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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

OLFML3 Gene

protein-coding   GIFtS: 54
GCID: GC01P114522

Olfactomedin-Like 3

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Olfactomedin-Like 31 2
HNOEL-iso2 3
hOLF442 3
OLF442
Olfactomedin-Like Protein 32

External Ids:    HGNC: 249561   Entrez Gene: 569442   Ensembl: ENSG000001167747   OMIM: 6100885   UniProtKB: Q9NRN53   

Export aliases for OLFML3 gene to outside databases

Previous GC identifers: GC01P113821 GC01P114234 GC01P114323 GC01P112380


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for OLFML3 Gene: 
OLFML3 (olfactomedin-like 3) is a protein-coding gene. Diseases associated with OLFML3 include glaucoma. An important paralog of this gene is GLDN.

UniProtKB/Swiss-Prot: OLFL3_HUMAN, Q9NRN5
Function: Secreted scaffold protein that plays an essential role in dorsoventral patterning during early
development. Stabilizes axial formation by restricting chordin (CHRD) activity on the dorsal side. Acts by
facilitating the association between the tolloid proteases and their substrate chordin (CHRD), leading to enhance
chordin (CHRD) degradation (By similarity). May have matrix-related function involved in placental and embryonic
development, or play a similar role in other physiological processes

Gene Wiki entry for OLFML3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_032977.9  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the OLFML3 gene promoter:
         E2F-4   E2F-3a   E2F-5   MAZR   E2F-2   YY1   Evi-1   RORalpha1   E2F   E2F-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidOLFML3 promoter sequence
   Search SABiosciences Chromatin IP Primers for OLFML3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OLFML3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p13.2   Ensembl cytogenetic band:  1p13.2   HGNC cytogenetic band: 1p13.1

OLFML3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
OLFML3 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P114522:  view genomic region     (about GC identifiers)

Start:
114,522,030 bp from pter      End:
114,524,876 bp from pter
Size:
2,847 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: OLFL3_HUMAN, Q9NRN5 (See protein sequence)
Recommended Name: Olfactomedin-like protein 3 precursor  
Size: 406 amino acids; 46010 Da
Subcellular location: Secreted
Secondary accessions: Q53FR1 Q53HV9 Q5SQL6 Q69AX9 Q8NBJ2
Alternative splicing: 3 isoforms:  Q9NRN5-1   Q9NRN5-2   Q9NRN5-3   

Explore the universe of human proteins at neXtProt for OLFML3: NX_Q9NRN5

Explore proteomics data for OLFML3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9NRN5

  • OLFML3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    OLFML3 Protein Expression
    REFSEQ proteins: NP_064575.1  
    ENSEMBL proteins: 
     ENSP00000358564   ENSP00000322273   ENSP00000376977  

    Human Recombinant Protein Products for OLFML3: 
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    Novus Biologicals OLFML3 Protein
    Novus Biologicals OLFML3 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for OLFML3 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--

    OLFML3 for ontologies           About GeneDecksing



    OLFML3 Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR003112 Olfac-like

    Graphical View of Domain Structure for InterPro Entry Q9NRN5

    ProtoNet protein and cluster: Q9NRN5

    1 Blocks protein domain: IPB003112 Olfactomedin-like

    UniProtKB/Swiss-Prot: OLFL3_HUMAN, Q9NRN5
    Similarity: Belongs to the OLFML3 family
    Similarity: Contains 1 olfactomedin-like domain


    OLFML3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: OLFL3_HUMAN, Q9NRN5
    Function: Secreted scaffold protein that plays an essential role in dorsoventral patterning during early
    development. Stabilizes axial formation by restricting chordin (CHRD) activity on the dorsal side. Acts by
    facilitating the association between the tolloid proteases and their substrate chordin (CHRD), leading to enhance
    chordin (CHRD) degradation (By similarity). May have matrix-related function involved in placental and embryonic
    development, or play a similar role in other physiological processes

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    OLFML3 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for OLFML3:
     Decreased Hepatitis C virus re 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Olfml3):
     normal 

    OLFML3 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for OLFML3 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for OLFML3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for OLFML3 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for OLFML3 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat OLFML3
    4 QIAGEN miScript miRNA Assays for microRNAs that regulate OLFML3:
    hsa-miR-1290 hsa-miR-155 hsa-miR-876-5p hsa-miR-3167
    SwitchGear 3'UTR luciferase reporter plasmidOLFML3 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Gene Editing
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    Sirion Biotech Customized adenovirus for overexpression of OLFML3

