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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

OLFM1 Gene

protein-coding   GIFtS: 56
GCID: GC09P137967

olfactomedin 1
 Explore 7 diseases affiliated with
OLFM1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for OLFM1    

Aliases
for OLFM1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Olfactomedin 11 2     Neuroblastoma Protein2
NOE11 2 3     Noelin1
AMY1 2 5     Olfactomedin Related ER Localized Protein2
OlfA1 2     Olfactomedin-13
Neuronal Olfactomedin-Related ER Localized Protein2 3     Pancortin 12
NOELIN1     NOEL13
NOELIN12     Olfactomedin-13

External Ids:    HGNC: 171871   Entrez Gene: 104392   Ensembl: ENSG000001305587   OMIM: 6053665   UniProtKB: Q997843   

Export aliases for OLFM1 gene to outside databases

Previous GC identifers: GC09P129117 GC09P129736 GC09P131490 GC09P133406 GC09P135193 GC09P137106 GC09P107430


Summaries
for OLFM1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for OLFM1:
This gene product shares extensive sequence similarity with the rat neuronal olfactomedin-related ER localized protein.
While the exact function of the encoded protein is not known, its abundant expression in brain suggests that it may
have an essential role in nerve tissue. Several alternatively spliced transcripts encoding different isoforms have
been found for this gene. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: NOE1_HUMAN, Q99784
Function: May play an important role in regulating the production of neural crest cells by the neural tube (By
similarity)

Gene Wiki entry for OLFM1


Genomic Views
for OLFM1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000009.11  NC_018920.1  NT_019501.13  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the OLFM1 gene promoter:
         NRSF form 1   NRSF form 2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: OLFM1 promoter sequence
   Search SABiosciences Chromatin IP Primers for OLFM1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OLFM1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q34.3   Ensembl cytogenetic band:  9q34.3   HGNC cytogenetic band: 9q34.3

OLFM1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
OLFM1 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09P137967:  view genomic region     (about GC identifiers)

Start:
 137,967,089 bp from pter      End:
 138,013,030 bp from pter
Size:
 45,942 bases      Orientation:
 plus strand

Proteins
for OLFM1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: NOE1_HUMAN, Q99784 (See protein sequence)
Recommended Name: Noelin precursor  
Size: 485 amino acids; 55343 Da
Subunit: Peripherally associated with AMPAR complex. AMPAR complex consists of an inner core made of 4 pore-forming
GluA/GRIA proteins (GRIA1, GRIA2, GRIA3 and GRIA4) and 4 major auxiliary subunits arranged in a twofold symmetry. One
of the two pairs of distinct binding sites is occupied either by CNIH2, CNIH3 or CACNG2, CACNG3. The other harbors
CACNG2, CACNG3, CACNG4, CACNG8 or GSG1L. This inner core of AMPAR complex is complemented by outer core constituents
binding directly to the GluA/GRIA proteins at sites distinct from the interaction sites of the inner core
constituents. Outer core constituents include at least PRRT1, PRRT2, CKAMP44/SHISA9, FRRS1L and NRN1. The proteins of
the inner and outer core serve as a platform for other, more peripherally associated AMPAR constituents, including
OLFM1. Alone or in combination, these auxiliary subunits control the gating and pharmacology of the AMPAR complex and
profoundly impact their biogenesis and protein processing (By similarity)
Subcellular location: Secreted (Potential). Cell junction, synapse (By similarity)
Secondary accessions: Q53XZ8 Q6IMJ4 Q969S7 Q99452
Alternative splicing: 4 isoforms:  Q99784-1   Q99784-2   Q99784-3   Q99784-4   

Explore the universe of human proteins at neXtProt for OLFM1: NX_Q99784

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q99784

    • OLFM1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_006325.1  NP_055094.1  

    ENSEMBL proteins: 
     ENSP00000360864   ENSP00000277415   ENSP00000252854   ENSP00000360866   ENSP00000340318  
     ENSP00000360861   ENSP00000444296   ENSP00000376717   ENSP00000360858   ENSP00000443806  
     ENSP00000437906  

