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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

OLA1 Gene

protein-coding   GIFtS: 54
GCID: GC02M174937

Obg-like ATPase 1

(Previous name: GTP-binding protein 9 (putative) )
(Previous symbol: GTPBP9)
 Explore 6 diseases affiliated with
OLA1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for OLA1    

Aliases
for OLA1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Obg-Like ATPase 11 2     DNA Damage-Regulated Overexpressed In Cancer 45 Protein2
GTPBP91 2 3     GTP-Binding Protein PTD0042
GTP-Binding Protein 9 (Putative)1 2     Homologous Yeast-44.2 Protein2
DOC452 3     DNA Damage-Regulated Overexpressed In Cancer 453
PTD0041     GTP-Binding Protein 93
GBP452     EC 3.6.38
GTBP92     

External Ids:    HGNC: 288331   Entrez Gene: 297892   Ensembl: ENSG000001384307   OMIM: 6111755   UniProtKB: Q9NTK53   

Export aliases for OLA1 gene to outside databases

Previous GC identifers: GC02M174646 GC02M166816


Summaries
for OLA1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: OLA1_HUMAN, Q9NTK5
Function: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP

Gene Wiki entry for OLA1


Genomic Views
for OLA1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.1  NT_005403.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the OLA1 gene promoter:
         TBP   USF1   HNF-4alpha2   Tal-1beta   HNF-4alpha1   AREB6   S8   USF-1   COMP1   ITF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: OLA1 promoter sequence
   Search SABiosciences Chromatin IP Primers for OLA1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OLA1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q31.1   Ensembl cytogenetic band:  2q31.1   HGNC cytogenetic band: 2q31.1

OLA1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
OLA1 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M174937:  view genomic region     (about GC identifiers)

Start:
 174,937,175 bp from pter      End:
 175,113,426 bp from pter
Size:
 176,252 bases      Orientation:
 minus strand

Proteins
for OLA1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: OLA1_HUMAN, Q9NTK5 (See protein sequence)
Recommended Name: Obg-like ATPase 1  
Size: 396 amino acids; 44744 Da
Subunit: Monomer
Subcellular location: Cytoplasm. Nucleus. Nucleus, nucleolus. Note=Predominantly cytoplasmic, shuttles between the
nucleus and the cytoplasm
1 PDB 3D structure from and Proteopedia for OLA1:
2OHF (3D)    
Secondary accessions: D7EHM2 Q5BJD7 Q8NCI8 Q96CU1 Q96SV2 Q9P1D3 Q9UNY9 Q9Y6G4
Alternative splicing: 3 isoforms:  Q9NTK5-1   Q9NTK5-2   Q9NTK5-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for OLA1: NX_Q9NTK5

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9NTK5

    • 4/17 DME Specific Peptides for OLA1 (Q9NTK5) (see all 17)
     LEKVAVR  DPGALVIP  DFKEEGSE  ACDGIFHL 

    OLA1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001011708.1  NP_037473.3  

    ENSEMBL proteins: 
     ENSP00000284719   ENSP00000340167   ENSP00000410385   ENSP00000386350   ENSP00000404864  
     ENSP00000414568  

    Human Recombinant Protein Products: 
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    Novus Biologicals OLA1 Proteins
    Novus Biologicals OLA1 Lysate
    Browse Sino Biological Recombinant Proteins
    ProSpec Recombinant Protein for OLA1
    Uscn Proteins for OLA1

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005730nucleolus IEA--
    GO:0005737cytoplasm IDA--


    OLA1 for ontologies           About GeneDecksing



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    Uscn Antibodies for OLA1
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    Uscn ELISAs and CLIAs for OLA1

    Protein Domains /
    Families
    for OLA1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    OLA1 for domains           About GeneDecksing

    5/6 InterPro domains/families (see all 6):
     IPR012675 Beta-grasp_dom
     IPR013029 DUF933
     IPR004396 CHP00092
     IPR012676 TGS-like
     IPR006073 GTP_binding_domain

