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Aliases for OIP5-AS1 Gene

Subcategory (RNA class) for OIP5-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for OIP5-AS1 Gene

  • OIP5 Antisense RNA 1 2 3 5
  • OIP5 Antisense RNA 1 (Non-Protein Coding) 2 3
  • Linc-OIP5 3
  • Cyrano 3

External Ids for OIP5-AS1 Gene

Previous GeneCards Identifiers for OIP5-AS1 Gene

  • GC15P041577

Summaries for OIP5-AS1 Gene

Entrez Gene Summary for OIP5-AS1 Gene

  • This is a conserved gene that produces a long non-coding RNA that maintains cell proliferation in embryonic stem cells. This RNA can bind to and negatively regulate the activity of multiple cellular RNAs and microRNAs, including cyclin G associated kinase and ELAV like RNA binding protein 1. [provided by RefSeq, Dec 2017]

GeneCards Summary for OIP5-AS1 Gene

OIP5-AS1 (OIP5 Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class.

Additional gene information for OIP5-AS1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OIP5-AS1 Gene

Genomics for OIP5-AS1 Gene

GeneHancer (GH) Regulatory Elements for OIP5-AS1 Gene

Promoters and enhancers for OIP5-AS1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15I041282 Promoter/Enhancer 1.6 Ensembl ENCODE 550.8 +0.8 807 3.7 HDGF PKNOX1 CLOCK SMAD1 ARID4B SIN3A DMAP1 ZNF2 YY1 POLR2B OIP5-AS1 NDUFAF1 INO80 MGA GANC BAHD1 ENSG00000259211 RPAP1 DNAJC17 LOC105370795
GH15I040959 Enhancer 0.7 ENCODE dbSUPER 11 -323.4 -323388 1.8 ZFHX2 SMARCC1 POLR2A MAX ZIC2 EGR2 ZBTB17 LOC105370789 OIP5-AS1 NDUFAF1 EHD4-AS1 SPINT1 GC15M040957
GH15I040856 Enhancer 1.3 Ensembl ENCODE dbSUPER 4.4 -425.7 -425744 3.5 HDGF PKNOX1 ARID4B SIN3A ZNF2 IRF4 GLIS2 ZNF207 ZNF143 RUNX3 GC15P040864 GC15P040858 ZFYVE19 CCDC32 SPINT1 OIP5-AS1 RHOV
GH15I041232 Enhancer 0.9 ENCODE 5.3 -50.4 -50419 1.3 PKNOX1 ATF1 ARNT TCF12 GATA2 FOS ATF7 NCOA1 MBD2 MEF2D NDUFAF1 ZFYVE19 OIP5-AS1 EXD1 CHP1 GC15M041261 GC15M041262 GC15M041264 GC15M041265 GC15M041266
GH15I040850 Enhancer 0.8 ENCODE dbSUPER 5.7 -433.0 -432992 1.3 TFAP4 SAP130 SP5 ZNF644 RARA TEAD3 NFIL3 NR2F6 SMAD4 RXRB OIP5-AS1 GC15P040858 GC15P040864 SPINT1-AS1 SPINT1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around OIP5-AS1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for OIP5-AS1 Gene

Genomic Locations for OIP5-AS1 Gene
chr15:41,283,990-41,309,737
(GRCh38/hg38)
Size:
25,748 bases
Orientation:
Plus strand
chr15:41,576,188-41,601,901
(GRCh37/hg19)

Genomic View for OIP5-AS1 Gene

Genes around OIP5-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OIP5-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OIP5-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OIP5-AS1 Gene

Proteins for OIP5-AS1 Gene

Post-translational modifications for OIP5-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for OIP5-AS1 Gene

Domains & Families for OIP5-AS1 Gene

Gene Families for OIP5-AS1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with OIP5-AS1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for OIP5-AS1 Gene

Function for OIP5-AS1 Gene

Phenotypes for OIP5-AS1 Gene

GenomeRNAi human phenotypes for OIP5-AS1:
genes like me logo Genes that share phenotypes with OIP5-AS1: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OIP5-AS1 Gene

