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OPN5 Gene

protein-coding   GIFtS: 53
GCID: GC06P047749

Opsin 5

(Previous name: transmembrane protein 13)
(Previous symbol: TMEM13)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Opsin 51 2     G-Protein Coupled Receptor 1362 3
Transmembrane Protein 131 2 3     GRP1362 5
TMEM131 2 3     opsin-52
PGR122 3 5     Neuropsin3
neuropsin1 2     G-Protein Coupled Receptor PGR123
GPR1362 3     

External Ids:    HGNC: 199921   Entrez Gene: 2213912   Ensembl: ENSG000001248187   OMIM: 6090425   UniProtKB: Q6U7363   

Export aliases for OPN5 gene to outside databases

Previous GC identifers: GC06P047796 GC06P047857 GC06P047477


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for OPN5 Gene:
Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This opsin
gene is expressed in the eye, brain, testes, and spinal cord. This gene belongs to the seven-exon subfamily of
mammalian opsin genes that includes peropsin (RRH) and retinal G protein coupled receptor (RGR). Like these other
seven-exon opsin genes, this family member may encode a protein with photoisomerase activity. Alternative
splicing results in multiple transcript variants. (provided by RefSeq, Jun 2010)

GeneCards Summary for OPN5 Gene:
OPN5 (opsin 5) is a protein-coding gene. GO annotations related to this gene include photoreceptor activity and G-protein coupled receptor activity. An important paralog of this gene is OPN3.

Gene Wiki entry for OPN5 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000006.11  NT_007592.16  NC_018917.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the OPN5 gene promoter:
         AhR   STAT5B   ISGF-3   POU2F1   STAT5A   Arnt   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): OPN5 promoter sequence
   Search Chromatin IP Primers for OPN5

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat OPN5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p12.3   Ensembl cytogenetic band:  6p12.3   HGNC cytogenetic band: 6p12.3

OPN5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
OPN5 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P047749:  view genomic region     (about GC identifiers)

Start:
47,749,718 bp from pter      End:
47,800,516 bp from pter
Size:
50,799 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: OPN5_HUMAN, Q6U736 (See protein sequence)
Recommended Name: Opsin-5  
Size: 354 amino acids; 39727 Da
Sequence caution: Sequence=CAI20454.1; Type=Erroneous gene model prediction;
Secondary accessions: A0AV33 Q5T5B9 Q5T886 Q7Z603 Q86SL5

Explore the universe of human proteins at neXtProt for OPN5: NX_Q6U736

Explore proteomics data for OPN5 at MOPED

Post-translational modifications: 

  • It is uncertain whether Cys-315 or Cys-316 is palmitoylated1
  • Glycosylation2 at Asn4
  • Modification sites at PhosphoSitePlus

  • See OPN5 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_859528.1  
    ENSEMBL proteins: 
     ENSP00000426991   ENSP00000360255   ENSP00000377302  
    Reactome Protein details: Q6U736

    OPN5 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for OPN5

     
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    Search eBioscience for ELISAs for OPN5 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    OPN: GPCR / Class A : Opsin receptors

    IUPHAR Guide to PHARMACOLOGY protein family classification: OPN5
    Class A Orphans

    4 InterPro protein domains:
     IPR017452 GPCR_Rhodpsn_7TM
     IPR002962 Peropsin
     IPR027430 Retinal_BS
     IPR000276 GPCR_Rhodpsn

    Graphical View of Domain Structure for InterPro Entry Q6U736

    ProtoNet protein and cluster: Q6U736

    1 Blocks protein domain: IPB001760 Opsin

    UniProtKB/Swiss-Prot: OPN5_HUMAN, Q6U736
    Similarity: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily


    Find genes that share domains with OPN5           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004930G-protein coupled receptor activity IEA--
    GO:0009881photoreceptor activity IEA--
         
    Find genes that share ontologies with OPN5           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for OPN5:
     Increased circadian period len  Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for OPN5
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    miRNA
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    Block miRNA regulation of human, mouse, rat OPN5 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate OPN5 (see all 18):
    hsa-miR-448 hsa-miR-513a-5p hsa-miR-3680 hsa-miR-548m hsa-miR-629* hsa-miR-3119 hsa-miR-192* hsa-miR-4273
    SwitchGear 3'UTR luciferase reporter plasmidOPN5 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat OPN5

