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Aliases for OR10G7 Gene

Aliases for OR10G7 Gene

  • Olfactory Receptor Family 10 Subfamily G Member 7 2 3 5
  • Olfactory Receptor, Family 10, Subfamily G, Member 7 2 3
  • Olfactory Receptor OR11-283 3 4
  • OR11-283 3

External Ids for OR10G7 Gene

Previous GeneCards Identifiers for OR10G7 Gene

  • GC11U990343
  • GC11M123447
  • GC11M123413
  • GC11M123908

Summaries for OR10G7 Gene

Entrez Gene Summary for OR10G7 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR10G7 Gene

OR10G7 (Olfactory Receptor Family 10 Subfamily G Member 7) is a Protein Coding gene. Among its related pathways are Olfactory Signaling Pathway and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR10D3.

UniProtKB/Swiss-Prot for OR10G7 Gene

  • Odorant receptor.

Gene Wiki entry for OR10G7 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR10G7 Gene

Genomics for OR10G7 Gene

Regulatory Elements for OR10G7 Gene

Enhancers for OR10G7 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around OR10G7 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR10G7 Gene

Chromosome:
11
Start:
124,038,066 bp from pter
End:
124,039,010 bp from pter
Size:
945 bases
Orientation:
Minus strand

Genomic View for OR10G7 Gene

Genes around OR10G7 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR10G7 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR10G7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR10G7 Gene

Proteins for OR10G7 Gene

  • Protein details for OR10G7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGN6-O10G7_HUMAN
    Recommended name:
    Olfactory receptor 10G7
    Protein Accession:
    Q8NGN6
    Secondary Accessions:
    • Q6IFE8

    Protein attributes for OR10G7 Gene

    Size:
    311 amino acids
    Molecular mass:
    34517 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR10G7 Gene

Proteomics data for OR10G7 Gene at MOPED

Post-translational modifications for OR10G7 Gene

  • Glycosylation at Asn 3
  • Modification sites at PhosphoSitePlus

Other Protein References for OR10G7 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR10G7 Gene

Domains & Families for OR10G7 Gene

Gene Families for OR10G7 Gene

Protein Domains for OR10G7 Gene

Suggested Antigen Peptide Sequences for OR10G7 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NGN6

UniProtKB/Swiss-Prot:

O10G7_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR10G7: view

Function for OR10G7 Gene

Molecular function for OR10G7 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR10G7 Gene

Localization for OR10G7 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR10G7 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR10G7 Gene COMPARTMENTS Subcellular localization image for OR10G7 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR10G7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA,IBA --
genes like me logo Genes that share ontologies with OR10G7: view

Pathways & Interactions for OR10G7 Gene

genes like me logo Genes that share pathways with OR10G7: view

Pathways by source for OR10G7 Gene

Interacting Proteins for OR10G7 Gene

Gene Ontology (GO) - Biological Process for OR10G7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR10G7: view

No data available for SIGNOR curated interactions for OR10G7 Gene

Drugs & Compounds for OR10G7 Gene

No Compound Related Data Available

Transcripts for OR10G7 Gene

mRNA/cDNA for OR10G7 Gene

(1) REFSEQ mRNAs :
(2) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR10G7 Gene

No ASD Table

Relevant External Links for OR10G7 Gene

GeneLoc Exon Structure for
OR10G7
ECgene alternative splicing isoforms for
OR10G7

Expression for OR10G7 Gene

mRNA expression in normal human tissues for OR10G7 Gene

SOURCE GeneReport for Unigene cluster for OR10G7 Gene Hs.553761

genes like me logo Genes that share expression patterns with OR10G7: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for OR10G7 Gene

Orthologs for OR10G7 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR10G7 Gene

Organism Taxonomy Gene Similarity Type Details
mouse
(Mus musculus)
Mammalia Olfr978 35
  • 84.89 (n)
  • 86.82 (a)
Olfr978 16
Olfr978 36
  • 87 (a)
ManyToMany
Olfr979 36
  • 85 (a)
ManyToMany
Olfr980 36
  • 84 (a)
ManyToMany
chimpanzee
(Pan troglodytes)
Mammalia LOC737779 35
  • 97.96 (n)
  • 95.82 (a)
OR10G7 36
  • 96 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 79 (a)
ManyToMany
-- 36
  • 79 (a)
ManyToMany
-- 36
  • 79 (a)
ManyToMany
-- 36
  • 78 (a)
ManyToMany
-- 36
  • 78 (a)
ManyToMany
-- 36
  • 79 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 85 (a)
ManyToMany
-- 36
  • 85 (a)
ManyToMany
-- 36
  • 85 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 77 (a)
ManyToMany
-- 36
  • 70 (a)
ManyToMany
-- 36
  • 68 (a)
ManyToMany
-- 36
  • 70 (a)
ManyToMany
-- 36
  • 70 (a)
ManyToMany
-- 36
  • 70 (a)
ManyToMany
-- 36
  • 71 (a)
ManyToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100485341 35
  • 58.03 (n)
  • 53.11 (a)
Species with no ortholog for OR10G7:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR10G7 Gene

ENSEMBL:
Gene Tree for OR10G7 (if available)
TreeFam:
Gene Tree for OR10G7 (if available)

Paralogs for OR10G7 Gene

Paralogs for OR10G7 Gene

(450) SIMAP similar genes for OR10G7 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for OR10G7 Gene

genes like me logo Genes that share paralogs with OR10G7: view

Variants for OR10G7 Gene

Sequence variations from dbSNP and Humsavar for OR10G7 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs3894197 - 124,038,988(-) CGCCA(C/G)CCTAC reference, missense
rs513591 - 124,038,595(-) GATGA(C/G)TGGGC reference, missense
rs11827843 - 124,038,964(+) GGCCC(A/G)TGAGG reference, missense
rs3894198 - 124,038,949(-) CCATG(C/T)CCCAG reference, missense
rs3894199 - 124,038,943(-) CCCAG(C/G)GCTGG reference, missense

Structural Variations from Database of Genomic Variants (DGV) for OR10G7 Gene

Variant ID Type Subtype PubMed ID
dgv82n21 CNV Gain 19592680
nsv898435 CNV Gain 21882294
esv2665842 CNV Deletion 23128226

Variation tolerance for OR10G7 Gene

Residual Variation Intolerance Score: 98.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.45; 64.09% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR10G7 Gene

HapMap Linkage Disequilibrium report
OR10G7
Human Gene Mutation Database (HGMD)
OR10G7

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR10G7 Gene

Disorders for OR10G7 Gene

Relevant External Links for OR10G7

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OR10G7

No disorders were found for OR10G7 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR10G7 Gene

Publications for OR10G7 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 67
  2. Genome-wide association study identifies candidate genes for male fertility traits in humans. (PMID: 22633400) Kosova G. … Ober C. (Am. J. Hum. Genet. 2012) 3

Products for OR10G7 Gene

Sources for OR10G7 Gene

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