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Aliases for OR10J3 Gene

Aliases for OR10J3 Gene

  • Olfactory Receptor Family 10 Subfamily J Member 3 2 3 5
  • OR10J3P 3 4
  • Olfactory Receptor, Family 10, Subfamily J, Member 3 Pseudogene 3
  • Olfactory Receptor, Family 10, Subfamily J, Member 3 2
  • Olfactory Receptor OR1-25 Pseudogene 3
  • Olfactory Receptor 10J3 3
  • OR1-25 3

External Ids for OR10J3 Gene

Previous HGNC Symbols for OR10J3 Gene

  • OR10J3P

Previous GeneCards Identifiers for OR10J3 Gene

  • GC01M156500
  • GC01M156062
  • GC01M156096
  • GC01M157550

Summaries for OR10J3 Gene

Entrez Gene Summary for OR10J3 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR10J3 Gene

OR10J3 (Olfactory Receptor Family 10 Subfamily J Member 3) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and transmembrane signaling receptor activity. An important paralog of this gene is OR10J1.

UniProtKB/Swiss-Prot for OR10J3 Gene

  • Odorant receptor.

Gene Wiki entry for OR10J3 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR10J3 Gene

Genomics for OR10J3 Gene

Regulatory Elements for OR10J3 Gene

Enhancers for OR10J3 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F159291 0.7 Ensembl 11.7 +22.8 22759 0.6 ATF3 OR10J3 FCER1A
GH01F159345 0.9 FANTOM5 11.2 -30.9 -30906 0.0 ZBTB40 OR10J3 FCER1A OR10J2P OR10J7P
GH01F159229 0.2 ENCODE 10.2 +84.8 84780 1.1 STAT1 ZNF512 REST FCER1A CADM3-AS1 ACKR1 OR10J2P OR10J3 MPTX1
GH01F159427 0.5 ENCODE 10.2 -114.1 -114093 2.8 JUND MNT OR10J3 FCER1A OR10J2P ENSG00000228560 OR10J4 OR10J9P
GH01F159219 0.2 Ensembl 9.7 +95.6 95559 0.2 ATF1 SMARCA4 POLR2A RFXANK CADM3 AIM2 OR10J2P FCER1A OR10J3 ENSG00000212161 CADM3-AS1 MPTX1
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around OR10J3 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR10J3 Gene

159,313,670 bp from pter
159,314,659 bp from pter
990 bases
Minus strand

Genomic View for OR10J3 Gene

Genes around OR10J3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR10J3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR10J3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR10J3 Gene

Proteins for OR10J3 Gene

  • Protein details for OR10J3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 10J3
    Protein Accession:

    Protein attributes for OR10J3 Gene

    329 amino acids
    Molecular mass:
    36549 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR10J3 Gene

Post-translational modifications for OR10J3 Gene

  • Glycosylation at Asn 5
  • Modification sites at PhosphoSitePlus

Other Protein References for OR10J3 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR10J3 Gene

Domains & Families for OR10J3 Gene

Gene Families for OR10J3 Gene

Protein Domains for OR10J3 Gene

Suggested Antigen Peptide Sequences for OR10J3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR10J3: view

Function for OR10J3 Gene

Molecular function for OR10J3 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR10J3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004888 transmembrane signaling receptor activity IBA --
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR10J3: view

Phenotypes for OR10J3 Gene

genes like me logo Genes that share phenotypes with OR10J3: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR10J3 Gene

Localization for OR10J3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR10J3 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR10J3 Gene COMPARTMENTS Subcellular localization image for OR10J3 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR10J3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR10J3: view

Pathways & Interactions for OR10J3 Gene

genes like me logo Genes that share pathways with OR10J3: view

Pathways by source for OR10J3 Gene

Interacting Proteins for OR10J3 Gene

Gene Ontology (GO) - Biological Process for OR10J3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IEA --
GO:0050896 response to stimulus IEA --
GO:0050907 detection of chemical stimulus involved in sensory perception IBA --
genes like me logo Genes that share ontologies with OR10J3: view

No data available for SIGNOR curated interactions for OR10J3 Gene

Transcripts for OR10J3 Gene

mRNA/cDNA for OR10J3 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR10J3 Gene

No ASD Table

Relevant External Links for OR10J3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR10J3 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for OR10J3 Gene

mRNA differential expression in normal tissues according to GTEx for OR10J3 Gene

This gene is overexpressed in Liver (x9.3), Brain - Nucleus accumbens (basal ganglia) (x5.2), and Cervix - Endocervix (x4.8).

