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OLIG1 Gene

protein-coding   GIFtS: 53
GCID: GC21P034442

Oligodendrocyte Transcription Factor 1

  See OLIG1-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Oligodendrocyte Transcription Factor 11 2     Basic Domain1
Oligodendrocyte Lineage Transcription Factor 11 2     Class B1
Oligodendrocyte-Specific BHLH Transcription Factor 11 2     Helix-Loop-Helix Protein1
Class B Basic Helix-Loop-Helix Protein 62 3     Basic Domain, Helix-Loop-Helix Protein, Class B, 62
Class E Basic Helix-Loop-Helix Protein 212 3     oligo12
BHLHB62 3     Oligo13
BHLHE212 3     bHLHb63
61     bHLHe213

External Ids:    HGNC: 169831   Entrez Gene: 1164482   Ensembl: ENSG000001842217   OMIM: 6063855   UniProtKB: Q8TAK63   

Export aliases for OLIG1 gene to outside databases

Previous GC identifers: GC21P031019 GC21P033362 GC21P033364 GC21P019853


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for OLIG1 Gene:
OLIG1 (oligodendrocyte transcription factor 1) is a protein-coding gene. Diseases associated with OLIG1 include astrocytoma. GO annotations related to this gene include protein dimerization activity. An important paralog of this gene is BHLHE22.

UniProtKB/Swiss-Prot: OLIG1_HUMAN, Q8TAK6
Function: Promotes formation and maturation of oligodendrocytes, especially within the brain. Cooperates with
OLIG2 to establish the pMN domain of the embryonic neural tube (By similarity)

Gene Wiki entry for OLIG1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000021.8  NC_018932.2  NT_011512.12  
Regulatory elements:
   Regulatory transcription factor binding sites in the OLIG1 gene promoter:
         AP-1   NRSF form 1   MyoD   NRSF form 2   Arnt   Ik-2   NF-Y   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidOLIG1 promoter sequence
   Search Chromatin IP Primers for OLIG1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat OLIG1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 21q22.11   Ensembl cytogenetic band:  21q22.11   HGNC cytogenetic band: 21q22.11

OLIG1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
OLIG1 gene location

GeneLoc information about chromosome 21         GeneLoc Exon Structure

GeneLoc location for GC21P034442:  view genomic region     (about GC identifiers)

Start:
34,442,450 bp from pter      End:
34,444,728 bp from pter
Size:
2,279 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: OLIG1_HUMAN, Q8TAK6 (See protein sequence)
Recommended Name: Oligodendrocyte transcription factor 1  
Size: 271 amino acids; 27905 Da
Sequence caution: Sequence=AAH26989.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=DAA01058.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: Q7RTS0

Explore the universe of human proteins at neXtProt for OLIG1: NX_Q8TAK6

Explore proteomics data for OLIG1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See OLIG1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_620450.2  
    ENSEMBL proteins: 
     ENSP00000371785   ENSP00000414840   ENSP00000331066  

    OLIG1 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for OLIG1

     
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    antibodies-online proteins for OLIG1 

     
    antibodies-online peptides for OLIG1

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    antibodies-online antibodies for OLIG1 (62 products) 

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    antibodies-online kits for OLIG1 (6 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    bHLH: Basic helix-loop-helix proteins

    1 InterPro protein domain:
     IPR011598 bHLH_dom

    Graphical View of Domain Structure for InterPro Entry Q8TAK6

    ProtoNet protein and cluster: Q8TAK6

    1 Blocks protein domain: IPB001092 Basic helix-loop-helix dimerization domain bHLH

    UniProtKB/Swiss-Prot: OLIG1_HUMAN, Q8TAK6
    Similarity: Contains 1 bHLH (basic helix-loop-helix) domain


    Find genes that share domains with OLIG1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: OLIG1_HUMAN, Q8TAK6
    Function: Promotes formation and maturation of oligodendrocytes, especially within the brain. Cooperates with
    OLIG2 to establish the pMN domain of the embryonic neural tube (By similarity)

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0005515protein binding IPI18923419
    GO:0046983protein dimerization activity IEA--
         
    Find genes that share ontologies with OLIG1           About GenesLikeMe


    Phenotypes:
         3 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Olig1):
     growth/size/body  mortality/aging  nervous system 

    Find genes that share phenotypes with OLIG1           About GenesLikeMe

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for OLIG1

    miRNA
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    5 qRT-PCR Assays for microRNAs that regulate OLIG1:
    hsa-miR-582-3p hsa-miR-3168 hsa-miR-4271 hsa-miR-7-2* hsa-miR-7-1*
    SwitchGear 3'UTR luciferase reporter plasmidOLIG1 3' UTR sequence
    Inhib. RNA
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    Addgene plasmids for OLIG1 

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    OLIG1_HUMAN, Q8TAK6: Nucleus (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytoskeleton1
    cytosol1
    endoplasmic reticulum1
    extracellular1
    mitochondrion1
    peroxisome1
    plasma membrane1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    Find genes that share ontologies with OLIG1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for OLIG1 About    
    See pathways by source

