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Aliases for OR10A2 Gene

Aliases for OR10A2 Gene

  • Olfactory Receptor, Family 10, Subfamily A, Member 2 2 3
  • Olfactory Receptor OR11-86 3 4
  • OR10A2P 3 4
  • Olfactory Receptor, Family 10, Subfamily A, Member 2 Pseudogene 3
  • Olfactory Receptor OR11-82 Pseudogene 3
  • Olfactory Receptor 10A2 3
  • HP4 Olfactory Receptor 3
  • OR11-82 3
  • OR11-86 3
  • OST363 3
  • HP4 4

External Ids for OR10A2 Gene

Previous HGNC Symbols for OR10A2 Gene

  • OR10A2P

Previous GeneCards Identifiers for OR10A2 Gene

  • GC11P006850
  • GC11P006841

Summaries for OR10A2 Gene

Entrez Gene Summary for OR10A2 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR10A2 Gene

OR10A2 (Olfactory Receptor, Family 10, Subfamily A, Member 2) is a Protein Coding gene. Diseases associated with OR10A2 include vasomotor rhinitis. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR10A3.

UniProtKB/Swiss-Prot for OR10A2 Gene

  • Odorant receptor.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR10A2 Gene

Genomics for OR10A2 Gene

Regulatory Elements for OR10A2 Gene

Genomic Location for OR10A2 Gene

6,869,693 bp from pter
6,870,745 bp from pter
1,053 bases
Plus strand

Genomic View for OR10A2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR10A2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR10A2 Gene

Proteins for OR10A2 Gene

  • Protein details for OR10A2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 10A2
    Protein Accession:
    Secondary Accessions:
    • B2RNL9
    • Q6IFG9

    Protein attributes for OR10A2 Gene

    303 amino acids
    Molecular mass:
    33817 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAG45207.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for OR10A2 Gene

Proteomics data for OR10A2 Gene at MOPED

Post-translational modifications for OR10A2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for OR10A2 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR10A2 Gene

Domains for OR10A2 Gene

Gene Families for OR10A2 Gene

Protein Domains for OR10A2 Gene

Suggested Antigen Peptide Sequences for OR10A2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR10A2: view

Function for OR10A2 Gene

Molecular function for OR10A2 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR10A2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR10A2: view

Phenotypes for OR10A2 Gene

MGI mutant phenotypes for OR10A2:
inferred from 1 alleles
genes like me logo Genes that share phenotypes with OR10A2: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR10A2

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR10A2 Gene

Localization for OR10A2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR10A2 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR10A2 Gene COMPARTMENTS Subcellular localization image for OR10A2 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR10A2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR10A2: view

Pathways for OR10A2 Gene

genes like me logo Genes that share pathways with OR10A2: view

Pathways by source for OR10A2 Gene

1 BioSystems pathway for OR10A2 Gene
1 KEGG pathway for OR10A2 Gene

Interacting Proteins for OR10A2 Gene

Gene Ontology (GO) - Biological Process for OR10A2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR10A2: view

Transcripts for OR10A2 Gene

mRNA/cDNA for OR10A2 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR10A2

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR10A2 Gene

No ASD Table

Relevant External Links for OR10A2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR10A2 Gene

mRNA expression in normal human tissues for OR10A2 Gene

SOURCE GeneReport for Unigene cluster for OR10A2 Gene Hs.371762

genes like me logo Genes that share expressions with OR10A2: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for OR10A2 Gene

Orthologs for OR10A2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR10A2 Gene

Organism Taxonomy Gene Similarity Type Details
(Mus musculus)
Mammalia Olfr714 35
  • 88.08 (n)
  • 89.74 (a)
Olfr714 16
Olfr713 36
  • 86 (a)
Olfr714 36
  • 85 (a)
(Rattus norvegicus)
Mammalia Olr230 35
  • 87.31 (n)
  • 88.41 (a)
(Bos Taurus)
Mammalia -- 36
  • 88 (a)
-- 36
  • 87 (a)
-- 36
  • 84 (a)
-- 36
  • 84 (a)
(Canis familiaris)
Mammalia -- 36
  • 89 (a)
-- 36
  • 89 (a)
-- 36
  • 90 (a)
OR10B10 36
  • 89 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 73 (a)
-- 36
  • 72 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 71 (a)
(Gallus gallus)
Aves -- 36
  • 47 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 46 (a)
Species with no ortholog for OR10A2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR10A2 Gene

Gene Tree for OR10A2 (if available)
Gene Tree for OR10A2 (if available)

Paralogs for OR10A2 Gene

Paralogs for OR10A2 Gene

(457) SIMAP similar genes for OR10A2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR10A2: view

Variants for OR10A2 Gene

Sequence variations from dbSNP and Humsavar for OR10A2 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs2595454 -- 6,868,691(-) AAACT(A/C/G)TGGTT upstream-variant-2KB
rs2741763 -- 6,871,089(-) GGGCA(C/T)CTGTA downstream-variant-500B
rs2741764 - 6,870,154(-) GGAGG(C/T)AGCAG missense, reference
rs3930075 - 6,869,882(+) GCTAC(A/G)CAGCC reference, missense
rs4300376 -- 6,868,905(+) ATGCT(A/G)ATGAT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR10A2 Gene

Variant ID Type Subtype PubMed ID
nsv467701 CNV Loss 19166990
nsv832061 CNV Loss 17160897
esv2664185 CNV Deletion 23128226

Relevant External Links for OR10A2 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR10A2 Gene

Disorders for OR10A2 Gene

MalaCards: The human disease database

MalaCards: The human disease database.

Search for OR10A2 Gene in MalaCards »

(1) Disease for OR10A2 Gene

Relevant External Links for OR10A2

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with OR10A2: view

No data available for OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for OR10A2 Gene

Publications for OR10A2 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  2. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 3 4
  3. Olfactory receptor gene polymorphisms and nonallergic vasomotor rhinitis. (PMID: 18446592) Bernstein J.A. … Nebert D.W. (J Asthma 2008) 3 48
  4. Genomic analysis of orthologous mouse and human olfactory receptor loci. (PMID: 11416212) Lane R.P. … Trask B.J. (Proc. Natl. Acad. Sci. U.S.A. 2001) 3 4
  5. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4

Products for OR10A2 Gene

Sources for OR10A2 Gene

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