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OPALIN Gene

protein-coding   GIFtS: 48
GCID: GC10M098093

Oligodendrocytic Myelin Paranodal And Inner Loop Protein

(Previous name: transmembrane protein 10)
(Previous symbol: TMEM10)
  See OPALIN-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Oligodendrocytic Myelin Paranodal And Inner Loop Protein1 2 3     TMP102
Transmembrane Protein 101 2 3     opalin2
TMEM101 2 3     Transmembrane Protein TMP102
HTMP102 3     

External Ids:    HGNC: 207071   Entrez Gene: 933772   Ensembl: ENSG000001974307   UniProtKB: Q96PE53   

Export aliases for OPALIN gene to outside databases

Previous GC identifer: GC10M091730


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for OPALIN Gene:
OPALIN (oligodendrocytic myelin paranodal and inner loop protein) is a protein-coding gene. Diseases associated with OPALIN include fucosidosis.

Gene Wiki entry for OPALIN (TMEM10) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000010.10  NC_018921.2  NT_030059.14  
Regulatory elements:
   Regulatory transcription factor binding sites in the OPALIN gene promoter:
         Max1   STAT1   AML1a   GCNF   STAT1beta   CUTL1   STAT1alpha   YY1   COMP1   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidOPALIN promoter sequence
   Search Chromatin IP Primers for OPALIN

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat OPALIN


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q23-q24   Ensembl cytogenetic band:  10q24.1   HGNC cytogenetic band: 10q23-q24

OPALIN Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
OPALIN gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M098093:  view genomic region     (about GC identifiers)

Start:
98,102,973 bp from pter      End:
98,119,092 bp from pter
Size:
16,120 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: OPALI_HUMAN, Q96PE5 (See protein sequence)
Recommended Name: Opalin  
Size: 141 amino acids; 15683 Da
Secondary accessions: A8MYG4 B4DK96 Q5W102
Alternative splicing: 3 isoforms:  Q96PE5-1   Q96PE5-2   Q96PE5-3   (No experimental confirmation available. Gene prediction based on EST data)

Explore the universe of human proteins at neXtProt for OPALIN: NX_Q96PE5

Explore proteomics data for OPALIN at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn6, Asn12, Thr14
  • Modification sites at PhosphoSitePlus

  • See OPALIN Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (10 alternative transcripts): 
    NP_001035191.1  NP_001035192.1  NP_001271249.1  NP_001271250.1  NP_001271251.1  NP_001271252.1  NP_001271253.1  NP_001271255.1  
    NP_001271256.1  NP_149984.1  

    ENSEMBL proteins: 
     ENSP00000360214   ENSP00000377449   ENSP00000377448   ENSP00000398025   ENSP00000445125  

    OPALIN Human Recombinant Protein Products:

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    Sino Biological Recombinant Protein for OPALIN
    Sino Biological Cell Lysate for OPALIN
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    Cloud-Clone Corp. Proteins for OPALIN

     
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    OPALIN Antibody Products:

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    Abcam antibodies for OPALIN
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    OPALIN Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. CLIAs for OPALIN
    Search eBioscience for ELISAs for OPALIN 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR026609 Opalin

    Graphical View of Domain Structure for InterPro Entry Q96PE5

    ProtoNet protein and cluster: Q96PE5


    Find genes that share domains with OPALIN           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Phenotypes:
         1 GenomeRNAi human phenotype for OPALIN:
     Decreased Wnt reporter activit 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for OPALIN
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for OPALIN

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for OPALIN
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for OPALIN

    miRNA
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    Block miRNA regulation of human, mouse, rat OPALIN using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate OPALIN (see all 10):
    hsa-miR-576-5p hsa-miR-125a-5p hsa-miR-4297 hsa-miR-4263 hsa-miR-3653 hsa-miR-3658 hsa-miR-125b hsa-miR-330-3p
    SwitchGear 3'UTR luciferase reporter plasmidOPALIN 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Predesigned siRNA for gene silencing in human, mouse, rat OPALIN

