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Aliases for OR10J3 Gene

Aliases for OR10J3 Gene

  • Olfactory Receptor Family 10 Subfamily J Member 3 2 3 5
  • OR10J3P 3 4
  • Olfactory Receptor, Family 10, Subfamily J, Member 3 Pseudogene 3
  • Olfactory Receptor, Family 10, Subfamily J, Member 3 2
  • Olfactory Receptor OR1-25 Pseudogene 3
  • Olfactory Receptor 10J3 3
  • OR1-25 3

External Ids for OR10J3 Gene

Previous HGNC Symbols for OR10J3 Gene

  • OR10J3P

Previous GeneCards Identifiers for OR10J3 Gene

  • GC01M156500
  • GC01M156062
  • GC01M156096
  • GC01M157550

Summaries for OR10J3 Gene

Entrez Gene Summary for OR10J3 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR10J3 Gene

OR10J3 (Olfactory Receptor Family 10 Subfamily J Member 3) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and transmembrane signaling receptor activity. An important paralog of this gene is OR10J1.

UniProtKB/Swiss-Prot for OR10J3 Gene

  • Odorant receptor.

Gene Wiki entry for OR10J3 Gene

Additional gene information for OR10J3 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR10J3 Gene

Genomics for OR10J3 Gene

Regulatory Elements for OR10J3 Gene

Enhancers for OR10J3 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01H159172 1 FANTOM5 Ensembl ENCODE 9 +141.6 141576 1 CTBP2 EBF1 EZH2 ACKR1 CADM3-AS1 AIM2 ENSG00000212161 OR10J3 CADM3 OR6N1 OR6K3 FCER1A OR6N2
GH01H159596 0.9 Ensembl ENCODE 9.5 -283.3 -283316 2 FOXA2 JUN CEBPB MAX RAD21 EP300 FOXA1 YY1 GATA3 JUND OR10J5 OR10J3 OR10J6P DUSP23 SLAMF9 APCS
GH01H159211 0.7 Ensembl 9.2 +103.3 103259 0 SCRT1 CTCF ZNF654 ARNT CEBPB TRIM22 REST CEBPG RAD21 CC2D1A CADM3 AIM2 OR10J2P FCER1A OR10J3 DUSP23 ACKR1 CADM3-AS1 MPTX1
GH01H159229 0.5 ENCODE 10.2 +84.8 84780 1 STAT1 HNF4A REST RCOR1 FCER1A CADM3-AS1 ACKR1 OR10J2P OR10J3 MPTX1
GH01H159345 0.4 FANTOM5 11.2 -30.9 -30906 0 ZBTB40 OR10J3 FCER1A OR10J2P OR10J7P
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around OR10J3 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR10J3 Gene

Chromosome:
1
Start:
159,313,670 bp from pter
End:
159,314,659 bp from pter
Size:
990 bases
Orientation:
Minus strand

Genomic View for OR10J3 Gene

Genes around OR10J3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR10J3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR10J3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR10J3 Gene

Proteins for OR10J3 Gene

  • Protein details for OR10J3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5JRS4-O10J3_HUMAN
    Recommended name:
    Olfactory receptor 10J3
    Protein Accession:
    Q5JRS4

    Protein attributes for OR10J3 Gene

    Size:
    329 amino acids
    Molecular mass:
    36549 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR10J3 Gene

Post-translational modifications for OR10J3 Gene

  • Glycosylation at Asn5
  • Modification sites at PhosphoSitePlus

Other Protein References for OR10J3 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR10J3 Gene

Domains & Families for OR10J3 Gene

Gene Families for OR10J3 Gene

HGNC:
Human Protein Atlas (HPA):
  • G-protein coupled receptors
  • Predicted membrane proteins

Protein Domains for OR10J3 Gene

Suggested Antigen Peptide Sequences for OR10J3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q5JRS4

UniProtKB/Swiss-Prot:

O10J3_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR10J3: view

Function for OR10J3 Gene

Molecular function for OR10J3 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Phenotypes From GWAS Catalog for OR10J3 Gene

Gene Ontology (GO) - Molecular Function for OR10J3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004888 transmembrane signaling receptor activity IBA --
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR10J3: view

Phenotypes for OR10J3 Gene

genes like me logo Genes that share phenotypes with OR10J3: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for OR10J3
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR10J3 Gene

Localization for OR10J3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR10J3 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OR10J3 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR10J3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR10J3: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for OR10J3 Gene

