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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

OMD Gene

protein-coding GIFtS: 56
GCID: GC09M095176

Osteomodulin

Alzheimer's & Parkinson's Diseases Congress

See related diseases
at

MalaCards

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

Aliases
osteomodulin¹ ²		SLRR2C² ³
Osteoadherin Proteoglycan¹ ²		KSPG Osteomodulin² ³
Keratan Sulfate Proteoglycan Osteomodulin² ³		Osteoadherin³
OSAD² ³

External Ids:	HGNC: 8134¹	Entrez Gene: 4958²	Ensembl: ENSG00000127083⁷	UniProtKB: Q99983³

Export aliases for OMD gene to outside databases

Previous GC identifers: GC09M086003 GC09M086904 GC09M088475 GC09M090517 GC09M092256 GC09M094216 GC09M064853

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for OMD Gene:

OMD (osteomodulin) is a protein-coding gene. Diseases associated with OMD include occult macular dystrophy, and meckel's diverticulum, and among its related super-pathways are Metabolism of carbohydrates and Keratan sulfate/keratin metabolism. An important paralog of this gene is PODN.

UniProtKB/Swiss-Prot: OMD_HUMAN, Q99983

Function: May be implicated in biomineralization processes. Has a function in binding of osteoblasts via the

alpha(V)beta(3)-integrin (By similarity)

Gene Wiki entry for OMD Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000009.11 NC_018920.2 NT_008470.19

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the OMD gene promoter:
AP-1 ATF-2 FOXO3 FOXO3b SRY POU2F1 POU2F1a FOXO3a c-Jun
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: OMD promoter sequence

Search SABiosciences Chromatin IP Primers for OMD

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OMD

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q22.31 Ensembl cytogenetic band: 9q22.31 HGNC cytogenetic band: 9q22.31

OMD Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
OMD gene location

GeneLoc information about chromosome 9 GeneLoc Exon Structure

GeneLoc location for GC09M095176: view genomic region (about GC identifiers)

Start:	95,176,527 bp from pter	End:	95,186,836 bp from pter
Size:	10,310 bases	Orientation:	minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: OMD_HUMAN, Q99983 (See protein sequence)

Recommended Name: Osteomodulin precursor

Size: 421 amino acids; 49492 Da

Subunit: Binds the alpha(V)beta(3)-integrin (By similarity)

Subcellular location: Secreted, extracellular space, extracellular matrix (By similarity)

Secondary accessions: Q5TBF4

Explore the universe of human proteins at neXtProt for OMD: NX_Q99983

Explore proteomics data for OMD at MOPED

Post-translational modifications:

UniProtKB: Binds keratan sulfate chains (By similarity)

View neXtProt modification sites for NX_Q99983

OMD Protein expression data from MOPED¹, PaxDb² and MAXQB³ : About this image

REFSEQ proteins: NP_005005.1

ENSEMBL proteins:

ENSP00000364700

Reactome Protein details: Q99983
Human Recombinant Protein Products for OMD:

	Browse Purified and Recombinant Proteins at EMD Millipore
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	Novus Biologicals OMD Proteins Novus Biologicals OMD Lysates
	Sino Biological Recombinant Protein for OMD Sino Biological Cell Lysate for OMD
	Browse ProSpec Recombinant Proteins
	Cloud-Clone Corp. Proteins for OMD

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	TAS	--
GO:0005578	proteinaceous extracellular matrix	IEA	--
GO:0005796	Golgi lumen	TAS	--
GO:0043202	lysosomal lumen	TAS	--

OMD for ontologies About GeneDecksing

OMD Antibody Products:

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	R&D Systems Antibodies for OMD (Osteoadherin/OSAD)
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	GenScript Custom Superior Antibodies Services for OMD
	Novus Biologicals OMD Antibodies
	Abcam antibodies for OMD
	Cloud-Clone Corp. Antibodies for OMD
	ThermoFisher Antibody for OMD
	LSBio Antibodies in human, mouse, rat for OMD

Assay Products for OMD:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Assay Services for OMD
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for OMD
	Browse Enzo Life Sciences for kits & assays
	Cloud-Clone Corp. ELISAs for OMD Cloud-Clone Corp. CLIAs for OMD

