Aliases for OPN1MW2 Gene
External Ids for OPN1MW2 Gene
Previous GeneCards Identifiers for OPN1MW2 Gene
This gene encodes for a light absorbing visual pigment of the opsin gene family. The encoded protein is called green cone photopigment or medium-wavelength sensitive opsin. Opsins are G-protein coupled receptors with seven transmembrane domains, an N-terminal extracellular domain, and a C-terminal cytoplasmic domain. The long-wavelength opsin gene and multiple copies of the medium-wavelength opsin gene are tandemly arrayed on the X chromosome and frequent unequal recombination and gene conversion may occur between these sequences. X chromosomes may have fusions of the medium- and long-wavelength opsin genes or may have more than one copy of these genes. Defects in this gene are the cause of deutanopic colorblindness. [provided by RefSeq, Mar 2009]
GeneCards Summary for OPN1MW2 Gene
OPN1MW2 (Opsin 1 (Cone Pigments), Medium-Wave-Sensitive 2) is a Protein Coding gene. Diseases associated with OPN1MW2 include blue cone monochromacy and thyroid hormone resistance. Among its related pathways are Signaling by GPCR and Disease. GO annotations related to this gene include G-protein coupled receptor activity and photoreceptor activity. An important paralog of this gene is OPN1SW.
UniProtKB/Swiss-Prot for OPN1MW2 Gene
Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal