OR10D3 Gene
protein-coding GIFtS: 33
GCID: GC11P124055
|
|
olfactory receptor, family 10, subfamily D, member 3 (non-functional)(Previous names: olfactory receptor, family 10, subfamily D, member 3 pseudogene...) (Previous symbol: OR10D3P)
| |
Aliases for OR10D3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Olfactory Receptor, Family 10, Subfamily D, Member 3 (Non-Functional)1 2 | | HTPCRX091 2 3 | | OR10D3P1 2 3 | | Olfactory Receptor, Family 10, Subfamily D, Member 3 Pseudogene1 | | Olfactory Receptor OR11-2933 |
Export aliases for OR10D3 gene to outside databases |
Summaries for OR10D3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for OR10D3: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers theperception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors(GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with manyneurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction ofodorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to theolfactory receptor genes and proteins for this organism is independent of other organisms. (provided by RefSeq, Jul2008) UniProtKB/Swiss-Prot: O10D3_HUMAN, Q8NH80Function: Odorant receptor (Potential)
|
Genomic Views for OR10D3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_033899.8
Regulatory elements: Search SABiosciences Regulatory transcription factor binding sites for OR10D3 Other transcription factors
Search SABiosciences Chromatin IP Primers for OR10D3
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OR10D3 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11q24.2 Ensembl cytogenetic band: 11q24.2 HGNC cytogenetic band: 11q24.2OR10D3 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11P124055: view genomic region
(about GC identifiers)
Start:
|
124,055,977 bp from pter |
End:
|
124,056,912 bp from pter |
Size:
|
936 bases |
Orientation:
|
plus strand |
|
Proteins for OR10D3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: O10D3_HUMAN, Q8NH80 (See
protein sequence)Recommended Name: Putative olfactory receptor 10D3 Size: 312 amino acids; 34812 Da
Subcellular location: Cell membrane; Multi-pass membrane protein (Potential)
Caution: Could be the product of a pseudogeneExplore the universe of human proteins at neXtProt for OR10D3: NX_Q8NH80
HORDE protein sequence for OR10D3 OR10D3 Protein expression data from MOPED and PaxDb: About this image 
ENSEMBL proteins: ENSP00000323895 Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005886 | plasma membrane |
IEA | -- | | GO:0016021 | integral to membrane |
IEA | -- |
OR10D3 for ontologies About GeneDecksing
OR10D3 Antibody Products: Assay Products for OR10D3: |
Protein
Domains / Families for OR10D3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
OR10D3 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8NH80ProtoNet protein and cluster: Q8NH80 1 Blocks protein family: IPB000725 Olfactory receptor signature
UniProtKB/Swiss-Prot: O10D3_HUMAN, Q8NH80Similarity: Belongs to the G-protein coupled receptor 1 family |
Function for OR10D3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: O10D3_HUMAN, Q8NH80Function: Odorant receptor (Potential)
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004930 | G-protein coupled receptor activity |
IEA | -- | | GO:0004984 | olfactory receptor activity |
IEA | -- |
OR10D3 for ontologies About GeneDecksing
|
Pathways & Interactions for OR10D3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for OR10D3
|
Drugs & Compounds for OR10D3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for OR10D3 Search CenterWatch for drugs/clinical trials and news about OR10D3 / O10D3 
|
Transcripts for OR10D3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| Unigene Cluster for OR10D3: Olfactory receptor, family 10, subfamily D, member 3 (non-functional) Hs.538726 [show with all ESTs]Unigene Representative Sequence: EG3576661 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000318666(uc001pzv.2)
Additional cDNA sequence: X64983.1 1 DOTS entry: DT.120739215 1 AceView cDNA sequence: X64983 GeneLoc Exon Structure
|
Expression for OR10D3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| OR10D3 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: GCTGTTAGGG
About this image See OR10D3 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for OR10D3
SOURCE GeneReport for Unigene cluster: Hs.538726 SABiosciences Custom PCR Arrays for OR10D3
Primer Products: |  | Browse OriGene genome-wide validated SYBR primer pairs Browse OriGene validated miRNA SYBR primer pairs
| |  | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat OR10D3 | |  | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OR10D3 | |  | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OR10D3 |
Orthologs for OR10D3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for OR10D3 (if available) TreeFam Gene Tree for OR10D3 (if available)  |
Paralogs for OR10D3 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for OR10D3 gene
- OR10S12 OR10G22 OR10G92 OR10G32 OR10G42 OR10G72 OR10G82
18/451 SIMAP similar genes for OR10D3 using alignment to 1 protein entry: O10D3_HUMAN(see all similar genes):OR10D4P OR10G2 OR10G7 OR10G9 OR10G4 OR2J4P OR10G8 OR4D2 OR10G3 OR2B6 OR4D1 OR4K2 OR4N5 OR4Q2 OR4Q3 OR5AR1 OR5B12 OR5B21
OR10D3 for paralogs About GeneDecksing
3 Pseudogenes.org Pseudogenes for OR10D3 PGOHUM00000257866 PGOHUM00000257867 PGOHUM00000257925
|
Genomic Variants for OR10D3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|  | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases for OR10D3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
OR10D3 for disorders About GeneDecksing
1 disease for OR10D3: About MalaCardsneuronitis Export disorders for OR10D3 gene to outside databases
|
Publications for OR10D3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for OR10D3 gene integrated from 9 sources: (articles sorted by number of sources associating them with OR10D3) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Expression of members of the putative olfactory receptor gene family in mammalian germ cells. (PubMed id 1370859)1, 2, 3 Parmentier M.... Vassart G. (1992)
- The human olfactory receptor gene family. (PubMed id 14983052)1, 2 Malnic B.... Buck L.B. (2004)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
|
External Searches for OR10D3 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing OR10D3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing OR10D3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing OR10D3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for OR10D3 | Pharmacogenomics, SNPs, Pathways | | HORDE entry for OR10D3 | The Human Olfactory Receptor Data Explorer at the Weizmann Institute of Science |
|
| | |
About This Section
| Patent Information for OR10D3 gene: Search GeneIP for patents involving OR10D3
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for OR10D3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 |
| | | | |  |
 |
| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat OR10D3 | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing OR10D3 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OR10D3 | | Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OR10D3 | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OR10D3 | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OR10D3 |
| |
 |  |  |  | |
| | | Search Tocris compounds for OR10D3 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | OR10D3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | Search ThermoFisher Antibodies for OR10D3 |
| | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat OR10D3 |
|
|
|
|