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Aliases for OR10J3 Gene

Aliases for OR10J3 Gene

  • Olfactory Receptor Family 10 Subfamily J Member 3 2 3 5
  • OR10J3P 3 4
  • Olfactory Receptor, Family 10, Subfamily J, Member 3 Pseudogene 3
  • Olfactory Receptor, Family 10, Subfamily J, Member 3 2
  • Olfactory Receptor OR1-25 Pseudogene 3
  • OR1-25 3

External Ids for OR10J3 Gene

Previous HGNC Symbols for OR10J3 Gene

  • OR10J3P

Previous GeneCards Identifiers for OR10J3 Gene

  • GC01M156500
  • GC01M156062
  • GC01M156096
  • GC01M157550

Summaries for OR10J3 Gene

Entrez Gene Summary for OR10J3 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR10J3 Gene

OR10J3 (Olfactory Receptor Family 10 Subfamily J Member 3) is a Protein Coding gene. Among its related pathways are Olfactory Signaling Pathway and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and transmembrane signaling receptor activity. An important paralog of this gene is OR10H1.

UniProtKB/Swiss-Prot for OR10J3 Gene

  • Odorant receptor.

Gene Wiki entry for OR10J3 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR10J3 Gene

Genomics for OR10J3 Gene

Regulatory Elements for OR10J3 Gene

Enhancers for OR10J3 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around OR10J3 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR10J3 Gene

Chromosome:
1
Start:
159,313,670 bp from pter
End:
159,314,659 bp from pter
Size:
990 bases
Orientation:
Minus strand

Genomic View for OR10J3 Gene

Genes around OR10J3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR10J3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR10J3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR10J3 Gene

Proteins for OR10J3 Gene

  • Protein details for OR10J3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5JRS4-O10J3_HUMAN
    Recommended name:
    Olfactory receptor 10J3
    Protein Accession:
    Q5JRS4

    Protein attributes for OR10J3 Gene

    Size:
    329 amino acids
    Molecular mass:
    36549 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR10J3 Gene

Proteomics data for OR10J3 Gene at MOPED

Post-translational modifications for OR10J3 Gene

  • Glycosylation at Asn 5
  • Modification sites at PhosphoSitePlus

Other Protein References for OR10J3 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

Antibody Products

No data available for DME Specific Peptides for OR10J3 Gene

Domains & Families for OR10J3 Gene

Gene Families for OR10J3 Gene

Protein Domains for OR10J3 Gene

Suggested Antigen Peptide Sequences for OR10J3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q5JRS4

UniProtKB/Swiss-Prot:

O10J3_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR10J3: view

Function for OR10J3 Gene

Molecular function for OR10J3 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR10J3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
genes like me logo Genes that share ontologies with OR10J3: view

Phenotypes for OR10J3 Gene

genes like me logo Genes that share phenotypes with OR10J3: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR10J3 Gene

Localization for OR10J3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR10J3 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR10J3 Gene COMPARTMENTS Subcellular localization image for OR10J3 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR10J3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA,IBA --
genes like me logo Genes that share ontologies with OR10J3: view

Pathways & Interactions for OR10J3 Gene

genes like me logo Genes that share pathways with OR10J3: view

Pathways by source for OR10J3 Gene

Interacting Proteins for OR10J3 Gene

Gene Ontology (GO) - Biological Process for OR10J3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR10J3: view

No data available for SIGNOR curated interactions for OR10J3 Gene

Drugs & Compounds for OR10J3 Gene

No Compound Related Data Available

Transcripts for OR10J3 Gene

mRNA/cDNA for OR10J3 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR10J3 Gene

No ASD Table

Relevant External Links for OR10J3 Gene

GeneLoc Exon Structure for
OR10J3
ECgene alternative splicing isoforms for
OR10J3

Expression for OR10J3 Gene

mRNA expression in normal human tissues for OR10J3 Gene

mRNA differential expression in normal tissues according to GTEx for OR10J3 Gene

This gene is overexpressed in Liver (x9.3), Brain - Nucleus accumbens (basal ganglia) (x5.2), and Cervix - Endocervix (x4.8).