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    Sino Biological Human cDNA Clone for OPN5
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    eBioscience FlowRNA Probe Sets ( VF6-14216) for OPN5 


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    OPN5_HUMAN, Q6U736: Membrane; Multi-pass membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with OPN5           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for OPN5 About    
    See pathways by source

    SuperPathContained pathways About
    1Signaling by GPCR
    Signaling by GPCR0.90
    Signal Transduction0.58
    GPCR downstream signaling0.90
    2Peptide ligand-binding receptors
    Class A/1 (Rhodopsin-like receptors)0.71
    G alpha (i) signalling events0.44
    GPCR ligand binding0.71
    3Opsins
    Opsins


    Find genes that share SuperPaths with OPN5           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    2 Reactome Pathways for OPN5
        G alpha (i) signalling events
    Opsins


        Pathway & Disease-focused RT2 Profiler PCR Array including OPN5: 
              G Protein Coupled Receptors 384HT in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for OPN5

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007186G-protein coupled receptor signaling pathway ----
    GO:0007601visual perception IEA--
    GO:0007602phototransduction IEA--
    GO:0018298protein-chromophore linkage IEA--

    Find genes that share ontologies with OPN5           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for OPN5



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for OPN5 gene (2 alternative transcripts): 
    NM_181744.3  NM_001030051.1  

    Unigene Cluster for OPN5:

    Opsin 5
    Hs.213717  [show with all ESTs]
    Unigene Representative Sequence: NR_033806
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000489301 ENST00000371211 ENST00000393699 ENST00000244799(uc003ozc.3 uc003ozd.3)
    ENST00000510695
    miRNA
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    Block miRNA regulation of human, mouse, rat OPN5 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate OPN5 (see all 18):
    hsa-miR-448 hsa-miR-513a-5p hsa-miR-3680 hsa-miR-548m hsa-miR-629* hsa-miR-3119 hsa-miR-192* hsa-miR-4273
    SwitchGear 3'UTR luciferase reporter plasmidOPN5 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat OPN5
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: OPN5 (NM_181744)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OPN5
    Primer
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    OriGene qPCR primer pairs and template standards for OPN5
    OriGene qSTAR qPCR primer pairs in human, mouse for OPN5
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat OPN5
      QuantiTect SYBR Green Assays in human, mouse, rat OPN5
      QuantiFast Probe-based Assays in human, mouse, rat OPN5
    Flow Cytometry
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    eBioscience FlowRNA Probe Sets ( VF6-14216) for OPN5 

    Additional mRNA sequence: 

    AY255615.1 AY288419.1 AY377391.1 BC042544.1 BC126194.1 BC126198.1 BX647224.1 NR_033806.1 

    3 DOTS entries:

    DT.75191000  DT.101977807  DT.99930927 

    10 AceView cDNA sequences:

    NM_181744 AY288419 BX647224 AY377391 AY255615 AA232919 BC042544 AI810121 
    AI910964 BG721121 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for OPN5    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b
    SP1:              -     -                       -                                       
    SP2:                                                                                    
    SP3:              -     -     -                 -                                       
    SP4:                                                                                    
    SP5:                    -                                                               


    ECgene alternative splicing isoforms for OPN5

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    OPN5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTGACACTCA
    OPN5 Expression
    About this image

    OPN5 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    OPN5 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.213717

    UniProtKB/Swiss-Prot: OPN5_HUMAN, Q6U736
    Tissue specificity: Detected in brain and retina and cell lines derived from neural retina

        Pathway & Disease-focused RT2 Profiler PCR Array including OPN5: 
              G Protein Coupled Receptors 384HT in human mouse rat

    Primer
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for OPN5 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Opn51 , 5 opsin 51, 5 89.96(n)1
    95.74(a)1
      17 (19.65 cM)5
    3533441  NM_181753.41  NP_861418.21 
     425567835 
    chicken
    (Gallus gallus)
    Aves OPN51 opsin 5 74.95(n)
    78.32(a)
      428670  NM_001130743.1  NP_001124215.1 
    lizard
    (Anolis carolinensis)
    Reptilia OPN56
    opsin 5
    73(a)
    1 ↔ 1
    1(138082326-138122701)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia opn51 opsin 5 72.9(n)
    75.67(a)
      100497642  XM_002935990.2  XP_002936036.1 
    zebrafish
    (Danio rerio)
    Actinopterygii opn51 opsin 5 67.15(n)
    67.53(a)
      564181  NM_001200046.1  NP_001186975.1 


