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Aliases for OR10J1 Gene

Aliases for OR10J1 Gene

  • Olfactory Receptor Family 10 Subfamily J Member 1 2 3 5
  • Olfactory Receptor-Like Protein HGMP07J 3 4
  • Olfactory Receptor OR1-26 3 4
  • Olfactory Receptor, Family 10, Subfamily J, Member 1 2
  • Olfactory Receptor 10J1 3
  • HSHGMP07J 3
  • HGMP07J 3

External Ids for OR10J1 Gene

Previous GeneCards Identifiers for OR10J1 Gene

  • GC01P157201
  • GC01P155141
  • GC01P156187
  • GC01P156626
  • GC01P156619
  • GC01P156222
  • GC01P157669
  • GC01P157590
  • GC01P157676
  • GC01P159320
  • GC01P159409

Summaries for OR10J1 Gene

Entrez Gene Summary for OR10J1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR10J1 Gene

OR10J1 (Olfactory Receptor Family 10 Subfamily J Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and odorant binding. An important paralog of this gene is OR10J5.

UniProtKB/Swiss-Prot for OR10J1 Gene

  • Odorant receptor.

Gene Wiki entry for OR10J1 Gene

Additional gene information for OR10J1 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR10J1 Gene

Genomics for OR10J1 Gene

Regulatory Elements for OR10J1 Gene

Enhancers for OR10J1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01H159141 0.9 FANTOM5 Ensembl 3 -255.5 -255506 0 TBP MXI1 JUND POLR3A ZBTB48 POLR2A FOS PRDM10 TCF7L2 OR6K3 OR6N1 FCER1A CADM3 ACKR1 CADM3-AS1 OR6N2 OR10J5 AIM2 OR10J1
GH01H158972 0.5 FANTOM5 1.7 -424.5 -424463 0 CTCF SMC3 RAD21 FCER1A OR6N1 OR6K3 OR10Z1 DUSP23 OR10R2 OR10X1 OR6N2 PYHIN1 OR6P1
GH01H159682 0.3 FANTOM5 2.8 +285.4 285446 0 FCER1A CRP OR10J5 OR10J1 CRPP1 ENSG00000276632
GH01H159300 0.3 FANTOM5 2.3 -97.2 -97183 0 OR10J1 OR10J3 FCER1A
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around OR10J1 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR10J1 Gene

Chromosome:
1
Start:
159,397,494 bp from pter
End:
159,443,078 bp from pter
Size:
45,585 bases
Orientation:
Plus strand

Genomic View for OR10J1 Gene

Genes around OR10J1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR10J1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR10J1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR10J1 Gene

Proteins for OR10J1 Gene

  • Protein details for OR10J1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P30954-O10J1_HUMAN
    Recommended name:
    Olfactory receptor 10J1
    Protein Accession:
    P30954
    Secondary Accessions:
    • Q2M1M8
    • Q5VSV1
    • Q6IET5
    • Q96R56

    Protein attributes for OR10J1 Gene

    Size:
    320 amino acids
    Molecular mass:
    35925 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR10J1 Gene

Post-translational modifications for OR10J1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for OR10J1 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR10J1 Gene

Domains & Families for OR10J1 Gene

Gene Families for OR10J1 Gene

HGNC:
Human Protein Atlas (HPA):
  • G-protein coupled receptors
  • Predicted membrane proteins

Protein Domains for OR10J1 Gene

Suggested Antigen Peptide Sequences for OR10J1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P30954

UniProtKB/Swiss-Prot:

O10J1_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR10J1: view

Function for OR10J1 Gene

Molecular function for OR10J1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Phenotypes From GWAS Catalog for OR10J1 Gene

Gene Ontology (GO) - Molecular Function for OR10J1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004888 transmembrane signaling receptor activity IBA --
GO:0004930 G-protein coupled receptor activity TAS,IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR10J1: view
genes like me logo Genes that share phenotypes with OR10J1: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for OR10J1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR10J1 Gene

Localization for OR10J1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR10J1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OR10J1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR10J1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane TAS 1370859
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR10J1: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for OR10J1 Gene

Pathways & Interactions for OR10J1 Gene

genes like me logo Genes that share pathways with OR10J1: view

Pathways by source for OR10J1 Gene

1 BioSystems pathway for OR10J1 Gene
1 KEGG pathway for OR10J1 Gene

Interacting Proteins for OR10J1 Gene

Gene Ontology (GO) - Biological Process for OR10J1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway TAS,IBA --
GO:0007338 single fertilization TAS 1370859
GO:0007606 sensory perception of chemical stimulus TAS 1370859
GO:0007608 sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR10J1: view