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

HGNC Gene Families:

SLRR: Proteoglycans / Extracellular Matrix : Small leucine-rich repeats

3 InterPro protein domains:

IPR001611 Leu-rich_rpt

IPR003591 Leu-rich_rpt_typical-subtyp

IPR000372 LRR-contain_N

Graphical View of Domain Structure for InterPro Entry Q99983

ProtoNet protein and cluster: Q99983

1 Blocks protein domain: IPB000372 Cysteine-rich flanking region

UniProtKB/Swiss-Prot: OMD_HUMAN, Q99983

Similarity: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily

Similarity: Contains 11 LRR (leucine-rich) repeats

Similarity: Contains 1 LRRNT domain

OMD for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: OMD_HUMAN, Q99983

Function: May be implicated in biomineralization processes. Has a function in binding of osteoblasts via the

alpha(V)beta(3)-integrin (By similarity)

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	--	--

OMD for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for OMD:

Decreased POU5F1-GFP protein e

1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Omd):

behavior/neurological

OMD for phenotypes About GeneDecksing

Animal Models:
MGI mouse knock-out Omd^tm1Lex for OMD

inGenious Targeting Laboratory - Custom generated mouse model solutions for OMD

inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for OMD

genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for OMD

genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for OMD

miRNA Products:		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat OMD
		6 QIAGEN miScript miRNA Assays for microRNAs that regulate OMD:
		hsa-miR-576-5p hsa-miR-875-5p hsa-miR-3662 hsa-miR-578 hsa-miR-551b* hsa-miR-3144-3p
		SwitchGear 3'UTR luciferase reporter plasmid: OMD 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene RNAi products in human, mouse, rat for OMD
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Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for OMD
			Sirion Biotech Customized adenovirus for overexpression of OMD

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene clones in human, mouse for OMD (see all 7) OriGene ORF clones in mouse, rat for OMD OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: OMD (NM_005014)
		Sino Biological Human cDNA Clone for OMD
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for OMD
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OMD
		Sirion Biotech Customized lentivirus for stable overexpression of OMD Customized lentivirus expression plasmids for stable overexpression of OMD

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for OMD
		LifeMap BioReagents: cell lines associated with OMD: PureStem MEL2, NCr-fac Progenitor, PureStem SM30, NCr-fac & Meso-latp Progenitor

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OMD

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

SuperPaths for OMD About

See pathways by source

SuperPath

Selected contained pathways About (see all per SuperPath)

MPS IIIC - Sanfilippo syndrome C

MPS IIIC - Sanfilippo syndrome C	0.48	Glycosaminoglycan metabolism	0.48
MPS IV - Morquio syndrome A	0.48	MPS IIID - Sanfilippo syndrome D	0.48
MPS VI - Maroteaux-Lamy syndrome	0.48	MPS I - Hurler syndrome	0.48
MPS IV - Morquio syndrome B	0.48	MPS IX - Natowicz syndrome	0.48

Keratan sulfate biosynthesis

	Keratan sulfate biosynthesis	0.82			Keratan sulfate degradation	0.38
	Keratan sulfate/keratin metabolism	0.82

Metabolism

Metabolism

0.40

Disease

Disease

Pathways by source See SuperPaths
Show all pathways

5/19 Reactome Pathways for OMD (see all 19)

	MPS VI - Maroteaux-Lamy syndrome
	Metabolism
	Disease
	Keratan sulfate/keratin metabolism
	MPS II - Hunter syndrome

OMD for pathways About GeneDecksing

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for OMD

STRING Interaction Network Preview (showing 5 interactants - click image to see 19)

5/19 Interacting proteins for OMD (ENSP00000364700⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 19)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
FMOD	ENSP00000347041⁴	STRING: ENSP00000347041
KERA	ENSP00000266719⁴	STRING: ENSP00000266719
LUM	ENSP00000266718⁴	STRING: ENSP00000266718
OGN	ENSP00000262551⁴	STRING: ENSP00000262551
PRELP	ENSP00000343924⁴	STRING: ENSP00000343924