    Human Recombinant Protein Products: 
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    Novus Biologicals OLFM1 Protein
    Novus Biologicals OLFM1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for OLFM1

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005615extracellular space IEA--
    GO:0005788endoplasmic reticulum lumen ----
    GO:0030054cell junction IEA--
    GO:0045202synapse IEA--


    OLFM1 for ontologies           About GeneDecksing



    OLFM1 Antibody Products: 
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    Uscn ELISAs and CLIAs for OLFM1

    Protein Domains /
    Families
    for OLFM1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    OLFM1 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR022082 Noelin-1
     IPR003112 Olfac-like
     IPR011047 Quinonprotein_ADH-like_supfam

    Graphical View of Domain Structure for InterPro Entry Q99784

    ProtoNet protein and cluster: Q99784

    1 Blocks protein family: IPB003112 Olfactomedin-like

    UniProtKB/Swiss-Prot: NOE1_HUMAN, Q99784
    Similarity: Contains 1 olfactomedin-like domain


    Function
    for OLFM1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: NOE1_HUMAN, Q99784
    Function: May play an important role in regulating the production of neural crest cells by the neural tube (By
    similarity)

    miRNA
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    hsa-miR-4317 hsa-miR-132 hsa-miR-103a hsa-miR-223 hsa-miR-3122 hsa-miR-3613-3p hsa-miR-212 hsa-miR-33b
    SwitchGear 3'UTR luciferase reporter plasmid: OLFM1 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OLFM1 

    Cell Line
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    Search LifeMap BioReagents cell lines for OLFM1

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OLFM1

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI17043677


    OLFM1 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for OLFM1:
     Decreased POU5F1-GFP protein e 

    Animal Models:
         Mouse knock-out Olfm1tm1.1Lex for OLFM1
         4 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Olfm1):
     homeostasis/metabolism  nervous system  no phenotypic analysis  reproductive system 

    OLFM1 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for OLFM1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for OLFM1

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    5 Interacting proteins for OLFM1 (Q997841, 3 ENSP000002528544) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DISC1Q9NRI51, 3, ENSP000003555964EBI-1105073,EBI-529989 I2D: score=2 STRING: ENSP00000355596
    TRAF3IP1Q8TDR03, ENSP000003624244I2D: score=1 STRING: ENSP00000362424
    EGFRP005333, ENSP000002754934I2D: score=2 STRING: ENSP00000275493
    YWHABP319463I2D: score=1 
    --ENSP000003936424STRING: ENSP00000393642
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007399nervous system development TAS9039501
    GO:0051259protein oligomerization IEA--


    OLFM1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for OLFM1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for OLFM1
    Search CenterWatch for drugs/clinical trials and news about OLFM1 / NOE1 

    Transcripts
    for OLFM1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for OLFM1 gene (3 alternative transcripts): 
    NM_006334.3  NM_058199.2  NM_014279.4  

    Unigene Cluster for OLFM1:

    Olfactomedin 1
    Hs.522484  [show with all ESTs]
    Unigene Representative Sequence: NM_014279
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000371799(uc010naq.2) ENST00000277415(uc004cfk.4) ENST00000252854(uc004cfl.4)
    ENST00000371801 ENST00000339720 ENST00000371796(uc010nar.3) ENST00000539529
    ENST00000392991 ENST00000371793 ENST00000539877 ENST00000545657 ENST00000483042(uc004cfn.4)


    miRNA
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    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat OLFM1
    8/16 QIAGEN miScript miRNA Assays for microRNAs that regulate OLFM1 (see all 16):
    hsa-miR-4317 hsa-miR-132 hsa-miR-103a hsa-miR-223 hsa-miR-3122 hsa-miR-3613-3p hsa-miR-212 hsa-miR-33b
    SwitchGear 3'UTR luciferase reporter plasmid: OLFM1 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for OLFM1 (see all 7)
    OriGene shRNA RFP: OLFM1
    OriGene siRNA: OLFM1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OLFM1
    Clone
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    GenScript: all cDNA clones in your preferred vector (see all 2): OLFM1 (NM_014279)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for OLFM1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OLFM1 
    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OLFM1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OLFM1

