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OLFML2B Gene

protein-coding   GIFtS: 50
GCID: GC01M161952

Olfactomedin-Like 2B

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Olfactomedin-Like 2B1 2
Olfactomedin-Like Protein 2B2
photomedin-22
Photomedin-23

External Ids:    HGNC: 245581   Entrez Gene: 259032   Ensembl: ENSG000001627457   UniProtKB: Q68BL83   

Export aliases for OLFML2B gene to outside databases

Previous GC identifers: GC01M159141 GC01M158684 GC01M160219 GC01M133197


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for OLFML2B Gene:
OLFML2B (olfactomedin-like 2B) is a protein-coding gene. Diseases associated with OLFML2B include atherosclerosis, and cerebritis. GO annotations related to this gene include extracellular matrix binding. An important paralog of this gene is GLDN.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000001.11  NT_004487.20  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the OLFML2B gene promoter:
         RFX1   AML1a   SREBP-1c   Nkx2-5   GATA-1   SREBP-1b   MEF-2A   AREB6   SREBP-1a   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidOLFML2B promoter sequence
   Search Chromatin IP Primers for OLFML2B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat OLFML2B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q23.3   Ensembl cytogenetic band:  1q23.3   HGNC cytogenetic band: 1q23.1

OLFML2B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
OLFML2B gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M161952:  view genomic region     (about GC identifiers)

Start:
161,952,982 bp from pter      End:
161,993,644 bp from pter
Size:
40,663 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: OLM2B_HUMAN, Q68BL8 (See protein sequence)
Recommended Name: Olfactomedin-like protein 2B precursor  
Size: 750 amino acids; 83999 Da
Subunit: Homodimer. Binds to heparin and chondroitin sulfate E (By similarity)
Sequence caution: Sequence=CAH71496.1; Type=Erroneous gene model prediction;
Secondary accessions: B7ZA39 Q5VU96 Q6NX46 Q86X11 Q9Y3X6
Alternative splicing: 2 isoforms:  Q68BL8-1   Q68BL8-2   

Explore the universe of human proteins at neXtProt for OLFML2B: NX_Q68BL8

Explore proteomics data for OLFML2B at MOPED

Post-translational modifications: 

  • O-glycosylated and N-glycosylated (By similarity)1
  • Glycosylation2 at Asn187, Asn213, Thr343, Thr346, Ser357, Thr358, Thr361, Asn695
  • Modification sites at PhosphoSitePlus

  • See OLFML2B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_056256.1  
    ENSEMBL proteins: 
     ENSP00000436707   ENSP00000294794   ENSP00000435212   ENSP00000356917   ENSP00000356915  

    OLFML2B Human Recombinant Protein Products:

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    OriGene Protein Over-expression Lysate for OLFML2B
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    Novus Biologicals OLFML2B Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for OLFML2B

    OLFML2B Antibody Products:

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    Novus Biologicals OLFML2B Antibodies
    Abcam antibodies for OLFML2B
    Cloud-Clone Corp. Antibodies for OLFML2B
    Search ThermoFisher Antibodies for OLFML2B
    LSBio Antibodies in human, mouse, rat for OLFML2B

    OLFML2B Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for OLFML2B
    Cloud-Clone Corp. CLIAs for OLFML2B


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR003112 Olfac-like

    Graphical View of Domain Structure for InterPro Entry Q68BL8

    ProtoNet protein and cluster: Q68BL8

    1 Blocks protein domain: IPB003112 Olfactomedin-like

    UniProtKB/Swiss-Prot: OLM2B_HUMAN, Q68BL8
    Similarity: Contains 1 olfactomedin-like domain


    OLFML2B for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0050840extracellular matrix binding IEA--
         
    OLFML2B for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for OLFML2B:
     G0/1 arrest  Increased G1 DNA content 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for OLFML2B
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for OLFML2B

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for OLFML2B
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for OLFML2B

    miRNA
    Products:
        
    miRTarBase miRNAs that target OLFML2B:
    hsa-mir-30b-5p (MIRT046128)

    Block miRNA regulation of human, mouse, rat OLFML2B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate OLFML2B (see all 15):
    hsa-miR-18a hsa-miR-769-5p hsa-miR-634 hsa-miR-1283 hsa-miR-449c* hsa-miR-323b-3p hsa-miR-624 hsa-miR-507
    SwitchGear 3'UTR luciferase reporter plasmidOLFML2B 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for OLFML2B
    Predesigned siRNA for gene silencing in human, mouse, rat OLFML2B

