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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

OMD Gene

protein-coding   GIFtS: 55
GCID: GC09M095176

osteomodulin
 Explore 8 diseases affiliated with
OMD via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for OMD    

Aliases
for OMD gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Osteomodulin1     KSPG Osteomodulin2 3
SLRR2C1 2 3     Osteoadherin3
Keratan Sulfate Proteoglycan Osteomodulin2 3     Osteoadherin Proteoglycan2
OSAD2 3     Osteoadherin3

External Ids:    HGNC: 81341   Entrez Gene: 49582   Ensembl: ENSG000001270837   UniProtKB: Q999833   

Export aliases for OMD gene to outside databases

Previous GC identifers: GC09M086003 GC09M086904 GC09M088475 GC09M090517 GC09M092256 GC09M094216 GC09M064853


Summaries
for OMD gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: OMD_HUMAN, Q99983
Function: May be implicated in biomineralization processes. Has a function in binding of osteoblasts via the
alpha(V)beta(3)-integrin (By similarity)

Gene Wiki entry for OMD


Genomic Views
for OMD gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000009.11  NC_018920.1  NT_008470.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the OMD gene promoter:
         AP-1   ATF-2   FOXO3   FOXO3b   SRY   POU2F1   POU2F1a   FOXO3a   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: OMD promoter sequence
   Search SABiosciences Chromatin IP Primers for OMD

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OMD


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q22.31   Ensembl cytogenetic band:  9q22.31   HGNC cytogenetic band: 9q22.31

OMD Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
OMD gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M095176:  view genomic region     (about GC identifiers)

Start:
 95,176,527 bp from pter      End:
 95,186,836 bp from pter
Size:
 10,310 bases      Orientation:
 minus strand

Proteins
for OMD gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: OMD_HUMAN, Q99983 (See protein sequence)
Recommended Name: Osteomodulin precursor  
Size: 421 amino acids; 49492 Da
Subunit: Binds the alpha(V)beta(3)-integrin (By similarity)
Subcellular location: Secreted, extracellular space, extracellular matrix (By similarity)
Secondary accessions: Q5TBF4

Explore the universe of human proteins at neXtProt for OMD: NX_Q99983

Post-translational modifications:

  • Binds keratan sulfate chains (By similarity)1
  • View neXtProt modification sites for NX_Q99983

    • OMD Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_005005.1  
    ENSEMBL proteins: 
     ENSP00000364700  
    Reactome Protein details: Q99983
    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    R&D Systems Recombinant & Natural Proteins for OMD (Osteoadherin/OSAD)
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate: OMD
    OriGene Custom Protein Services for OMD 
    GenScript Custom Purified and Recombinant Proteins Services for OMD
    Novus Biologicals OMD Proteins
    Novus Biologicals OMD Lysates
    Sino Biological Recombinant Protein for OMD
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for OMD

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region TAS--
    GO:0005578proteinaceous extracellular matrix IEA--
    GO:0005796Golgi lumen TAS--
    GO:0043202lysosomal lumen TAS--


    OMD for ontologies           About GeneDecksing



    OMD Antibody Products: 
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    Uscn Antibodies for OMD
    ThermoFisher Antibodies for OMD

    Assay Products for OMD: 
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    Uscn ELISAs and CLIAs for OMD

    Protein Domains /
    Families
    for OMD gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    OMD for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR001611 Leu-rich_rpt
     IPR003591 Leu-rich_rpt_typical-subtyp
     IPR000372 LRR-contain_N

    Graphical View of Domain Structure for InterPro Entry Q99983

    ProtoNet protein and cluster: Q99983

    1 Blocks protein family: IPB000372 Cysteine-rich flanking region

    UniProtKB/Swiss-Prot: OMD_HUMAN, Q99983
    Similarity: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily
    Similarity: Contains 11 LRR (leucine-rich) repeats
    Similarity: Contains 1 LRRNT domain