    SuperPathContained pathways About
    1Neural Crest Differentiation
    Neural Crest Differentiation


    1 BioSystems Pathway for OLIG1
        Neural Crest Differentiation



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for OLIG1
    Interactions:

        GeneGlobe Interaction Network for OLIG1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 15)

    Selected Interacting proteins for OLIG1 (Q8TAK61, 2, 3 ENSP000003310664) via UniProtKB, MINT, STRING, and/or I2D (see all 20)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SMAD2Q157961, 2, 3, ENSP000002621604EBI-3867416,EBI-1040141 MINT-7295493 MINT-7295480 I2D: score=1 STRING: ENSP00000262160
    CCNDBP1O952732, 3, ENSP000003002134MINT-8396226 I2D: score=1 STRING: ENSP00000300213
    CERS4Q9HA823, ENSP000002513634I2D: score=1 STRING: ENSP00000251363
    ID4P479283, ENSP000003679724I2D: score=1 STRING: ENSP00000367972
    ID2Q023633, ENSP000002340914I2D: score=1 STRING: ENSP00000234091
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated IEA--
    GO:0048663neuron fate commitment IEA--

    Find genes that share ontologies with OLIG1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for OLIG1



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for OLIG1 gene: 
    NM_138983.2  

    Unigene Cluster for OLIG1:

    Oligodendrocyte transcription factor 1
    Hs.56663  [show with all ESTs]
    Unigene Representative Sequence: BC033290
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000382348(uc002yqz.3) ENST00000426947 ENST00000498799 ENST00000333063

    miRNA
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    5 qRT-PCR Assays for microRNAs that regulate OLIG1:
    hsa-miR-582-3p hsa-miR-3168 hsa-miR-4271 hsa-miR-7-2* hsa-miR-7-1*
    SwitchGear 3'UTR luciferase reporter plasmidOLIG1 3' UTR sequence
    Inhib. RNA
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      QuantiTect SYBR Green Assays in human, mouse, rat OLIG1
      QuantiFast Probe-based Assays in human, mouse, rat OLIG1

    Additional mRNA sequence: 

    AB209791.1 AL355743.1 AL834450.1 BC011252.1 BC026989.1 BC033290.1 

    2 DOTS entries:

    DT.209886  DT.95172090 

    Selected AceView cDNA sequences (see all 73):

    AI479913 AW026386 BC026989 BM672942 AW292168 BK000278 AW298788 AI566858 
    AI272180 AW614560 AI359174 AI199664 NM_138983 AW071904 BC011252 AI498592 
    AW292625 AI214065 BG913504 BG913499 BE857379 AL355743 BC033290 AL834450 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    OLIG1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GACGCCCTGC
    OLIG1 Expression
    About this image


    OLIG1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Brain (Nervous System)    fully expand to see all 31 entries
             Oligodendrocyte Precursor Cells dP3 Neural Domain
             Thalamus
             Oligodendrocyte progenitor-like cells
             Fetal Neuronal Stem Cells (NSC)   
             Midbrain   
     
     Neural Tube (Nervous System)    fully expand to see all 14 entries
             Oligodendrocyte Precursor Cells dP3 Neural Domain
             Telencephalon
             brain/midbrain/lateral wall   
     
     Spinal Cord (Nervous System)    fully expand to see all 8 entries
             Oligodendrocyte Precursor Cells Spinal Cord White Matter
             Oligodendrocyte progenitor-like cells
     
     Oligodendrocytes (Nervous System)    fully expand to see all 5 entries
             Oligodendrocyte progenitor-like cells
     
     NULL (Uncategorized)
             Neural precursor spheres
    OLIG1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    OLIG1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.56663

    UniProtKB/Swiss-Prot: OLIG1_HUMAN, Q8TAK6
    Tissue specificity: Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while
    expression is weak to moderate in astrocytomas. Expression in glioblastomas is highly variable

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for OLIG1 gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Olig11 , 5 oligodendrocyte transcription factor 11, 5 84.56(n)1
    87.26(a)1
      16 (52.67 cM)5
    509141  NM_016968.41  NP_058664.21 
     912697725 
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia olig11 oligodendrocyte transcription factor 1 61.24(n)
    66.27(a)
      100487848  XM_004912143.1  XP_004912200.1 
    zebrafish
    (Danio rerio)
    Actinopterygii olig11 oligodendrocyte lineage transcription factor 1 59.65(n)
    59.21(a)
      100001484  NM_001020796.1  NP_001018632.1 
    worm
    (Caenorhabditis elegans)
    Secernentea hlh-166
    Protein HLH-16 (hlh-16) mRNA, complete cds
    28(a)
    1 → many
    I(8767019-8768028) WBGene00001960


    ENSEMBL Gene Tree for OLIG1 (if available)
    TreeFam Gene Tree for OLIG1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for OLIG1 gene
    BHLHE222  OLIG32  BHLHE232  OLIG22  