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for OLFML2B

    Clone
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    OriGene clones in human, mouse for OLFML2B (see all 6)
    OriGene ORF clones in mouse, rat for OLFML2B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: OLFML2B (NM_015441)
    Sino Biological Human cDNA Clone for OLFML2B
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for OLFML2B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OLFML2B

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for OLFML2B 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OLFML2B


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    OLM2B_HUMAN, Q68BL8: Secreted (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular2
    cytosol1
    endoplasmic reticulum1
    golgi apparatus1
    lysosome1
    nucleus1
    plasma membrane1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--
    GO:0031012extracellular matrix IEA--

    OLFML2B for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for OLFML2B
    Interactions:

        Search GeneGlobe Interaction Network for OLFML2B

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0030198extracellular matrix organization IEA--

    OLFML2B for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for OLFML2B (OLM2B)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for OLFML2B gene: 
    NM_015441.1  

    Unigene Cluster for OLFML2B:

    Olfactomedin-like 2B
    Hs.507515  [show with all ESTs]
    Unigene Representative Sequence: BC067274
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000533556 ENST00000294794(uc001gbt.3 uc001gbu.3 uc010pkq.2)
    ENST00000525589 ENST00000367940 ENST00000367938
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat OLFML2B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate OLFML2B (see all 15):
    hsa-miR-18a hsa-miR-769-5p hsa-miR-634 hsa-miR-1283 hsa-miR-449c* hsa-miR-323b-3p hsa-miR-624 hsa-miR-507
    SwitchGear 3'UTR luciferase reporter plasmidOLFML2B 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for OLFML2B
    Predesigned siRNA for gene silencing in human, mouse, rat OLFML2B
    Clone
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    OriGene clones in human, mouse for OLFML2B (see all 6)
    OriGene ORF clones in mouse, rat for OLFML2B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: OLFML2B (NM_015441)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for OLFML2B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OLFML2B
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for OLFML2B
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat OLFML2B
      QuantiTect SYBR Green Assays in human, mouse, rat OLFML2B
      QuantiFast Probe-based Assays in human, mouse, rat OLFML2B

    Additional mRNA sequence: 

    AB119054.1 AK301499.1 AK316154.1 AL050137.1 BC047472.1 BC067274.1 BX648975.1 

    2 DOTS entries:

    DT.99964182  DT.100694438 

    Selected AceView cDNA sequences (see all 98):

    BE645614 BM719150 AW137901 BE328022 AA489716 AA988383 NM_015441 BC067274 
    CR600954 AW581166 AB119054 AI348665 AI697367 AI417055 BU627874 BU622765 
    AI393861 BX648975 AI659721 BQ673977 AW079107 AI419309 AI537381 BQ668721 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    OLFML2B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCATCTTTGC
    OLFML2B Expression
    About this image


    OLFML2B expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Cartilage (Muscoskeletal System)    fully expand to see all 3 entries
             Intervertebral Disc Nucleus Pulposus Cells Nucleus Pulposus
             Nucleus Pulposus
             TGFbeta3+BMP7-induced chondrocytes
     
     Primitive Streak (Early Embryonic Tissues)
             Notochord
     
     Bone (Muscoskeletal System)
             TGFbeta3+BMP7-induced chondrocytes
     
     Blood (Hematopoietic System)
             Granulocytes Peripheral Blood
     
     Brain (Nervous System)
             Cerebral Cortex
    OLFML2B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    OLFML2B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.507515
        Custom PCR Arrays for OLFML2B
    Primer
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    QuantiFast Probe-based Assays in human, mouse, rat OLFML2B
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OLFML2B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for OLFML2B gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Olfml2b1 , 5 olfactomedin-like 2B1, 5 84.32(n)1
    84.32(a)1
      1 (76.95 cM)5
    3200781  NM_177068.41  NP_796042.31 
     1706445325 
    chicken
    (Gallus gallus)
    Aves OLFML2B1 olfactomedin-like 2B 71.03(n)
    71.97(a)
      424366  XM_422209.4  XP_422209.4 
    lizard
    (Anolis carolinensis)
    Reptilia OLFML2B6
    olfactomedin-like 2B
    61(a)
    1 ↔ 1
    4(71034684-71063536)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia olfml2b1 olfactomedin-like 2B 64.36(n)
    66.03(a)
      100498044  XM_004913779.1  XP_004913836.1 
    zebrafish
    (Danio rerio)
    Actinopterygii olfml2ba1 olfactomedin-like 2Ba 63.77(n)
    63.52(a)
      557997  NM_001044849.1  NP_001038314.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG68676
    --
    11(a)
    1 → many
    X(17917903-17922294)
    worm
    (Caenorhabditis elegans)
    Secernentea cof-26
    unc-1226
    Protein UNC-122 (unc-122) mRNA, complete cds
    21(a)
    18(a)
    many ↔ many
    many ↔ many
    I(6250571-6252821) WBGene00000583
    I(14872162-14875378) WBGene00006845