    Function
    for OMD gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: OMD_HUMAN, Q99983
    Function: May be implicated in biomineralization processes. Has a function in binding of osteoblasts via the
    alpha(V)beta(3)-integrin (By similarity)

    miRNA
    Products:            		 OriGene 3'-UTR Clone: OMD
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat OMD
    6 QIAGEN miScript miRNA Assays for microRNAs that regulate OMD:
    hsa-miR-576-5p hsa-miR-875-5p hsa-miR-3662 hsa-miR-578 hsa-miR-551b* hsa-miR-3144-3p
    SwitchGear 3'UTR luciferase reporter plasmid: OMD 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for OMD (see all 7)
    OriGene shRNA RFP: OMD
    OriGene siRNA: OMD
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OMD

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for OMD

    Clone
    Products:             		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for OMD (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for OMD
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: OMD (NM_005014)
    Sino Biological Human cDNA Clone for OMD
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for OMD
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OMD 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for OMD
    LifeMap BioReagents: cell lines associated with OMD: PureStem MEL2, NCr-fac Progenitor,
    PureStem SM30, NCr-fac & Meso-latp Progenitor

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OMD

    1 GenomeRNAi human phenotype for OMD:
     Decreased POU5F1-GFP protein e 

    Animal Models:
         Mouse knock-out Omdtm1Lex for OMD
         1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Omd):
     behavior/neurological 

    OMD for phenotypes           About GeneDecksing


    Pathways & Interactions
    for OMD gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1MPS IIIC - Sanfilippo syndrome C
    8/14 pathways (see all 14)
    		MPS IIIC - Sanfilippo syndrome C1.00
    		MPS IIIA - Sanfilippo syndrome A1.00
    		MPS I - Hurler syndrome1.00
    		MPS IIID - Sanfilippo syndrome D1.00
    		Mucopolysaccharidoses1.00
    		MPS IX - Natowicz syndrome1.00
    		MPS IV - Morquio syndrome A1.00
    		MPS II - Hunter syndrome1.00
    2Extracellular KSPG translocates to the lysosome for degradation
    		Extracellular KSPG translocates to the lysosome for degradation1.00
    		Keratan sulfate is cleaved from its proteoglycan by an unknown galactosidase1.00
    		KSPG is secreted from the cell1.00
    		Keratan sulfate degradation0.58
    3Keratan sulfate biosynthesis
    		Keratan sulfate biosynthesis1.00
    		Keratan sulfate/keratin metabolism0.84
    4Disease
    		Disease1.00
    5Metabolism
    		Metabolism1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    5/22        Reactome Pathways for OMD (see all 22)
        MPS VI - Maroteaux-Lamy syndrome
    Metabolism
    Disease
    Keratan sulfate/keratin metabolism
    MPS IIIA - Sanfilippo syndrome A



    OMD for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for OMD

    STRING Interaction Network Preview (showing 5 interactants - click image to see 19)

    5/19 Interacting proteins for OMD (ENSP000003647004) via UniProtKB, MINT, STRING, and/or I2D (see all 19)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    FMODENSP000003470414STRING: ENSP00000347041
    KERAENSP000002667194STRING: ENSP00000266719
    LUMENSP000002667184STRING: ENSP00000266718
    OGNENSP000002625514STRING: ENSP00000262551
    PRELPENSP000003439244STRING: ENSP00000343924
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005975carbohydrate metabolic process TAS--
    GO:0007155cell adhesion IEA--
    GO:0018146keratan sulfate biosynthetic process TAS--
    GO:0030203glycosaminoglycan metabolic process TAS--
    GO:0042339keratan sulfate metabolic process TAS--


    OMD for ontologies           About GeneDecksing



    Drugs & Compounds
    for OMD gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    OMD for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for OMD

    1 HMDB Compound for OMD    About this table
    CompoundSynonyms CAS #PubMed Ids
    KeratanKerato sulfate (see all 4)69992-87-6--
    2 Novoseek chemical compound relationships for OMD gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    leucine 36.5 4 16970923 (1), 12704803 (1)
    tyrosine 11.1 2 19700767 (1), 14551184 (1)

    Search CenterWatch for drugs/clinical trials and news about OMD 

    Transcripts
    for OMD gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for OMD gene: 
    NM_005014.2  

    Unigene Cluster for OMD:

