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Aliases & Descriptions for OLA1
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc
, and/or 7 Ensembl ,
8 miRBase )About This Section
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Aliases DKFZp313H1942 2 EC 3.6.3.- 3 GTPBP9 2 , 3 OTTHUMP00000163173 2 PTD004 1 , 2
Descriptions GTP-binding protein 9 3 GTP-binding protein 9 (putative) 1 , 2 GTP-binding protein PTD004 2 Obg-like ATPase 1 2 homologous yeast-44.2 protein 2
Search outside databases for aliases for OLA1 gene
Summaries for OLA1 (According to Entrez Gene ,
Wikipedia's
Gene Wiki ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
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UniProtKB/Swiss-Prot: OLA1_HUMAN, Q9NTK5 Function : Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity forGTP
Gene Wiki entry for OLA1
Genomic Location for OLA1
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 36) ,
and/or miRBase ,
Genomic Views according to
UCSC and
Ensembl ,
Transcription factor binding sites according to
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Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 2q31.1 Ensembl cytogenetic band: 2q31.1 HGNC cytogenetic band: 2q31.1 OLA1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc gene densities for chromosome 2 GeneLoc Exon Structure
GeneLoc location for GC02M174646:
(about GC identifiers )
Start:
174,645,421 bp from pter
End:
174,821,611 bp from pter
Size:
176,191 bases
Orientation:
minus strand
RefSeq DNA sequence: NC_000002.10 NT_005403.16 Proteins for OLA1
(According to
1 UniProtKB ,
and/or Ensembl ,
Phosphorylation sites according to 2 Phosphosite ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Enzo Life Sciences ,
Abnova ,
OriGene and/or,
Abcam ,
Biochemical Assays by
Invitrogen ,
Millipore ,
R&D Systems ,
Cell Signaling Technology , and/or
Enzo Life Sciences ,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene ,
Antibodies by Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Cell Signaling Technology ,
Abcam ,
Abnova , and/or
Novus Biologicals )
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UniProtKB/Swiss-Prot: OLA1_HUMAN, Q9NTK5 (See
protein sequence )Recommended Name: Obg-like ATPase 1 Size : 396 amino acids; 44744 Da
Subunit : Monomer
PDB structures from and Proteopedia : 2OHF (3D)
 
Secondary accessions : Q5BJD7 Q8NCI8 Q96CU1 Q96SV2 Q9P1D3 Q9UNY9 Q9Y6G4Alternative splicing : 3 isoforms : Q9NTK5-1 Q9NTK5-2 Q9NTK5-3
REFSEQ proteins (2 alternative transcripts):
NP_001011708.1 NP_037473.3 ENSEMBL proteins: ENSP00000340167 ENSP00000386350 ENSP00000284719 ENSP00000376343 Human Recombinant Proteins               OriGene Purified Recombinant Human Protein: OLA1 2 Gene Ontology (GO) cellular component terms (links to tree view) :
About this table Antibodies for OLA1: Assays for OLA1:
Protein
Domains/ Families for OLA1(According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
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Graphical View of Domain Structure for InterPro Entry Q9NTK5 ProtoNet protein and cluster: Q9NTK5
3 Blocks protein families : IPB002917 GTP-binding protein IPB006073 GTP1/OBG GTP-binding protein family signature IPB013029 Protein of unknown function DUF933 UniProtKB/Swiss-Prot: OLA1_HUMAN, Q9NTK5 Similarity : Belongs to the GTP1/OBG family
Gene Function for OLA1
(According to MGI Jun 06 2009, UniProtKB ,
IUBMB ,and/or Genatlas ,
shRNA from
OriGene ,
Sigma-Aldrich , RNAi from
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RNAi Products ,
Clones , and
Q-PCR Products
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OriGene , and/or
Abnova ,
siRNAs from
Applied Biosystems ,
SYBR primers from OriGene ,
Cell-based Assays from Millipore ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
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               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2 ): NM_001011708 Applied Biosystems Silencer ® siRNAs for OLA1 Sigma-Aldrich siRNA for OLA1 Sigma-Aldrich shRNA for OLA1 Explore Sigma-Aldrich super-pooled esiRNAs                OriGene GFP tagged cDNA clones in CMV expression vector (see all 2 ): NM_001011708                                  Myc/DDK tagged cDNA clones in CMV expression vector (see all 2 ): NM_001011708                                  untagged cDNA clones in CMV expression vector (see all 3 ): NM_001011708  Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_013341 UniProtKB/Swiss-Prot: OLA1_HUMAN, Q9NTK5 Function : Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity forGTP Catalytic activity : ATP + H2O = ADP + phosphateEnzyme Number (IUBMB): EC 3.6.3.-
5 Gene Ontology (GO) molecular function terms (links to tree view) :
About this table
Pathways & Interactions for OLA1
(Pathways according to Invitrogen
(maps by GeneGo ),
Millipore ,
Cell Signaling Technology ,
Sigma-Aldrich ,
KEGG
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Proteins Network according to
SABiosciences ,
Interactions according to 1 UniProtKB ,
2 MINT , and/or
3 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
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5 Interacting proteins for OLA1 (ENSP00000284719 3 Q9NTK5 1 , 2 ) via UniProtKB, MINT, and/or STRING About this table 1 Gene Ontology (GO) biological process term (links to tree view) :
About this table
Drugs & Compounds for OLA1 (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
Sigma-Aldrich , Tocris Bioscience , and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB )
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Browse Tocris compounds for OLA1
Transcripts for OLA1(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
non coding RNAs according to
RNAdb ,
ESTs according to GeneTide ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from Invitrogen ,
Millipore , and/or
Abnova ,
siRNAs from Applied Biosystems ,
