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Aliases for OR10H4 Gene

Aliases for OR10H4 Gene

  • Olfactory Receptor, Family 10, Subfamily H, Member 4 2 3
  • Olfactory Receptor OR19-28 3 4
  • Olfactory Receptor 10H4 3
  • OR19-28 3

External Ids for OR10H4 Gene

Previous GeneCards Identifiers for OR10H4 Gene

  • GC19U990264
  • GC19P015921
  • GC19P015922
  • GC19P016059

Summaries for OR10H4 Gene

Entrez Gene Summary for OR10H4 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR10H4 Gene

OR10H4 (Olfactory Receptor, Family 10, Subfamily H, Member 4) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include olfactory receptor activity and serotonin receptor activity. An important paralog of this gene is OR10X1.

UniProtKB/Swiss-Prot for OR10H4 Gene

  • Odorant receptor.

Gene Wiki entry for OR10H4 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR10H4 Gene

Genomics for OR10H4 Gene

Regulatory Elements for OR10H4 Gene

Genomic Location for OR10H4 Gene

15,949,008 bp from pter
15,949,958 bp from pter
951 bases
Plus strand

Genomic View for OR10H4 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR10H4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR10H4 Gene

Proteins for OR10H4 Gene

  • Protein details for OR10H4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 10H4
    Protein Accession:
    Secondary Accessions:
    • Q6IFJ2
    • Q96R57

    Protein attributes for OR10H4 Gene

    316 amino acids
    Molecular mass:
    35765 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR10H4 Gene

Proteomics data for OR10H4 Gene at MOPED

Post-translational modifications for OR10H4 Gene

  • Glycosylation at Asn5
  • Modification sites at PhosphoSitePlus

Other Protein References for OR10H4 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

Antibody Products

No data available for DME Specific Peptides for OR10H4 Gene

Domains for OR10H4 Gene

Gene Families for OR10H4 Gene

  • OR10 :GPCR / Class A : Olfactory receptors

Protein Domains for OR10H4 Gene

Suggested Antigen Peptide Sequences for OR10H4 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q8NGA5
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR10H4: view

Function for OR10H4 Gene

Molecular function for OR10H4 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR10H4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR10H4: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR10H4

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR10H4 Gene

Localization for OR10H4 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR10H4 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR10H4 Gene COMPARTMENTS Subcellular localization image for OR10H4 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR10H4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR10H4: view

Pathways for OR10H4 Gene

genes like me logo Genes that share pathways with OR10H4: view

Pathways by source for OR10H4 Gene

Interacting Proteins for OR10H4 Gene

Gene Ontology (GO) - Biological Process for OR10H4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0008150 biological_process ND --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR10H4: view

Transcripts for OR10H4 Gene

mRNA/cDNA for OR10H4 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR10H4

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR10H4 Gene

No ASD Table

Relevant External Links for OR10H4 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR10H4 Gene

mRNA expression in normal human tissues for OR10H4 Gene

SOURCE GeneReport for Unigene cluster for OR10H4 Gene Hs.553579

genes like me logo Genes that share expressions with OR10H4: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for OR10H4 Gene

Orthologs for OR10H4 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR10H4 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia LOC506323 35
  • 85.45 (n)
  • 82.08 (a)
-- 36
  • 82 (a)
-- 36
  • 80 (a)
-- 36
  • 80 (a)
-- 36
  • 81 (a)
-- 36
  • 80 (a)
(Pan troglodytes)
Mammalia LOC468757 35
  • 98.63 (n)
  • 97.15 (a)
OR10H4 36
  • 97 (a)
(Canis familiaris)
Mammalia -- 36
  • 45 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 67 (a)
-- 36
  • 67 (a)
-- 36
  • 62 (a)
(Mus musculus)
Mammalia Olfr63 36
  • 76 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 62 (a)
Species with no ortholog for OR10H4:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR10H4 Gene

Gene Tree for OR10H4 (if available)
Gene Tree for OR10H4 (if available)

Paralogs for OR10H4 Gene

Selected SIMAP similar genes for OR10H4 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR10H4: view

Variants for OR10H4 Gene

Sequence variations from dbSNP and Humsavar for OR10H4 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1594685 -- 15,950,017(+) GTAAG(G/T)GTTCA downstream-variant-500B
rs7247641 -- 15,947,993(+) GAAAT(C/G)AAGAT upstream-variant-2KB
rs7251780 -- 15,947,721(+) AAAAA(A/T)TTTTT upstream-variant-2KB
rs9305071 -- 15,948,330(+) AAGGA(A/G)CTCTG upstream-variant-2KB
rs9305072 -- 15,948,514(+) AAATG(C/T)ACCAT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR10H4 Gene

Variant ID Type Subtype PubMed ID
esv2718244 CNV Deletion 23290073
nsv833766 CNV Loss 17160897

Relevant External Links for OR10H4 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR10H4 Gene

Disorders for OR10H4 Gene

No disorders were found for OR10H4 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for OR10H4 Gene

Publications for OR10H4 Gene

  1. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4

Products for OR10H4 Gene

Sources for OR10H4 Gene

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