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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

OLIG3 Gene

protein-coding GIFtS: 52
GCID: GC06M137855

oligodendrocyte transcription factor 3

Explore 4 diseases affiliated with
OLIG3 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Oligodendrocyte Transcription Factor 3¹ ²		BHLHB7³ ⁵
BHLHe20¹		Oligo3³
Bhlhb7¹ ²		BHLHE20³
Class B Basic Helix-Loop-Helix Protein 7² ³		Oligo3³
Class E Basic Helix-Loop-Helix Protein 20² ³		BHLHb7¹

External Ids:	HGNC: 18003¹	Entrez Gene: 167826²	Ensembl: ENSG00000177468⁷	OMIM: 609323⁵	UniProtKB: Q7RTU3³

Export aliases for OLIG3 gene to outside databases

Previous GC identifers: GC06M137660 GC06M137793 GC06M135375

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: OLIG3_HUMAN, Q7RTU3

Function: May determine the distinct specification program of class A neurons in the dorsal part of the spinal cord and

suppress specification of class B neurons

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000006.11 NC_018917.1 NT_025741.15

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the OLIG3 gene promoter:
SRF Nkx3-1 Nkx3-1 v4 SRF (504 AA) CUTL1 Nkx3-1 v1 HNF-1A Nkx3-1 v2 HNF-1 Nkx3-1 v3
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: OLIG3 promoter sequence

Search SABiosciences Chromatin IP Primers for OLIG3

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OLIG3

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q23.3 Ensembl cytogenetic band: 6q23.3 HGNC cytogenetic band: 6q23.3

OLIG3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
OLIG3 gene location

GeneLoc information about chromosome 6 GeneLoc Exon Structure

GeneLoc location for GC06M137855: view genomic region (about GC identifiers)

Start:	137,813,336 bp from pter	End:	137,815,531 bp from pter
Size:	2,196 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: OLIG3_HUMAN, Q7RTU3 (See protein sequence)

Recommended Name: Oligodendrocyte transcription factor 3

Size: 272 amino acids; 29358 Da

Subcellular location: Nucleus (By similarity)

Sequence caution: Sequence=DAA00303.1; Type=Erroneous initiation;

Secondary accessions: Q8N8Q0

Explore the universe of human proteins at neXtProt for OLIG3: NX_Q7RTU3

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q7RTU3

OLIG3 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_786923.1

ENSEMBL proteins:

ENSP00000356708

Human Recombinant Protein Products for OLIG3:

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	Uscn Proteins for OLIG3

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--

OLIG3 for ontologies About GeneDecksing

OLIG3 Antibody Products:

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	Uscn ELISAs and CLIAs for OLIG3

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

OLIG3 for domains About GeneDecksing

1 InterPro domain/family:

IPR011598 HLH_dom

Graphical View of Domain Structure for InterPro Entry Q7RTU3

ProtoNet protein and cluster: Q7RTU3

1 Blocks protein family: IPB001092 Basic helix-loop-helix dimerization domain bHLH

UniProtKB/Swiss-Prot: OLIG3_HUMAN, Q7RTU3

Similarity: Contains 1 bHLH (basic helix-loop-helix) domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: OLIG3_HUMAN, Q7RTU3

Function: May determine the distinct specification program of class A neurons in the dorsal part of the spinal cord and

suppress specification of class B neurons

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003677	DNA binding	IEA	--
GO:0046983	protein dimerization activity	IEA	--

OLIG3 for ontologies About GeneDecksing

Phenotypes:
6 MGI mutant phenotypes (inferred from 5 alleles) (MGI details for Olig3):

cellular	homeostasis/metabolism	mortality/aging	nervous system	no phenotypic analysis
respiratory system

OLIG3 for phenotypes About GeneDecksing

Animal Models:
Mouse knock-out Olig3^tm1Qiu for OLIG3

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for OLIG3

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat OLIG3
		8/41 QIAGEN miScript miRNA Assays for microRNAs that regulate OLIG3 (see all 41):
		hsa-miR-579 hsa-miR-19b-2* hsa-miR-200a hsa-miR-485-3p hsa-miR-605 hsa-miR-3074-3p hsa-miR-624 hsa-miR-507

		SwitchGear 3'UTR luciferase reporter plasmid: OLIG3 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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		GenScript: all cDNA clones in your preferred vector: OLIG3 (NM_175747)
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OLIG3

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Neural Crest Differentiation