About this table

Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005975	carbohydrate metabolic process	TAS	--
GO:0007155	cell adhesion	IEA	--
GO:0018146	keratan sulfate biosynthetic process	TAS	--
GO:0030203	glycosaminoglycan metabolic process	TAS	--
GO:0042339	keratan sulfate metabolic process	TAS	--

OMD for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

OMD for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for OMD

1 HMDB Compound for OMD About this table

Compound	Synonyms	CAS #	PubMed Ids
Keratan	Kerato sulfate (see all 4)	69992-87-6	--

2 Novoseek inferred chemical compound relationships for OMD gene About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
leucine	36.5	4	16970923 (1), 12704803 (1)
tyrosine	11.1	2	19700767 (1), 14551184 (1)

Search CenterWatch for drugs/clinical trials and news about OMD

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for OMD gene:

NM_005014.2

Unigene Cluster for OMD:

Osteomodulin

Hs.94070 [show with all ESTs]

Unigene Representative Sequence: NM_005014

1 Ensembl transcript including schematic representation, and UCSC links where relevant:

ENST00000375550(uc004asd.4)

miRNA Products:		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat OMD
		6 QIAGEN miScript miRNA Assays for microRNAs that regulate OMD:
		hsa-miR-576-5p hsa-miR-875-5p hsa-miR-3662 hsa-miR-578 hsa-miR-551b* hsa-miR-3144-3p
		SwitchGear 3'UTR luciferase reporter plasmid: OMD 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene RNAi products in human, mouse, rat for OMD
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OMD

Clone Products:		OriGene clones in human, mouse for OMD (see all 7) OriGene ORF clones in mouse, rat for OMD OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: OMD (NM_005014)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for OMD
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OMD
		Sirion Biotech Customized lentivirus for stable overexpression of OMD Customized lentivirus expression plasmids for stable overexpression of OMD

Primer Products:		OriGene qPCR primer pairs and template standards for OMD OriGene qSTAR qPCR primer pairs in human, mouse for OMD
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat OMD
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OMD
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OMD

Additional mRNA sequence:

AB000114.1 AK225922.1 AK313055.1 AY358872.1 BC046356.1

5 DOTS entries:

DT.121154232 DT.212266 DT.100812526 DT.100812527 DT.91720490

24/69 AceView cDNA sequences (see all 69):

BP343015 CA413997 AI638243 CA414013 AI148952 AY358872 AI655497 BC046356

N30894 BX097827 AI189981 AU117423 AI655516 AU119451 AI952953 BG900613

AA453328 AI989443 CA397539 BI522775 CA774638 AI138710 Z30156 AW978810

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

OMD expression in normal human tissues (normalized intensities) OMD embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: --

About this image

OMD expression in embryonic tissues and stem cells About this table

Data from LifeMap, the Embryonic Development and Stem Cells Database

5/10 selected tissues (see all 10) fully expand


Cartilage (Muscoskeletal System) fully expand to see all 15 entries
HyStem+TGFbeta3+GDF5-induced MEL2 cells
Normal Human Articular chondrocytes (NHAC)

Bone (Muscoskeletal System) fully expand to see all 15 entries
HyStem+TGFbeta3+GDF5-induced MEL2 cells

Neural Crest (Gastrulation Derivatives) fully expand to see all 3 entries
PureStem 4D20.8, NCr-fac Progenitor

Adipose (Muscoskeletal System) fully expand to see all 3 entries
HyStem+BMP4-induced E15 cells

Ovary (Reproductive System) fully expand to see all 2 entries
Pre-Granulosa Cells Primordial Follicle

See OMD Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for OMD

SOURCE GeneReport for Unigene cluster: Hs.94070

UniProtKB/Swiss-Prot: OMD_HUMAN, Q99983

Tissue specificity: Bone specific

SABiosciences Custom PCR Arrays for OMD

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		SABiosciences RT² qPCR Primer Assay in human, mouse, rat OMD
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OMD

