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Aliases for OR10H1 Gene

Aliases for OR10H1 Gene

  • Olfactory Receptor Family 10 Subfamily H Member 1 2 3 5
  • Olfactory Receptor, Family 10, Subfamily H, Member 1 2
  • Olfactory Receptor OR19-27 4

External Ids for OR10H1 Gene

Previous GeneCards Identifiers for OR10H1 Gene

  • GC19M016403
  • GC19M015763
  • GC19M015779
  • GC19M015780
  • GC19M015917

Summaries for OR10H1 Gene

Entrez Gene Summary for OR10H1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR10H1 Gene

OR10H1 (Olfactory Receptor Family 10 Subfamily H Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR10H5.

UniProtKB/Swiss-Prot for OR10H1 Gene

  • Odorant receptor.

Gene Wiki entry for OR10H1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR10H1 Gene

Genomics for OR10H1 Gene

Regulatory Elements for OR10H1 Gene

Enhancers for OR10H1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19F015679 0.9 ENCODE 11.3 +128.1 128070 3.2 PKNOX1 ARID4B ZNF48 RAD21 RARA YY1 FOS CREM EGR2 THAP11 CYP4F24P CYP4F12 OR10H1 CYP4F11 RNU6-782P GC19M015702
GH19F015812 0.7 ENCODE 0.8 -3.5 -3507 0.2 CTCF MTA2 REST RAD21 GATA3 ZNF512 SMC3 ZNF143 CUX1 DEK CYP4F24P OR10H1 ZNF861P
GH19F015810 0.7 ENCODE 0.8 -1.8 -1827 0.2 CTCF JUN REST BRCA1 RAD21 RFX5 JUND ATF3 SCRT2 SMC3 OR10H1 ZNF861P
GH19F015815 0.5 ENCODE 0.4 -6.8 -6787 0.1 ZBTB33 FOS FOSL2 NR2F2 OR10H1 ZNF861P
GH19F015820 0.3 FANTOM5 0.4 -12.2 -12206 0.1 OR10H4 OR10H5 CYP4F11 OR10H3 OR10H2 AKAP8 RASAL3 ZNF861P OR10H1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around OR10H1 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR10H1 Gene

15,806,957 bp from pter
15,808,759 bp from pter
1,803 bases
Minus strand

Genomic View for OR10H1 Gene

Genes around OR10H1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR10H1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR10H1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR10H1 Gene

Proteins for OR10H1 Gene

  • Protein details for OR10H1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 10H1
    Protein Accession:
    Secondary Accessions:
    • Q6IFQ2
    • Q96R59

    Protein attributes for OR10H1 Gene

    318 amino acids
    Molecular mass:
    35254 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR10H1 Gene

Post-translational modifications for OR10H1 Gene

  • Glycosylation at Asn 5
  • Modification sites at PhosphoSitePlus

Other Protein References for OR10H1 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR10H1 Gene

Domains & Families for OR10H1 Gene

Gene Families for OR10H1 Gene

Protein Domains for OR10H1 Gene

Suggested Antigen Peptide Sequences for OR10H1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR10H1: view

Function for OR10H1 Gene

Molecular function for OR10H1 Gene

GENATLAS Biochemistry:
olfactory receptor,family 10,subfamily H,member 1,G protein coupled receptor superfamily
UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR10H1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
GO:0004993 G-protein coupled serotonin receptor activity IBA --
GO:0030594 neurotransmitter receptor activity IBA --
genes like me logo Genes that share ontologies with OR10H1: view
genes like me logo Genes that share phenotypes with OR10H1: view

Animal Model Products

miRNA for OR10H1 Gene

miRTarBase miRNAs that target OR10H1

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for OR10H1 Gene

Localization for OR10H1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR10H1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OR10H1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR10H1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane IBA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
GO:0030425 dendrite IBA --
genes like me logo Genes that share ontologies with OR10H1: view

