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OMD Gene

protein-coding   GIFtS: 56
GCID: GC09M095176

Osteomodulin

  See OMD-related diseases
at
MalaCards
 

Aliases
for OMD gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
osteomodulin1 2     SLRR2C2 3
Osteoadherin Proteoglycan1 2     KSPG Osteomodulin2 3
Keratan Sulfate Proteoglycan Osteomodulin2 3     Osteoadherin3
OSAD2 3     

External Ids:    HGNC: 81341   Entrez Gene: 49582   Ensembl: ENSG000001270837   UniProtKB: Q999833   

Export aliases for OMD gene to outside databases

Previous GC identifers: GC09M086003 GC09M086904 GC09M088475 GC09M090517 GC09M092256 GC09M094216 GC09M064853


Summaries
for OMD gene

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for OMD Gene:
OMD (osteomodulin) is a protein-coding gene. Diseases associated with OMD include aneurysmal bone cysts, and blepharospasm. An important paralog of this gene is PODN.

UniProtKB/Swiss-Prot: OMD_HUMAN, Q99983
Function: May be implicated in biomineralization processes. Has a function in binding of osteoblasts via the
alpha(V)beta(3)-integrin (By similarity)

Gene Wiki entry for OMD Gene


Genomic Views
for OMD gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000009.11  NC_018920.2  NT_008470.20  
Regulatory elements:
   Regulatory transcription factor binding sites in the OMD gene promoter:
         AP-1   ATF-2   FOXO3   FOXO3b   SRY   POU2F1   POU2F1a   FOXO3a   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: OMD promoter sequence
   Search Chromatin IP Primers for OMD

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat OMD


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q22.31   Ensembl cytogenetic band:  9q22.31   HGNC cytogenetic band: 9q22.31

OMD Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
OMD gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M095176:  view genomic region     (about GC identifiers)

Start:
 95,176,527 bp from pter      End:
 95,186,836 bp from pter
Size:
 10,310 bases      Orientation:
 minus strand

Proteins
for OMD gene

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: OMD_HUMAN, Q99983 (See protein sequence)
Recommended Name: Osteomodulin precursor  
Size: 421 amino acids; 49492 Da
Subunit: Binds the alpha(V)beta(3)-integrin (By similarity)
Secondary accessions: Q5TBF4

Explore the universe of human proteins at neXtProt for OMD: NX_Q99983

Explore proteomics data for OMD at MOPED

Post-translational modifications: 

  • Binds keratan sulfate chains (By similarity)1
  • Glycosylation2 at Asn113, Asn121, Asn187, Asn242, Asn316

    • See OMD Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_005005.1  
    ENSEMBL proteins: 
     ENSP00000364700  
    Reactome Protein details: Q99983

    OMD Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
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    OriGene Protein Over-expression Lysate for OMD
    OriGene Custom MassSpec
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    GenScript Custom Purified and Recombinant Proteins Services for OMD
    Novus Biologicals OMD Proteins
    Novus Biologicals OMD Lysates
    Sino Biological Recombinant Protein for OMD
    Sino Biological Cell Lysate for OMD
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for OMD

         		 Search eBioscience for Proteins for OMD 

         		antibodies-online proteins for OMD (6 products) 

         		antibodies-online peptides for OMD

    OMD Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Abcam antibodies for OMD
    Cloud-Clone Corp. Antibodies for OMD
    ThermoFisher Antibody for OMD
    antibodies-online antibodies for OMD (31 products) 

    OMD Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for OMD
    Cloud-Clone Corp. CLIAs for OMD
    Search eBioscience for ELISAs for OMD 
    antibodies-online kits for OMD (8 products) 

    Domains /
    Families
    for OMD gene

    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

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    SLRR: Proteoglycans / Extracellular Matrix : Small leucine-rich repeats

    3 InterPro protein domains:
     IPR001611 Leu-rich_rpt
     IPR003591 Leu-rich_rpt_typical-subtyp
     IPR000372 LRR-contain_N

    Graphical View of Domain Structure for InterPro Entry Q99983

    ProtoNet protein and cluster: Q99983

    1 Blocks protein domain: IPB000372 Cysteine-rich flanking region

    UniProtKB/Swiss-Prot: OMD_HUMAN, Q99983
    Similarity: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily
    Similarity: Contains 11 LRR (leucine-rich) repeats
    Similarity: Contains 1 LRRNT domain


    Find genes that share domains with OMD           About GenesLikeMe


    Function
    for OMD gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: OMD_HUMAN, Q99983
    Function: May be implicated in biomineralization processes. Has a function in binding of osteoblasts via the
    alpha(V)beta(3)-integrin (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with OMD           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for OMD:
     Decreased POU5F1-GFP protein e 

         1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Omd):
     behavior/neurological 

    Find genes that share phenotypes with OMD           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Omdtm1Lex for OMD

       genOway: Develop your customized and physiologically relevant rodent model for OMD

    miRNA
    Products:            		Block miRNA regulation of human, mouse, rat OMD using miScript Target Protectors
    6 qRT-PCR Assays for microRNAs that regulate OMD:
    hsa-miR-576-5p hsa-miR-875-5p hsa-miR-3662 hsa-miR-578 hsa-miR-551b* hsa-miR-3144-3p
    SwitchGear 3'UTR luciferase reporter plasmid: OMD 3' UTR sequence
    Inhib. RNA
    Products:            		OriGene RNAi products in human, mouse, rat for OMD
    Predesigned siRNA for gene silencing in human, mouse, rat OMD

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for OMD

    Clone
    Products:             		 OriGene clones in human, mouse for OMD (see all 7)
    OriGene ORF clones in mouse, rat for OMD
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: OMD (NM_005014)
    Sino Biological Human cDNA Clone for OMD
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for OMD
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OMD

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for OMD
    ESI BIO PureStem Progenitors for OMD: 
    PureStem MEL2, NCr-fac Progenitor, PureStem SM30, NCr-fac & Meso-latp Progenitor
    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OMD


    Localization
    for OMD gene

    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    OMD_HUMAN, Q99983: Secreted, extracellular space, extracellular matrix (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular4
    golgi apparatus4
    lysosome4
    vacuole4
    plasma membrane2
    endoplasmic reticulum1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region TAS--
    GO:0005578proteinaceous extracellular matrix IEA--
    GO:0005796Golgi lumen TAS--
    GO:0043202lysosomal lumen TAS--

    Find genes that share ontologies with OMD           About GenesLikeMe


    Pathways & Interactions
    for OMD gene

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for OMD About    
    See pathways by source

    		      Powered
    by    		     
    SuperPathSelected contained pathways About (see all per SuperPath)
    1MPS VI - Maroteaux-Lamy syndrome
    		MPS VI - Maroteaux-Lamy syndrome0.45
    		MPS IV - Morquio syndrome B0.45
    		MPS IIIC - Sanfilippo syndrome C0.45
    		MPS IX - Natowicz syndrome0.45
    		MPS IIID - Sanfilippo syndrome D0.45
    		MPS IV - Morquio syndrome A0.45
    		MPS IIIA - Sanfilippo syndrome A0.45
    		Mucopolysaccharidoses0.45
    2Keratan sulfate/keratin metabolism
    		Keratan sulfate/keratin metabolism0.85
    		Keratan sulfate degradation0.00
    		Keratan sulfate biosynthesis0.85
    3Metabolism
    		Metabolism0.38
    4Disease
    		Disease


    Find genes that share SuperPaths with OMD           About GenesLikeMe

    Pathways by source                                   See SuperPaths
    Show all pathways



    2 Reactome Pathways for OMD
        Keratan sulfate biosynthesis
    Keratan sulfate degradation


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for OMD
    Interactions:

        GeneGlobe Interaction Network for OMD

    STRING Interaction Network Preview (showing 5 interactants - click image to see 21)

    Selected Interacting proteins for OMD (ENSP000003647004) via UniProtKB, MINT, STRING, and/or I2D (see all 21)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    FMODENSP000003470414STRING: ENSP00000347041
    KERAENSP000002667194STRING: ENSP00000266719
    LUMENSP000002667184STRING: ENSP00000266718
    OGNENSP000002625514STRING: ENSP00000262551
    PRELPENSP000003439244STRING: ENSP00000343924
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005975carbohydrate metabolic process TAS--
    GO:0007155cell adhesion IEA--
    GO:0018146keratan sulfate biosynthetic process TAS--
    GO:0030203glycosaminoglycan metabolic process TAS--
    GO:0042339keratan sulfate metabolic process TAS--