    Additional cDNA sequence: 

    AF035301.1 AK090818.1 AK096304.1 AK289719.1 AK289921.1 AK290478.1 BC000189.1 BC008763.2 
    BC011741.2 BC015437.2 BT007146.1 D82343.1 U79299.1 

    13 DOTS entries:

    DT.449449  DT.100755444  DT.100027832  DT.95293576  DT.92430258  DT.99982681  DT.40109076  DT.95293570 
    DT.95293568  DT.102826070  DT.121165746  DT.95129327  DT.95293574 

    24/375 AceView cDNA sequences (see all 375):

    BT007146 F10444 F09914 F05512 BM709641 CA391735 AI571275 F06276 
    BM709177 F08750 BQ002292 F04056 NM_058199 F08313 F03386 BQ717710 
    F05034 BQ889241 AA364901 F08900 F09158 AK090818 AF035301 F02071 

    GeneLoc Exon Structure

    5/11 Alternative Splicing Database (ASD) splice patterns (SP) for OLFM1 (see all 11)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b ^ 11a · 11b · 11c · 11d ^ 12a · 12b ^ 13
    SP1:                                                              -     -     -                             -     -                             -               
    SP2:                                      -     -     -     -     -     -     -                             -     -                             -               
    SP3:                                                        -     -     -     -                             -     -                                             
    SP4:                                                                          -                             -     -                                             
    SP5:                                                                                                                                                            


    ECgene alternative splicing isoforms for OLFM1

    Expression
    for OLFM1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    OLFM1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TAACCTTAAG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    OLFM1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    CyT49 (Embryonic Stem Cell)Early Embryo, Inner Cell Mass
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See OLFM1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for OLFM1

    SOURCE GeneReport for Unigene cluster: Hs.522484
        SABiosciences Custom PCR Arrays for OLFM1
    Primer
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OLFM1

    Orthologs
    for OLFM1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for OLFM1 gene from 6/15 species (see all 15)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves OLFM11 olfactomedin 1 86.65(n)
    95.88(a)    		   395535  NM_204767.1  NP_990098.1 
    lizard
    (Anolis carolinensis)    		 Reptilia OLFM16
    		 --
    		 93(a)
    		 1 ↔ 1
    		 GL343956.1(86251-105786)
    African clawed frog
    (Xenopus laevis)    		 Amphibia LOC3982872 noelin-1 81.18(n)    AF416482.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii olfm1a6
    		 olfactomedin 1a
    		 76(a)
    		 1 ↔ 1
    		 5(68309372-68353093)
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG68676
    		 --
    		 8(a)
    		 1 → many
    		 X(17917903-17922294)
    worm
    (Caenorhabditis elegans)    		 Secernentea unc-1226
    cof-26
    		 UNCoordinated family member (unc-122)
    COlmedin (collagen plus olFactomedin) family membe...
    		 14(a)
    13(a)
    		 many ↔ many
    many ↔ many
    		 I(14872151-14875367)
    I(6250573-6252823)


    ENSEMBL Gene Tree for OLFM1 (if available)
    TreeFam Gene Tree for OLFM1 (if available) 

    Paralogs
    for OLFM1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for OLFM1 gene
    GLDN2  OLFM32  OLFML2B2  MYOC2  OLFML32  OLFML2A2  OLFM22  OLFML12  
    OLFM42  
    12 SIMAP similar genes for OLFM1 using alignment to 12 protein entries:     NOE1_HUMAN (see all proteins):
    OLFM3    OLFM2    MYOC    LPHN2    GLDN    OLFML2B
    FLJ00237    LPHN3    OLFML2A    LPHN1    DKFZp686H1812    OLFML1

    OLFM1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for OLFM1
    PGOHUM00000234154