Pathways & Interactions for OR10J3 Gene

genes like me logo Genes that share pathways with OR10J3: view

Pathways by source for OR10J3 Gene

Interacting Proteins for OR10J3 Gene

Gene Ontology (GO) - Biological Process for OR10J3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IEA --
GO:0050896 response to stimulus IEA --
GO:0050907 detection of chemical stimulus involved in sensory perception IBA --
genes like me logo Genes that share ontologies with OR10J3: view

No data available for SIGNOR curated interactions for OR10J3 Gene

Drugs & Compounds for OR10J3 Gene

No Compound Related Data Available

Transcripts for OR10J3 Gene

mRNA/cDNA for OR10J3 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for OR10J3
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for OR10J3 Gene

No ASD Table

Relevant External Links for OR10J3 Gene

GeneLoc Exon Structure for
OR10J3
ECgene alternative splicing isoforms for
OR10J3

Expression for OR10J3 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OR10J3 Gene

mRNA differential expression in normal tissues according to GTEx for OR10J3 Gene

This gene is overexpressed in Liver (x9.3), Brain - Nucleus accumbens (basal ganglia) (x5.2), and Cervix - Endocervix (x4.8).

Protein differential expression in normal tissues from HIPED for OR10J3 Gene

This gene is overexpressed in Plasma (35.7) and Neutrophil (31.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for OR10J3 Gene



Protein tissue co-expression partners for OR10J3 Gene

NURSA nuclear receptor signaling pathways regulating expression of OR10J3 Gene:

OR10J3

SOURCE GeneReport for Unigene cluster for OR10J3 Gene:

Hs.553833
genes like me logo Genes that share expression patterns with OR10J3: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR10J3 Gene

Orthologs for OR10J3 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR10J3 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia LOC488624 33
  • 87.83 (n)
-- 34
  • 81 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Or10j3 52 Olfr218 33 16 34
  • 84.04 (n)
Or10j3b 52 Olfr1404 34
  • 75 (a)
ManyToMany
rat
(Rattus norvegicus)
Mammalia Olr1582 33
  • 83.8 (n)
cow
(Bos Taurus)
Mammalia OR10J3 33
  • 83.44 (n)
-- 34
  • 81 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia OR10J3 33
  • 76.44 (n)
oppossum
(Monodelphis domestica)
Mammalia -- 34
  • 73 (a)
OneToMany
Species where no ortholog for OR10J3 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR10J3 Gene

ENSEMBL:
Gene Tree for OR10J3 (if available)
TreeFam:
Gene Tree for OR10J3 (if available)

Paralogs for OR10J3 Gene

(449) SIMAP similar genes for OR10J3 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for OR10J3 Gene

genes like me logo Genes that share paralogs with OR10J3: view

Variants for OR10J3 Gene

Sequence variations from dbSNP and Humsavar for OR10J3 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1001328296 -- 159,315,402(+) TTAAG(C/T)CTTAA upstream-variant-2KB
rs1001383763 -- 159,315,704(+) ATGCA(C/T)TTAAA upstream-variant-2KB
rs1001602438 -- 159,315,905(+) ATCCA(C/T)TGTAC upstream-variant-2KB
rs1004617112 -- 159,314,973(+) CCTAG(A/T)GGTAT upstream-variant-2KB
rs1004690583 -- 159,314,670(+) TAGGT(A/C)TAGGT upstream-variant-2KB

Variation tolerance for OR10J3 Gene

Residual Variation Intolerance Score: 67.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.07; 75.29% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR10J3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OR10J3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for OR10J3 Gene

Disorders for OR10J3 Gene

Relevant External Links for OR10J3

Genetic Association Database (GAD)
OR10J3
Human Genome Epidemiology (HuGE) Navigator
OR10J3
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OR10J3

No disorders were found for OR10J3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR10J3 Gene

Publications for OR10J3 Gene

  1. Chemerin, a novel adipokine in the regulation of angiogenesis. (PMID: 20237162) Bozaoglu K … Jowett JB (The Journal of clinical endocrinology and metabolism 2010) 3 45 60
  2. Risk of meningioma and common variation in genes related to innate immunity. (PMID: 20406964) Rajaraman P … Inskip PD (Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010) 3 45 60
  3. Polymorphisms in innate immunity genes and risk of childhood leukemia. (PMID: 20438785) Han S … Kang D (Human immunology 2010) 3 45 60
  4. Candidate gene approach evaluates association between innate immunity genes and breast cancer risk in Korean women. (PMID: 19372141) Lee JY … Kang D (Carcinogenesis 2009) 3 45 60
  5. Genome-wide association with select biomarker traits in the Framingham Heart Study. (PMID: 17903293) Benjamin EJ … Vasan RS (BMC medical genetics 2007) 3 45 60

Products for OR10J3 Gene

Sources for OR10J3 Gene

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