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OMD

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for OMD gene from 4/9 species (see all 9) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Omd^{1 , 5}	osteomodulin^{1, 5}	85.65(n)¹ 80.14(a)¹		13 (25.33 cM)⁵ 27047¹ NM_012050.2¹ NP_036180.1¹ 49582766⁵
chicken (Gallus gallus)	Aves	OMD⁶	osteomodulin	58(a)	1 ↔ 1	12(3409133-3419427)
lizard (Anolis carolinensis)	Reptilia	OMD⁶	Uncharacterized protein	56(a)	1 ↔ 1	2(156204671-156222543)
zebrafish (Danio rerio)	Actinopterygii	omd¹	osteomodulin	57.12(n) 50.26(a)		557913 XM_681068.1 XP_686160.1

ENSEMBL Gene Tree for OMD (if available)
TreeFam Gene Tree for OMD (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for OMD gene

PODN² FLRT1² PODNL1² FMOD² KERA² PRELP² FLRT3² ASPN²

BGN² DCN² FLRT2² ECM2² LUM²

4 SIMAP similar genes for OMD using alignment to 1 protein entry: OMD_HUMAN:

KERA LUM PRELP FMOD

OMD for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Clinical significance	Chr 9 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data				Transcription Related Data				Allele Frequencies
			--	--	--		--	--
VAR_052015⁴	--	--	see VAR_052015	2	E G	mis⁴		0	--	--	--	--
VAR_052017⁴	--	--	see VAR_052017	2	I T	mis⁴		0	--	--	--	--
VAR_052014⁴	--	--	see VAR_052014	2	D G	mis⁴		0	--	--	--	--
VAR_052016⁴	--	--	see VAR_052016	2	S N	mis⁴		0	--	--	--	--
VAR_052018⁴	--	--	see VAR_052018	2	C W	mis⁴		0	--	--	--	--

HapMap Linkage Disequilibrium report for OMD (95176527 - 95186836 bp)

Structural Variations
Database of Genomic Variants (DGV) 1 variation for OMD: About this table

Variant ID	Type	Subtype	PubMed ID
nsv893573	CNV	Gain	21882294

SABiosciences Cancer Mutation PCR Assays

SeqTarget long-range PCR primers for resequencing OMD

DNA2.0 Custom Variant and Variant Library Synthesis for OMD

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

8 diseases for OMD: About MalaCards

occult macular dystrophy meckel's diverticulum hallermann-streiff syndrome aneurysmal bone cysts

blepharospasm morquio syndrome b dental caries parkinson's disease

2 diseases from the University of Copenhagen DISEASES database for OMD:

Blepharospasm Parkinson's disease

OMD for disorders About GeneDecksing

Congresses - knowledge worth sharing:
Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

Export disorders for OMD gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for OMD gene, integrated from 9 sources (see all 29):
(articles sorted by number of sources associating them with OMD)

Utopia: connect your pdf to the dynamic
world of online information

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)^{1, 2} Clark H.F.... Gray A.M. (2003)
Expression of the small leucine-rich proteoglycan osteoadherin/osteomodulin in human dental pulp and developing rat teeth. (PubMed id 10913920)^{1, 9} Buchaille R....Bleicher F. (2000)
TGF beta 1 signaling and stimulation of osteoadherin in human odontoblasts in vitro. (PubMed id 12489179)^{1, 9} Lucchini M....Farges J.C. (2002)
The tyrosine sulfate-rich domains of the LRR proteins fibromodulin and osteoadherin bind motifs of basic clusters in a variety of he parin-binding proteins, including bioactive factors. (PubMed id 19700767)^{1, 9} Tillgren V....HeinegAYrd D. (2009)
Identification of tyrosine sulfation in extracellular leucine-rich repeat proteins using mass spectrometry. (PubMed id 14551184)^{2, 9} Onnerfjord P....Heinegard D. (2004)
Immunodetection of osteoadherin in murine tooth extracellular matrices. (PubMed id 14673660)¹ Couble M.L....Staquet M.J. (2004)
DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)² Humphray S.J.... Dunham I. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )² Aoki H.... Hino O. (2000)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 4958	HGNC: 8134	AceView: OMD	Ensembl:ENSG00000127083	euGenes: HUgn4958
ECgene: OMD	H-InvDB: OMD

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for OMD	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for OMD	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for OMD gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for OMD gene:
Search GeneIP for patents involving OMD

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
About This Section


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