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Aliases for OOSP1 Gene

Aliases for OOSP1 Gene

  • Oocyte Secreted Protein 1, Pseudogene 2 3 5
  • Oocyte Secreted Protein 1 2

External Ids for OOSP1 Gene

Previous GeneCards Identifiers for OOSP1 Gene

  • GC11U901218
  • GC11P059705

Summaries for OOSP1 Gene

GeneCards Summary for OOSP1 Gene

OOSP1 (Oocyte Secreted Protein 1, Pseudogene) is a Pseudogene.

UniProtKB/Swiss-Prot for OOSP1 Gene

  • May be involved in cell differentiation.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OOSP1 Gene

Genomics for OOSP1 Gene

Regulatory Elements for OOSP1 Gene

Enhancers for OOSP1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11G059919 1 Ensembl ENCODE 0.4 -19.3 -19255 0.4 CTCF ZNF654 CBX3 ZNF384 REST ATF2 RAD21 CHAMP1 RFX5 FOSL1 TCN1 GIF OOSP2 MS4A2 OOSP1 SRD5A3P1
GH11G059959 1.1 ENCODE 0.3 +22.8 22757 2.7 PKNOX1 FOXA2 CREB3L1 ARNT ZNF766 CBX5 FOS REST ZNF592 MEF2D TMEM109 OOSP1 LOC105369444
GH11G059900 1.1 ENCODE 0.3 -37.0 -37045 1.0 HDGF PKNOX1 CREB3L1 MLX ARNT AGO1 ARID4B SIN3A YY1 SLC30A9 TCN1 MS4A2 SRD5A3P1 OOSP1
GH11G059968 1 FANTOM5 0.3 +29.8 29817 0.3 PKNOX1 ATF1 ARNT TCF12 ZNF766 ELK1 GATA2 NCOA1 REST MBD2 OOSP2 MS4A3 MS4A2 MRPL16 OOSP1 LOC105369444
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around OOSP1 on UCSC Golden Path with GeneCards custom track

Genomic Location for OOSP1 Gene

Chromosome:
11
Start:
59,938,455 bp from pter
End:
59,995,845 bp from pter
Size:
57,391 bases
Orientation:
Plus strand

Genomic View for OOSP1 Gene

Genes around OOSP1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OOSP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OOSP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OOSP1 Gene

Proteins for OOSP1 Gene

  • Protein details for OOSP1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A8MZH6-OOSP1_HUMAN
    Recommended name:
    Putative oocyte-secreted protein 1 homolog
    Protein Accession:
    A8MZH6

    Protein attributes for OOSP1 Gene

    Size:
    123 amino acids
    Molecular mass:
    14433 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OOSP1 Gene

Post-translational modifications for OOSP1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for OOSP1 Gene

Domains & Families for OOSP1 Gene

Protein Domains for OOSP1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for OOSP1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A8MZH6

UniProtKB/Swiss-Prot:

OOSP1_HUMAN :
  • Belongs to the PLAC1 family.
Family:
  • Belongs to the PLAC1 family.
genes like me logo Genes that share domains with OOSP1: view

No data available for Gene Families for OOSP1 Gene

Function for OOSP1 Gene

Molecular function for OOSP1 Gene

UniProtKB/Swiss-Prot Function:
May be involved in cell differentiation.

Phenotypes for OOSP1 Gene

GenomeRNAi human phenotypes for OOSP1:
genes like me logo Genes that share phenotypes with OOSP1: view

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OOSP1 Gene

Localization for OOSP1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OOSP1 Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OOSP1 gene
Compartment Confidence
extracellular 4
nucleus 2
cytosol 2

Gene Ontology (GO) - Cellular Components for OOSP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with OOSP1: view

Pathways & Interactions for OOSP1 Gene

SuperPathways for OOSP1 Gene

No Data Available

Interacting Proteins for OOSP1 Gene

Gene Ontology (GO) - Biological Process for OOSP1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for OOSP1 Gene

Transcripts for OOSP1 Gene

mRNA/cDNA for OOSP1 Gene

(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OOSP1 Gene

No ASD Table

Relevant External Links for OOSP1 Gene

GeneLoc Exon Structure for
OOSP1
ECgene alternative splicing isoforms for
OOSP1

Expression for OOSP1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OOSP1 Gene

NURSA nuclear receptor signaling pathways regulating expression of OOSP1 Gene:

OOSP1

SOURCE GeneReport for Unigene cluster for OOSP1 Gene:

Hs.722773
genes like me logo Genes that share expression patterns with OOSP1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OOSP1 Gene

Orthologs for OOSP1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OOSP1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia OOSP1 35
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia OOSP1 35
  • 45 (a)
OneToOne
cow
(Bos Taurus)
Mammalia OOSP1 35
  • 44 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Oosp1 35
  • 30 (a)
OneToOne
Species where no ortholog for OOSP1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OOSP1 Gene

ENSEMBL:
Gene Tree for OOSP1 (if available)
TreeFam:
Gene Tree for OOSP1 (if available)

Paralogs for OOSP1 Gene

No data available for Paralogs for OOSP1 Gene

Variants for OOSP1 Gene

Sequence variations from dbSNP and Humsavar for OOSP1 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1000015532 -- 59,949,007(+) TTTAT(A/G)AATAA intron-variant
rs1000034477 -- 59,993,246(+) TGGTA(C/T)CAATT intron-variant
rs1000090076 -- 59,986,581(+) TCTTG(A/G)TTGAC intron-variant
rs1000124571 -- 59,968,912(+) TTGGC(G/T)TCAGG intron-variant
rs1000134920 -- 59,942,927(+) ACCCC(A/G)ATGAA nc-transcript-variant

Variation tolerance for OOSP1 Gene

Gene Damage Index Score: 0.54; 11.62% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OOSP1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OOSP1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for OOSP1 Gene

Disorders for OOSP1 Gene

Relevant External Links for OOSP1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OOSP1

No disorders were found for OOSP1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OOSP1 Gene

Publications for OOSP1 Gene

  1. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 3 4 64
  2. Oosp1 encodes a novel mouse oocyte-secreted protein. (PMID: 11747200) Yan C. … Matzuk M.M. (Genesis 2001) 2 3 64

Products for OOSP1 Gene

Sources for OOSP1 Gene

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