Free for academic non-profit institutions. Other users need a Commercial license

Aliases for OR10A6 Gene

Aliases for OR10A6 Gene

  • Olfactory Receptor Family 10 Subfamily A Member 6 (Gene/Pseudogene) 2 3 5
  • Olfactory Receptor OR11-96 3 4
  • Olfactory Receptor, Family 10, Subfamily A, Member 6 (Gene/Pseudogene) 2
  • Olfactory Receptor, Family 10, Subfamily A, Member 6 3
  • OR11-96 3

External Ids for OR10A6 Gene

Previous GeneCards Identifiers for OR10A6 Gene

  • GC11U990581
  • GC11M007914
  • GC11M007905
  • GC11M007949

Summaries for OR10A6 Gene

Entrez Gene Summary for OR10A6 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jun 2015]

GeneCards Summary for OR10A6 Gene

OR10A6 (Olfactory Receptor Family 10 Subfamily A Member 6 (Gene/Pseudogene)) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR10A3.

UniProtKB/Swiss-Prot for OR10A6 Gene

  • Odorant receptor.

Gene Wiki entry for OR10A6 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR10A6 Gene

Genomics for OR10A6 Gene

Regulatory Elements for OR10A6 Gene

Enhancers for OR10A6 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around OR10A6 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR10A6 Gene

7,927,718 bp from pter
7,928,662 bp from pter
945 bases
Minus strand

Genomic View for OR10A6 Gene

Genes around OR10A6 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR10A6 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR10A6 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR10A6 Gene

Proteins for OR10A6 Gene

  • Protein details for OR10A6 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 10A6
    Protein Accession:
    Secondary Accessions:
    • Q6IF59

    Protein attributes for OR10A6 Gene

    314 amino acids
    Molecular mass:
    35318 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR10A6 Gene

Proteomics data for OR10A6 Gene at MOPED

Post-translational modifications for OR10A6 Gene

Other Protein References for OR10A6 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR10A6 Gene

Domains & Families for OR10A6 Gene

Gene Families for OR10A6 Gene

Protein Domains for OR10A6 Gene

Suggested Antigen Peptide Sequences for OR10A6 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR10A6: view

Function for OR10A6 Gene

Molecular function for OR10A6 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Phenotypes for OR10A6 Gene

GenomeRNAi human phenotypes for OR10A6:
genes like me logo Genes that share phenotypes with OR10A6: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR10A6 Gene

Localization for OR10A6 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR10A6 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR10A6 Gene COMPARTMENTS Subcellular localization image for OR10A6 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR10A6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA,IBA --
genes like me logo Genes that share ontologies with OR10A6: view

Pathways & Interactions for OR10A6 Gene

genes like me logo Genes that share pathways with OR10A6: view

Pathways by source for OR10A6 Gene

Interacting Proteins for OR10A6 Gene

Gene Ontology (GO) - Biological Process for OR10A6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA,IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR10A6: view

No data available for SIGNOR curated interactions for OR10A6 Gene

Drugs & Compounds for OR10A6 Gene

No Compound Related Data Available

Transcripts for OR10A6 Gene

mRNA/cDNA for OR10A6 Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(2) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR10A6 Gene

Olfactory receptor, family 10, subfamily A, member 6:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for OR10A6 Gene

No ASD Table

Relevant External Links for OR10A6 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR10A6 Gene

mRNA expression in normal human tissues for OR10A6 Gene

mRNA differential expression in normal tissues according to GTEx for OR10A6 Gene

This gene is overexpressed in Skin - Sun Exposed (Lower leg) (x19.0) and Skin - Not Sun Exposed (Suprapubic) (x13.6).

SOURCE GeneReport for Unigene cluster for OR10A6 Gene Hs.528593

genes like me logo Genes that share expression patterns with OR10A6: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for OR10A6 Gene

Orthologs for OR10A6 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR10A6 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia OR10A3 35
  • 84.98 (n)
  • 84.03 (a)
OR10A6 36
  • 87 (a)
(Canis familiaris)
Mammalia OR10A6 35
  • 87.54 (n)
  • 86.9 (a)
OR10A6 36
  • 87 (a)
(Mus musculus)
Mammalia Olfr519 35
  • 78.7 (n)
  • 75.08 (a)
Olfr519 16
Olfr512 36
  • 74 (a)
Olfr514 36
  • 75 (a)
Olfr516 36
  • 78 (a)
Olfr517 36
  • 79 (a)
Olfr518 36
  • 73 (a)
Olfr519 36
  • 74 (a)
(Pan troglodytes)
Mammalia LOC466433 35
  • 99.04 (n)
  • 98.73 (a)
OR10A6 36
  • 99 (a)
(Rattus norvegicus)
Mammalia LOC100912408 35
  • 80.19 (n)
  • 78.27 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 54 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 45 (a)
Species with no ortholog for OR10A6:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR10A6 Gene

Gene Tree for OR10A6 (if available)
Gene Tree for OR10A6 (if available)

Paralogs for OR10A6 Gene

Paralogs for OR10A6 Gene

(450) SIMAP similar genes for OR10A6 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR10A6: view

Variants for OR10A6 Gene

Sequence variations from dbSNP and Humsavar for OR10A6 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs7928451 - 7,928,313(+) CCATT(A/G)CTCCC reference, missense
rs7933807 - 7,928,244(+) TAAAA(A/C)CTCCT reference, missense
rs4758258 - 7,927,803(+) TAAGC(A/G)GATTC reference, missense
rs1158007 -- 7,927,410(+) AGAAT(A/T)TATGA downstream-variant-500B
rs1397594 -- 7,928,731(+) CATTA(A/G)CTAAG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR10A6 Gene

Variant ID Type Subtype PubMed ID
nsv7215 OTHER Inversion 18451855
nsv499766 OTHER Inversion 21111241
nsv522758 CNV Loss 19592680
nsv527100 CNV Loss 19592680

Variation tolerance for OR10A6 Gene

Residual Variation Intolerance Score: 82.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 14.87; 96.74% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for OR10A6 Gene

Disorders for OR10A6 Gene

Relevant External Links for OR10A6

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for OR10A6 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR10A6 Gene

Publications for OR10A6 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 67
  2. Personal receptor repertoires: olfaction as a model. (PMID: 22908908) Olender T. … Lancet D. (BMC Genomics 2012) 3
  3. A probabilistic classifier for olfactory receptor pseudogenes. (PMID: 16939646) Menashe I. … Lancet D. (BMC Bioinformatics 2006) 3

Products for OR10A6 Gene

Sources for OR10A6 Gene