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Aliases for OR10C1 Gene

Aliases for OR10C1 Gene

  • Olfactory Receptor Family 10 Subfamily C Member 1 (Gene/Pseudogene) 2 3 5
  • Olfactory Receptor, Family 10, Subfamily C, Member 2 2 3
  • Olfactory Receptor, Family 10, Subfamily C, Member 1 2 3
  • Olfactory Receptor 10C2 3 4
  • Hs6M1-17 3 4
  • OR10C2 3 4
  • Olfactory Receptor, Family 10, Subfamily C, Member 1 (Gene/Pseudogene) 2
  • Seven Transmembrane Helix Receptor 3
  • Olfactory Receptor OR6-31 3
  • Olfactory Receptor 10C1 3
  • OR10C1P 3
  • OR6-31 3

External Ids for OR10C1 Gene

Previous HGNC Symbols for OR10C1 Gene

  • OR10C2

Previous GeneCards Identifiers for OR10C1 Gene

  • GC06P029465
  • GC06U900299
  • GC06P029493
  • GC06P029517
  • GC06P029407
  • GC06Po29337

Summaries for OR10C1 Gene

Entrez Gene Summary for OR10C1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jul 2015]

GeneCards Summary for OR10C1 Gene

OR10C1 (Olfactory Receptor Family 10 Subfamily C Member 1 (Gene/Pseudogene)) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR10A4.

UniProtKB/Swiss-Prot for OR10C1 Gene

  • Odorant receptor.

Gene Wiki entry for OR10C1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR10C1 Gene

Genomics for OR10C1 Gene

Regulatory Elements for OR10C1 Gene

Enhancers for OR10C1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around OR10C1 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR10C1 Gene

29,439,306 bp from pter
29,440,977 bp from pter
1,672 bases
Plus strand

Genomic View for OR10C1 Gene

Genes around OR10C1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR10C1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR10C1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

Proteins for OR10C1 Gene

  • Protein details for OR10C1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 10C1
    Protein Accession:
    Secondary Accessions:
    • Q5SUN7
    • Q96R18

    Protein attributes for OR10C1 Gene

    312 amino acids
    Molecular mass:
    34384 Da
    Quaternary structure:
    No Data Available
    • Sequence=CAB44507.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

neXtProt entry for OR10C1 Gene

Post-translational modifications for OR10C1 Gene

  • Glycosylation at Asn 4
  • Modification sites at PhosphoSitePlus

Other Protein References for OR10C1 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR10C1 Gene

Domains & Families for OR10C1 Gene

Gene Families for OR10C1 Gene

Protein Domains for OR10C1 Gene

Suggested Antigen Peptide Sequences for OR10C1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR10C1: view

Function for OR10C1 Gene

Molecular function for OR10C1 Gene

GENATLAS Biochemistry:
olfactory receptor,family 10,subfamily C,member 1,G protein coupled receptor superfamily
UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR10C1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR10C1: view

Phenotypes for OR10C1 Gene

GenomeRNAi human phenotypes for OR10C1:
genes like me logo Genes that share phenotypes with OR10C1: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR10C1 Gene

Localization for OR10C1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR10C1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR10C1 Gene COMPARTMENTS Subcellular localization image for OR10C1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR10C1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR10C1: view

Pathways & Interactions for OR10C1 Gene

genes like me logo Genes that share pathways with OR10C1: view

Pathways by source for OR10C1 Gene

Interacting Proteins for OR10C1 Gene

Gene Ontology (GO) - Biological Process for OR10C1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR10C1: view

No data available for SIGNOR curated interactions for OR10C1 Gene

Drugs & Compounds for OR10C1 Gene

No Compound Related Data Available

Transcripts for OR10C1 Gene

mRNA/cDNA for OR10C1 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR10C1 Gene

No ASD Table

Relevant External Links for OR10C1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR10C1 Gene

mRNA expression in normal human tissues for OR10C1 Gene

NURSA nuclear receptor signaling pathways regulating expression of OR10C1 Gene:


SOURCE GeneReport for Unigene cluster for OR10C1 Gene:

genes like me logo Genes that share expression patterns with OR10C1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for OR10C1 Gene

Orthologs for OR10C1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR10C1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia OR10C1 34
  • 85.58 (n)
  • 85.58 (a)
OR10C1 35
  • 82 (a)
(Canis familiaris)
Mammalia LOC100856344 34
  • 84.24 (n)
  • 84.24 (a)
OR10C1 35
  • 84 (a)
(Mus musculus)
Mammalia Olfr95 34
  • 82.05 (n)
  • 85.9 (a)
Olfr95 16
Olfr95 35
  • 86 (a)
(Pan troglodytes)
Mammalia LOC471942 34
  • 98.82 (n)
  • 97.44 (a)
OR10C1 35
  • 97 (a)
(Rattus norvegicus)
Mammalia Olr1744 34
  • 80.88 (n)
  • 84.62 (a)
(Monodelphis domestica)
Mammalia OR10C1 35
  • 78 (a)
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 52 (a)
(Gallus gallus)
Aves -- 35
  • 42 (a)
(Anolis carolinensis)
Reptilia OR10C1 35
  • 48 (a)
Species where no ortholog for OR10C1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR10C1 Gene

Gene Tree for OR10C1 (if available)
Gene Tree for OR10C1 (if available)

Paralogs for OR10C1 Gene

Paralogs for OR10C1 Gene

(447) SIMAP similar genes for OR10C1 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with OR10C1: view

Variants for OR10C1 Gene

Polymorphic Variants from UniProtKB/Swiss-Prot for OR10C1 Gene

A stop codon at position Gln-55 in the gene coding for this protein is responsible for functional diversity thus producing a pseudogene. The stop codon is more frequent in African-Americans than in non-Africans.

Sequence variations from dbSNP and Humsavar for OR10C1 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
VAR_037822 -
VAR_037823 -
VAR_037824 -
VAR_037825 -
VAR_037826 -

Structural Variations from Database of Genomic Variants (DGV) for OR10C1 Gene

Variant ID Type Subtype PubMed ID
nsv1074389 CNV deletion 25765185
nsv1122126 CNV deletion 24896259
nsv1145096 CNV deletion 24896259
nsv830624 CNV loss 17160897

Variation tolerance for OR10C1 Gene

Residual Variation Intolerance Score: 98.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 11.21; 92.43% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR10C1 Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

Disorders for OR10C1 Gene

Relevant External Links for OR10C1

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for OR10C1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR10C1 Gene

Publications for OR10C1 Gene

  1. Sequence variations at the human leukocyte antigen-linked olfactory receptor cluster do not influence female preferences for male odors. (PMID: 19833159) Thompson E.E. … Ober C. (Hum. Immunol. 2010) 3 46 65
  2. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4 65
  3. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4 65
  4. Personal receptor repertoires: olfaction as a model. (PMID: 22908908) Olender T. … Lancet D. (BMC Genomics 2012) 3 65
  5. A probabilistic classifier for olfactory receptor pseudogenes. (PMID: 16939646) Menashe I. … Lancet D. (BMC Bioinformatics 2006) 3 65

Products for OR10C1 Gene

Sources for OR10C1 Gene

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