Pathways & Interactions for OR10H1 Gene

genes like me logo Genes that share pathways with OR10H1: view

Pathways by source for OR10H1 Gene

1 BioSystems pathway for OR10H1 Gene
1 KEGG pathway for OR10H1 Gene

Gene Ontology (GO) - Biological Process for OR10H1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0007192 adenylate cyclase-activating serotonin receptor signaling pathway IBA --
GO:0007268 chemical synaptic transmission IBA --
GO:0007608 sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR10H1: view

No data available for SIGNOR curated interactions for OR10H1 Gene

Transcripts for OR10H1 Gene

mRNA/cDNA for OR10H1 Gene

(2) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(10) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR10H1 Gene

Olfactory receptor, family 10, subfamily H, member 1:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR10H1 Gene

No ASD Table

Relevant External Links for OR10H1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR10H1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for OR10H1 Gene

mRNA differential expression in normal tissues according to GTEx for OR10H1 Gene

This gene is overexpressed in Bladder (x30.9), Testis (x10.5), and Prostate (x4.6).

NURSA nuclear receptor signaling pathways regulating expression of OR10H1 Gene:


SOURCE GeneReport for Unigene cluster for OR10H1 Gene:

genes like me logo Genes that share expression patterns with OR10H1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for OR10H1 Gene

Orthologs for OR10H1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR10H1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia OR10H1 34 35
  • 88.43 (n)
-- 35
  • 85 (a)
-- 35
  • 85 (a)
-- 35
  • 85 (a)
-- 35
  • 83 (a)
(Canis familiaris)
Mammalia cOR10H13 34
  • 87.79 (n)
-- 35
  • 87 (a)
-- 35
  • 85 (a)
-- 35
  • 82 (a)
(Mus musculus)
Mammalia Or10h1b 55 Olfr55 16 35
  • 85 (a)
Or10h1 55 Olfr239 34 35
  • 83.97 (n)
Gm4461 35
  • 83 (a)
(Rattus norvegicus)
Mammalia Olr1095 34
  • 84.09 (n)
(Monodelphis domestica)
Mammalia -- 35
  • 77 (a)
-- 35
  • 76 (a)
-- 35
  • 70 (a)
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 71 (a)
Species where no ortholog for OR10H1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR10H1 Gene

Gene Tree for OR10H1 (if available)
Gene Tree for OR10H1 (if available)

Paralogs for OR10H1 Gene

(446) SIMAP similar genes for OR10H1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR10H1: view

Variants for OR10H1 Gene

Sequence variations from dbSNP and Humsavar for OR10H1 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs10417639 -- 15,808,478(+) GCCCA(A/G)GAGTT intron-variant, upstream-variant-2KB
rs112265265 -- 15,810,174(+) CCTGT(G/T)GTCCC upstream-variant-2KB
rs112289393 -- 15,808,854(+) AAAAA(-/T)AAAAA upstream-variant-2KB
rs113437022 -- 15,806,686(+) TATAA(A/G)TGTGA downstream-variant-500B
rs113542714 -- 15,809,275(+) TTATT(-/TATTTATTTATG)TATTT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR10H1 Gene

Variant ID Type Subtype PubMed ID
esv2660137 CNV deletion 23128226
esv2671181 CNV deletion 23128226
esv2718244 CNV deletion 23290073
esv3334671 CNV duplication 20981092
nsv1060711 CNV gain 25217958
nsv1064684 CNV gain 25217958
nsv1133007 OTHER inversion 24896259
nsv833766 CNV loss 17160897

Variation tolerance for OR10H1 Gene

Residual Variation Intolerance Score: 91.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 9.79; 89.50% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR10H1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR10H1 Gene

Disorders for OR10H1 Gene

Relevant External Links for OR10H1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for OR10H1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR10H1 Gene

Publications for OR10H1 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 64
  2. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3 4 64
  3. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4 64
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for OR10H1 Gene

Sources for OR10H1 Gene

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