    Gene Editing
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    Clone
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    OriGene ORF clones in mouse, rat for OPALIN
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): OPALIN (NM_001040102)
    Sino Biological Human cDNA Clone for OPALIN
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for OPALIN
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OPALIN

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OPALIN


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    OPALI_HUMAN, Q96PE5: Cell membrane; Single-pass type I membrane protein. Note=In the CNS, enriched in the myelin
    paranodal and inner loop membranes, but not that of the PNS (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    golgi apparatus4
    cytosol1
    endoplasmic reticulum1
    extracellular1
    nucleus1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005794Golgi apparatus IDA--
    GO:0005886plasma membrane IEA--
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with OPALIN           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for OPALIN
    Interactions:

        Search GeneGlobe Interaction Network for OPALIN

    3 Interacting proteins for OPALIN (Q96PE53) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CALM1P621583I2D: score=1 
    CALM2P621583I2D: score=1 
    CALM3P621583I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for OPALIN (OPALI)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for OPALIN gene (10 alternative transcripts): 
    NM_001040102.2  NM_001040103.2  NM_001284320.1  NM_001284321.1  NM_001284322.1  NM_001284323.1  NM_001284324.1  NM_001284326.1  
    NM_001284327.1  NM_033207.4  

    Unigene Cluster for OPALIN:

    Oligodendrocytic myelin paranodal and inner loop protein
    Hs.12449  [show with all ESTs]
    Unigene Representative Sequence: NM_001040103
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000371172 ENST00000393871(uc001kmk.3) ENST00000393870 ENST00000419479(uc010qor.2 uc001kmi.3 uc001kmj.3 uc010qos.2 uc009xve.1)
    ENST00000536387
    miRNA
    Products:
         
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    Selected qRT-PCR Assays for microRNAs that regulate OPALIN (see all 10):
    hsa-miR-576-5p hsa-miR-125a-5p hsa-miR-4297 hsa-miR-4263 hsa-miR-3653 hsa-miR-3658 hsa-miR-125b hsa-miR-330-3p
    SwitchGear 3'UTR luciferase reporter plasmidOPALIN 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for OPALIN
    Predesigned siRNA for gene silencing in human, mouse, rat OPALIN
    Clone
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    OriGene clones in human, mouse for OPALIN (see all 16)
    OriGene ORF clones in mouse, rat for OPALIN
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): OPALIN (NM_001040102)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for OPALIN
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OPALIN
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for OPALIN
    OriGene qSTAR qPCR primer pairs in human, mouse for OPALIN
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat OPALIN
      QuantiTect SYBR Green Assays in human, mouse, rat OPALIN
      QuantiFast Probe-based Assays in human, mouse, rat OPALIN

    Additional mRNA sequence: 

    AF367761.2 AK289835.1 AK296462.1 AK296562.1 AK309095.1 AK311260.1 AK316090.1 AL834229.1 
    BC024191.1 BC033737.1 

    5 DOTS entries:

    DT.40108176  DT.121253618  DT.100649464  DT.121253610  DT.121253597 

    Selected AceView cDNA sequences (see all 40):

    AL834229 F11129 BP348941 BC033737 F13555 CK023662 NM_033207 BP349325 
    BP362253 BP360708 BI599828 BC024191 BX423903 BX107871 Z42095 BI548105 
    BX422994 BI596691 BI548014 N95690 AF367761 N63401 BM922120 BI819563 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for OPALIN (see all 6)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7 ^ 8a · 8b · 8c · 8d · 8e
    SP1:              -     -     -     -     -           -                                             
    SP2:                                      -                 -                                       
    SP3:              -     -     -     -     -                 -                                       
    SP4:                    -     -     -     -                 -                                       
    SP5:                                                        -                                       


    ECgene alternative splicing isoforms for OPALIN

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    OPALIN expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAGCTATAAA
    OPALIN Expression
    About this image


    OPALIN expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Brain (Nervous System)
             Myelinating Oligodendrocyte Cells Forebrain White Matter
    OPALIN Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    OPALIN Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.12449

    UniProtKB/Swiss-Prot: OPALI_HUMAN, Q96PE5
    Tissue specificity: Brain specific

        Custom PCR Arrays for OPALIN
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OPALIN

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of human and mouse.

