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Aliases for OR10A5 Gene

Aliases for OR10A5 Gene

  • Olfactory Receptor, Family 10, Subfamily A, Member 5 2 3
  • OR10A1 3 4 6
  • Olfactory Receptor-Like Protein JCG6 3 4
  • Olfactory Receptor 11-403 3 4
  • Olfactory Receptor 10A1 3 4
  • OR11-403 3 4
  • HP3 3 4
  • Olfactory Receptor, Family 10, Subfamily A, Member 1 3
  • Olfactory Receptor OR11-85 3
  • Olfactory Receptor 10A5 3
  • JCG6 3

External Ids for OR10A5 Gene

Previous Symbols for OR10A5 Gene

  • OR10A1

Summaries for OR10A5 Gene

Entrez Gene Summary for OR10A5 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR10A5 Gene

OR10A5 (Olfactory Receptor, Family 10, Subfamily A, Member 5) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR10A3.

UniProtKB/Swiss-Prot for OR10A5 Gene

  • Odorant receptor (Potential). May be involved in taste perception.

Gene Wiki entry for OR10A5 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR10A5 Gene

Genomics for OR10A5 Gene

Genomic Location for OR10A5 Gene

Start:
6,845,652 bp from pter
End:
6,846,705 bp from pter
Size:
1,054 bases
Orientation:
Plus strand

Genomic View for OR10A5 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR10A5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR10A5 Gene

Regulatory Elements for OR10A5 Gene

Proteins for OR10A5 Gene

  • Protein details for OR10A5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H207-O10A5_HUMAN
    Recommended name:
    Olfactory receptor 10A5
    Protein Accession:
    Q9H207
    Secondary Accessions:
    • O95223
    • Q52M66
    • Q96R21
    • Q96R22

    Protein attributes for OR10A5 Gene

    Size:
    317 amino acids
    Molecular mass:
    35519 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR10A5 Gene

Proteomics data for OR10A5 Gene at MOPED

Post-translational modifications for OR10A5 Gene

Other Protein References for OR10A5 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR10A5 Gene

Domains for OR10A5 Gene

Gene Families for OR10A5 Gene

HGNC:
  • OR10 :GPCR / Class A : Olfactory receptors

Protein Domains for OR10A5 Gene

UniProtKB/Swiss-Prot:

O10A5_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q9H207
genes like me logo Genes that share domains with OR10A5: view

Function for OR10A5 Gene

Molecular function for OR10A5 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor (Potential). May be involved in taste perception.

Gene Ontology (GO) - Molecular Function for OR10A5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity NAS 9787077
genes like me logo Genes that share ontologies with OR10A5: view

Phenotypes for OR10A5 Gene

MGI mutant phenotypes for OR10A5:
inferred from 2 alleles
GenomeRNAi human phenotypes for OR10A5:
genes like me logo Genes that share phenotypes with OR10A5: view

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR10A5 Gene

Localization for OR10A5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR10A5 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR10A5 Gene COMPARTMENTS Subcellular localization image for OR10A5 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR10A5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane NAS 9787077
genes like me logo Genes that share ontologies with OR10A5: view

Pathways for OR10A5 Gene

genes like me logo Genes that share pathways with OR10A5: view

Pathways by source for OR10A5 Gene

1 KEGG pathway for OR10A5 Gene

Interacting Proteins for OR10A5 Gene

Gene Ontology (GO) - Biological Process for OR10A5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell NAS 9787077
GO:0050911 detection of chemical stimulus involved in sensory perception of smell NAS 9787077
genes like me logo Genes that share ontologies with OR10A5: view

Transcripts for OR10A5 Gene

mRNA/cDNA for OR10A5 Gene

(1) REFSEQ mRNAs :
(2) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR10A5 Gene

No ASD Table

Relevant External Links for OR10A5 Gene

GeneLoc Exon Structure for
OR10A5
ECgene alternative splicing isoforms for
OR10A5

Expression for OR10A5 Gene

mRNA expression in normal human tissues for OR10A5 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for OR10A5 Gene

SOURCE GeneReport for Unigene cluster for OR10A5 Gene Hs.447478

mRNA Expression by UniProt/SwissProt for OR10A5 Gene

Q9H207-O10A5_HUMAN
Tissue specificity: Expressed in the tongue
genes like me logo Genes that share expressions with OR10A5: view

Orthologs for OR10A5 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR10A5 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC466419 36
  • 99.16 (n)
  • 98.74 (a)
OR10A5 37
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 37
  • 91 (a)
ManyToMany
-- 37
  • 90 (a)
ManyToMany
-- 37
  • 88 (a)
ManyToMany
-- 37
  • 88 (a)
ManyToMany
LOC790683 36
  • 88.96 (n)
  • 91.17 (a)
dog
(Canis familiaris)
Mammalia -- 37
  • 92 (a)
ManyToMany
-- 37
  • 92 (a)
ManyToMany
-- 37
  • 93 (a)
ManyToMany
cOR10A9 36
  • 89.17 (n)
  • 93.06 (a)
OR10B10 37
  • 91 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Olfr713 36
  • 89.35 (n)
  • 92.41 (a)
Olfr713 16
Olfr713 37
  • 90 (a)
ManyToMany
Olfr714 37
  • 89 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 76 (a)
ManyToMany
-- 37
  • 75 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 72 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Olr227 36
  • 88.29 (n)
  • 90.51 (a)
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 48 (a)
OneToMany
Species with no ortholog for OR10A5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR10A5 Gene

ENSEMBL:
Gene Tree for OR10A5 (if available)
TreeFam:
Gene Tree for OR10A5 (if available)

Paralogs for OR10A5 Gene

Paralogs for OR10A5 Gene

Selected SIMAP similar genes for OR10A5 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with OR10A5: view

Variants for OR10A5 Gene

Sequence variations from dbSNP and Humsavar for OR10A5 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs1449131 -- 6,845,353(+) CATCC(A/T)TTCCC upstream-variant-2KB
rs1449132 -- 6,845,398(+) AAATA(C/T)GATAC upstream-variant-2KB
rs1449133 -- 6,845,435(+) GCTAA(A/C)AAGAT upstream-variant-2KB
rs1449134 -- 6,845,491(+) TTTCA(C/G)TGCTT upstream-variant-2KB
rs2595437 -- 6,844,527(+) TGCTC(C/T)GGAAG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR10A5 Gene

Variant ID Type Subtype PubMed ID
nsv832060 CNV Gain 17160897
nsv467701 CNV Loss 19166990

Relevant External Links for OR10A5 Gene

HapMap Linkage Disequilibrium report
OR10A5

Disorders for OR10A5 Gene

Relevant External Links for OR10A5

Genetic Association Database (GAD)
OR10A5
genes like me logo Genes that share disorders with OR10A5: view

No data available for UniProtKB/Swiss-Prot for OR10A5 Gene

Publications for OR10A5 Gene

  1. Organization and evolution of olfactory receptor genes on human chromosome 11. (PMID: 9787077) Buettner J.A. … Evans G.A. (Genomics 1998) 3 4
  2. Genomic analysis of orthologous mouse and human olfactory receptor loci. (PMID: 11416212) Lane R.P. … Trask B.J. (Proc. Natl. Acad. Sci. U.S.A. 2001) 3 4
  3. New GPCRs from a human lingual cDNA library. (PMID: 11705801) Gaudin J.-C. … Haertle T. (Chem. Senses 2001) 3 4
  4. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4

Products for OR10A5 Gene

Sources for OR10A5 Gene

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