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Aliases for OR10J5 Gene

Aliases for OR10J5 Gene

  • Olfactory Receptor, Family 10, Subfamily J, Member 5 2 3
  • Olfactory Receptor OR1-28 3 4
  • Olfactory Receptor 10J5 3
  • OR1-28 3

External Ids for OR10J5 Gene

Previous GeneCards Identifiers for OR10J5 Gene

  • GC01U990424
  • GC01M156722
  • GC01M156317
  • GC01M157771
  • GC01M157516

Summaries for OR10J5 Gene

Entrez Gene Summary for OR10J5 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR10J5 Gene

OR10J5 (Olfactory Receptor, Family 10, Subfamily J, Member 5) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include olfactory receptor activity and serotonin receptor activity. An important paralog of this gene is OR10X1.

UniProtKB/Swiss-Prot for OR10J5 Gene

  • Odorant receptor.

Gene Wiki entry for OR10J5 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR10J5 Gene

Genomics for OR10J5 Gene

Regulatory Elements for OR10J5 Gene

Genomic Location for OR10J5 Gene

Start:
159,535,078 bp from pter
End:
159,536,007 bp from pter
Size:
930 bases
Orientation:
Minus strand

Genomic View for OR10J5 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR10J5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR10J5 Gene

Proteins for OR10J5 Gene

  • Protein details for OR10J5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NHC4-O10J5_HUMAN
    Recommended name:
    Olfactory receptor 10J5
    Protein Accession:
    Q8NHC4
    Secondary Accessions:
    • B9EH35
    • Q6IFH2

    Protein attributes for OR10J5 Gene

    Size:
    309 amino acids
    Molecular mass:
    34401 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR10J5 Gene

Proteomics data for OR10J5 Gene at MOPED

Post-translational modifications for OR10J5 Gene

Other Protein References for OR10J5 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR10J5 Gene

Domains for OR10J5 Gene

Gene Families for OR10J5 Gene

HGNC:
  • OR10 :GPCR / Class A : Olfactory receptors

Protein Domains for OR10J5 Gene

Suggested Antigen Peptide Sequences for OR10J5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NHC4

UniProtKB/Swiss-Prot:

O10J5_HUMAN :
  • Q8NHC4
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR10J5: view

Function for OR10J5 Gene

Molecular function for OR10J5 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR10J5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR10J5: view
genes like me logo Genes that share phenotypes with OR10J5: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR10J5

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR10J5 Gene

Localization for OR10J5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR10J5 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR10J5 Gene COMPARTMENTS Subcellular localization image for OR10J5 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR10J5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR10J5: view

Pathways for OR10J5 Gene

genes like me logo Genes that share pathways with OR10J5: view

Pathways by source for OR10J5 Gene

Interacting Proteins for OR10J5 Gene

Gene Ontology (GO) - Biological Process for OR10J5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR10J5: view

Transcripts for OR10J5 Gene

mRNA/cDNA for OR10J5 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR10J5

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR10J5 Gene

No ASD Table

Relevant External Links for OR10J5 Gene

GeneLoc Exon Structure for
OR10J5
ECgene alternative splicing isoforms for
OR10J5

Expression for OR10J5 Gene

mRNA expression in normal human tissues for OR10J5 Gene

SOURCE GeneReport for Unigene cluster for OR10J5 Gene Hs.553587

genes like me logo Genes that share expressions with OR10J5: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for OR10J5 Gene

Orthologs for OR10J5 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR10J5 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia OR10J5 35
  • 84.97 (n)
  • 83.01 (a)
OR10J5 36
  • 83 (a)
OneToOne
dog
(Canis familiaris)
Mammalia OR10J5 35
  • 83.77 (n)
  • 85.39 (a)
OR10J5 36
  • 84 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Olfr16 35
  • 85.11 (n)
  • 87.38 (a)
Olfr16 16
Olfr16 36
  • 87 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia LOC469542 35
  • 99.24 (n)
  • 98.38 (a)
OR10J5 36
  • 98 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Olr1576 35
  • 85.01 (n)
  • 87.06 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 47 (a)
ManyToMany
Species with no ortholog for OR10J5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR10J5 Gene

ENSEMBL:
Gene Tree for OR10J5 (if available)
TreeFam:
Gene Tree for OR10J5 (if available)

Paralogs for OR10J5 Gene

Selected SIMAP similar genes for OR10J5 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for OR10J5 Gene

genes like me logo Genes that share paralogs with OR10J5: view

Variants for OR10J5 Gene

Sequence variations from dbSNP and Humsavar for OR10J5 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs756407 -- 159,537,630(+) TATTT(C/T)GACAT upstream-variant-2KB
rs756408 -- 159,537,172(+) TTTAT(C/T)TCCTT upstream-variant-2KB
rs1584250 -- 159,537,884(+) TAGTG(C/T)TGCAA upstream-variant-2KB
rs4656837 -- 159,535,507(+) CAGAA(C/T)GGCAA synonymous-codon, reference
rs10624793 -- 159,536,434(+) TTTGC(-/AA)AAAAA upstream-variant-2KB

Relevant External Links for OR10J5 Gene

HapMap Linkage Disequilibrium report
OR10J5
Human Gene Mutation Database (HGMD)
OR10J5

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for OR10J5 Gene

Disorders for OR10J5 Gene

Relevant External Links for OR10J5

Genetic Association Database (GAD)
OR10J5

No disorders were found for OR10J5 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for OR10J5 Gene

Publications for OR10J5 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  2. Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. (PMID: 17903294) Yang Q. … O'Donnell C.J. (BMC Med. Genet. 2007) 3 48
  3. Genome-wide association and population genetic analysis of C-reactive protein in African American and Hispanic American women. (PMID: 22939635) Reiner A.P. … Tang H. (Am. J. Hum. Genet. 2012) 3
  4. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie A.G. … Butte N.F. (PLoS ONE 2012) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for OR10J5 Gene

Sources for OR10J5 Gene

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