Free for academic non-profit institutions. Other users need a Commercial license

Aliases for OR10A5 Gene

Aliases for OR10A5 Gene

  • Olfactory Receptor, Family 10, Subfamily A, Member 5 2 3
  • OR10A1 3 4 6
  • Olfactory Receptor-Like Protein JCG6 3 4
  • Olfactory Receptor 11-403 3 4
  • Olfactory Receptor 10A1 3 4
  • OR11-403 3 4
  • HP3 3 4
  • Olfactory Receptor, Family 10, Subfamily A, Member 1 3
  • Olfactory Receptor OR11-85 3
  • Olfactory Receptor 10A5 3
  • JCG6 3

External Ids for OR10A5 Gene

Previous HGNC Symbols for OR10A5 Gene

  • OR10A1

Previous GeneCards Identifiers for OR10A5 Gene

  • GC11U990582
  • GC11P006833
  • GC11P006823

Summaries for OR10A5 Gene

Entrez Gene Summary for OR10A5 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR10A5 Gene

OR10A5 (Olfactory Receptor, Family 10, Subfamily A, Member 5) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR10A3.

UniProtKB/Swiss-Prot for OR10A5 Gene

  • Odorant receptor (Potential). May be involved in taste perception.

Gene Wiki entry for OR10A5 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR10A5 Gene

Genomics for OR10A5 Gene

Regulatory Elements for OR10A5 Gene

Genomic Location for OR10A5 Gene

6,845,652 bp from pter
6,846,705 bp from pter
1,054 bases
Plus strand

Genomic View for OR10A5 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR10A5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR10A5 Gene

Proteins for OR10A5 Gene

  • Protein details for OR10A5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 10A5
    Protein Accession:
    Secondary Accessions:
    • O95223
    • Q52M66
    • Q96R21
    • Q96R22

    Protein attributes for OR10A5 Gene

    317 amino acids
    Molecular mass:
    35519 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR10A5 Gene

Proteomics data for OR10A5 Gene at MOPED

Post-translational modifications for OR10A5 Gene

  • Glycosylation at Asn5
  • Modification sites at PhosphoSitePlus

Other Protein References for OR10A5 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR10A5 Gene

Domains for OR10A5 Gene

Gene Families for OR10A5 Gene

  • OR10 :GPCR / Class A : Olfactory receptors

Protein Domains for OR10A5 Gene

Suggested Antigen Peptide Sequences for OR10A5 Gene

Graphical View of Domain Structure for InterPro Entry



  • Q9H207
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR10A5: view

Function for OR10A5 Gene

Molecular function for OR10A5 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor (Potential). May be involved in taste perception.

Gene Ontology (GO) - Molecular Function for OR10A5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity NAS 9787077
genes like me logo Genes that share ontologies with OR10A5: view

Phenotypes for OR10A5 Gene

MGI mutant phenotypes for OR10A5:
inferred from 2 alleles
GenomeRNAi human phenotypes for OR10A5:
genes like me logo Genes that share phenotypes with OR10A5: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR10A5

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR10A5 Gene

Localization for OR10A5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR10A5 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR10A5 Gene COMPARTMENTS Subcellular localization image for OR10A5 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR10A5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane NAS 9787077
genes like me logo Genes that share ontologies with OR10A5: view

Pathways for OR10A5 Gene

genes like me logo Genes that share pathways with OR10A5: view

Pathways by source for OR10A5 Gene

1 KEGG pathway for OR10A5 Gene

Interacting Proteins for OR10A5 Gene

Gene Ontology (GO) - Biological Process for OR10A5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell NAS 9787077
GO:0050911 detection of chemical stimulus involved in sensory perception of smell NAS 9787077
genes like me logo Genes that share ontologies with OR10A5: view

Transcripts for OR10A5 Gene

mRNA/cDNA for OR10A5 Gene

(2) Selected AceView cDNA sequences:
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR10A5

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for OR10A5

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR10A5 Gene

No ASD Table

Relevant External Links for OR10A5 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR10A5 Gene

mRNA expression in normal human tissues for OR10A5 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for OR10A5 Gene

SOURCE GeneReport for Unigene cluster for OR10A5 Gene Hs.447478

mRNA Expression by UniProt/SwissProt for OR10A5 Gene

Tissue specificity: Expressed in the tongue
genes like me logo Genes that share expressions with OR10A5: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for OR10A5 Gene

Orthologs for OR10A5 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR10A5 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC466419 35
  • 99.16 (n)
  • 98.74 (a)
OR10A5 36
  • 98 (a)
(Bos Taurus)
Mammalia -- 36
  • 91 (a)
-- 36
  • 90 (a)
-- 36
  • 88 (a)
-- 36
  • 88 (a)
LOC790683 35
  • 88.96 (n)
  • 91.17 (a)
(Canis familiaris)
Mammalia -- 36
  • 92 (a)
-- 36
  • 92 (a)
-- 36
  • 93 (a)
cOR10A9 35
  • 89.17 (n)
  • 93.06 (a)
OR10B10 36
  • 91 (a)
(Mus musculus)
Mammalia Olfr713 35
  • 89.35 (n)
  • 92.41 (a)
Olfr713 16
Olfr713 36
  • 90 (a)
Olfr714 36
  • 89 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 76 (a)
-- 36
  • 75 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 72 (a)
(Rattus norvegicus)
Mammalia Olr227 35
  • 88.29 (n)
  • 90.51 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 48 (a)
Species with no ortholog for OR10A5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR10A5 Gene

Gene Tree for OR10A5 (if available)
Gene Tree for OR10A5 (if available)

Paralogs for OR10A5 Gene

Paralogs for OR10A5 Gene

Selected SIMAP similar genes for OR10A5 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with OR10A5: view

Variants for OR10A5 Gene

Sequence variations from dbSNP and Humsavar for OR10A5 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs1449131 -- 6,845,353(+) CATCC(A/T)TTCCC upstream-variant-2KB
rs1449132 -- 6,845,398(+) AAATA(C/T)GATAC upstream-variant-2KB
rs1449133 -- 6,845,435(+) GCTAA(A/C)AAGAT upstream-variant-2KB
rs1449134 -- 6,845,491(+) TTTCA(C/G)TGCTT upstream-variant-2KB
rs2595437 -- 6,844,527(+) TGCTC(C/T)GGAAG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR10A5 Gene

Variant ID Type Subtype PubMed ID
nsv832060 CNV Gain 17160897
nsv467701 CNV Loss 19166990

Relevant External Links for OR10A5 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR10A5 Gene

Disorders for OR10A5 Gene

Relevant External Links for OR10A5

Genetic Association Database (GAD)
genes like me logo Genes that share disorders with OR10A5: view

No data available for UniProtKB/Swiss-Prot for OR10A5 Gene

Publications for OR10A5 Gene

  1. Organization and evolution of olfactory receptor genes on human chromosome 11. (PMID: 9787077) Buettner J.A. … Evans G.A. (Genomics 1998) 3 4
  2. Genomic analysis of orthologous mouse and human olfactory receptor loci. (PMID: 11416212) Lane R.P. … Trask B.J. (Proc. Natl. Acad. Sci. U.S.A. 2001) 3 4
  3. New GPCRs from a human lingual cDNA library. (PMID: 11705801) Gaudin J.-C. … Haertle T. (Chem. Senses 2001) 3 4
  4. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4

Products for OR10A5 Gene

Sources for OR10A5 Gene

Back to Top