Aliases for OLFM4 Gene
External Ids for OLFM4 Gene
This gene was originally cloned from human myeloblasts and found to be selectively expressed in inflammed colonic epithelium. This gene encodes a member of the olfactomedin family. The encoded protein is an antiapoptotic factor that promotes tumor growth and is an extracellular matrix glycoprotein that facilitates cell adhesion. [provided by RefSeq, Mar 2011]
GeneCards Summary for OLFM4 Gene
OLFM4 (Olfactomedin 4) is a Protein Coding gene. An important paralog of this gene is GLDN.
UniProtKB/Swiss-Prot for OLFM4 Gene
May promote proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. In myeloid leukemic cell lines, inhibits cell growth and induces cell differentiation and apoptosis. May play a role in the inhibition of EIF4EBP1 phosphorylation/deactivation. Facilitates cell adhesion, most probably through interaction with cell surface lectins and cadherin.