    Graphical View of Domain Structure for InterPro Entry Q9NTK5

    ProtoNet protein and cluster: Q9NTK5

    3 Blocks protein families:
    IPB002917 GTP-binding protein
    IPB006073 GTP1/OBG GTP-binding protein family signature
    IPB013029 Protein of unknown function DUF933


    UniProtKB/Swiss-Prot: OLA1_HUMAN, Q9NTK5
    Similarity: Belongs to the GTP1/OBG family. YchF/OLA1 subfamily
    Similarity: Contains 1 G (guanine nucleotide-binding) domain


    Function
    for OLA1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: OLA1_HUMAN, Q9NTK5
    Function: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP
    Induction: Strongly down-regulated by DNA damage-inducing agents

    Enzyme Number (IUBMB): EC 3.6.32

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat OLA1
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    hsa-miR-26a-2* hsa-miR-3607-3p hsa-miR-218-1* hsa-miR-605 hsa-miR-485-3p hsa-miR-376a* hsa-miR-3613-3p hsa-miR-29a*
    SwitchGear 3'UTR luciferase reporter plasmid: OLA1 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for OLA1 (see all 4)
    OriGene shRNA RFP: OLA1
    OriGene siRNA: OLA1
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    Gene Editing
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    Clone
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OLA1 

    Cell Line
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    Search LifeMap BioReagents cell lines for OLA1

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OLA1

    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
    GO:0005524ATP binding IDA17430889
    GO:0005525GTP binding IEA--
    GO:0016787hydrolase activity IEA--


    OLA1 for ontologies           About GeneDecksing



    Pathways & Interactions
    for OLA1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for OLA1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/725 Interacting proteins for OLA1 (Q9NTK51, 2, 3 ENSP000002847194) via UniProtKB, MINT, STRING, and/or I2D (see all 725)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=1 
    HIST1H4BP628053I2D: score=1 
    HIST1H4CP628053I2D: score=1 
    HIST1H4DP628053I2D: score=1 
    HIST1H4EP628053I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006200ATP catabolic process IDA17430889


    OLA1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for OLA1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for OLA1

    1 HMDB Compound for OLA1    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--
    Search CenterWatch for drugs/clinical trials and news about OLA1 

    Transcripts
    for OLA1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for OLA1 gene (2 alternative transcripts): 
    NM_001011708.1  NM_013341.3  

    Unigene Cluster for OLA1:

    Obg-like ATPase 1
    Hs.157351  [show with all ESTs]
    Unigene Representative Sequence: NM_013341
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000284719(uc002uih.3 uc002uii.3 uc010fqq.3 uc010fqr.3)
    ENST00000344357 ENST00000428402 ENST00000497760 ENST00000409546 ENST00000392560
    ENST00000462000 ENST00000429575 ENST00000427472

    miRNA
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    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat OLA1
    8/98 QIAGEN miScript miRNA Assays for microRNAs that regulate OLA1 (see all 98):
    hsa-miR-26a-2* hsa-miR-3607-3p hsa-miR-218-1* hsa-miR-605 hsa-miR-485-3p hsa-miR-376a* hsa-miR-3613-3p hsa-miR-29a*
    SwitchGear 3'UTR luciferase reporter plasmid: OLA1 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for OLA1 (see all 4)
    OriGene shRNA RFP: OLA1
    OriGene siRNA: OLA1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OLA1
    Clone
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    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for OLA1 (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: OLA1 (NM_016937)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OLA1 
    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OLA1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OLA1

    Additional cDNA sequence: 

    AF078859.1 AF078868.1 AF090946.1 AF134478.1 AK027523.1 AK074710.1 AK225112.1 AK225138.1 
    AK296339.1 AL136546.1 AL833441.1 BC012842.1 BC013925.1 BC029376.1 BC068447.1 BC091522.1 
    DQ250006.1 

