Free for academic non-profit institutions. Other users need a Commercial license

Aliases for OR10H2 Gene

Aliases for OR10H2 Gene

  • Olfactory Receptor, Family 10, Subfamily H, Member 2 2 3
  • Olfactory Receptor OR19-23 4

External Ids for OR10H2 Gene

Previous GeneCards Identifiers for OR10H2 Gene

  • GC19M016330
  • GC19P016232
  • GC19P015684
  • GC19P015699
  • GC19P015838

Summaries for OR10H2 Gene

Entrez Gene Summary for OR10H2 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR10H2 Gene

OR10H2 (Olfactory Receptor, Family 10, Subfamily H, Member 2) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include olfactory receptor activity and serotonin receptor activity. An important paralog of this gene is OR10X1.

UniProtKB/Swiss-Prot for OR10H2 Gene

  • Odorant receptor.

Gene Wiki entry for OR10H2 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR10H2 Gene

Genomics for OR10H2 Gene

Regulatory Elements for OR10H2 Gene

Genomic Location for OR10H2 Gene

Start:
15,728,020 bp from pter
End:
15,729,060 bp from pter
Size:
1,041 bases
Orientation:
Plus strand

Genomic View for OR10H2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR10H2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR10H2 Gene

Proteins for OR10H2 Gene

  • Protein details for OR10H2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O60403-O10H2_HUMAN
    Recommended name:
    Olfactory receptor 10H2
    Protein Accession:
    O60403
    Secondary Accessions:
    • Q6IFQ1
    • Q96R58

    Protein attributes for OR10H2 Gene

    Size:
    315 amino acids
    Molecular mass:
    34663 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR10H2 Gene

Proteomics data for OR10H2 Gene at MOPED

Post-translational modifications for OR10H2 Gene

Other Protein References for OR10H2 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR10H2 Gene

Domains for OR10H2 Gene

Gene Families for OR10H2 Gene

HGNC:
  • OR10 :GPCR / Class A : Olfactory receptors

Protein Domains for OR10H2 Gene

Suggested Antigen Peptide Sequences for OR10H2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

O60403

UniProtKB/Swiss-Prot:

O10H2_HUMAN :
  • O60403
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR10H2: view

Function for OR10H2 Gene

Molecular function for OR10H2 Gene

GENATLAS Biochemistry: olfactory receptor,family 10,subfamily H,member 2,G protein coupled receptor superfamily
UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR10H2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR10H2: view

miRNA for OR10H2 Gene

miRTarBase miRNAs that target OR10H2

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for OR10H2 Gene

Localization for OR10H2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR10H2 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR10H2 Gene COMPARTMENTS Subcellular localization image for OR10H2 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR10H2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR10H2: view

Pathways for OR10H2 Gene

genes like me logo Genes that share pathways with OR10H2: view

Pathways by source for OR10H2 Gene

1 BioSystems pathway for OR10H2 Gene
1 KEGG pathway for OR10H2 Gene

Interacting Proteins for OR10H2 Gene

Gene Ontology (GO) - Biological Process for OR10H2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR10H2: view

Transcripts for OR10H2 Gene

mRNA/cDNA for OR10H2 Gene

(4) Additional mRNA sequences :
(7) Selected AceView cDNA sequences:
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR10H2 Gene

Olfactory receptor, family 10, subfamily H, member 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for OR10H2 Gene

No ASD Table

Relevant External Links for OR10H2 Gene

GeneLoc Exon Structure for
OR10H2
ECgene alternative splicing isoforms for
OR10H2

Expression for OR10H2 Gene

mRNA expression in normal human tissues for OR10H2 Gene

SOURCE GeneReport for Unigene cluster for OR10H2 Gene Hs.247694

genes like me logo Genes that share expressions with OR10H2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for OR10H2 Gene

Orthologs for OR10H2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR10H2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC468755 35
  • 98.31 (n)
  • 97.14 (a)
OR10H2 36
  • 97 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 83 (a)
ManyToMany
-- 36
  • 81 (a)
ManyToMany
-- 36
  • 81 (a)
ManyToMany
-- 36
  • 83 (a)
ManyToMany
LOC532441 35
  • 85.78 (n)
  • 82.74 (a)
OR10H1 36
  • 83 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 84 (a)
ManyToMany
-- 36
  • 83 (a)
ManyToMany
-- 36
  • 80 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Gm4461 16
Gm4461 36
  • 81 (a)
ManyToMany
Olfr239 36
  • 84 (a)
ManyToMany
Olfr55 36
  • 83 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 73 (a)
ManyToMany
-- 36
  • 74 (a)
ManyToMany
-- 36
  • 70 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 68 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Olr1091 35
  • 82.73 (n)
  • 85.48 (a)
Species with no ortholog for OR10H2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR10H2 Gene

ENSEMBL:
Gene Tree for OR10H2 (if available)
TreeFam:
Gene Tree for OR10H2 (if available)

Paralogs for OR10H2 Gene

Selected SIMAP similar genes for OR10H2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR10H2: view

Variants for OR10H2 Gene

Sequence variations from dbSNP and Humsavar for OR10H2 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1806931 - 15,728,555(-) CATGG(A/G)ATCCA reference, missense
rs2003905 -- 15,728,358(-) AAGCT(A/G)AAGGA reference, synonymous-codon
rs2067083 -- 15,728,271(-) ATGAT(A/G)GCCAC reference, synonymous-codon
rs2107452 -- 15,727,384(+) CCCTA(C/T)GTCCT upstream-variant-2KB
rs2285955 -- 15,728,157(+) TTCAC(A/G)CTGCT synonymous-codon, reference

Structural Variations from Database of Genomic Variants (DGV) for OR10H2 Gene

Variant ID Type Subtype PubMed ID
nsv911139 CNV Gain 21882294
nsv470128 CNV Gain 18288195
dgv137e55 CNV Gain 17911159
dgv1059e1 CNV Complex 17122850
nsv526168 CNV Gain 19592680
esv3260 OTHER Inversion 18987735

Relevant External Links for OR10H2 Gene

HapMap Linkage Disequilibrium report
OR10H2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR10H2 Gene

Disorders for OR10H2 Gene

No disorders were found for OR10H2 Gene.

No data available for UniProtKB/Swiss-Prot for OR10H2 Gene

Publications for OR10H2 Gene

  1. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  3. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for OR10H2 Gene

  • antibodies-online proteins for OR10H2
  • antibodies-online antibodies for OR10H2
  • antibodies-online kits for OR10H2

Sources for OR10H2 Gene

Back to Top

Content