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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

OLFML2B Gene

protein-coding GIFtS: 47
GCID: GC01M161952

olfactomedin-like 2B

Explore 1 disease affiliated with
OLFML2B via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Olfactomedin-Like 2B¹ ²
DKFZP586L151¹
RP11-227F8.1²
Olfactomedin-Like Protein 2B²
Photomedin-2³
Photomedin-2³

External Ids:	HGNC: 24558¹	Entrez Gene: 25903²	Ensembl: ENSG00000162745⁷	UniProtKB: Q68BL8³

Export aliases for OLFML2B gene to outside databases

Previous GC identifers: GC01M159141 GC01M158684 GC01M160219 GC01M133197

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000001.10 NC_018912.1 NT_004487.19

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the OLFML2B gene promoter:
RFX1 AML1a SREBP-1c Nkx2-5 GATA-1 SREBP-1b MEF-2A AREB6 SREBP-1a aMEF-2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: OLFML2B promoter sequence

Search SABiosciences Chromatin IP Primers for OLFML2B

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OLFML2B

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q23.3 Ensembl cytogenetic band: 1q23.3 HGNC cytogenetic band: 1q23.1

OLFML2B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
OLFML2B gene location

GeneLoc information about chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01M161952: view genomic region (about GC identifiers)

Start:	161,952,982 bp from pter	End:	161,993,644 bp from pter
Size:	40,663 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: OLM2B_HUMAN, Q68BL8 (See protein sequence)

Recommended Name: Olfactomedin-like protein 2B precursor

Size: 750 amino acids; 83999 Da

Subunit: Homodimer. Binds to heparin and chondroitin sulfate E (By similarity)

Subcellular location: Secreted (By similarity)

Sequence caution: Sequence=CAH71496.1; Type=Erroneous gene model prediction;

Secondary accessions: B7ZA39 Q5VU96 Q6NX46 Q86X11 Q9Y3X6

Alternative splicing: 2 isoforms: Q68BL8-1 Q68BL8-2

Explore the universe of human proteins at neXtProt for OLFML2B: NX_Q68BL8

Post-translational modifications:

O-glycosylated and N-glycosylated (By similarity)¹

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q68BL8

OLFML2B Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_056256.1

ENSEMBL proteins:

ENSP00000436707 ENSP00000294794 ENSP00000435212 ENSP00000356917 ENSP00000356915

Human Recombinant Protein Products for OLFML2B:

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	Novus Biologicals OLFML2B Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for OLFML2B

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	IEA	--
GO:0031012	extracellular matrix	IEA	--

OLFML2B for ontologies About GeneDecksing

OLFML2B Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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	GenScript Custom Superior Antibodies Services for OLFML2B
	Novus Biologicals OLFML2B Antibodies
	Abcam antibodies for OLFML2B
	Uscn Antibodies for OLFML2B
	Search ThermoFisher Antibodies for OLFML2B

Assay Products for OLFML2B:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for OLFML2B
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for OLFML2B

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

OLFML2B for domains About GeneDecksing

1 InterPro domain/family:

IPR003112 Olfac-like

Graphical View of Domain Structure for InterPro Entry Q68BL8

ProtoNet protein and cluster: Q68BL8

1 Blocks protein family: IPB003112 Olfactomedin-like

UniProtKB/Swiss-Prot: OLM2B_HUMAN, Q68BL8

Similarity: Contains 1 olfactomedin-like domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0050840	extracellular matrix binding	IEA	--

OLFML2B for ontologies About GeneDecksing

Phenotypes:
2 GenomeRNAi human phenotypes for OLFML2B:

G0/1 arrest

Increased G1 DNA content

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for OLFML2B

miRNA Products:		OriGene 3'-UTR Clone: OLFML2B Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat OLFML2B
		8/15 QIAGEN miScript miRNA Assays for microRNAs that regulate OLFML2B (see all 15):
		hsa-miR-18a hsa-miR-769-5p hsa-miR-634 hsa-miR-1283 hsa-miR-449c* hsa-miR-323b-3p hsa-miR-624 hsa-miR-507

