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Aliases for OR10G4 Gene

Aliases for OR10G4 Gene

  • Olfactory Receptor Family 10 Subfamily G Member 4 2 3 5
  • Olfactory Receptor, Family 10, Subfamily G, Member 4 2 3
  • Olfactory Receptor OR11-278 3 4
  • OR11-278 3

External Ids for OR10G4 Gene

Previous GeneCards Identifiers for OR10G4 Gene

  • GC11U990358
  • GC11P123424
  • GC11P123391
  • GC11P123886

Summaries for OR10G4 Gene

Entrez Gene Summary for OR10G4 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR10G4 Gene

OR10G4 (Olfactory Receptor Family 10 Subfamily G Member 4) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR10D3.

UniProtKB/Swiss-Prot for OR10G4 Gene

  • Odorant receptor.

Gene Wiki entry for OR10G4 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR10G4 Gene

Genomics for OR10G4 Gene

Regulatory Elements for OR10G4 Gene

Enhancers for OR10G4 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around OR10G4 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR10G4 Gene

124,015,575 bp from pter
124,016,510 bp from pter
936 bases
Plus strand

Genomic View for OR10G4 Gene

Genes around OR10G4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR10G4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR10G4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR10G4 Gene

Proteins for OR10G4 Gene

  • Protein details for OR10G4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 10G4
    Protein Accession:
    Secondary Accessions:
    • Q6IEW0

    Protein attributes for OR10G4 Gene

    311 amino acids
    Molecular mass:
    34569 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR10G4 Gene

Proteomics data for OR10G4 Gene at MOPED

Post-translational modifications for OR10G4 Gene

  • Glycosylation at Asn 3
  • Modification sites at PhosphoSitePlus

Other Protein References for OR10G4 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

Antibody Products

No data available for DME Specific Peptides for OR10G4 Gene

Domains & Families for OR10G4 Gene

Gene Families for OR10G4 Gene

Protein Domains for OR10G4 Gene

Suggested Antigen Peptide Sequences for OR10G4 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR10G4: view

Function for OR10G4 Gene

Molecular function for OR10G4 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR10G4 Gene

Localization for OR10G4 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR10G4 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR10G4 Gene COMPARTMENTS Subcellular localization image for OR10G4 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR10G4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA,IBA --
genes like me logo Genes that share ontologies with OR10G4: view

Pathways & Interactions for OR10G4 Gene

genes like me logo Genes that share pathways with OR10G4: view

Pathways by source for OR10G4 Gene

Interacting Proteins for OR10G4 Gene

Gene Ontology (GO) - Biological Process for OR10G4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR10G4: view

No data available for SIGNOR curated interactions for OR10G4 Gene

Drugs & Compounds for OR10G4 Gene

No Compound Related Data Available

Transcripts for OR10G4 Gene

mRNA/cDNA for OR10G4 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR10G4 Gene

No ASD Table

Relevant External Links for OR10G4 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR10G4 Gene

mRNA expression in normal human tissues for OR10G4 Gene

mRNA differential expression in normal tissues according to GTEx for OR10G4 Gene

This gene is overexpressed in Pancreas (x38.6), Testis (x7.5), and Colon - Transverse (x6.9).

Protein differential expression in normal tissues from HIPED for OR10G4 Gene

This gene is overexpressed in Lung (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for OR10G4 Gene

SOURCE GeneReport for Unigene cluster for OR10G4 Gene Hs.553760

genes like me logo Genes that share expression patterns with OR10G4: view

Protein tissue co-expression partners for OR10G4 Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for OR10G4 Gene

Orthologs for OR10G4 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR10G4 Gene

Organism Taxonomy Gene Similarity Type Details
(Mus musculus)
Mammalia Olfr980 35
  • 84.95 (n)
  • 85.48 (a)
Olfr980 16
Olfr978 36
  • 85 (a)
Olfr979 36
  • 86 (a)
Olfr980 36
  • 85 (a)
(Rattus norvegicus)
Mammalia Olr1335 35
  • 83.76 (n)
  • 84.52 (a)
(Bos Taurus)
Mammalia -- 36
  • 80 (a)
-- 36
  • 82 (a)
-- 36
  • 82 (a)
-- 36
  • 79 (a)
-- 36
  • 80 (a)
-- 36
  • 79 (a)
(Canis familiaris)
Mammalia -- 36
  • 85 (a)
-- 36
  • 86 (a)
-- 36
  • 82 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 78 (a)
-- 36
  • 70 (a)
-- 36
  • 68 (a)
-- 36
  • 70 (a)
-- 36
  • 72 (a)
-- 36
  • 72 (a)
-- 36
  • 71 (a)
Species with no ortholog for OR10G4:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR10G4 Gene

Gene Tree for OR10G4 (if available)
Gene Tree for OR10G4 (if available)

Paralogs for OR10G4 Gene

Paralogs for OR10G4 Gene

(449) SIMAP similar genes for OR10G4 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR10G4: view

Variants for OR10G4 Gene

Sequence variations from dbSNP and Humsavar for OR10G4 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs4084209 - 124,016,158(-) CCATC(A/T)CGTTG reference, missense
rs4936880 - 124,016,277(+) GGCGC(A/G/T)GAGCC reference, missense
rs547068 - 124,015,645(-) AGAGG(A/G)GGGCG reference, missense
rs1893766 - 124,015,974(-) CATCA(C/T)GCTGG reference, missense
rs1893764 - 124,016,115(-) GGGCG(A/G)TGCGT reference, missense

Structural Variations from Database of Genomic Variants (DGV) for OR10G4 Gene

Variant ID Type Subtype PubMed ID
dgv82n21 CNV Gain 19592680
nsv898435 CNV Gain 21882294
esv2582148 CNV Deletion 19546169

Variation tolerance for OR10G4 Gene

Residual Variation Intolerance Score: 92.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 22.27; 99.41% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR10G4 Gene

Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR10G4 Gene

Disorders for OR10G4 Gene

Relevant External Links for OR10G4

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for OR10G4 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR10G4 Gene

Publications for OR10G4 Gene

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48 67
  2. The missense of smell: functional variability in the human odorant receptor repertoire. (PMID: 24316890) Mainland J.D. … Matsunami H. (Nat. Neurosci. 2014) 3
  3. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3

Products for OR10G4 Gene

Sources for OR10G4 Gene