    Find genes that share ontologies with OMD           About GenesLikeMe



    Drugs & Compounds
    for OMD gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for OMD

    1 HMDB Compound for OMD    About this table
    CompoundSynonyms CAS #PubMed Ids
    KeratanKerato sulfate (see all 4)69992-87-6--

    2 Novoseek inferred chemical compound relationships for OMD gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    leucine 36.5 4 16970923 (1), 12704803 (1)
    tyrosine 11.1 2 19700767 (1), 14551184 (1)



    Find genes that share compounds with OMD           About GenesLikeMe



    Transcripts
    for OMD gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for OMD gene: 
    NM_005014.2  

    Unigene Cluster for OMD:

    Osteomodulin
    Hs.94070  [show with all ESTs]
    Unigene Representative Sequence: NM_005014
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000375550(uc004asd.4)
    miRNA
    Products:             		 Block miRNA regulation of human, mouse, rat OMD using miScript Target Protectors
    6 qRT-PCR Assays for microRNAs that regulate OMD:
    hsa-miR-576-5p hsa-miR-875-5p hsa-miR-3662 hsa-miR-578 hsa-miR-551b* hsa-miR-3144-3p
    SwitchGear 3'UTR luciferase reporter plasmid: OMD 3' UTR sequence
    Inhib. RNA
    Products:             		OriGene RNAi products in human, mouse, rat for OMD
    Predesigned siRNA for gene silencing in human, mouse, rat OMD
    Clone
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    OriGene ORF clones in mouse, rat for OMD
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: OMD (NM_005014)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for OMD
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OMD
    Primer
    Products:            		OriGene qPCR primer pairs and template standards for OMD
    OriGene qSTAR qPCR primer pairs in human, mouse for OMD
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat OMD
      QuantiTect SYBR Green Assays in human, mouse, rat OMD
      QuantiFast Probe-based Assays in human, mouse, rat OMD

    Additional mRNA sequence: 

    AB000114.1 AK225922.1 AK313055.1 AY358872.1 BC046356.1 

    5 DOTS entries:

    DT.121154232  DT.212266  DT.100812526  DT.100812527  DT.91720490 

    Selected AceView cDNA sequences (see all 69):

    AI189981 CA414013 AI655497 BX097827 CA413997 AI148952 BP343015 AY358872 
    BC046356 AI638243 N30894 AU117423 AI655516 AU119451 BI522775 BI491660 
    N27077 CA412649 AW978810 BG900613 AI989443 AI952953 BQ881634 Z30156 

    GeneLoc Exon Structure


    Expression
    for OMD gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    OMD expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    OMD Expression
    About this image


    OMD expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 7) fully expand
     
     Bone (Muscoskeletal System)    fully expand to see all 16 entries
             Micromass-induced chondrocytes
     
     Cartilage (Muscoskeletal System)    fully expand to see all 14 entries
             Micromass-induced chondrocytes
     
     Neural Crest (Gastrulation Derivatives)    fully expand to see all 3 entries
             PureStem 4D20.8, NCr-fac Progenitor
     
     Adipose (Muscoskeletal System)    fully expand to see all 3 entries
             HyStem+BMP4-induced E15 cells
     
     Ovary (Reproductive System)    fully expand to see all 2 entries
             Pre-Granulosa Cells Primordial Follicle
    OMD Protein expression data from MOPED1, PaxDb2 and MaxQB3:     About this image

    OMD Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.94070

    UniProtKB/Swiss-Prot: OMD_HUMAN, Q99983
    Tissue specificity: Bone specific

        Custom PCR Arrays for OMD
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OMD