		SwitchGear 3'UTR luciferase reporter plasmid: OLFML2B 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for OLFML2B (see all 7) OriGene shRNA RFP: OLFML2B OriGene siRNA: OLFML2B
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OLFML2B
		Sirion Biotech Custom design and validation of potent shRNA sequences against OLFML2B

Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for OLFML2B
			Sirion Biotech Customized adenovirus for overexpression of OLFML2B Sirion Biotech Customized adenovirus for potent knockdown of OLFML2B

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for OLFML2B (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for OLFML2B OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: OLFML2B (NM_015441)
		Sino Biological Human cDNA Clone for OLFML2B
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for OLFML2B
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OLFML2B

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for OLFML2B
		Search LifeMap BioReagents cell lines for OLFML2B
		Sirion Biotech Customized stable knockdown cell line services for OLFML2B Sirion Biotech Customized inducible knockdown cell line services for OLFML2B Sirion Biotech Customized stable overexpressing cell line services for OLFML2B Sirion Biotech Customized inducible overexpressing cell line services for OLFML2B

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OLFML2B

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for OLFML2B

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0030198	extracellular matrix organization	IEA	--

OLFML2B for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for OLFML2B
Search CenterWatch for drugs/clinical trials and news about OLFML2B / OLM2B

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for OLFML2B gene:

NM_015441.1

Unigene Cluster for OLFML2B:

Olfactomedin-like 2B

Hs.507515 [show with all ESTs]

Unigene Representative Sequence: BC067274

6 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000533556 ENST00000294794(uc001gbt.3 uc001gbu.3 uc010pkq.2)

ENST00000525589 ENST00000367940 ENST00000367938 ENST00000451379

miRNA Products:		OriGene 3'-UTR Clone: OLFML2B Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat OLFML2B
		8/15 QIAGEN miScript miRNA Assays for microRNAs that regulate OLFML2B (see all 15):
		hsa-miR-18a hsa-miR-769-5p hsa-miR-634 hsa-miR-1283 hsa-miR-449c* hsa-miR-323b-3p hsa-miR-624 hsa-miR-507

		SwitchGear 3'UTR luciferase reporter plasmid: OLFML2B 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for OLFML2B (see all 7) OriGene shRNA RFP: OLFML2B OriGene siRNA: OLFML2B
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OLFML2B
		Sirion Biotech Custom design and validation of potent shRNA sequences against OLFML2B

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for OLFML2B (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for OLFML2B OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: OLFML2B (NM_015441)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for OLFML2B
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OLFML2B

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for OLFML2B Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat OLFML2B
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OLFML2B
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OLFML2B

Additional cDNA sequence:

AB119054.1 AK301499.1 AK316154.1 AL050137.1 BC047472.1 BC067274.1 BX648975.1

3 DOTS entries:

DT.99964182 DT.100694438 DT.87078291

24/98 AceView cDNA sequences (see all 98):

BM719150 AW137901 BC067274 BE328022 AW581166 CR600954 NM_015441 AA489716

BE645614 AA988383 AB119054 AI159936 AA427898 BU622765 AA609525 AI923256

BU626319 BE046488 BX648975 AI571800 CA449685 BQ004219 AI348665 AA235255

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

OLFML2B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCATCTTTGC

About this image

OLFML2B expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

5 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Cartilage

Lumbar Intervertebral Disc

Intervertebral Disc Nucleus Pulposus Cells

Cartilage

Pancreas

Dorsal Pancreatic Bud

Immature Beta Progenitor Cells

Pancreas

Ventral Pancreatic Bud

Immature Beta Progenitor Cells

Pancreas

Brain

Primitive Streak

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 4 LifeMap Cells

Name

Category

PureStem™ mesenchymal progenitor MEL2 (Embryonic Progenitor Cell)

Adipose, Bone, Cartilage

PureStem™ progenitor E69 (Embryonic Progenitor Cell)

PureStem™ progenitor F15 (Embryonic Progenitor Cell)

PureStem™ progenitor T36 (Embryonic Progenitor Cell)