No data available for SIGNOR curated interactions for OR10J1 Gene

Drugs & Compounds for OR10J1 Gene

No Compound Related Data Available

Transcripts for OR10J1 Gene

mRNA/cDNA for OR10J1 Gene

(3) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(2) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR10J1 Gene

Olfactory receptor, family 10, subfamily J, member 1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for OR10J1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for OR10J1 Gene

No ASD Table

Relevant External Links for OR10J1 Gene

GeneLoc Exon Structure for
OR10J1
ECgene alternative splicing isoforms for
OR10J1

Expression for OR10J1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OR10J1 Gene

mRNA differential expression in normal tissues according to GTEx for OR10J1 Gene

This gene is overexpressed in Testis (x52.4).

NURSA nuclear receptor signaling pathways regulating expression of OR10J1 Gene:

OR10J1

SOURCE GeneReport for Unigene cluster for OR10J1 Gene:

Hs.532661

Evidence on tissue expression from TISSUES for OR10J1 Gene

  • Nervous system(4)
genes like me logo Genes that share expression patterns with OR10J1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR10J1 Gene

Orthologs for OR10J1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR10J1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia OR10J1 34
  • 87 (a)
OneToOne
LOC530601 33
  • 82.09 (n)
chimpanzee
(Pan troglodytes)
Mammalia LOC469539 33
  • 81.23 (n)
dog
(Canis familiaris)
Mammalia LOC100683336 33
  • 78.53 (n)
OR10J1 34
  • 78 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC681470 33
  • 77.63 (n)
mouse
(Mus musculus)
Mammalia Olfr418-ps1 33 34
  • 77.49 (n)
Olfr418 16
oppossum
(Monodelphis domestica)
Mammalia OR10J1 34
  • 77 (a)
OneToOne
Species where no ortholog for OR10J1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR10J1 Gene

ENSEMBL:
Gene Tree for OR10J1 (if available)
TreeFam:
Gene Tree for OR10J1 (if available)

Paralogs for OR10J1 Gene

(458) SIMAP similar genes for OR10J1 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for OR10J1 Gene

genes like me logo Genes that share paralogs with OR10J1: view

Variants for OR10J1 Gene

Sequence variations from dbSNP and Humsavar for OR10J1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000011035 -- 159,437,602(+) TTGAA(G/T)CAAAA intron-variant
rs1000011958 -- 159,417,861(+) TGATA(C/T)GGACA intron-variant
rs1000041590 -- 159,417,629(+) TTAAC(A/C)AGTCT intron-variant
rs1000110691 -- 159,413,143(+) GATAC(C/T)ACCTC intron-variant
rs1000312225 -- 159,410,061(+) TCATG(A/G)TGGAT intron-variant

Variation tolerance for OR10J1 Gene

Residual Variation Intolerance Score: 89% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.90; 83.77% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR10J1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OR10J1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for OR10J1 Gene

Disorders for OR10J1 Gene

Relevant External Links for OR10J1

Genetic Association Database (GAD)
OR10J1
Human Genome Epidemiology (HuGE) Navigator
OR10J1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OR10J1

No disorders were found for OR10J1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR10J1 Gene

Publications for OR10J1 Gene

  1. Expression of members of the putative olfactory receptor gene family in mammalian germ cells. (PMID: 1370859) Parmentier M … Perret J (Nature 1992) 2 3 4 60
  2. Chemerin, a novel adipokine in the regulation of angiogenesis. (PMID: 20237162) Bozaoglu K … Jowett JB (The Journal of clinical endocrinology and metabolism 2010) 3 45 60
  3. Genome-wide association with select biomarker traits in the Framingham Heart Study. (PMID: 17903293) Benjamin EJ … Vasan RS (BMC medical genetics 2007) 3 45 60
  4. Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. (PMID: 17903294) Yang Q … O'Donnell CJ (BMC medical genetics 2007) 3 45 60
  5. The human olfactory receptor gene family. (PMID: 14983052) Malnic B … Buck LB (Proceedings of the National Academy of Sciences of the United States of America 2004) 3 4 60

Products for OR10J1 Gene

Sources for OR10J1 Gene

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