Neural Crest Differentiation

1.00

1 BioSystems Pathway for OLIG3

Neural Crest Differentiation

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for OLIG3

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

1 Interacting protein for OLIG3 (Q7RTU3³ ENSP00000356708⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
TCF12	Q99081³, ENSP00000331057⁴	I2D: score=2 STRING: ENSP00000331057

About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006351	transcription, DNA-dependent	IEA	--
GO:0006355	regulation of transcription, DNA-dependent	IEA	--

OLIG3 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for OLIG3
Search CenterWatch for drugs/clinical trials and news about OLIG3

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for OLIG3 gene:

NM_175747.2

Unigene Cluster for OLIG3:

Oligodendrocyte transcription factor 3

Hs.195398 [show with all ESTs]

Unigene Representative Sequence: BC051352

1 Ensembl transcript including schematic representation, and UCSC links where relevant:

ENST00000367734(uc003qhp.1)

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat OLIG3
		8/41 QIAGEN miScript miRNA Assays for microRNAs that regulate OLIG3 (see all 41):
		hsa-miR-579 hsa-miR-19b-2* hsa-miR-200a hsa-miR-485-3p hsa-miR-605 hsa-miR-3074-3p hsa-miR-624 hsa-miR-507

		SwitchGear 3'UTR luciferase reporter plasmid: OLIG3 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for OLIG3 (see all 7) OriGene shRNA RFP: OLIG3 OriGene siRNA: OLIG3
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OLIG3
		Sirion Biotech Custom design and validation of potent shRNA sequences against OLIG3

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for OLIG3 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for OLIG3 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: OLIG3 (NM_175747)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for OLIG3
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OLIG3

Additional cDNA sequence:

AK096362.1 BC051352.1

1 DOTS entry:

DT.100019023

10 AceView cDNA sequences:

BC051352 AK096362 BX111291 NM_175747 BU855346 AI952817 BU556497 AI990825

CA337059 AI656498

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

OLIG3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CGGGGTTGGC

About this image

OLIG3 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Neuroectoderm cells (Generation of human ...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See OLIG3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for OLIG3

SOURCE GeneReport for Unigene cluster: Hs.195398

SABiosciences Custom PCR Arrays for OLIG3

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for OLIG3 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OLIG3

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OLIG3

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for OLIG3 gene from 4/13 species (see all 13) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	LOC100857919¹	oligodendrocyte transcription factor 3-like	83.76(n) 87.45(a)		100857919 XM_003640920.1 XP_003640968.1
tropical clawed frog (Xenopus tropicalis)	Amphibia	Str.11145²	Transcribed sequence with weak similarity to protein more	74.28(n)		137712979
zebrafish (Danio rerio)	Actinopterygii	olig3¹	oligodendrocyte transcription factor 3	73.33(n) 74.9(a)		566728 NM_001110393.1 NP_001103863.1
worm (Caenorhabditis elegans)	Secernentea	hlh-16⁶	Helix Loop Helix family member (hlh-16)	29(a)	1 → many	I(8767013-8768022)

ENSEMBL Gene Tree for OLIG3 (if available)
TreeFam Gene Tree for OLIG3 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for OLIG3 gene

BHLHE22² BHLHE23² OLIG1² OLIG2²

2 SIMAP similar genes for OLIG3 using alignment to 1 protein entry: OLIG3_HUMAN:

BHLHE23 OLIG2

OLIG3 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 6 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs150206651^1,2	C	--	137812866(+)	`AGTAT-/TTGACTAT TTTCTAAGAGTTGAC`	1	--	ds500¹		0	--	--	--	--
rs186175734^1,2		--	137813036(+)	`TTCCTG/TCCACT`	1	--	ds500¹		0	--	--	--	--
rs72987440^1,2	C	--	137813077(+)	`ATTCTC/TGAGTT`	1	--	ds500¹		0	--	--	--	--
rs9494788^1,2	F	--	137813078(+)	`TTCTCG/CAGTTT`	1	--	ds500¹		1		WA	118
rs56137793^1,2	C	--	137813095(+)	`GTCTGA/GTTACT`	1	--	ds500¹		3		WA NA	240
rs74345392^1,2	C,F	--	137813124(+)	`ATAGCA/GTAATA`	1	--	ds500¹		2		WA NA	238
rs183395771^1,2		--	137813179(+)	`AAATCA/GGCACC`	1	--	ds500¹		0	--	--	--	--
rs116121121^1,2	C,F	--	137813193(+)	`TTACCC/TATCCT`	1	--	ds500¹		1		WA	118
rs188929912^1,2		--	137813380(+)	`GAAACA/TCTGGT`	1	--	ut3¹		0	--	--	--	--
rs192702528^1,2		--	137813413(+)	`ATCAAG/TAATAT`	1	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for OLIG3 (137813336 - 137815531 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for OLIG3: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing OLIG3

