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Aliases for OOEP Gene

Aliases for OOEP Gene

  • Oocyte Expressed Protein 2 3
  • KHDC2 3 4 6
  • KH Homology Domain-Containing Protein 2 3 4
  • Oocyte Expressed Protein Homolog (Dog) 2 3
  • Oocyte- And Embryo-Specific Protein 19 3 4
  • KH Homology Domain Containing 2 2 3
  • C6orf156 3 4
  • HOEP19 3 4
  • Chromosome 6 Open Reading Frame 156 2
  • Oocyte-Expressed Protein Homolog 3
  • Oocyte And Embryo Protein 19 3
  • FLOPED 3
  • OEP19 4

External Ids for OOEP Gene

Previous Symbols for OOEP Gene

  • C6orf156

Summaries for OOEP Gene

GeneCards Summary for OOEP Gene

OOEP (Oocyte Expressed Protein) is a Protein Coding gene. GO annotations related to this gene include RNA binding. An important paralog of this gene is KHDC3L.

UniProtKB/Swiss-Prot for OOEP Gene

  • As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OOEP Gene

Genomics for OOEP Gene

Genomic Location for OOEP Gene

Start:
73,368,555 bp from pter
End:
73,395,133 bp from pter
Size:
26,579 bases
Orientation:
Minus strand

Genomic View for OOEP Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OOEP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OOEP Gene

Regulatory Elements for OOEP Gene

Proteins for OOEP Gene

  • Protein details for OOEP Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NGQ2-OOEP_HUMAN
    Recommended name:
    Oocyte-expressed protein homolog
    Protein Accession:
    A6NGQ2
    Secondary Accessions:
    • A6NIN5
    • A9UIB7

    Protein attributes for OOEP Gene

    Size:
    149 amino acids
    Molecular mass:
    17170 Da
    Quaternary structure:
    • Component of the SCMC which also includes at least NLRP5 and TLE6.

neXtProt entry for OOEP Gene

Proteomics data for OOEP Gene at MOPED

Post-translational modifications for OOEP Gene

No Post-translational modifications

Other Protein References for OOEP Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for OOEP Gene

Domains for OOEP Gene

Protein Domains for OOEP Gene

ProtoNet:

Suggested Antigen Peptide Sequences for OOEP Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A6NGQ2

UniProtKB/Swiss-Prot:

OOEP_HUMAN
Domain:
  • Contains an atypical KH domain with amino acid changes at critical sites, suggesting that it may not bind RNA:
    • A6NGQ2
  • Contains 1 KH domain.:
    • A6NGQ2
Family:
  • Belongs to the KHDC1 family.:
    • A6NGQ2
genes like me logo Genes that share domains with OOEP: view

No data available for Gene Families for OOEP Gene

Function for OOEP Gene

Molecular function for OOEP Gene

UniProtKB/Swiss-Prot Function: As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions.

Gene Ontology (GO) - Molecular Function for OOEP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003723 RNA binding IEA --
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with OOEP: view

Phenotypes for OOEP Gene

genes like me logo Genes that share phenotypes with OOEP: view

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OOEP Gene

Localization for OOEP Gene

Subcellular locations from UniProtKB/Swiss-Prot for OOEP Gene

Cytoplasm. Note=In the subcortical cytoplasm of early embryos from the 1-cell to the blastocyst stages. From the 2-cell stage, still detected in the subcortex, but excluded from cell-cell contact regions (By similarity). {ECO:0000250}.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OOEP Gene COMPARTMENTS Subcellular localization image for OOEP gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1

Gene Ontology (GO) - Cellular Components for OOEP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005938 cell cortex IEA --
GO:0043234 protein complex IEA --
GO:0045177 apical part of cell IEA --
genes like me logo Genes that share ontologies with OOEP: view

Pathways for OOEP Gene

SuperPathways for OOEP Gene

No Data Available

Interacting Proteins for OOEP Gene

Gene Ontology (GO) - Biological Process for OOEP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001701 in utero embryonic development IEA --
GO:0006468 protein phosphorylation IEA --
GO:0007566 embryo implantation IEA --
GO:0009566 fertilization IEA --
GO:0009880 embryonic pattern specification IEA --
genes like me logo Genes that share ontologies with OOEP: view

No data available for Pathways by source for OOEP Gene

Transcripts for OOEP Gene

mRNA/cDNA for OOEP Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OOEP Gene

Oocyte expressed protein:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for OOEP Gene

No ASD Table

Relevant External Links for OOEP Gene

GeneLoc Exon Structure for
OOEP
ECgene alternative splicing isoforms for
OOEP

Expression for OOEP Gene

mRNA expression in normal human tissues for OOEP Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for OOEP Gene

This gene is overexpressed in Testis (31.3).

SOURCE GeneReport for Unigene cluster for OOEP Gene Hs.671212

genes like me logo Genes that share expressions with OOEP: view

No data available for Protein expression and mRNA Expression by UniProt/SwissProt for OOEP Gene

Orthologs for OOEP Gene

This gene was present in the common ancestor of mammals.

Orthologs for OOEP Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia OOEP 35
  • 99.33 (n)
  • 99.33 (a)
OOEP 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia OOEP 35
  • 77.38 (n)
  • 68.57 (a)
OOEP 36
  • 67 (a)
OneToOne
dog
(Canis familiaris)
Mammalia OOEP 35
  • 78.75 (n)
  • 71.81 (a)
OOEP 36
  • 72 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ooep 35
  • 68.21 (n)
  • 54.63 (a)
Ooep 16
Ooep 36
  • 39 (a)
OneToOne
Species with no ortholog for OOEP:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OOEP Gene

ENSEMBL:
Gene Tree for OOEP (if available)
TreeFam:
Gene Tree for OOEP (if available)

Paralogs for OOEP Gene

Paralogs for OOEP Gene

Selected SIMAP similar genes for OOEP Gene using alignment to 3 proteins:

Pseudogenes.org Pseudogenes for OOEP Gene

genes like me logo Genes that share paralogs with OOEP: view

Variants for OOEP Gene

Sequence variations from dbSNP and Humsavar for OOEP Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs472050 -- 73,371,774(+) AAATA(A/T)AAAAA upstream-variant-2KB
rs496530 - 73,369,301(+) TTTCG(A/G)CTAGG missense, reference
rs497243 -- 73,369,318(+) GAGTC(A/C)ACTAT reference, synonymous-codon
rs522858 -- 73,368,246(-) GTACT(G/T)TTGGG downstream-variant-500B
rs780291 -- 73,371,756(+) aaaaa(A/T)aaaaa upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OOEP Gene

Variant ID Type Subtype PubMed ID
nsv830693 CNV Loss 17160897

Relevant External Links for OOEP Gene

HapMap Linkage Disequilibrium report
OOEP

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OOEP Gene

Disorders for OOEP Gene

No disorders were found for OOEP Gene.

No data available for UniProtKB/Swiss-Prot for OOEP Gene

Publications for OOEP Gene

  1. Atypical structure and phylogenomic evolution of the new eutherian oocyte-and embryo-expressed KHDC1/DPPA5/ECAT1/OOEP gene family. (PMID: 17913455) Pierre A. … Monget P. (Genomics 2007) 2 3 4
  2. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 4
  3. The sequence of the human genome. (PMID: 11181995) Venter J.C. … Zhu X. (Science 2001) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for OOEP Gene

Sources for OOEP Gene

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