    Osteomodulin
    Hs.94070  [show with all ESTs]
    Unigene Representative Sequence: NM_005014
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000375550(uc004asd.4)

    miRNA
    Products:             		 OriGene 3'-UTR Clone: OMD
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat OMD
    6 QIAGEN miScript miRNA Assays for microRNAs that regulate OMD:
    hsa-miR-576-5p hsa-miR-875-5p hsa-miR-3662 hsa-miR-578 hsa-miR-551b* hsa-miR-3144-3p
    SwitchGear 3'UTR luciferase reporter plasmid: OMD 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for OMD (see all 7)
    OriGene shRNA RFP: OMD
    OriGene siRNA: OMD
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OMD
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for OMD (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for OMD
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: OMD (NM_005014)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for OMD
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OMD 
    Primer
    Products:            		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for OMD
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat OMD
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OMD
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OMD

    Additional cDNA sequence: 

    AB000114.1 AK225922.1 AK313055.1 AY358872.1 BC046356.1 

    5 DOTS entries:

    DT.121154232  DT.212266  DT.100812526  DT.100812527  DT.91720490 

    24/69 AceView cDNA sequences (see all 69):

    BX097827 AI655516 AU119451 AI189981 BC046356 CA413997 AI148952 BP343015 
    AI638243 CA414013 AU117423 AI655497 AY358872 N30894 BI823766 W96214 
    AL702582 NM_005014 BQ881634 AW978810 CA397539 AI138710 N27077 W96308 

    GeneLoc Exon Structure


    Expression
    for OMD gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    OMD expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    OMD expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    2 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    OvaryPrimary FollicleGranulosa CellsOvary
    OvaryPrimordial FolliclePre-Granulosa CellsOvary
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 10/16 LifeMap Cells (see all 16) 
    NameCategory
    PureStem™ mesenchymal progenitor SM30 (Embryonic Progenitor Cell)Adipose, Bone, Cartilage
    PureStem™ mesenchymal progenitor MEL2 (Embryonic Progenitor Cell)Adipose, Bone, Cartilage
    PureStem™ mesenchymal progenitor 4D20.8 (Embryonic Progenitor Cell)Lateral Plate Mesoderm, Neural Crest
    Micromass-induced chondrocytes (Micromass chondrogen...)Bone, Cartilage
    HyStem+TGF?3+GDF5-induced SM30 cells (HyStem+TGF?3+GDF5 in...)Bone, Cartilage
    HyStem+BMP4-induced SM30 cells (HyStem+BMP4 inductio...)Adipose, Bone, Cartilage
    HyStem+TGF?3+GDF5-induced MEL2 cells (HyStem+TGF?3+GDF5 in...)Bone, Cartilage
    HyStem+BMP4-induced 7SMOO32 cells (HyStem+BMP4 inductio...)Adipose
    HyStem+TGF?3+GDF5-induced 7SMOO32 cells (HyStem+TGF?3+GDF5 in...)Bone, Cartilage
    TGF?3+BMP7-induced chondrocytes (Chondrogenic HyStem+...)Bone, Cartilage

    See OMD Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for OMD

    SOURCE GeneReport for Unigene cluster: Hs.94070

    UniProtKB/Swiss-Prot: OMD_HUMAN, Q99983
    Tissue specificity: Bone specific

        SABiosciences Custom PCR Arrays for OMD
    Primer
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OMD
    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OMD

    Orthologs
    for OMD gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for OMD gene from 3/10 species (see all 10)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves PODN6
    		 Uncharacterized protein
    		 22(a)
    		 possible ortholog
    		 8(25317987-25325492)
    lizard
    (Anolis carolinensis)    		 Reptilia OMD6
    		 --
    		 57(a)
    		 1 ↔ 1
    		 2(156219033-156221145)
    zebrafish
    (Danio rerio)    		 Actinopterygii omd1 osteomodulin 57.12(n)
    50.26(a)    		   557913  XM_681068.1  XP_686160.1 


    ENSEMBL Gene Tree for OMD (if available)
    TreeFam Gene Tree for OMD (if available) 