    Find genes that share paralogs with OLIG1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for OLIG1 (see all 69)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 21 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs752506161,2
    C,F--34440652(+) TCTCTC/GTCCCA 1 -- us2k11Minor allele frequency- G:0.06WA 118
    rs99837551,2
    C,F--34440669(+) GGCCCC/GCAGCA 1 -- us2k19Minor allele frequency- G:0.28NA WA EA 370
    rs1142975261,2
    F--34440678(+) CACCAC/TGTCCA 1 -- us2k11Minor allele frequency- T:0.02WA 118
    rs1829346061,2
    --34440712(+) GGCAGA/GAGATC 1 -- us2k10--------
    rs1403562471,2
    --34440771(+) TTAGAA/GCATTG 1 -- us2k10--------
    rs65171401,2
    C,F,A,H--34440850(+) TCCAGG/CACACA 1 -- us2k15Minor allele frequency- C:0.04NS EA WA 534
    rs1499441751,2
    --34440877(+) CTGTGA/CTAGGC 1 -- us2k10--------
    rs799502411,2
    --34440885(+) GGCTTC/TAGGAA 1 -- us2k10--------
    rs1883825671,2
    --34441056(+) GCAAGG/TTTGGA 1 -- us2k10--------
    rs1918314301,2
    --34441232(+) AAGTTA/GTAGTA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for OLIG1 (34442450 - 34444728 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for OLIG1: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing OLIG1
    DNA2.0 Custom Variant and Variant Library Synthesis for OLIG1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 606385    OMIM disorders: --

    1 disease for OLIG1:    
    About MalaCards
    astrocytoma


    Find genes that share disorders with OLIG1           About GenesLikeMe

    10 Novoseek inferred disease relationships for OLIG1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    oligodendroglial tumors 79.5 2 12924709 (1), 15164981 (1)
    oligodendroglioma 76 5 14989603 (2), 14730454 (1), 15164981 (1)
    anaplastic oligodendroglioma 67.8 2 14730454 (1), 14575240 (1)
    anaplastic astrocytoma 60.7 2 14730454 (1), 14575240 (1)
    astrocytoma 53 1 14730454 (1)
    demyelination 52.6 1 19318112 (1)
    brain tumors 43.5 4 14989603 (2), 12924709 (1)
    glioblastoma 42.7 3 14730454 (1), 14575240 (1), 15164981 (1)
    glioma 30.6 3 14575240 (2), 14730454 (1)
    tumors 11.3 1 12924709 (1)

    Genetic Association Database (GAD): OLIG1
    Human Genome Epidemiology (HuGE) Navigator: OLIG1 (1 document)

    Export disorders for OLIG1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for OLIG1 gene, integrated from 10 sources (see all 45):
    (articles sorted by number of sources associating them with OLIG1)
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    1. Oligodendrocyte lineage genes (OLIG) as molecular markers for human glial brain tumors. (PubMed id 11526205)1, 2, 3 Lu Q.R.... Black P.M. (Proc. Natl. Acad. Sci. U.S.A. 2001)
    2. A genetic family-based association study of OLIG2 in obsessive-compulsive disorder. (PubMed id 17283288)1, 4, 9 Stewart S.E....Pauls D.L. (Arch. Gen. Psychiatry 2007)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Exhaustive identification of human class II basic helix-loop-helix proteins by virtual library screening. (PubMed id 14516699)1, 2 McLellan A.S.... Kealey T. (Mech. Dev. 2002)
    5. Identification of a novel family of oligodendrocyte lineage-specific basic helix-loop-helix transcription factors. (PubMed id 10719889)1, 2 Zhou Q.... Anderson D.J. (Neuron 2000)
    6. The DNA sequence of human chromosome 21. (PubMed id 10830953)1, 2 Hattori M.... Yaspo M.-L. (Nature 2000)
    7. Olig transcription factors are expressed in oligodendrocyte and neuronal cells in human fetal CNS. (PubMed id 16267213)1, 9 Jakovcevski I. and Zecevic N. (J. Neurosci. 2005)
    8. Oligodendroglial transcription factor (OLIG1 and OLIG2) mutations are not associated with Pelizaeus-Merzbacher-like leukodystrophy. (PubMed id 17171653)1, 9 Ruf N....Uhlenberg B. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2007)
    9. An Id-like molecule, HHM, is a synexpression group-restricted regulator of TGF-beta signalling. (PubMed id 18923419)1, 9 Ikushima H....Miyazono K. (EMBO J. 2008)
    10. Dynamic expression of basic helix-loop-helix Olig family members: implication of Olig2 in neuron and oligodendrocyte differentiation and identification of a new member, Olig3. (PubMed id 11091082)1, 9 Takebayashi H....Nabeshima Y. (Mech. Dev. 2000)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 116448 HGNC: 16983 AceView: OLIG1 Ensembl:ENSG00000184221 euGenes: HUgn116448
    ECgene: OLIG1 H-InvDB: OLIG1

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for OLIG1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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    Patent Information for OLIG1 gene:
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    GeneCards and IP:
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