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Aliases for OR10AG1 Gene

Aliases for OR10AG1 Gene

  • Olfactory Receptor, Family 10, Subfamily AG, Member 1 2 3
  • Olfactory Receptor OR11-160 3 4
  • Olfactory Receptor 10AG1 3
  • OR11-160 3

External Ids for OR10AG1 Gene

Previous GeneCards Identifiers for OR10AG1 Gene

  • GC00U903069
  • GC11U900153
  • GC11M055493
  • GC11M055737

Summaries for OR10AG1 Gene

Entrez Gene Summary for OR10AG1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR10AG1 Gene

OR10AG1 (Olfactory Receptor, Family 10, Subfamily AG, Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR10A3.

UniProtKB/Swiss-Prot for OR10AG1 Gene

  • Odorant receptor.

Gene Wiki entry for OR10AG1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR10AG1 Gene

Genomics for OR10AG1 Gene

Regulatory Elements for OR10AG1 Gene

Genomic Location for OR10AG1 Gene

Start:
55,967,558 bp from pter
End:
55,968,463 bp from pter
Size:
906 bases
Orientation:
Minus strand

Genomic View for OR10AG1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR10AG1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR10AG1 Gene

Proteins for OR10AG1 Gene

  • Protein details for OR10AG1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NH19-O10AG_HUMAN
    Recommended name:
    Olfactory receptor 10AG1
    Protein Accession:
    Q8NH19
    Secondary Accessions:
    • B2RNH4
    • Q6IEU3

    Protein attributes for OR10AG1 Gene

    Size:
    301 amino acids
    Molecular mass:
    34105 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR10AG1 Gene

Proteomics data for OR10AG1 Gene at MOPED

Post-translational modifications for OR10AG1 Gene

  • Glycosylation at Asn82
  • Modification sites at PhosphoSitePlus

Other Protein References for OR10AG1 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR10AG1 Gene

Domains for OR10AG1 Gene

Gene Families for OR10AG1 Gene

HGNC:
  • OR10 :GPCR / Class A : Olfactory receptors

Protein Domains for OR10AG1 Gene

Suggested Antigen Peptide Sequences for OR10AG1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NH19

UniProtKB/Swiss-Prot:

O10AG_HUMAN :
  • Q8NH19
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR10AG1: view

Function for OR10AG1 Gene

Molecular function for OR10AG1 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR10AG1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR10AG1: view
genes like me logo Genes that share phenotypes with OR10AG1: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR10AG1

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR10AG1 Gene

Localization for OR10AG1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR10AG1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR10AG1 Gene COMPARTMENTS Subcellular localization image for OR10AG1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR10AG1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR10AG1: view

Pathways for OR10AG1 Gene

genes like me logo Genes that share pathways with OR10AG1: view

Pathways by source for OR10AG1 Gene

1 KEGG pathway for OR10AG1 Gene

Interacting Proteins for OR10AG1 Gene

Gene Ontology (GO) - Biological Process for OR10AG1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR10AG1: view

Transcripts for OR10AG1 Gene

mRNA/cDNA for OR10AG1 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR10AG1

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for OR10AG1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR10AG1 Gene

No ASD Table

Relevant External Links for OR10AG1 Gene

GeneLoc Exon Structure for
OR10AG1
ECgene alternative splicing isoforms for
OR10AG1

Expression for OR10AG1 Gene

mRNA expression in normal human tissues for OR10AG1 Gene

SOURCE GeneReport for Unigene cluster for OR10AG1 Gene Hs.554525

genes like me logo Genes that share expressions with OR10AG1: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for OR10AG1 Gene

Orthologs for OR10AG1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR10AG1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia -- 36
  • 71 (a)
OneToMany
-- 36
  • 63 (a)
OneToMany
LOC787428 35
  • 73.99 (n)
  • 66.55 (a)
dog
(Canis familiaris)
Mammalia LOC100686203 35
  • 84.44 (n)
  • 80.33 (a)
OR10AG1 36
  • 80 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Olfr1118 36
  • 72 (a)
OneToMany
Olfr1122 36
  • 66 (a)
OneToMany
Olfr1123 35
  • 79.01 (n)
  • 74.74 (a)
Olfr1123 16
Olfr1123 36
  • 69 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 52 (a)
OneToMany
-- 36
  • 52 (a)
OneToMany
-- 36
  • 54 (a)
OneToMany
-- 36
  • 53 (a)
OneToMany
-- 36
  • 52 (a)
OneToMany
-- 36
  • 51 (a)
OneToMany
-- 36
  • 56 (a)
OneToMany
-- 36
  • 58 (a)
OneToMany
-- 36
  • 59 (a)
OneToMany
-- 36
  • 59 (a)
OneToMany
-- 36
  • 57 (a)
OneToMany
-- 36
  • 58 (a)
OneToMany
-- 36
  • 56 (a)
OneToMany
-- 36
  • 58 (a)
OneToMany
-- 36
  • 59 (a)
OneToMany
-- 36
  • 58 (a)
OneToMany
-- 36
  • 59 (a)
OneToMany
-- 36
  • 58 (a)
OneToMany
-- 36
  • 59 (a)
OneToMany
-- 36
  • 59 (a)
OneToMany
-- 36
  • 57 (a)
OneToMany
-- 36
  • 58 (a)
OneToMany
-- 36
  • 58 (a)
OneToMany
-- 36
  • 58 (a)
OneToMany
-- 36
  • 56 (a)
OneToMany
-- 36
  • 58 (a)
OneToMany
-- 36
  • 54 (a)
OneToMany
-- 36
  • 56 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Olr561 35
  • 77.97 (n)
  • 73.7 (a)
Species with no ortholog for OR10AG1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR10AG1 Gene

ENSEMBL:
Gene Tree for OR10AG1 (if available)
TreeFam:
Gene Tree for OR10AG1 (if available)

Paralogs for OR10AG1 Gene

Paralogs for OR10AG1 Gene

Selected SIMAP similar genes for OR10AG1 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for OR10AG1 Gene

genes like me logo Genes that share paralogs with OR10AG1: view

Variants for OR10AG1 Gene

Sequence variations from dbSNP and Humsavar for OR10AG1 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs7110317 -- 55,968,590(+) GATAC(A/G)GGAAT upstream-variant-2KB
rs7110851 -- 55,968,977(+) CAATT(A/C)TCTTA upstream-variant-2KB
rs7114535 -- 55,968,905(+) GCCCT(G/T)GAATA upstream-variant-2KB
rs7127105 -- 55,969,714(+) TTATT(A/G)GACAT upstream-variant-2KB
rs7940327 -- 55,970,336(+) ACACG(A/T)ACATG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR10AG1 Gene

Variant ID Type Subtype PubMed ID
esv2751030 CNV Gain 17911159
nsv821668 CNV Loss 15273396
nsv437718 CNV Loss 16327808
nsv468568 CNV Loss 19166990
nsv469959 CNV Loss 18288195
nsv517590 CNV Loss 19592680
dgv52e55 CNV Loss 17911159
dgv384e1 CNV Complex 17122850

Relevant External Links for OR10AG1 Gene

HapMap Linkage Disequilibrium report
OR10AG1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR10AG1 Gene

Disorders for OR10AG1 Gene

No disorders were found for OR10AG1 Gene.

No data available for UniProtKB/Swiss-Prot for OR10AG1 Gene

Publications for OR10AG1 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for OR10AG1 Gene

Sources for OR10AG1 Gene

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