OMP Gene

Aliases
for OMP gene

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
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Previous GC identifers: GC11P079140 GC11P078352 GC11P077036 GC11P076540 GC11P076491

Summaries
for OMP gene

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Genomic Views
for OMP gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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SwitchGear Promoter luciferase reporter plasmid: OMP promoter sequence

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat OMP

OMP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)


GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P076813:  view genomic region     (about GC identifiers)

Proteins
for OMP gene

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, antibodies-online, and/or GeneTex,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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Explore the universe of human proteins at neXtProt for OMP: NX_P47874

OMP Human Recombinant Protein Products:

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	OriGene Purified Protein for OMP OriGene Protein Over-expression Lysate for OMP OriGene MassSpec for OMP OriGene Custom Protein Services for OMP
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	Novus Biologicals OMP Proteins Novus Biologicals OMP Lysates
	Sino Biological Recombinant Protein for OMP Browse Sino Biological Cell Lysates
	ProSpec Recombinant Protein for OMP
	Cloud-Clone Corp. Proteins for OMP
	Search eBioscience for Proteins for OMP
	Search GeneTex for Proteins for OMP
	antibodies-online proteins for OMP (7 products)
	antibodies-online peptides for OMP

OMP Antibody Products:

	EMD Millipore Mono- and Polyclonal Antibodies for the study of OMP
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	Novus Biologicals OMP Antibodies
	Abcam antibodies for OMP
	Cloud-Clone Corp. Antibodies for OMP
	ThermoFisher Antibodies for OMP
	antibodies-online antibodies for OMP (45 products)

OMP Assay Products:

	Browse Kits and Assays available from EMD Millipore
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	GenScript Custom Assay Services for OMP
	Browse Enzo Life Sciences for kits & assays
	Cloud-Clone Corp. ELISAs for OMP Cloud-Clone Corp. CLIAs for OMP
	Search eBioscience for ELISAs for OMP
	antibodies-online kits for OMP (6 products)

Domains /
Families
for OMP gene

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GenesLikeMe)
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ProtoNet protein and cluster: P47874

Find genes that share domains with OMP           About GenesLikeMe

Function
for OMP gene

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene, Sets of similar genes according to GenesLikeMe)
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     Gene Ontology (GO): 1 molecular function term:    About this table

(inferred from 9 alleles) (MGI details for Omp)

genOway: Develop your customized and physiologically relevant rodent model for OMP

miRNA Products:		Block miRNA regulation of human, mouse, rat OMP using miScript Target Protectors
		Search for qRT-PCR Assays for microRNAs that regulate OMP
		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for OMP
		Predesigned siRNA for gene silencing in human, mouse, rat OMP

Gene Editing Products:

DNA2.0 Custom Protein Engineering Service for OMP

Clone Products:		OriGene clones in human, mouse for OMP (see all 5) OriGene ORF clones in mouse, rat for OMP OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: OMP (NM_000095)
		Sino Biological Human cDNA Clone for OMP
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for OMP
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OMP

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for OMP
		Browse ESI BIO Cell Lines and PureStem Progenitors for OMP

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OMP

Localization
for OMP gene

(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene, Sets of similar genes according to GenesLikeMe)
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Gene Ontology (GO): 5 cellular component terms:    About this table

Pathways & Interactions
for OMP gene

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GenesLikeMe, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene, Sets of similar genes according to GenesLikeMe)
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Gene Ontology (GO): 4 biological process terms:    About this table

Drugs & Compounds
for OMP gene

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, Sets of similar genes according to GenesLikeMe)
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Transcripts
for OMP gene

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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Expression
for OMP gene

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GenesLikeMe, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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OMP expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: TACTTCCTCG

About this image

Primer Products:		OriGene qSTAR qPCR primer pairs in human, mouse for OMP
		Pre-validated RT2 qPCR Primer Assay in human, mouse, rat OMP
		QuantiTect SYBR Green Assays in human, mouse, rat OMP
		QuantiFast Probe-based Assays in human, mouse, rat OMP

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OMP

Orthologs
for OMP gene

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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Paralogs
for OMP gene

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68,Sets of similar genes according to GenesLikeMe)
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Genomic Variants
for OMP gene

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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2 SNPs for OMP    About this table

Genomic Data					Transcription Related Data				Allele Frequencies
SNP ID	Valid	Clinical significance	Chr 11 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	--	--	--	-1st2nd3rd	--	--	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd
rs22335481,2,4		--	--	see VAR_051255	2		mis4		0	--	--	--	--
rs22335461,2,4		--	--	see VAR_051254	2		mis4		0	--	--	--	--

HapMap Linkage Disequilibrium report for OMP (76813886 - 76814377 bp)

Structural Variations
     Database of Genomic Variants (DGV) 2 variations for OMP:    About this table    

Variant ID	Type	Subtype	PubMed ID
dgv1225n71	CNV	Loss	21882294
nsv825998	CNV	Gain	20364138

Human Gene Mutation Database (HGMD): OMP

Site Specific Mutation Identification with PCR Assays

Search QIAGEN SeqTarget long-range PCR primers for resequencing OMP

DNA2.0 Custom Variant and Variant Library Synthesis for OMP

Disorders / Diseases
for OMP gene

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB, Sets of similar genes according to GenesLikeMe)
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12 diseases for OMP

Selected Novoseek inferred disease relationships for OMP gene (see all 18)    About this table

Publications
for OMP gene

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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1. Human and rodent OMP genes: conservation of structural and regulatory motifs and cellular localization. (PubMed id 8034318)^{1, 2, 9} Buiakova O.I.... Margolis F.L. (Genomics 1994)
2. Human olfactory marker protein maps close to tyrosinase and is a candidate gene for Usher syndrome type I. (PubMed id 8499899)^{1, 3, 9} Evans K.L....Brown S.D. (Hum. Mol. Genet. 1993)
3. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)^{1, 4} Bailey S.D....Anand S. (Diabetes Care 2010)
4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S.... Malek J. (Genome Res. 2004)
5. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)¹ Talmud P.J.... . (Am. J. Hum. Genet. 2009)
6. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)¹ Lamesch P.... Vidal M. (Genomics 2007)
7. Identification of members of the Bex gene family as olfactory marker protein (OMP) binding partners. (PubMed id 12911636)¹ Behrens M....Margolis F.L. (J. Neurochem. 2003)
8. Olfactory marker protein (OMP) exhibits a beta-clam fold in solution: implications for target peptide interaction and olfactory signal transduction. (PubMed id 12054873)¹ Baldisseri D.M....Margolis F.L. (J. Mol. Biol. 2002)
9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
10. Olfactory marker protein (OMP) gene deletion causes altered physiological activity of olfactory sensory neurons. (PubMed id 8790421)¹ Buiakova O.I....Margolis F.L. (Proc. Natl. Acad. Sci. U.S.A. 1996)

External Searches for OMP gene

Genome Databases showing OMP gene

Other Databases showing OMP gene

Specialized Databases showing OMP gene

Products
for OMP gene

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, GeneTex, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from genOway)
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