See OLFML2B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for OLFML2B

SOURCE GeneReport for Unigene cluster: Hs.507515

SABiosciences Custom PCR Arrays for OLFML2B

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for OLFML2B Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat OLFML2B
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OLFML2B
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OLFML2B

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OLFML2B

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for OLFML2B gene from 5/15 species (see all 15) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	OLFML2B¹	olfactomedin-like 2B	71.53(n) 72.53(a)		424366 XM_422209.3 XP_422209.3
lizard (Anolis carolinensis)	Reptilia	OLFML2B⁶	--	58(a)	1 ↔ 1	4(71042561-71062810)
zebrafish (Danio rerio)	Actinopterygii	olfml2b¹	olfactomedin-like 2B	58.92(n) 56.77(a)		567907 XM_691218.4 XP_696310.4
fruit fly (Drosophila melanogaster)	Insecta	CG6867⁶	--	9(a)	1 → many	X(17917903-17922294)
worm (Caenorhabditis elegans)	Secernentea	unc-122⁶ cof-2⁶	UNCoordinated family member (unc-122) COlmedin (collagen plus olFactomedin) family membe...	15(a) 15(a)	many ↔ many many ↔ many	I(14872151-14875367) I(6250573-6252823)

ENSEMBL Gene Tree for OLFML2B (if available)
TreeFam Gene Tree for OLFML2B (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for OLFML2B gene

GLDN² OLFM3² MYOC² OLFML3² OLFML2A² OLFM2² OLFM1² OLFM4²

OLFML1²

7 SIMAP similar genes for OLFML2B using alignment to 4 protein entries: OLM2B_HUMAN (see all proteins):

FLJ00237 OLFM2 OLFM1 MYOC OLFM3 LPHN1

OLFML2A

OLFML2B for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs144220685^1,2		--	161952574(+)	`TGATTA/GAGAAC`	1	--	int¹		0	--	--	--	--
rs147764348^1,2		--	161952592(+)	`GGAAGG/TGTGGG`	1	--	int¹		0	--	--	--	--
rs186676530^1,2		--	161952607(+)	`AGGTCA/GCACTC`	1	--	int¹		0	--	--	--	--
rs191870114^1,2		--	161952677(+)	`ATGAAC/TGGGTT`	1	--	int¹		0	--	--	--	--
rs10918361^1,2	C,F,A,H	--	161952747(+)	`ACAGAA/GAAATG`	1	--	int¹		19		NA NS EA WA	1348
rs111466519^1,2		--	161952785(+)	`GAACAC/TGGGGG`	1	--	int¹		1		CSA	2
rs143582383^1,2		--	161952786(+)	`AACACA/GGGGGT`	1	--	int¹		0	--	--	--	--
rs184091712^1,2		--	161952993(+)	`TAAATG/TTCTTC`	1	--	ut3¹		0	--	--	--	--
rs1129590^1,2	C,F,A,H	--	161953015(-)	`AACGCT/CTTTTT`	1	--	ut3¹ trp³		18		NA NS EA	2006
rs186150221^1,2	C	--	161953018(+)	`AAAGCA/GTTTTT`	1	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for OLFML2B (161952982 - 161993644 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for OLFML2B
2 CNVs: 6791 4259

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing OLFML2B

DNA2.0 Custom Variant and Variant Library Synthesis for OLFML2B

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

OLFML2B for disorders About GeneDecksing

1 disease for OLFML2B: About MalaCards

atherosclerosis

Human Genome Epidemiology (HuGE) Navigator: OLFML2B (2 documents)

Export disorders for OLFML2B gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for OLFML2B gene integrated from 9 sources:
(articles sorted by number of sources associating them with OLFML2B)

Utopia: connect your pdf to the dynamic
world of online information

Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
Integrative predictive model of coronary artery calci fication in atherosclerosis. (PubMed id 19948975)¹ McGeachie M....Ramoni M.F. (2009)
Common genetic variation near the phospholamban gene is associated with cardiac repolarisation: meta-analysis of three genome-wide a ssociation studies. (PubMed id 19587794)¹ Nolte I.M....Jamshidi Y. (2009)
The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)² Bechtel S.... Schupp I. (2007)
The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)² Gregory S.G.... Bentley D.R. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)² Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)² Ota T.... Sugano S. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )² Aoki H.... Hino O. (2000)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 25903	HGNC: 24558	AceView: OLFML2B	Ensembl:ENSG00000162745	euGenes: HUgn25903
ECgene: OLFML2B	H-InvDB: OLFML2B