    24/29 DOTS entries (see all 29):

    DT.75123637  DT.100880350  DT.100692069  DT.91777312  DT.120967622  DT.100766712  DT.91777295  DT.100880343 
    DT.100880345  DT.95368241  DT.100663964  DT.100880347  DT.120967581  DT.100880341  DT.100880351  DT.100880352 
    DT.102834815  DT.120667025  DT.120967580  DT.120967585  DT.120967657  DT.120967666  DT.120967676  DT.91777309 

    24/540 AceView cDNA sequences (see all 540):

    BC012842 AU280244 BU171221 AA233500 CB118916 BX409503 BG501274 BG183323 
    BQ233033 BQ425195 AA761981 AL557475 CR594307 BU193440 BU838498 BX419580 
    AA300711 AA608631 CB151941 BU153539 BE349861 AK074710 AL516522 CR607845 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for OLA1 (see all 9)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12a · 12b · 12c ^ 13a · 13b ^ 14
    SP1:                                                                    -     -                                                     -                     
    SP2:                                -                                   -     -                                                                           
    SP3:                                -     -                                   -                                                                           
    SP4:                                -     -                             -     -                                                                           
    SP5:                                -     -                             -     -           -     -     -                                                   


    ECgene alternative splicing isoforms for OLA1

    Expression
    for OLA1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    OLA1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TTTTACAGTA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image
    See OLA1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for OLA1

    SOURCE GeneReport for Unigene cluster: Hs.157351

    UniProtKB/Swiss-Prot: OLA1_HUMAN, Q9NTK5
    Tissue specificity: Expressed in all tissues tested but its expression is more abundant in testis, liver, lung, and
    brain. Overexpressed in several malignancies, including cancers of the colon, rectum, ovary, lung, stomach, and uterus

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    In Situ
    Assay Products:     
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    Orthologs
    for OLA1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the last universal common ancestor (LUCA).

    Orthologs for OLA1 gene from 11/46 species (see all 46)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Ola11 , 5 Obg-like ATPase 11, 5 93.43(n)1
    99.49(a)1    		   2 (43.35 cM)5
    670591  NM_025942.21  NP_080218.11 
     730928015 
    chicken
    (Gallus gallus)    		 Aves OLA11 Obg-like ATPase 1 86.2(n)
    91.16(a)    		   424144  NM_001031254.1  NP_001026425.1 
    lizard
    (Anolis carolinensis)    		 Reptilia OLA16
    		 --
    		 91(a)
    		 1 ↔ 1
    		 GL343316.1(169773-346294)
    African clawed frog
    (Xenopus laevis)    		 Amphibia MGC540332 hypothetical protein MGC54033 82.71(n)    BC046937.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii wufc66b092 Danio rerio cDNA clone MGC55768 IMAGE3816932, complete more 77.41(n)    BC051155.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG13541 CG1354 64.68(n)
    74.35(a)    		   31914  NM_132352.3  NP_572580.1 
    worm
    (Caenorhabditis elegans)    		 Secernentea tag-2101 Protein TAG-210 63.27(n)
    68.19(a)    		   173205  NM_060948.2  NP_493349.1 
    baker's yeast
    (Saccharomyces cerevisiae)    		 Saccharomycetes OLA1(YBR025C)4
    OLA11    		 P-loop ATPase with similarity to human OLA1 and bacterial more4
    Ola1p1    		 58.64(n)1
    55.24(a)1    		   2(291865-290681)4
    8523131, 4  NP_009581.11, 4 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT1G305801 GTP-binding protein 62.33(n)
    62.5(a)    		   839938  NM_102795.2  NP_174346.1 
    rice
    (Oryza sativa)    		 Liliopsida Os.96342 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 75.41(n)    AK062256.1 


    ENSEMBL Gene Tree for OLA1 (if available)
    TreeFam Gene Tree for OLA1 (if available) 

