Aliases for OPN1MW2 Gene
External Ids for OPN1MW2 Gene
Previous GeneCards Identifiers for OPN1MW2 Gene
This gene encodes for a light absorbing visual pigment of the opsin gene family. The encoded protein is called green cone photopigment or medium-wavelength sensitive opsin. Opsins are G-protein coupled receptors with seven transmembrane domains, an N-terminal extracellular domain, and a C-terminal cytoplasmic domain. The long-wavelength opsin gene and multiple copies of the medium-wavelength opsin gene are tandemly arrayed on the X chromosome and frequent unequal recombination and gene conversion may occur between these sequences. X chromosomes may have fusions of the medium- and long-wavelength opsin genes or may have more than one copy of these genes. Defects in this gene are the cause of deutanopic colorblindness. [provided by RefSeq, Mar 2009]
GeneCards Summary for OPN1MW2 Gene
OPN1MW2 (Opsin 1 (Cone Pigments), Medium-Wave-Sensitive 2) is a Protein Coding gene. Diseases associated with OPN1MW2 include blue cone monochromacy and achromatopsia. Among its related pathways are Signaling by GPCR and Downstream signaling events of B Cell Receptor (BCR). GO annotations related to this gene include G-protein coupled receptor activity and photoreceptor activity. An important paralog of this gene is OPN1SW.
UniProtKB/Swiss-Prot for OPN1MW2 Gene
Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal