Aliases for OPN1LW Gene
External Ids for OPN1LW Gene
Previous HGNC Symbols for OPN1LW Gene
Previous GeneCards Identifiers for OPN1LW Gene
This gene encodes for a light absorbing visual pigment of the opsin gene family. The encoded protein is called red cone photopigment or long-wavelength sensitive opsin. Opsins are G-protein coupled receptors with seven transmembrane domains, an N-terminal extracellular domain, and a C-terminal cytoplasmic domain. This gene and the medium-wavelength opsin gene are tandemly arrayed on the X chromosome and frequent unequal recombination and gene conversion may occur between these sequences. X chromosomes may have fusions of the medium- and long-wavelength opsin genes or may have more than one copy of these genes. Defects in this gene are the cause of partial, protanopic colorblindness. [provided by RefSeq, Jul 2008]
GeneCards Summary for OPN1LW Gene
OPN1LW (Opsin 1 (Cone Pigments), Long-Wave-Sensitive) is a Protein Coding gene. Diseases associated with OPN1LW include Colorblindness, Protan and Blue Cone Monochromacy. Among its related pathways are Metabolism of fat-soluble vitamins and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and photoreceptor activity. An important paralog of this gene is OPN1MW.
UniProtKB/Swiss-Prot for OPN1LW Gene
Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.