    Paralogs
    for OLA1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for OLA1 gene
    1 SIMAP similar gene for OLA1 using alignment to 4 protein entries:     OLA1_HUMAN (see all proteins):
    PTD004

    OLA1 for paralogs           About GeneDecksing


    5/6 Pseudogenes.org Pseudogenes for OLA1 (see all 6)
    PGOHUM00000239473 PGOHUM00000239474 PGOHUM00000237296 PGOHUM00000237297 PGOHUM00000246342


    Genomic Variants
    for OLA1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2670 NCBI SNPs in OLA1 are shown (see all 2670)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 2 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1432648451,2
    		--174936684(+) TACAGA/GCGAGG 2 -- ds50010--------
    rs1878074311,2
    		--174936732(+) AGGTCA/GTACAA 2 -- ds50010--------
    rs1467067711,2
    		--174936780(+) CTGACC/TCCTGA 2 -- ds50010--------
    rs124667881,2
    		C,F,A,H,--174936851(+) ACTTGC/TCATTC 2 -- ds500114Minor allele frequency- T:0.31NS EA NA WA CSA 781
    rs575879081,2
    		F,--174936880(+) CTTAGA/GTGTTT 2 -- ds50011Minor allele frequency- G:0.03WA 118
    rs133931801,2
    		C,F,--174936894(+) AAGTGT/CTATAA 2 -- ds50015Minor allele frequency- C:0.15WA CSA NA 243
    rs1400498721,2
    		--174936907(+) CGGCAC/TTGCTG 2 -- ds50010--------
    rs1144319871,2
    		F,--174936989(+) GAAGCG/CCTTGC 2 -- ds50011Minor allele frequency- C:0.02WA 118
    rs1915591831,2
    		--174937012(+) CACGTG/TAGTCC 2 -- ds50010--------
    rs1836848561,2
    		--174937079(+) AGTGGC/TTTGGG 2 -- ds50010--------

    HapMap Linkage Disequilibrium report for OLA1 (174937175 - 175113426 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for OLA1
         2 Indels: 42761 61860

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    Disorders / Diseases
    for OLA1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OLA1 for disorders           About GeneDecksing

    OMIM gene information: 611175    OMIM disorders: --

    6 diseases for OLA1:    About MalaCards
    down syndrome    breast cancer    pneumonia    tuberculosis
    malaria    mycobacterium tuberculosis

    Human Genome Epidemiology (HuGE) Navigator: OLA1 (1 document)

    Export disorders for OLA1 gene to outside databases

    Publications
    for OLA1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for OLA1 gene, integrated from 9 sources (see all 28):
    (articles sorted by number of sources associating them with OLA1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Human OLA1 defines an ATPase subfamily in the Obg family of GTP- binding proteins. (PubMed id 17430889)1, 2, 3 Koller-Eichhorn R.... Kambach C. (2007)
    2. DOC45, a novel DNA damage-regulated nucleocytoplasmic ATPase that is overexpressed in multiple human malignancies. (PubMed id 20053727)1, 2 Sun H....Huang Y. (2010)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
    6. Targeted ubiquitination and degradation of G-protein-c oupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complex. (PubMed id 22952844)1 Wu Z....Ma L. (2012)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    8. Global landscape of HIV-human protein complexes. (PubMed id 22190034)1 Jager S....Krogan N.J. (2012)
    9. A cohesin-RAD21 interactome. (PubMed id 22145905)1 Panigrahi A.K....Pati D. (2012)
    10. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)

    External Searches for OLA1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
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    Genome Databases showing OLA1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 29789 HGNC: 28833 AceView: PTD004 Ensembl:ENSG00000138430 euGenes: HUgn29789
    ECgene: OLA1 H-InvDB: OLA1

    Other Databases showing OLA1 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing OLA1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for OLA1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for OLA1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for OLA1 gene:
    Search GeneIP for patents involving OLA1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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