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Aliases for OR10J3 Gene

Aliases for OR10J3 Gene

  • Olfactory Receptor, Family 10, Subfamily J, Member 3 2 3
  • OR10J3P 3 4
  • Olfactory Receptor, Family 10, Subfamily J, Member 3 Pseudogene 3
  • Olfactory Receptor OR1-25 Pseudogene 3
  • Olfactory Receptor 10J3 3
  • OR1-25 3

External Ids for OR10J3 Gene

Previous Symbols for OR10J3 Gene

  • OR10J3P

Summaries for OR10J3 Gene

Entrez Gene Summary for OR10J3 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR10J3 Gene

OR10J3 (Olfactory Receptor, Family 10, Subfamily J, Member 3) is a Protein Coding gene. Diseases associated with OR10J3 include childhood leukemia. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR10X1.

UniProtKB/Swiss-Prot for OR10J3 Gene

  • Odorant receptor.

Gene Wiki entry for OR10J3 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR10J3 Gene

Genomics for OR10J3 Gene

Genomic Location for OR10J3 Gene

Start:
159,313,670 bp from pter
End:
159,314,659 bp from pter
Size:
990 bases
Orientation:
Minus strand

Genomic View for OR10J3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR10J3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR10J3 Gene

Regulatory Elements for OR10J3 Gene

Proteins for OR10J3 Gene

  • Protein details for OR10J3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5JRS4-O10J3_HUMAN
    Recommended name:
    Olfactory receptor 10J3
    Protein Accession:
    Q5JRS4
    Secondary Accessions:

    Protein attributes for OR10J3 Gene

    Size:
    329 amino acids
    Molecular mass:
    36549 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR10J3 Gene

Proteomics data for OR10J3 Gene at MOPED

Post-translational modifications for OR10J3 Gene

Other Protein References for OR10J3 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR10J3 Gene

Domains for OR10J3 Gene

Gene Families for OR10J3 Gene

HGNC:
  • OR10 :GPCR / Class A : Olfactory receptors

Protein Domains for OR10J3 Gene

UniProtKB/Swiss-Prot:

O10J3_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q5JRS4
genes like me logo Genes that share domains with OR10J3: view

Function for OR10J3 Gene

Molecular function for OR10J3 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR10J3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004888 transmembrane signaling receptor activity IBA --
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR10J3: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR10J3 Gene

Localization for OR10J3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR10J3 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR10J3 Gene COMPARTMENTS Subcellular localization image for OR10J3 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR10J3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR10J3: view

Pathways for OR10J3 Gene

genes like me logo Genes that share pathways with OR10J3: view

Pathways by source for OR10J3 Gene

Interacting Proteins for OR10J3 Gene

Gene Ontology (GO) - Biological Process for OR10J3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0050907 detection of chemical stimulus involved in sensory perception IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR10J3: view

Transcripts for OR10J3 Gene

mRNA/cDNA for OR10J3 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR10J3 Gene

No ASD Table

Relevant External Links for OR10J3 Gene

GeneLoc Exon Structure for
OR10J3
ECgene alternative splicing isoforms for
OR10J3

Expression for OR10J3 Gene

mRNA expression in normal human tissues for OR10J3 Gene

mRNA differential expression in normal tissues according to GTEx for OR10J3 Gene

This gene is overexpressed in Liver (9.3), Brain - Nucleus accumbens (basal ganglia) (5.2), and Cervix - Endocervix (4.8).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for OR10J3 Gene

SOURCE GeneReport for Unigene cluster for OR10J3 Gene Hs.553833

genes like me logo Genes that share expressions with OR10J3: view

Orthologs for OR10J3 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR10J3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia OR10J3 36
  • 76.44 (n)
  • 72.08 (a)
cow
(Bos Taurus)
Mammalia -- 37
  • 81 (a)
OneToMany
OR10J3 36
  • 83.44 (n)
  • 82.47 (a)
dog
(Canis familiaris)
Mammalia -- 37
  • 81 (a)
OneToMany
LOC488624 36
  • 87.83 (n)
  • 89.01 (a)
mouse
(Mus musculus)
Mammalia Olfr1404 16
Olfr1404 37
  • 75 (a)
ManyToMany
Olfr218 36
  • 84.04 (n)
  • 86.97 (a)
Olfr218 37
  • 80 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 73 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Olr1582 36
  • 83.8 (n)
  • 87.32 (a)
Species with no ortholog for OR10J3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR10J3 Gene

ENSEMBL:
Gene Tree for OR10J3 (if available)
TreeFam:
Gene Tree for OR10J3 (if available)

Paralogs for OR10J3 Gene

Selected SIMAP similar genes for OR10J3 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for OR10J3 Gene

genes like me logo Genes that share paralogs with OR10J3: view

Variants for OR10J3 Gene

Sequence variations from dbSNP and Humsavar for OR10J3 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs7522607 -- 159,316,201(+) ACTTA(C/T)CTAAG upstream-variant-2KB
rs10489856 -- 159,316,455(+) ATTCA(C/T)TTAAT upstream-variant-2KB
rs11265165 - 159,313,956(+) TCTTC(C/T)GACCT reference, missense
rs12116594 -- 159,313,207(+) cacga(A/G)attct downstream-variant-500B
rs12116625 -- 159,313,288(+) tagta(A/C/G)agatg downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for OR10J3 Gene

Variant ID Type Subtype PubMed ID
dgv396n71 CNV Loss 21882294

Relevant External Links for OR10J3 Gene

HapMap Linkage Disequilibrium report
OR10J3

Disorders for OR10J3 Gene

(1) MalaCards Diseases for OR10J3 Gene

Search for OR10J3 Gene in MalaCards »

Relevant External Links for OR10J3

Genetic Association Database (GAD)
OR10J3
Human Genome Epidemiology (HuGE) Navigator
OR10J3
genes like me logo Genes that share disorders with OR10J3: view

No data available for UniProtKB/Swiss-Prot for OR10J3 Gene

Publications for OR10J3 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  2. Genome-wide association with select biomarker traits in the Framingham Heart Study. (PMID: 17903293) Benjamin E.J. … Vasan R.S. (BMC Med. Genet. 2007) 3 49
  3. Candidate gene approach evaluates association between innate immunity genes and breast cancer risk in Korean women. (PMID: 19372141) Lee J.Y. … Kang D. (Carcinogenesis 2009) 3 49
  4. Chemerin, a novel adipokine in the regulation of angiogenesis. (PMID: 20237162) Bozaoglu K. … Jowett J.B. (J. Clin. Endocrinol. Metab. 2010) 3 49
  5. Risk of meningioma and common variation in genes related to innate immunity. (PMID: 20406964) Rajaraman P. … Inskip P.D. (Cancer Epidemiol. Biomarkers Prev. 2010) 3 49

Products for OR10J3 Gene

  • antibodies-online peptides for OR10J3
  • antibodies-online antibodies for OR10J3
  • antibodies-online kits for OR10J3

Sources for OR10J3 Gene

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