    ENSEMBL Gene Tree for OLFML2B (if available)
    TreeFam Gene Tree for OLFML2B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for OLFML2B gene
    GLDN2  OLFM32  OLFML32  OLFML2A2  OLFM12  OLFM42  OLFM22  MYOC2  
    OLFML12  
    7 SIMAP similar genes for OLFML2B using alignment to 4 protein entries:     OLM2B_HUMAN (see all proteins):
    FLJ00237    OLFM2    OLFM1    MYOC    OLFM3    LPHN1
    OLFML2A

    OLFML2B for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for OLFML2B (see all 1000)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1434373051,2
    C--133240138(+) ATGGG-/AGGGGG 1 -- us2k10--------
    rs46563461,2
    C,F,A,H--133240148(+) GGGCCG/ATGGCA 1 -- us2k113Minor allele frequency- A:0.14NA WA CSA EA 380
    rs1499675951,2
    C--133240261(+) CCACCA/GGCATA 1 -- us2k10--------
    rs1450877511,2
    --133240264(+) CCAGCA/GTAATT 1 -- us2k10--------
    rs1150237051,2
    C,F--133240349(+) CCTTTG/ATGGGT 1 -- us2k11Minor allele frequency- A:0.08WA 118
    rs1410358381,2
    C--133240356(+) GGGTTG/TTTTTG 1 -- us2k10--------
    rs792678601,2
    C,F--133240388(+) AGACTA/GTAAAT 1 -- us2k11Minor allele frequency- G:0.04NA 120
    rs1914002001,2
    --133240420(+) TAGTTG/TTGCTC 1 -- us2k10--------
    rs1442206851,2
    --161952574(+) TGATTA/GAGAAC 1 -- int10--------
    rs1477643481,2
    --161952592(+) GGAAGG/TGTGGG 1 -- int10--------

    HapMap Linkage Disequilibrium report for OLFML2B (161952982 - 161993644 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for OLFML2B:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv3287CNV Insertion18451855
    nsv831747CNV Loss17160897
    nsv470744CNV Gain18288195
    nsv464206CNV Gain19166990
    esv33393CNV Gain+Loss17666407

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing OLFML2B
    DNA2.0 Custom Variant and Variant Library Synthesis for OLFML2B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    2 diseases for OLFML2B:    
    About MalaCards
    atherosclerosis    cerebritis


    OLFML2B for disorders           About GeneDecksing

    Genetic Association Database (GAD): OLFML2B
    Human Genome Epidemiology (HuGE) Navigator: OLFML2B (2 documents)

    Export disorders for OLFML2B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for OLFML2B gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with OLFML2B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    2. Integrative predictive model of coronary artery calcification in atherosclerosis. (PubMed id 19948975)1, 4 McGeachie M....Ramoni M.F. (Circulation 2009)
    3. Common genetic variation near the phospholamban gene is associated with cardiac repolarisation: meta-analysis of three genome-wide association studies. (PubMed id 19587794)1, 4 Nolte I.M....Jamshidi Y. (PLoS ONE 2009)
    4. Genome-wide association and population genetic analysis of C-reactive protein in African American and Hispanic American women. (PubMed id 22939635)1 Reiner A.P....Tang H. (Am. J. Hum. Genet. 2012)
    5. Common variants at ten loci modulate the QT interval duration in the QTSCD Study. (PubMed id 19305409)4 Pfeufer A.... Chakravarti A. (Nat. Genet. 2009)
    6. A genome-wide association scan of RR and QT interval duration in 3 European genetically isolated populations: the EUROSPAN project. (PubMed id 20031603)4 Marroni F....Pramstaller P.P. (Circ Cardiovasc Genet 2009)
    7. Genome-scale RNAi screen for host factors required for HIV replication. (PubMed id 18976975)1 Zhou H....Espeseth A.S. (amp 2008)
    8. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    9. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (Nature 2006)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 25903 HGNC: 24558 AceView: OLFML2B Ensembl:ENSG00000162745 euGenes: HUgn25903
    ECgene: OLFML2B H-InvDB: OLFML2B

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for OLFML2B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for OLFML2B gene:
    Search GeneIP for patents involving OLFML2B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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