    Paralogs
    for OMD gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for OMD gene
    OGN2  OPTC2  PODN2  PODNL12  FMOD2  PRELP2  KERA2  ASPN2  
    BGN2  DCN2  EPYC2  ECM22  LUM2  
    4 SIMAP similar genes for OMD using alignment to 1 protein entry:     OMD_HUMAN:
    KERA    LUM    PRELP    FMOD

    OMD for paralogs           About GeneDecksing



    Genomic Variants
    for OMD gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/199 NCBI SNPs in OMD are shown (see all 199)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 9 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1889364031,2
    		--95176041(+) TAGACA/GAATGA 2 -- int1 ds50010--------
    rs727524631,2
    		C,F,--95176103(+) AGGTGG/AGCGTT 2 -- int1 ds50012Minor allele frequency- A:0.03NA EA 240
    rs1925353711,2
    		--95176511(+) TATTGA/GCTGAT 2 -- int1 ds50010--------
    rs1827228591,2
    		--95176563(+) CCAACA/TCTAAT 2 -- ut31 int10--------
    rs412786831,2
    		C,--95176704(+) TGCTGG/AAATCT 2 -- int1 ut311Minor allele frequency- A:0.50NA 2
    rs18029731,2
    		--95176831(-) CCAAGA/GCATAC 2 -- int1 ut310--------
    rs412786851,2
    		--95176841(+) GGTCCG/TTAGTA 2 -- ut31 int10--------
    rs1426041011,2
    		--95176882(+) CATTCG/TATGTG 2 -- ut31 int10--------
    rs1874527531,2
    		--95176976(+) AGAAAA/GTGGTC 2 -- int1 ut310--------
    rs109923271,2
    		C--95177044(+) CCTCAA/GAGTGA 2 -- int1 ut31 ese30--------

    HapMap Linkage Disequilibrium report for OMD (95176527 - 95186836 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for OMD: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing OMD
    DNA2.0 Custom Variant and Variant Library Synthesis for OMD

    Disorders / Diseases
    for OMD gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMD for disorders           About GeneDecksing

    8 diseases for OMD:    About MalaCards
    hallermann-streiff syndrome    occult macular dystrophy    meckel's diverticulum    aneurysmal bone cysts
    dental caries    macular dystrophy    blepharospasm    parkinson's disease

    2 diseases from the University of Copenhagen DISEASES database for OMD:
    Blepharospasm     Parkinson's disease

    Export disorders for OMD gene to outside databases

    Publications
    for OMD gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for OMD gene, integrated from 9 sources (see all 29):
    (articles sorted by number of sources associating them with OMD)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    3. Expression of the small leucine-rich proteoglycan osteoadherin/osteomodulin in human dental pulp and developing rat teeth. (PubMed id 10913920)1, 9 Buchaille R....Bleicher F. (2000)
    4. TGF beta 1 signaling and stimulation of osteoadherin in human odontoblasts in vitro. (PubMed id 12489179)1, 9 Lucchini M....Farges J.C. (2002)
    5. The tyrosine sulfate-rich domains of the LRR proteins fibromodulin and osteoadherin bind motifs of basic clusters in a variety of he parin-binding proteins, including bioactive factors. (PubMed id 19700767)1, 9 Tillgren V....HeinegAYrd D. (2009)
    6. Identification of tyrosine sulfation in extracellular leucine-rich repeat proteins using mass spectrometry. (PubMed id 14551184)2, 9 Onnerfjord P....Heinegard D. (2004)
    7. Immunodetection of osteoadherin in murine tooth extracellular matrices. (PubMed id 14673660)1 Couble M.L....Staquet M.J. (2004)
    8. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)2 Humphray S.J.... Dunham I. (2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)

    External Searches for OMD gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    Genome Databases showing OMD gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 4958 HGNC: 8134 AceView: OMD Ensembl:ENSG00000127083 euGenes: HUgn4958
    ECgene: OMD H-InvDB: OMD

    Other Databases showing OMD gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing OMD gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for OMD Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for OMD Genetics and Cytogenetics in Oncology and Haematology

    Intellectual Property
    for OMD gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for OMD gene:
    Search GeneIP for patents involving OMD

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
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     OMD Proteins, Antibodies, CLIAs, and ELISAs
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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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