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Aliases for OR10H1 Gene

Aliases for OR10H1 Gene

  • Olfactory Receptor Family 10 Subfamily H Member 1 2 3 5
  • Olfactory Receptor, Family 10, Subfamily H, Member 1 2
  • Olfactory Receptor OR19-27 4

External Ids for OR10H1 Gene

Previous GeneCards Identifiers for OR10H1 Gene

  • GC19M016403
  • GC19M015763
  • GC19M015779
  • GC19M015780
  • GC19M015917

Summaries for OR10H1 Gene

Entrez Gene Summary for OR10H1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR10H1 Gene

OR10H1 (Olfactory Receptor Family 10 Subfamily H Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR10X1.

UniProtKB/Swiss-Prot for OR10H1 Gene

  • Odorant receptor.

Gene Wiki entry for OR10H1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR10H1 Gene

Genomics for OR10H1 Gene

Regulatory Elements for OR10H1 Gene

Enhancers for OR10H1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around OR10H1 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR10H1 Gene

15,806,957 bp from pter
15,808,759 bp from pter
1,803 bases
Minus strand

Genomic View for OR10H1 Gene

Genes around OR10H1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR10H1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR10H1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR10H1 Gene

Proteins for OR10H1 Gene

  • Protein details for OR10H1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 10H1
    Protein Accession:
    Secondary Accessions:
    • Q6IFQ2
    • Q96R59

    Protein attributes for OR10H1 Gene

    318 amino acids
    Molecular mass:
    35254 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR10H1 Gene

Proteomics data for OR10H1 Gene at MOPED

Post-translational modifications for OR10H1 Gene

  • Glycosylation at Asn 5
  • Modification sites at PhosphoSitePlus

Other Protein References for OR10H1 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

Antibody Products

  • Santa Cruz Biotechnology (SCBT) Antibodies for OR10H1

No data available for DME Specific Peptides for OR10H1 Gene

Domains & Families for OR10H1 Gene

Gene Families for OR10H1 Gene

Protein Domains for OR10H1 Gene

Suggested Antigen Peptide Sequences for OR10H1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR10H1: view

Function for OR10H1 Gene

Molecular function for OR10H1 Gene

GENATLAS Biochemistry:
olfactory receptor,family 10,subfamily H,member 1,G protein coupled receptor superfamily
UniProtKB/Swiss-Prot Function:
Odorant receptor.

Phenotypes for OR10H1 Gene

genes like me logo Genes that share phenotypes with OR10H1: view

Animal Model Products

CRISPR Products

miRNA for OR10H1 Gene

miRTarBase miRNAs that target OR10H1

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for OR10H1 Gene

Localization for OR10H1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR10H1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR10H1 Gene COMPARTMENTS Subcellular localization image for OR10H1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR10H1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR10H1: view

Pathways & Interactions for OR10H1 Gene

genes like me logo Genes that share pathways with OR10H1: view

Pathways by source for OR10H1 Gene

1 BioSystems pathway for OR10H1 Gene
1 KEGG pathway for OR10H1 Gene

Interacting Proteins for OR10H1 Gene

Gene Ontology (GO) - Biological Process for OR10H1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR10H1: view

No data available for SIGNOR curated interactions for OR10H1 Gene

Drugs & Compounds for OR10H1 Gene

No Compound Related Data Available

Transcripts for OR10H1 Gene

mRNA/cDNA for OR10H1 Gene

(2) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(10) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR10H1 Gene

Olfactory receptor, family 10, subfamily H, member 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for OR10H1 Gene

No ASD Table

Relevant External Links for OR10H1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR10H1 Gene

mRNA expression in normal human tissues for OR10H1 Gene

mRNA differential expression in normal tissues according to GTEx for OR10H1 Gene

This gene is overexpressed in Bladder (x30.9), Testis (x10.5), and Prostate (x4.6).

SOURCE GeneReport for Unigene cluster for OR10H1 Gene Hs.533925

genes like me logo Genes that share expression patterns with OR10H1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for OR10H1 Gene

Orthologs for OR10H1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR10H1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia OR10H1 35
  • 88.43 (n)
  • 89.49 (a)
-- 36
  • 85 (a)
-- 36
  • 85 (a)
-- 36
  • 85 (a)
-- 36
  • 83 (a)
OR10H1 36
  • 89 (a)
(Canis familiaris)
Mammalia cOR10H13 35
  • 87.79 (n)
  • 87.58 (a)
-- 36
  • 82 (a)
-- 36
  • 85 (a)
-- 36
  • 87 (a)
(Mus musculus)
Mammalia Olfr239 35
  • 83.97 (n)
  • 86.31 (a)
Olfr55 16
Gm4461 36
  • 83 (a)
Olfr239 36
  • 86 (a)
Olfr55 36
  • 85 (a)
(Rattus norvegicus)
Mammalia Olr1095 35
  • 84.09 (n)
  • 86.77 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 76 (a)
-- 36
  • 77 (a)
-- 36
  • 70 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 71 (a)
Species with no ortholog for OR10H1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR10H1 Gene

Gene Tree for OR10H1 (if available)
Gene Tree for OR10H1 (if available)

Paralogs for OR10H1 Gene

(446) SIMAP similar genes for OR10H1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR10H1: view

Variants for OR10H1 Gene

Sequence variations from dbSNP and Humsavar for OR10H1 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs4808383 - 15,807,992(+) GAAGC(C/G)GACGA reference, missense
rs4808382 - 15,807,844(+) AGAGG(A/C/G/T)CGCAC reference, missense
rs1859298 - 15,807,513(+) AAATG(C/G)TGGAT reference, missense
rs8102640 -- 15,810,289(+) actcc(G/T)tctca upstream-variant-2KB
rs8103631 -- 15,807,623(+) GCCCC(A/G)CGGGC reference, missense

Structural Variations from Database of Genomic Variants (DGV) for OR10H1 Gene

Variant ID Type Subtype PubMed ID
nsv911139 CNV Gain 21882294
esv2718244 CNV Deletion 23290073
nsv833766 CNV Loss 17160897
esv2671181 CNV Deletion 23128226
esv2660137 CNV Deletion 23128226

Variation tolerance for OR10H1 Gene

Residual Variation Intolerance Score: 91.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 9.79; 89.50% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for OR10H1 Gene

Disorders for OR10H1 Gene

Relevant External Links for OR10H1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for OR10H1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR10H1 Gene

Publications for OR10H1 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 67
  2. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3
  3. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for OR10H1 Gene

Sources for OR10H1 Gene