Aliases for OPN1LW Gene
External Ids for OPN1LW Gene
Previous HGNC Symbols for OPN1LW Gene
Previous GeneCards Identifiers for OPN1LW Gene
This gene encodes for a light absorbing visual pigment of the opsin gene family. The encoded protein is called red cone photopigment or long-wavelength sensitive opsin. Opsins are G-protein coupled receptors with seven transmembrane domains, an N-terminal extracellular domain, and a C-terminal cytoplasmic domain. This gene and the medium-wavelength opsin gene are tandemly arrayed on the X chromosome and frequent unequal recombination and gene conversion may occur between these sequences. X chromosomes may have fusions of the medium- and long-wavelength opsin genes or may have more than one copy of these genes. Defects in this gene are the cause of partial, protanopic colorblindness. [provided by RefSeq, Jul 2008]
GeneCards Summary for OPN1LW Gene
OPN1LW (Opsin 1 (Cone Pigments), Long-Wave-Sensitive) is a Protein Coding gene. Diseases associated with OPN1LW include colorblindness, protan and blue cone monochromacy. Among its related pathways are Signaling by GPCR and Infectious disease. GO annotations related to this gene include G-protein coupled receptor activity and photoreceptor activity. An important paralog of this gene is OPN1SW.
UniProtKB/Swiss-Prot for OPN1LW Gene
Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.