 (a)
(Monodelphis domestica)
Mammalia OR10R2 36
  • 76 (a)
(Mus musculus)
Mammalia Olfr1406 36
  • 55 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101734876 35
  • 56.49 (n)
  • 53.44 (a)
Species with no ortholog for OR10R2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR10R2 Gene

Gene Tree for OR10R2 (if available)
Gene Tree for OR10R2 (if available)

Paralogs for OR10R2 Gene

(456) SIMAP similar genes for OR10R2 Gene using alignment to 1 proteins: Pseudogenes for OR10R2 Gene

genes like me logo Genes that share paralogs with OR10R2: view

Variants for OR10R2 Gene

Sequence variations from dbSNP and Humsavar for OR10R2 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs3820678 - 158,480,448(+) GTAGC(A/G)CCAAC reference, missense
rs6679056 - 158,480,524(+) TAACG(A/G)ATTTG reference, missense
rs1418843 - 158,480,592(+) CTTAT(C/T)TCTGC reference, missense
rs6666585 -- 158,480,622(+) AGATT(C/T)CCTCA reference, missense
rs11264977 -- 158,478,062(+) AGGAC(G/T)CCCTA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR10R2 Gene

Variant ID Type Subtype PubMed ID
dgv393n71 CNV Gain 21882294

Variation tolerance for OR10R2 Gene

Residual Variation Intolerance Score: 95.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 21.91; 99.36% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for OR10R2 Gene

Disorders for OR10R2 Gene

Relevant External Links for OR10R2

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for OR10R2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR10R2 Gene

Publications for OR10R2 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 67
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3
  3. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3

Products for OR10R2 Gene

Sources for OR10R2 Gene