    Clone
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: OLFML3 (NM_020190)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OLFML3
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                         Customized lentivirus expression plasmids for stable overexpression of OLFML3 

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    Search LifeMap BioReagents cell lines for OLFML3
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OLFML3


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for OLFML3

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    5/6 Interacting proteins for OLFML3 (Q9NRN52, 3 ENSP000003222734) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CKMT2P175402, 3MINT-63516 I2D: score=5 
    FEZ1Q996892, 3MINT-65615 I2D: score=5 
    HSPB3Q129882, 3MINT-64109 I2D: score=5 
    SETDB1Q150472, 3MINT-65614 I2D: score=5 
    MYOCQ999723, ENSP000000375024I2D: score=1 STRING: ENSP00000037502
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007275multicellular organismal development IEA--

    OLFML3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for OLFML3 (OLFL3)

    Search CenterWatch for drugs/clinical trials and news about OLFML3 / OLFL3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for OLFML3 gene: 
    NM_020190.2  

    Unigene Cluster for OLFML3:

    Olfactomedin-like 3
    Hs.9315  [show with all ESTs]
    Unigene Representative Sequence: AK075544
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000369551(uc001eer.1 uc001ees.1) ENST00000320334 ENST00000491700(uc001eet.1)
    ENST00000393300
    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat OLFML3
    4 QIAGEN miScript miRNA Assays for microRNAs that regulate OLFML3:
    hsa-miR-1290 hsa-miR-155 hsa-miR-876-5p hsa-miR-3167
    SwitchGear 3'UTR luciferase reporter plasmidOLFML3 3' UTR sequence
    Inhib. RNA
    Products:
         
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    OriGene ORF clones in mouse, rat for OLFML3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: OLFML3 (NM_020190)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for OLFML3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OLFML3
    Sirion Biotech Customized lentivirus for stable overexpression of OLFML3 
                         Customized lentivirus expression plasmids for stable overexpression of OLFML3 
    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OLFML3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OLFML3

    Additional mRNA sequence: 

    AF201945.1 AK075353.1 AK075369.1 AK075479.1 AK075544.1 AK092766.1 AK222471.1 AK223221.1 
    AK297902.1 AY358954.1 AY464015.1 BC009920.2 

    19 DOTS entries:

    DT.317653  DT.100673977  DT.100786765  DT.121415544  DT.100786757  DT.121415557  DT.97809428  DT.100023911 
    DT.100786769  DT.121415563  DT.121415565  DT.100710650  DT.121415523  DT.100720197  DT.100786759  DT.100786770 
    DT.121415535  DT.121415541  DT.121415545 

    24/360 AceView cDNA sequences (see all 360):

    CB149425 BU628589 CR608635 CR613617 BU845799 BP380349 CR599952 AI903965 
    CA392846 BP375760 BI768037 CA423413 BP374473 BQ067459 AA302922 CR596335 
    BP380366 CR610849 BU855834 BP378996 AL544708 AI869993 BP374137 CR615262 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for OLFML3 (see all 6)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b · 4c ^ 5a · 5b
    SP1:                    -                             -               
    SP2:              -     -                             -               
    SP3:              -     -                                             
    SP4:                                                                  
    SP5:              -                                                   


    ECgene alternative splicing isoforms for OLFML3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    OLFML3 expression in normal human tissues (normalized intensities)      OLFML3 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCAACAAATT
    OLFML3 Expression
    About this image


    OLFML3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/20 selected tissues (see all 20) fully expand
     
     Lower Urinary Tract (Urinary System)    fully expand to see all 7 entries
             Ureter
             visceral organ   
     
     Kidney (Urinary System)    fully expand to see all 5 entries
             Metanephros
             visceral organ/metanephros/pelvis   
     
     Inner Cell Mass (Early Embryonic Tissues)    fully expand to see all 4 entries
             Line H9 (WA09)
     
     Endothelium (Cardiovascular System)    fully expand to see all 2 entries
             Endothelial progenitor cells ( Derivation and purification of endothelial precursor...
             Human Villous Capillary Endothelial Cells (HVCEC)   
     
     Fibroblast
             Detroit 551
             BH2 Dermal Fibroblasts   

    See OLFML3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for OLFML3

    SOURCE GeneReport for Unigene cluster: Hs.9315

    UniProtKB/Swiss-Prot: OLFL3_HUMAN, Q9NRN5
    Tissue specificity: Abundant in placenta, moderate in liver and heart, whereas fairly weak in other tissues
    examined. On term placenta, mainly localized extracellularly surrounding the syncytiotrophoblastic cells and very
    rarely expressed in the maternal decidua layer

