Free for academic non-profit institutions. Other users need a Commercial license

Aliases for OR10Q1 Gene

Aliases for OR10Q1 Gene

  • Olfactory Receptor Family 10 Subfamily Q Member 1 2 3 5
  • Olfactory Receptor OR11-233 3 4
  • Olfactory Receptor, Family 10, Subfamily Q, Member 1 2
  • Olfactory Receptor 10Q1 3
  • OR11-233 3

External Ids for OR10Q1 Gene

Previous GeneCards Identifiers for OR10Q1 Gene

  • GC11U990579
  • GC11M057772
  • GC11M057751
  • GC11M057995

Summaries for OR10Q1 Gene

Entrez Gene Summary for OR10Q1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR10Q1 Gene

OR10Q1 (Olfactory Receptor Family 10 Subfamily Q Member 1) is a Protein Coding gene. Among its related pathways are Olfactory Signaling Pathway and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and odorant binding. An important paralog of this gene is OR10V1.

UniProtKB/Swiss-Prot for OR10Q1 Gene

  • Odorant receptor.

Gene Wiki entry for OR10Q1 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR10Q1 Gene

Genomics for OR10Q1 Gene

Regulatory Elements for OR10Q1 Gene

Enhancers for OR10Q1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11G057946 0.4 FANTOM5 11.4 +282.5 282484 0.0 RFX1 OR10W1 OR10Q1 OR9Q2 OR5B2 OR9Q1 OR5B12 MED19 OR5B3 OR1S1 OR9I1
GH11G058632 0.3 FANTOM5 7.8 -403.3 -403323 0.1 OR5B12 OR1S1 OR5B3 OR10W1 OR10Q1 OR5B2 OR9Q2 OR1S2 ENSG00000280010 ENSG00000197254
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around OR10Q1 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR10Q1 Gene

Chromosome:
11
Start:
58,227,882 bp from pter
End:
58,228,918 bp from pter
Size:
1,037 bases
Orientation:
Minus strand

Genomic View for OR10Q1 Gene

Genes around OR10Q1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR10Q1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR10Q1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR10Q1 Gene

Proteins for OR10Q1 Gene

  • Protein details for OR10Q1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGQ4-O10Q1_HUMAN
    Recommended name:
    Olfactory receptor 10Q1
    Protein Accession:
    Q8NGQ4
    Secondary Accessions:
    • Q6IFG4

    Protein attributes for OR10Q1 Gene

    Size:
    319 amino acids
    Molecular mass:
    35602 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR10Q1 Gene

Post-translational modifications for OR10Q1 Gene

  • Glycosylation at posLast=99
  • Modification sites at PhosphoSitePlus

Other Protein References for OR10Q1 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR10Q1 Gene

Domains & Families for OR10Q1 Gene

Gene Families for OR10Q1 Gene

Protein Domains for OR10Q1 Gene

Suggested Antigen Peptide Sequences for OR10Q1 Gene

Graphical View of Domain Structure for InterPro Entry

Q8NGQ4

UniProtKB/Swiss-Prot:

O10Q1_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR10Q1: view

Function for OR10Q1 Gene

Molecular function for OR10Q1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR10Q1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR10Q1: view

Phenotypes for OR10Q1 Gene

GenomeRNAi human phenotypes for OR10Q1:
genes like me logo Genes that share phenotypes with OR10Q1: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR10Q1 Gene

Localization for OR10Q1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR10Q1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OR10Q1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR10Q1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR10Q1: view

Pathways & Interactions for OR10Q1 Gene

genes like me logo Genes that share pathways with OR10Q1: view

Pathways by source for OR10Q1 Gene

Interacting Proteins for OR10Q1 Gene

Gene Ontology (GO) - Biological Process for OR10Q1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IEA --
GO:0050896 response to stimulus IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR10Q1: view

No data available for SIGNOR curated interactions for OR10Q1 Gene

Drugs & Compounds for OR10Q1 Gene

No Compound Related Data Available

Transcripts for OR10Q1 Gene

mRNA/cDNA for OR10Q1 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR10Q1 Gene

No ASD Table

Relevant External Links for OR10Q1 Gene

GeneLoc Exon Structure for
OR10Q1
ECgene alternative splicing isoforms for
OR10Q1

Expression for OR10Q1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OR10Q1 Gene

NURSA nuclear receptor signaling pathways regulating expression of OR10Q1 Gene:

OR10Q1

SOURCE GeneReport for Unigene cluster for OR10Q1 Gene:

Hs.553646
genes like me logo Genes that share expression patterns with OR10Q1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR10Q1 Gene

Orthologs for OR10Q1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR10Q1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC466599 34
  • 98.75 (n)
OR10Q1 35
  • 97 (a)
OneToOne
dog
(Canis familiaris)
Mammalia LOC483480 34
  • 86.58 (n)
-- 35
  • 84 (a)
OneToMany
-- 35
  • 82 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 83 (a)
OneToMany
-- 35
  • 76 (a)
OneToMany
-- 35
  • 74 (a)
OneToMany
-- 35
  • 74 (a)
OneToMany
-- 35
  • 72 (a)
OneToMany
-- 35
  • 72 (a)
OneToMany
-- 35
  • 68 (a)
OneToMany
cow
(Bos Taurus)
Mammalia OR10Q1 35
  • 82 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Or10q1 55 Olfr1494 34 16 35
  • 81.42 (n)
Or10q1b 55 Olfr1491 35
  • 81 (a)
OneToMany
Olfr1495 35
  • 73 (a)
OneToMany
Or7r1 55 Olfr1326
  • chrX:74,570,654-74,571,574
rat
(Rattus norvegicus)
Mammalia Olr374 34
  • 80.92 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 55 (a)
ManyToMany
Species where no ortholog for OR10Q1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR10Q1 Gene

ENSEMBL:
Gene Tree for OR10Q1 (if available)
TreeFam:
Gene Tree for OR10Q1 (if available)

Paralogs for OR10Q1 Gene

Paralogs for OR10Q1 Gene

(450) SIMAP similar genes for OR10Q1 Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for OR10Q1 Gene

genes like me logo Genes that share paralogs with OR10Q1: view

Variants for OR10Q1 Gene

Sequence variations from dbSNP and Humsavar for OR10Q1 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1000496803 -- 58,227,659(+) TAATA(C/T)GGCAA downstream-variant-500B
rs1002725719 -- 58,230,019(+) TATGT(A/T)CTCTT upstream-variant-2KB
rs1004729493 -- 58,227,785(+) TGAAT(A/T)GTGAA downstream-variant-500B
rs1006868909 -- 58,229,951(+) ACTTT(A/T)CATTC upstream-variant-2KB
rs1008230960 -- 58,228,959(+) AGTCT(C/T)GCTCT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR10Q1 Gene

Variant ID Type Subtype PubMed ID
nsv832165 CNV gain 17160897
nsv832166 CNV gain+loss 17160897

Variation tolerance for OR10Q1 Gene

Residual Variation Intolerance Score: 58.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 8.64; 86.31% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR10Q1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OR10Q1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR10Q1 Gene

Disorders for OR10Q1 Gene

Relevant External Links for OR10Q1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OR10Q1

No disorders were found for OR10Q1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR10Q1 Gene

Publications for OR10Q1 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 64
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for OR10Q1 Gene

Sources for OR10Q1 Gene

Content
Loading form....