Localization for OIP5-AS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for OIP5-AS1 Gene

Pathways & Interactions for OIP5-AS1 Gene

SuperPathways for OIP5-AS1 Gene

No Data Available

Interacting Proteins for OIP5-AS1 Gene

Gene Ontology (GO) - Biological Process for OIP5-AS1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for OIP5-AS1 Gene

Drugs & Compounds for OIP5-AS1 Gene

No Compound Related Data Available

Transcripts for OIP5-AS1 Gene

mRNA/cDNA for OIP5-AS1 Gene

(6) Additional mRNA sequences :
(10) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OIP5-AS1 Gene

OIP5 antisense RNA 1:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for OIP5-AS1 Gene

No ASD Table

Relevant External Links for OIP5-AS1 Gene

GeneLoc Exon Structure for
OIP5-AS1
ECgene alternative splicing isoforms for
OIP5-AS1

Expression for OIP5-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OIP5-AS1 Gene

mRNA differential expression in normal tissues according to GTEx for OIP5-AS1 Gene

This gene is overexpressed in Brain - Cerebellar Hemisphere (x5.2).

SOURCE GeneReport for Unigene cluster for OIP5-AS1 Gene:

Hs.380164
genes like me logo Genes that share expression patterns with OIP5-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OIP5-AS1 Gene

Orthologs for OIP5-AS1 Gene

Evolution for OIP5-AS1 Gene

ENSEMBL:
Gene Tree for OIP5-AS1 (if available)
TreeFam:
Gene Tree for OIP5-AS1 (if available)

No data available for Orthologs for OIP5-AS1 Gene

Paralogs for OIP5-AS1 Gene

No data available for Paralogs for OIP5-AS1 Gene

Variants for OIP5-AS1 Gene

Sequence variations from dbSNP and Humsavar for OIP5-AS1 Gene

SNP ID Clin Chr 15 pos Variation AA Info Type
rs1000026988 -- 41,297,796(+) C/A intron_variant
rs1000039379 -- 41,292,940(+) G/A intron_variant
rs1000173812 -- 41,298,295(+) A/G non_coding_transcript_variant
rs1000204348 -- 41,282,084(+) C/T upstream_transcript_variant
rs1000547188 -- 41,288,030(+) C/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for OIP5-AS1 Gene

Variant ID Type Subtype PubMed ID
dgv2580n100 CNV gain 25217958
esv3552361 CNV deletion 23714750
nsv1045455 CNV gain 25217958
nsv1113704 CNV deletion 24896259
nsv952612 CNV duplication 24416366
nsv984057 CNV duplication 23825009

Additional Variant Information for OIP5-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OIP5-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for OIP5-AS1 Gene

Disorders for OIP5-AS1 Gene

Additional Disease Information for OIP5-AS1

No disorders were found for OIP5-AS1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OIP5-AS1 Gene

Publications for OIP5-AS1 Gene

  1. Knockdown of linc-OIP5 inhibits proliferation and migration of glioma cells through down-regulation of YAP-NOTCH signaling pathway. (PMID: 28189759) Hu GW … Lang HL (Gene 2017) 2 3 58
  2. Conserved function of lincRNAs in vertebrate embryonic development despite rapid sequence evolution. (PMID: 22196729) Ulitsky I … Bartel DP (Cell 2011) 2 3 58
  3. Long non-coding RNA OIP5-AS1 functions as an oncogene in lung adenocarcinoma through targeting miR-448/Bcl-2. (PMID: 29247949) Deng J … Wang S (Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018) 3 58
  4. The Long Noncoding RNA OIP5-AS1 Is Involved in the Regulation of Cell Proliferation. (PMID: 29277759) Naemura M … Kotake Y (Anticancer research 2018) 3 58
  5. LncRNA OIP5-AS1/cyrano suppresses GAK expression to control mitosis. (PMID: 28472763) Kim J … Gorospe M (Oncotarget 2017) 3 58

Products for OIP5-AS1 Gene

Sources for OIP5-AS1 Gene

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