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OLFML3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for OLFML3 gene from 6/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Olfml31 , 5 olfactomedin-like 31, 5 89(n)1
    94.09(a)1
      3 (45.52 cM)5
    995431  NM_133859.21  NP_598620.21 
     1037222225 
    chicken
    (Gallus gallus)
    Aves OLFML31 olfactomedin-like 3 67.18(n)
    65.47(a)
      419882  NM_001040018.1  NP_001035107.1 
    lizard
    (Anolis carolinensis)
    Reptilia OLFML36
    olfactomedin-like 3
    65(a)
    1 ↔ 1
    4(129721245-129733599)
    zebrafish
    (Danio rerio)
    Actinopterygii wufb02c052 Transcribed sequence with weak similarity to protein more 72.75(n)    57092311 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG68676
    --
    7(a)
    1 → many
    X(17917903-17922294)
    worm
    (Caenorhabditis elegans)
    Secernentea cof-26
    unc-1226
    Protein UNC-122
    12(a)
    10(a)
    many ↔ many
    many ↔ many
    I(6250571-6252821)
    I(14872162-14875378)


    ENSEMBL Gene Tree for OLFML3 (if available)
    TreeFam Gene Tree for OLFML3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for OLFML3 gene
    GLDN2  OLFM32  OLFML2A2  OLFM12  OLFM42  OLFM22  MYOC2  OLFML2B2  
    OLFML12  
    2 SIMAP similar genes for OLFML3 using alignment to 2 protein entries:     OLFL3_HUMAN (see all proteins):
    DKFZp686H1812    OLFML1

    OLFML3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/168 SNPs in OLFML3 are shown (see all 168)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1424736911,2
    --114521060(+) ACCACA/GACCAA 1 -- us2k10--------
    rs800810231,2
    C,F--114521107(+) GAAGTC/TAGAAT 1 -- us2k11Minor allele frequency- T:0.04NA 120
    rs1419901021,2
    C--114521136(+) ACAAC-/ATATATA 1 -- us2k10--------
    rs789051981,2
    C,F--114521158(+) ATTCCG/ACCCCC 1 -- us2k11Minor allele frequency- A:0.04WA 118
    rs1887388481,2
    --114521188(+) AGTAAA/GTTAGT 1 -- us2k10--------
    rs1807707791,2
    --114521200(+) TGAACC/TCACTG 1 -- us2k10--------
    rs1165560741,2
    C,F--114521303(+) AGACGA/TTCGAG 1 -- us2k11Minor allele frequency- T:0.04WA 118
    rs2017731051,2
    --114521334(+) GACCT-/GGTTTT 1 -- us2k10--------
    rs1112997951,2
    C--114521336(+) ACCTG-/TTTTTT 1 -- us2k11Minor allele frequency- T:0.00CSA 2
    rs618191901,2
    C--114521353(+) TTTTAA/TTCTCA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for OLFML3 (114522030 - 114524876 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for OLFML3:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv23869CNV Loss19812545

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 610088    OMIM disorders: --

    2 diseases for OLFML3:    About MalaCards
    glaucoma    


    OLFML3 for disorders           About GeneDecksing

    Genetic Association Database (GAD): OLFML3

    Export disorders for OLFML3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for OLFML3 gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with OLFML3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. hOLF44, a secreted glycoprotein with distinct expression pattern, belongs to an uncharacterized olfactomedin-like subfamily newly identified by phylogenetic analysis. (PubMed id 15280020)1, 2, 9 Zeng L.-C....Ma W.-J. (2004)
    2. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    3. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (2005)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    7. Olfactomedin-like 3 (OLFML3) gene expression in baboon and human ocular tissues: cornea, lens, uvea, and retina. (PubMed id 23398349)1 Rodriguez-Sanchez I.P.... Barrera-Saldana H.A. (2013)
    8. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (2012)
    9. The SH3 domain of postsynaptic density 95 mediates inf lammatory pain through phosphatidylinositol-3-kinase recruitment. (PubMed id 20467438)1 Arbuckle M.I....Grant S.G. (2010)
    10. The identification of myocilin-associated proteins in the human trabecular meshwork. (PubMed id 16289162)1 Fautsch M.P....Johnson D.H. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 56944 HGNC: 24956 AceView: OLFML3 Ensembl:ENSG00000116774 euGenes: HUgn56944
    ECgene: OLFML3 H-InvDB: OLFML3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for OLFML3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for OLFML3 gene:
    Search GeneIP for patents involving OLFML3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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