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Aliases for OOSP2 Gene

Aliases for OOSP2 Gene

  • Oocyte Secreted Protein 2 2 3
  • Placenta-Specific 1-Like Protein 3 4
  • Transmembrane Protein 122 2 3
  • TMEM122 3 4
  • PLAC1L 3 4
  • Placenta-Specific 1-Like 2
  • Protein TMEM122 4

External Ids for OOSP2 Gene

Previous HGNC Symbols for OOSP2 Gene

  • TMEM122
  • PLAC1L

Previous GeneCards Identifiers for OOSP2 Gene

  • GC11P059808

Summaries for OOSP2 Gene

GeneCards Summary for OOSP2 Gene

OOSP2 (Oocyte Secreted Protein 2) is a Protein Coding gene. An important paralog of this gene is PLAC1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OOSP2 Gene

Genomics for OOSP2 Gene

Genomic Location for OOSP2 Gene

60,040,275 bp from pter
60,048,044 bp from pter
7,770 bases
Plus strand

Genomic View for OOSP2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OOSP2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OOSP2 Gene

No data available for Regulatory Elements for OOSP2 Gene

Proteins for OOSP2 Gene

  • Protein details for OOSP2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Oocyte-secreted protein 2
    Protein Accession:
    Secondary Accessions:
    • E9PJA4
    • Q8N9U6

    Protein attributes for OOSP2 Gene

    158 amino acids
    Molecular mass:
    17971 Da
    Quaternary structure:
    No Data Available
    • Sequence=AP000790; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for OOSP2 Gene

Proteomics data for OOSP2 Gene at MOPED

Post-translational modifications for OOSP2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for OOSP2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for OOSP2 Gene

Domains & Families for OOSP2 Gene

Protein Domains for OOSP2 Gene


Suggested Antigen Peptide Sequences for OOSP2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the PLAC1 family.
  • Belongs to the PLAC1 family.
genes like me logo Genes that share domains with OOSP2: view

No data available for Gene Families for OOSP2 Gene

Function for OOSP2 Gene

Phenotypes for OOSP2 Gene

genes like me logo Genes that share phenotypes with OOSP2: view

miRNA for OOSP2 Gene

miRTarBase miRNAs that target OOSP2

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OOSP2

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for OOSP2 Gene

Localization for OOSP2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OOSP2 Gene


Gene Ontology (GO) - Cellular Components for OOSP2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with OOSP2: view

No data available for Subcellular locations from COMPARTMENTS for OOSP2 Gene

Pathways & Interactions for OOSP2 Gene

SuperPathways for OOSP2 Gene

No Data Available

Interacting Proteins for OOSP2 Gene

Gene Ontology (GO) - Biological Process for OOSP2 Gene


No data available for Pathways by source and SIGNOR curated interactions for OOSP2 Gene

Drugs & Compounds for OOSP2 Gene

No Compound Related Data Available

Transcripts for OOSP2 Gene

mRNA/cDNA for OOSP2 Gene

(1) REFSEQ mRNAs :
(18) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OOSP2 Gene

No ASD Table

Relevant External Links for OOSP2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OOSP2 Gene

mRNA expression in normal human tissues for OOSP2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for OOSP2 Gene

This gene is overexpressed in Testis (x52.4).
genes like me logo Genes that share expression patterns with OOSP2: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for OOSP2 Gene

Orthologs for OOSP2 Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for OOSP2 Gene

Organism Taxonomy Gene Similarity Type Details
(Mus musculus)
Mammalia Oosp2 35
  • 71.24 (n)
  • 55.56 (a)
Plac1l 16
Plac1l 36
  • 50 (a)
(Pan troglodytes)
Mammalia PLAC1L 35
  • 99.37 (n)
  • 98.73 (a)
OOSP2 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Oosp2 35
  • 68.64 (n)
  • 51.97 (a)
Species with no ortholog for OOSP2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OOSP2 Gene

Gene Tree for OOSP2 (if available)
Gene Tree for OOSP2 (if available)

Paralogs for OOSP2 Gene

Paralogs for OOSP2 Gene

genes like me logo Genes that share paralogs with OOSP2: view

Variants for OOSP2 Gene

Sequence variations from dbSNP and Humsavar for OOSP2 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs492674 -- 60,040,561(-) ATTAA(C/G)TCCTT intron-variant
rs526286 -- 60,046,309(-) AGCTT(G/T)GGGTA intron-variant
rs575699 -- 60,039,907(-) ATTCC(A/C)TCTCT upstream-variant-2KB
rs632649 -- 60,045,668(+) TTTGG(G/T)AAAAT intron-variant
rs637975 -- 60,040,323(-) ACAGG(A/G)TGCTC utr-variant-5-prime

Variation tolerance for OOSP2 Gene

Residual Variation Intolerance Score: 50.03% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.17; 23.64% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OOSP2 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for OOSP2 Gene

Disorders for OOSP2 Gene

Relevant External Links for OOSP2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with OOSP2: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OOSP2 Gene

Publications for OOSP2 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 67
  2. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PMID: 22990118) Woods N.T. … Monteiro A.N. (Sci Signal 2012) 67
  3. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 67
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67

Products for OOSP2 Gene

Sources for OOSP2 Gene

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