    Orthologs
    for OMD gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for OMD gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Omd1 , 5 osteomodulin1, 5 85.39(n)1
    79.9(a)1    		   13 (25.33 cM)5
    270471  NM_012050.21  NP_036180.11 
     495827665 
    chicken
    (Gallus gallus)    		 Aves OMD1 osteomodulin 68.4(n)
    61.54(a)    		   101747586  XM_004944504.1  XP_004944561.1 
    lizard
    (Anolis carolinensis)    		 Reptilia OMD6
    		 osteomodulin
    		 56(a)
    		 1 ↔ 1
    		 2(156204671-156222543)
    zebrafish
    (Danio rerio)    		 Actinopterygii omd1 osteomodulin 57.82(n)
    51.69(a)    		   557913  XM_681068.2  XP_686160.1 


    ENSEMBL Gene Tree for OMD (if available)
    TreeFam Gene Tree for OMD (if available)

    Paralogs
    for OMD gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for OMD gene
    PODN2  FLRT12  PODNL12  FMOD2  KERA2  PRELP2  FLRT32  ASPN2  
    BGN2  DCN2  FLRT22  ECM22  LOC1005090912  LUM2  
    4 SIMAP similar genes for OMD using alignment to 1 protein entry:     OMD_HUMAN:
    KERA    LUM    PRELP    FMOD

    Find genes that share paralogs with OMD           About GenesLikeMe



    Genomic Variants
    for OMD gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    5 SNPs for OMD    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 9 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs344132591,2,4
    		----see VAR_0520152 mis40--------
    rs357799011,2,4
    		----see VAR_0520172 mis40--------
    rs340698711,2,4
    		----see VAR_0520142 mis40--------
    rs348606581,2,4
    		----see VAR_0520162 mis40--------
    rs340591141,2,4
    		----see VAR_0520182 mis40--------

    HapMap Linkage Disequilibrium report for OMD (95176527 - 95186836 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for OMD:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv893573CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing OMD
    DNA2.0 Custom Variant and Variant Library Synthesis for OMD

    Disorders / Diseases
    for OMD gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus    		 2 diseases for OMD:    
    About MalaCards
    aneurysmal bone cysts    blepharospasm

    2 inferred disease relationships from the University of Copenhagen DISEASES database for OMD:
    Blepharospasm     Parkinson's disease

    Find genes that share disorders with OMD           About GenesLikeMe


    Export disorders for OMD gene to outside databases

    Publications
    for OMD gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

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    PubMed articles for OMD gene, integrated from 10 sources (see all 29):
    (articles sorted by number of sources associating them with OMD)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    3. Expression of the small leucine-rich proteoglycan osteoadherin/osteomodulin in human dental pulp and developing rat teeth. (PubMed id 10913920)1, 9 Buchaille R....Bleicher F. (Bone 2000)
    4. TGF beta 1 signaling and stimulation of osteoadherin in human odontoblasts in vitro. (PubMed id 12489179)1, 9 Lucchini M....Farges J.C. (Connect. Tissue Res. 2002)
    5. The tyrosine sulfate-rich domains of the LRR proteins fibromodulin and osteoadherin bind motifs of basic clusters in a variety of heparin-binding proteins, including bioactive factors. (PubMed id 19700767)1, 9 Tillgren V....HeinegAYrd D. (J. Biol. Chem. 2009)
    6. Identification of tyrosine sulfation in extracellular leucine-rich repeat proteins using mass spectrometry. (PubMed id 14551184)2, 9 Onnerfjord P.... Heinegaard D. (J. Biol. Chem. 2004)
    7. Immunodetection of osteoadherin in murine tooth extracellular matrices. (PubMed id 14673660)1 Couble M.L....Staquet M.J. (Histochem. Cell Biol. 2004)
    8. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)2 Humphray S.J.... Dunham I. (Nature 2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    10. Bone matrix proteins: isolation and characterization of a novel cell-binding keratan sulfate proteoglycan (osteoadherin) from bovine bone. (PubMed id 9566981)1 Wendel M....HeinegAYrd D. (J. Cell Biol. 1998)

    External Searches for OMD gene

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    Genome Databases showing OMD gene

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    Entrez Gene: 4958 HGNC: 8134 AceView: OMD Ensembl:ENSG00000127083 euGenes: HUgn4958
    ECgene: OMD H-InvDB: OMD

    Other Databases showing OMD gene

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    Specialized Databases showing OMD gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    PharmGKB entry for OMD Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for OMD Genetics and Cytogenetics in Oncology and Haematology

    Intellectual Property
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