Protein differential expression in normal tissues from HIPED for OR10J3 Gene

This gene is overexpressed in Plasma (35.7) and Neutrophil (31.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for OR10J3 Gene

Protein tissue co-expression partners for OR10J3 Gene

NURSA nuclear receptor signaling pathways regulating expression of OR10J3 Gene:


SOURCE GeneReport for Unigene cluster for OR10J3 Gene:

genes like me logo Genes that share expression patterns with OR10J3: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for OR10J3 Gene

Orthologs for OR10J3 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR10J3 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia LOC488624 34
  • 87.83 (n)
-- 35
  • 81 (a)
(Mus musculus)
Mammalia Or10j3 55 Olfr218 34 16 35
  • 84.04 (n)
Or10j3b 55 Olfr1404 35
  • 75 (a)
(Rattus norvegicus)
Mammalia Olr1582 34
  • 83.8 (n)
(Bos Taurus)
Mammalia OR10J3 34
  • 83.44 (n)
-- 35
  • 81 (a)
(Pan troglodytes)
Mammalia OR10J3 34
  • 76.44 (n)
(Monodelphis domestica)
Mammalia -- 35
  • 73 (a)
Species where no ortholog for OR10J3 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR10J3 Gene

Gene Tree for OR10J3 (if available)
Gene Tree for OR10J3 (if available)

Paralogs for OR10J3 Gene

(449) SIMAP similar genes for OR10J3 Gene using alignment to 1 proteins: Pseudogenes for OR10J3 Gene

genes like me logo Genes that share paralogs with OR10J3: view

Variants for OR10J3 Gene

Sequence variations from dbSNP and Humsavar for OR10J3 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs10489856 -- 159,316,455(+) ATTCA(C/T)TTAAT upstream-variant-2KB
rs11265165 -- 159,313,956(+) TCTTC(C/T)GACCT reference, missense
rs113853686 -- 159,315,406(+) GCCTT(-/A)AAAAA upstream-variant-2KB
rs116605700 -- 159,316,035(+) ATACA(C/T)TCCTG upstream-variant-2KB
rs116822906 -- 159,314,708(+) CATAT(C/G)ATGAG upstream-variant-2KB

Variation tolerance for OR10J3 Gene

Residual Variation Intolerance Score: 67.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.07; 75.29% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR10J3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for OR10J3 Gene

Disorders for OR10J3 Gene

Relevant External Links for OR10J3

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for OR10J3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR10J3 Gene

Publications for OR10J3 Gene

  1. Chemerin, a novel adipokine in the regulation of angiogenesis. (PMID: 20237162) Bozaoglu K. … Jowett J.B. (J. Clin. Endocrinol. Metab. 2010) 3 46 64
  2. Risk of meningioma and common variation in genes related to innate immunity. (PMID: 20406964) Rajaraman P. … Inskip P.D. (Cancer Epidemiol. Biomarkers Prev. 2010) 3 46 64
  3. Polymorphisms in innate immunity genes and risk of childhood leukemia. (PMID: 20438785) Han S. … Kang D. (Hum. Immunol. 2010) 3 46 64
  4. Candidate gene approach evaluates association between innate immunity genes and breast cancer risk in Korean women. (PMID: 19372141) Lee J.Y. … Kang D. (Carcinogenesis 2009) 3 46 64
  5. Genome-wide association with select biomarker traits in the Framingham Heart Study. (PMID: 17903293) Benjamin E.J. … Vasan R.S. (BMC Med. Genet. 2007) 3 46 64

Products for OR10J3 Gene

Sources for OR10J3 Gene

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