    Genomic Variants
    for OLFM1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1132 NCBI SNPs in OLFM1 are shown (see all 1132)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 9 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs2021864311,2
    		C--107456090(+) TAAATA/GATTGA 1 -- int10--------
    rs1119040981,2
    		C,F,--107474175(+) AGTACT/CCACTG 1 -- int11Minor allele frequency- C:0.03NA 120
    rs615912741,2
    		C,F,--137965112(+) TCACAG/TGTCTC 2 -- us2k110Minor allele frequency- T:0.39NA WA CSA EA 371
    rs133008561,2
    		C,F,H,--137965157(+) GCATCA/GATGTG 2 -- us2k19Minor allele frequency- G:0.07NS EA NA 662
    rs794337391,2
    		F,--137965187(+) GGGTCG/AAGGCC 2 -- us2k11Minor allele frequency- A:0.03WA 118
    rs1507324471,2
    		--137965203(+) TGCTGA/CGCGTG 2 -- us2k10--------
    rs1390966401,2
    		--137965313(+) CCATTC/TGACAG 2 -- us2k10--------
    rs1142361191,2
    		C,F,--137965314(+) CATTCG/AACAGA 2 -- us2k11Minor allele frequency- A:0.03WA 118
    rs1820578331,2
    		--137965340(+) TCAGAC/TAGCCA 2 -- us2k10--------
    rs93082811,2
    		C,F,A,H,--137965410(+) CTCAAC/TGATCC 2 -- us2k123Minor allele frequency- T:0.45NS EA NA WA CSA 2351

    HapMap Linkage Disequilibrium report for OLFM1 (137967089 - 138013030 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 10 variations for OLFM1
         1 CNV: 70824
         9 Indels: 47667 83215 96338 83217 83216 83214 96337 83218 96336

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    Disorders / Diseases
    for OLFM1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OLFM1 for disorders           About GeneDecksing

    OMIM gene information: 605366    OMIM disorders: --

    7 diseases for OLFM1:    About MalaCards
    neuronitis    neuroblastoma    spindle cell sarcoma    spontaneous abortion
    pericarditis    sarcoma    schizophrenia

    Human Genome Epidemiology (HuGE) Navigator: OLFM1 (1 document)

    Export disorders for OLFM1 gene to outside databases

    Publications
    for OLFM1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for OLFM1 gene, integrated from 9 sources (see all 23):
    (articles sorted by number of sources associating them with OLFM1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and cloning of neuroblastoma-specific and nerve tissue-specific genes through compiled expression profiles. (PubMed id 9039501)1, 2, 3 Yokoyama M.... Matsubara K. (1996)
    2. Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. (PubMed id 16335952)1, 2 Liu T.... Smith R.D. (2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. Large-scale concatenation cDNA sequencing. (PubMed id 9110174)1, 2 Yu W.... Gibbs R.A. (1997)
    6. Bioinformatic approaches for identification and characterization of olfactomedin related genes with a potential role in pathogenesis of ocular disorders. (PubMed id 15123989)2, 9 Mukhopadhyay A.... Ray K. (2004)
    7. Wnt activation downregulates olfactomedin-1 in Fallopi an tubal epithelial cells: a microenvironment predisposed to tubal ectopic pregn ancy. (PubMed id 21968811)1 Kodithuwakku S.P....Lee K.F. (2012)
    8. Serum ferritin levels are associated with a distinct p henotype of chronic hepatitis C poorly responding to pegylated interferon-alpha and ribavirin therapy. (PubMed id 22095909)1 Lange C.M....Bochud P.Y. (2012)
    9. Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
    10. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)

    External Searches for OLFM1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Aliases
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    Genome Databases showing OLFM1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10439 HGNC: 17187 AceView: OLFM1 Ensembl:ENSG00000130558 euGenes: HUgn10439
    ECgene: OLFM1 H-InvDB: OLFM1

    Other Databases showing OLFM1 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing OLFM1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for OLFM1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for OLFM1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for OLFM1 gene:
    Search GeneIP for patents involving OLFM1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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