    ENSEMBL Gene Tree for OPN5 (if available)
    TreeFam Gene Tree for OPN5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for OPN5 gene
    OPN32  RGR2  OPN1MW22  OPN42  OPN1LW2  OPN1MW2  OPN1SW2  RHO2  
    RRH2  
    3 SIMAP similar genes for OPN5 using alignment to 3 protein entries:     OPN5_HUMAN (see all proteins):
    RRH    OPN3    OPN4

    Find genes that share paralogs with OPN5           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for OPN5 (see all 941)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs604969691,2
    C--47662766(+) TACTA-/AGACCTGT 1 -- us2k11Minor allele frequency- AGA:0.00NA 2
    rs1486151231,2
    C--47747954(+) GCTATA/GTCTTG 1 -- us2k10--------
    rs1896870881,2
    --47747991(+) AGCATC/TTCAGC 1 -- us2k10--------
    rs121747501,2
    C,F,A,H--47748009(+) AAATAA/TACAGG 1 -- us2k114Minor allele frequency- T:0.27NS EA WA NA CSA 636
    rs1827088991,2
    --47748032(+) TAATAC/TGCTTT 1 -- us2k10--------
    rs1442754181,2
    --47748045(+) AGTCCA/GATATC 1 -- us2k10--------
    rs18900631,2
    C,F,O,A,H--47748241(+) TTGGGC/TGGGGG 1 -- us2k122Minor allele frequency- T:0.30MN NS EA NA WA CSA 2529
    rs1870364451,2
    C--47748288(+) GGCAGA/TCAAAG 1 -- us2k10--------
    rs715684301,2
    C,F--47748572(+) TTACAC/TGGTTA 1 -- us2k12Minor allele frequency- T:0.50NA 4
    rs1915171371,2
    --47748597(+) ACCCTC/GTCACC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for OPN5 (47749718 - 47800516 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for OPN5:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv269317CNV Insertion20981092

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing OPN5
    DNA2.0 Custom Variant and Variant Library Synthesis for OPN5

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609042    OMIM disorders: --


    Find genes that share disorders with OPN5           About GenesLikeMe

    Genetic Association Database (GAD): OPN5

    Export disorders for OPN5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for OPN5 gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with OPN5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Neuropsin (Opn5): a novel opsin identified in mammalian neural tissue. (PubMed id 14623103)1, 2, 3 Tarttelin E.E.... Lucas R.J. (FEBS Lett. 2003)
    2. Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives. (PubMed id 14623098)1, 2, 3 Fredriksson R....Schioeth H.B. (FEBS Lett. 2003)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (Nature 2003)
    5. The G protein-coupled receptor repertoires of human and mouse. (PubMed id 12679517)1, 2 Vassilatis D.K.... Gaitanaris G.A. (Proc. Natl. Acad. Sci. U.S.A. 2003)
    6. UV-sensitive photoreceptor protein OPN5 in humans and mice. (PubMed id 22043319)1 Kojima D....Fukada Y. (PLoS ONE 2011)
    7. Genetic variations of human neuropsin gene and psychiatric disorders: polymorphism screening and possible association with bipolar disorder and cognitive functions. (PubMed id 18354391)1 Izumi A....Kunugi H. (Neuropsychopharmacology 2008)
    8. Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors. (PubMed id 18240029)1 Luttrell L.M. (Mol. Biotechnol. 2008)
    9. Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study. (PubMed id 17903295)4 Lunetta K.L....Murabito J.M. (BMC Med. Genet. 2007)
    10. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 221391 HGNC: 19992 AceView: OPN5 Ensembl:ENSG00000124818 euGenes: HUgn221391
    ECgene: OPN5 H-InvDB: OPN5

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for OPN5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for OPN5 gene:
    Search GeneIP for patents involving OPN5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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