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for OLFML2B	Pharmacogenomics, SNPs, Pathways

Intellectual Property for OLFML2B gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for OLFML2B gene:
Search GeneIP for patents involving OLFML2B

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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	Browse OriGene Antibodies		OriGene shRNA RFP for OLFML2B
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for OLFML2B		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for OLFML2B
	OriGene Protein Over-expression Lysate for OLFML2B		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for OLFML2B		OriGene 3'-UTR Clone for OLFML2B
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for OLFML2B		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for OLFML2B
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	OriGene Custom Antibody Services for OLFML2B		OriGene Custom Protein Services for OLFML2B
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	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat OLFML2B
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing OLFML2B
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OLFML2B
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OLFML2B
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OLFML2B
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OLFML2B

	GenScript Custom Purified and Recombinant Proteins Services for OLFML2B		GenScript cDNA clones with any tag delivered in your preferred vector for OLFML2B
	GenScript Custom Assay Services for OLFML2B		GenScript Custom Superior Antibodies Services for OLFML2B
	GenScript Custom overexpressing Cell Line Services for OLFML2B		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
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	Regulatory tfbs in OLFML2B promoter
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Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
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OLFML2B Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for OLFML2B

	Gene Synthesis
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OLFML2B

	SwitchGear 3'UTR luciferase reporter plasmids for OLFML2B
	SwitchGear Promoter luciferase reporter plasmids for OLFML2B

Search ThermoFisher Antibodies for OLFML2B

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OLFML2B

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for OLFML2B

Sirion Biotech Customized:

	stable knockdown cell line services for OLFML2B
	inducible knockdown cell line services for OLFML2B
	design and validation of potent shRNA sequences against OLFML2B
	adenovirus for potent knockdown of OLFML2B
	adenovirus for overexpression of OLFML2B
	stable overexpressing cell line services for OLFML2B
	inducible overexpressing cell line services for OLFML2B

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 13 May 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes OLFML2B gene at Home site.

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OLFML2B Gene

olfactomedin-like 2B

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OLFML2B Gene

olfactomedin-like 2B

Aliasesfor OLFML2B gene

Summariesfor OLFML2B gene

Genomic Viewsfor OLFML2B gene

Proteinsfor OLFML2B gene

Protein Domains /Familiesfor OLFML2B gene

Functionfor OLFML2B gene

Pathways & Interactionsfor OLFML2B gene

Drugs & Compoundsfor OLFML2B gene

Transcriptsfor OLFML2B gene

Expression for OLFML2B gene

Orthologsfor OLFML2B gene

Paralogsfor OLFML2B gene

Genomic Variantsfor OLFML2B gene

Disorders / Diseasesfor OLFML2B gene

Publicationsfor OLFML2B gene

External Searches for OLFML2B gene

Genome Databases showing OLFML2B gene

Other Databases showing OLFML2B gene

Specialized Databases showing OLFML2B gene

Intellectual Propertyfor OLFML2B gene

Productsfor OLFML2B gene

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Aliases
for OLFML2B gene

Summaries
for OLFML2B gene

Genomic Views
for OLFML2B gene

Proteins
for OLFML2B gene

Protein Domains /
Families
for OLFML2B gene

Function
for OLFML2B gene

Pathways & Interactions
for OLFML2B gene

Drugs & Compounds
for OLFML2B gene

Transcripts
for OLFML2B gene

Expression
for OLFML2B gene

Orthologs
for OLFML2B gene

Paralogs
for OLFML2B gene

Genomic Variants
for OLFML2B gene

Disorders / Diseases
for OLFML2B gene

Publications
for OLFML2B gene

Intellectual Property
for OLFML2B gene

Products
for OLFML2B gene