Protein differential expression in normal tissues from HIPED for OR10J3 Gene

This gene is overexpressed in Plasma (35.7) and Neutrophil (31.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for OR10J3 Gene



SOURCE GeneReport for Unigene cluster for OR10J3 Gene Hs.553833

genes like me logo Genes that share expression patterns with OR10J3: view

Protein tissue co-expression partners for OR10J3 Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for OR10J3 Gene

Orthologs for OR10J3 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR10J3 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia OR10J3 35
  • 83.44 (n)
  • 82.47 (a)
-- 36
  • 81 (a)
OneToMany
dog
(Canis familiaris)
Mammalia LOC488624 35
  • 87.83 (n)
  • 89.01 (a)
-- 36
  • 81 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Olfr218 35
  • 84.04 (n)
  • 86.97 (a)
Olfr218 16
Olfr1404 36
  • 75 (a)
ManyToMany
Olfr218 36
  • 80 (a)
ManyToMany
chimpanzee
(Pan troglodytes)
Mammalia OR10J3 35
  • 76.44 (n)
  • 72.08 (a)
rat
(Rattus norvegicus)
Mammalia Olr1582 35
  • 83.8 (n)
  • 87.32 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 73 (a)
OneToMany
Species with no ortholog for OR10J3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR10J3 Gene

ENSEMBL:
Gene Tree for OR10J3 (if available)
TreeFam:
Gene Tree for OR10J3 (if available)

Paralogs for OR10J3 Gene

(449) SIMAP similar genes for OR10J3 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for OR10J3 Gene

genes like me logo Genes that share paralogs with OR10J3: view

Variants for OR10J3 Gene

Sequence variations from dbSNP and Humsavar for OR10J3 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs11265165 - 159,313,956(+) TCTTC(C/T)GACCT reference, missense
rs7522607 -- 159,316,201(+) ACTTA(C/T)CTAAG upstream-variant-2KB
rs10489856 -- 159,316,455(+) ATTCA(C/T)TTAAT upstream-variant-2KB
rs12116594 -- 159,313,207(+) cacga(A/G)attct downstream-variant-500B
rs12116625 -- 159,313,288(+) tagta(A/C/G)agatg downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for OR10J3 Gene

Variant ID Type Subtype PubMed ID
dgv396n71 CNV Loss 21882294

Variation tolerance for OR10J3 Gene

Residual Variation Intolerance Score: 67.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.07; 75.29% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR10J3 Gene

HapMap Linkage Disequilibrium report
OR10J3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR10J3 Gene

Disorders for OR10J3 Gene

Relevant External Links for OR10J3

Genetic Association Database (GAD)
OR10J3
Human Genome Epidemiology (HuGE) Navigator
OR10J3
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OR10J3

No disorders were found for OR10J3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR10J3 Gene

Publications for OR10J3 Gene

  1. Polymorphisms in innate immunity genes and risk of childhood leukemia. (PMID: 20438785) Han S. … Kang D. (Hum. Immunol. 2010) 3 48 67
  2. Genome-wide association and population genetic analysis of C-reactive protein in African American and Hispanic American women. (PMID: 22939635) Reiner A.P. … Tang H. (Am. J. Hum. Genet. 2012) 3
  3. A genome-wide association study of plasma total IgE concentrations in the Framingham Heart Study. (PMID: 22075330) Granada M. … O'Connor G.T. (J. Allergy Clin. Immunol. 2012) 3
  4. Chemerin, a novel adipokine in the regulation of angiogenesis. (PMID: 20237162) Bozaoglu K. … Jowett J.B. (J. Clin. Endocrinol. Metab. 2010) 3
  5. Risk of meningioma and common variation in genes related to innate immunity. (PMID: 20406964) Rajaraman P. … Inskip P.D. (Cancer Epidemiol. Biomarkers Prev. 2010) 3

Products for OR10J3 Gene

Sources for OR10J3 Gene

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