DNA2.0 Custom Variant and Variant Library Synthesis for OLIG3

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

OLIG3 for disorders           About GeneDecksing

OMIM gene information: 609323    OMIM disorders: --

4 diseases for OLIG3:    About MalaCards

rheumatoid arthritis multiple sclerosis arthritis neuronitis

1 disease from the University of Copenhagen DISEASES database for OLIG3:

Rheumatoid arthritis

Human Genome Epidemiology (HuGE) Navigator: OLIG3 (8 documents)

Export disorders for OLIG3 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for OLIG3 gene, integrated from 9 sources (see all 18):
(articles sorted by number of sources associating them with OLIG3)

Utopia: connect your pdf to the dynamic
world of online information

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)^{1, 2} Mungall A.J.... Beck S. (2003)
Exhaustive identification of human class II basic helix-loop-helix proteins by virtual library screening. (PubMed id 14516699)^{1, 2} McLellan A.S.... Kealey T. (2002)
A protein array screen for Kaposi's sarcoma-associated herpesvirus LANA interactors links LANA to TIP60, PP2A activity, and telomere s hortening. (PubMed id 22379092)¹ Shamay M....Hayward S.D. (2012)
Genetic risk and a primary role for cell-mediated immu ne mechanisms in multiple sclerosis. (PubMed id 21833088)¹ ....Compston A. (2011)
Genetic variants in the prediction of rheumatoid arth ritis. (PubMed id 20439292)¹ van der Helm-van Mil A.H....Huizinga T.W. (2010)
A genetic marker at the OLIG3/TNFAIP3 locus associate s with methotrexate continuation in early inflammatory polyarthritis: results f rom the Norfolk Arthritis Register. (PubMed id 20921970)¹ Plant D....Thomson W. (2010)
A regulatory variant in CCR6 is associated with rheum atoid arthritis susceptibility. (PubMed id 20453841)¹ Kochi Y....Yamamoto K. (2010)
Genome-wide searching of rare genetic variants in WTC CC data. (PubMed id 20549515)¹ Feng T. and Zhu X. (2010)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 167826	HGNC: 18003	AceView: OLIG3	Ensembl:ENSG00000177468	euGenes: HUgn167826
ECgene: OLIG3	H-InvDB: OLIG3

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for OLIG3	Pharmacogenomics, SNPs, Pathways

Intellectual Property for OLIG3 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for OLIG3 gene:
Search GeneIP for patents involving OLIG3

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section

	Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
	EMD Millipore Mono- and Polyclonal Antibodies for the study of OLIG3
	Browse Small Molecules at EMD Millipore
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	OriGene Antibodies for OLIG3		OriGene shRNA RFP for OLIG3
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for OLIG3		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for OLIG3
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	OriGene Purified Protein for OLIG3		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat OLIG3
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing OLIG3
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	GenScript Custom Purified and Recombinant Proteins Services for OLIG3		GenScript cDNA clones with any tag delivered in your preferred vector for OLIG3
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	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OLIG3

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for OLIG3

Sirion Biotech Customized:

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GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 13 May 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes OLIG3 gene at Home site.

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OLIG3 Gene

oligodendrocyte transcription factor 3

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OLIG3 Gene

oligodendrocyte transcription factor 3

Aliasesfor OLIG3 gene

Summariesfor OLIG3 gene

Genomic Viewsfor OLIG3 gene

Proteinsfor OLIG3 gene

Protein Domains /Familiesfor OLIG3 gene

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for OLIG3 gene

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for OLIG3 gene

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for OLIG3 gene

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for OLIG3 gene

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Families
for OLIG3 gene

Function
for OLIG3 gene

Pathways & Interactions
for OLIG3 gene

Drugs & Compounds
for OLIG3 gene

Transcripts
for OLIG3 gene

Expression
for OLIG3 gene

Orthologs
for OLIG3 gene

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for OLIG3 gene

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for OLIG3 gene

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for OLIG3 gene

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for OLIG3 gene

Intellectual Property
for OLIG3 gene

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for OLIG3 gene