Sigma-Aldrich ,
shRNA from
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OriGene ,
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               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2 ): NM_001011708 Sigma-Aldrich siRNA for OLA1 Sigma-Aldrich shRNA for OLA1 Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer ® siRNAs: NM_001011708 NM_013341
REFSEQ mRNAs for OLA1 gene (2 alternative transcripts): NM_001011708.1 NM_013341.3
Applied Biosystems TaqMan ® Gene Expression Assays: NM_001011708 NM_013341
               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2 ): NM_001011708                                  Myc/DDK tagged cDNA clones in CMV expression vector (see all 2 ): NM_001011708                                  untagged cDNA clones in CMV expression vector (see all 3 ): NM_001011708  
Additional cDNA sequence: AF078859.1 AF078868.1 AF090946.1 AF134478.1 AK027523.1 AK074710.1 AK225112.1 AK225138.1 AK296339.1 AL136546.1 AL833441.1 BC012842.1 BC013925.1 BC029376.1 BC068447.1 BC091522.1 CR591506.1 CR594307.1 CR596070.1 CR603515.1 CR604617.1 CR604894.1 CR606753.1 CR606953.1 CR607181.1 CR607795.1 CR607845.1 CR608088.1 CR608516.1 CR613657.1 CR618778.1 CR618959.1 CR621118.1
24/29 DOTS entries (see all 29
): DT.75123637 DT.100880350 DT.100692069 DT.91777312 DT.120967622 DT.100766712 DT.100880345 DT.91777295 DT.100880343 DT.95368241 DT.100663964 DT.100880347 DT.120967581 DT.100880341 DT.100880351 DT.100880352 DT.102834815 DT.120667025 DT.120967580 DT.120967585 DT.120967657 DT.120967666 DT.120967676 DT.91777309
24/540 AceView cDNA sequences (see all 540
):AA242978 AI082010 AA494127 BG700826 BM922070 BG501274 BU153539 CB131631 CB133682 AA307942 BQ437576 AA236854 CR596070 BG209293 AF134478 BI667004 BM904888 BM542668 BC029376 CA419824 AA019294 AA233500 CR604617 AA608631
Unigene Cluster for OLA1: Obg-like ATPase 1 Hs.157351 [show with all ESTs ] Unigene Representative Sequence: NM_013341 GeneLoc Exon Structure 5/9 Alternative Splicing Database (ASD) splice patterns (SP) for OLA1 (see all 9
) ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12a · 12b · 12c ^ 13a · 13b ^ 14 SP1 :                       -   -                   -         SP2 :           -             -   -                           SP3 :           -   -             -                           SP4 :           -   -           -   -                           SP5 :           -   -           -   -     -   -   -                  
About this scheme ECgene alternative splicing isoforms for OLA1 4 Ensembl transcripts including schematic representations : ENST00000344357
ENST00000409546
ENST00000284719
ENST00000392560
Expression for OLA1
(Experimental results according to
1 GeneNote
and GNF BioGPS ,
probe sets-to-genes annotations according to
2 GeneAnnot ,
3 GeneTide ,
Sets of similar genes according to GeneDecks ,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP ,
plus additional links to
SOURCE , and/or
GNF
BioGPS , and/or
EXPOLDB , and/or
UniProtKB ,
Expression Assays from
Applied Biosystems
)
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OLA1 expression in normal and diseased human tissues Applied Biosystems TaqMan ® Gene Expression Assays for OLA1 1 / 2
6 probe-sets matching OLA1 gene Data from
(Publications) and GNF BioGPS About these images About these images CGAP SAGE TAG: TTTTACAGTASOURCE GeneReport for Unigene cluster: Hs.157351
Orthologs for OLA1
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
and/or
5 MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase ,
Gene Trees according to Ensembl )
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Orthologs for OLA1 gene from 5/28 species (see all 28
)
About this table Species with no ortholog for OLA1 ENSEMBL Gene Tree for OLA1 Paralogs for OLA1 (Paralogs according to 1 HomoloGene and 2 Ensembl , Pseudogenes according to 3 Pseudogene.org )About This Section
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--
SNPs/Variants for OLA1 (According to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE , and
UniProtKB ,
Linkage Disequilibrium by HapMap ,
Genotyping Reagents from
Applied Biosystems )
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HapMap Linkage Disequilibrium images for OLA1 (up to first 250kb)
Disorders & Mutations for OLA1
(in which this Gene is Involved, According to
OMIM, UniProtKB ,
PharmGKB ,
Genatlas , GeneTests ,
Blood group antigen gene mutations by BGMUT ,
HGMD, GAD ,
HuGE Navigator ,
BCGD ,
and/or TGDB .)
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OMIM: 611175
Medical News for OLA1 (Possibly Related Articles in
Doctor's Guide )
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Publications for OLA1 (in
PubMed .
Associations of this gene to articles via
1 Novoseek ,
2 HGNC ,
3 Entrez Gene ,
4 UniProtKB/Swiss-Prot ,
5 UniProtKB/TrEMBL ,
6 GAD , and/or
7 PharmGKB )
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10/14 PubMed articles for OLA1 gene (see all 14
):
Search for OLA1
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing OLA1
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
and/or
H-InvDB )
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Other Databases showing OLA1
(According to HUGE )
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Specialized Databases showing OLA1 (According to ATLAS , HORDE , IMGT , MTDB, LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
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-- Services for OLA1 (Reagents available from Applied Biosystems , Antibodies and assays by Cell
Signaling Technology , Abcam , Novus Biologicals ,Sigma-Aldrich , R&D Systems , Millipore , Abnova , and/or Invitrogen , Clones available from OriGene ,and/or Invitrogen , Drugs and/or compounds by Sigma-Aldrich , Enzo Life Sciences , and/or Tocris Bioscience )About This Section
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