    Orthologs for OPALIN gene from Selected species (see all 6)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Opalin1 , 5 oligodendrocytic myelin paranodal and inner loop protein1, 5 78.96(n)1
    78.01(a)1
      19 (34.36 cM)5
    2261151  NM_153520.11  NP_705740.11 
     410634205 


    ENSEMBL Gene Tree for OPALIN (if available)
    TreeFam Gene Tree for OPALIN (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for OPALIN (see all 397)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1475120191,2
    --98102532(+) TATCTC/GTCTCC 3 -- ds50010--------
    rs1400330621,2
    --98102555(+) AGGAAC/GTGAGA 3 -- ds50010--------
    rs28615741,2
    C,F,A,H--98102782(+) CCCTGG/CGTTAG 3 -- ds50018Minor allele frequency- C:0.21NS EA CSA NA 625
    rs1895112931,2
    --98102787(+) GGTTAA/GGGAAG 3 -- ds50010--------
    rs1818141471,2
    --98102937(+) AGCCAA/GTGTTC 3 -- ds50010--------
    rs19516281,2
    H--98102948(-) CCTATA/GTTAGA 3 -- ds50014Minor allele frequency- G:0.00NS EA 406
    rs1441178661,2
    --98102950(+) TAATAC/TAGGCA 3 -- ds50010--------
    rs118183911,2
    C,F,H--98103111(+) AAGCCG/ATGGAT 3 -- ut31 ese36Minor allele frequency- A:0.01NS EA NA WA 534
    rs1852079401,2
    --98103175(+) AGCTAC/TATGGC 3 -- ut310--------
    rs1135942391,2
    C--98103215(+) TACAAC/TCACCC 3 -- ut310--------

    HapMap Linkage Disequilibrium report for OPALIN (98102973 - 98119092 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for OPALIN:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv831949CNV Gain17160897
    nsv831950CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing OPALIN
    DNA2.0 Custom Variant and Variant Library Synthesis for OPALIN

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    1 disease for OPALIN:    
    About MalaCards
    fucosidosis

    1 disease from the University of Copenhagen DISEASES database for OPALIN:
    Fucosidosis

    Find genes that share disorders with OPALIN           About GenesLikeMe


    Export disorders for OPALIN gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for OPALIN gene, integrated from 10 sources (see all 17):
    (articles sorted by number of sources associating them with OPALIN)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and characterization of a novel human brain-specific gene, homologous to S. scrofa tmp83.5, in the chromosome 10q24 critical region for temporal lobe epilepsy and spastic paraplegia. (PubMed id 11814680)1, 2, 3 Nobile C.... Michelucci R. (Gene 2002)
    2. An oligodendrocyte enhancer in a phylogenetically conserved intron region of the mammalian myelin gene Opalin. (PubMed id 17442045)1, 3 Aruga J....Furuichi T. (J. Neurochem. 2007)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Opalin, a transmembrane sialylglycoprotein located in the central nervous system myelin paranodal loop membrane. (PubMed id 18490449)1 Yoshikawa F....Furuichi T. (J. Biol. Chem. 2008)
    5. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    6. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    7. The LIFEdb database in 2006. (PubMed id 16381901)1 Mehrle A....Wiemann S. (Nucleic Acids Res. 2006)
    8. Scanning the human proteome for calmodulin-binding proteins. (PubMed id 15840729)1 Shen X....Liu R. (Proc. Natl. Acad. Sci. U.S.A. 2005)
    9. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PubMed id 15342556)1 Suzuki Y.... Sugano S. (Genome Res. 2004)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 93377 HGNC: 20707 AceView: TMEM10 Ensembl:ENSG00000197430 euGenes: HUgn93377
    ECgene: OPALIN H-InvDB: OPALIN

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for OPALIN Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for OPALIN gene:
    Search GeneIP for patents involving OPALIN

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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