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OIP5 Gene

protein-coding   GIFtS: 51
GCID: GC15M041601

Opa Interacting Protein 5

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Opa Interacting Protein 51 2     5730547N13Rik2
Cancer/Testis Antigen 861 2 3     LINT-252
Opa-Interacting Protein 52 3     MIS18beta2
CT862 3     hMIS18beta2
MIS18B2 3     LAP2alpha Interactor-252
OIP-52 3     MIS18 Kinetochore Protein Homolog B2
MIS18 Kinetochore Protein Homolog B (S. Pombe)1     Protein Mis18-Beta2

External Ids:    HGNC: 203001   Entrez Gene: 113392   Ensembl: ENSG000001041477   OMIM: 6060205   UniProtKB: O434823   

Export aliases for OIP5 gene to outside databases

Previous GC identifers: GC15M036969 GC15M034497 GC15M039180 GC15M039317 GC15M039389 GC15M018455


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for OIP5 Gene:
OIP5 (Opa interacting protein 5) is a protein-coding gene.

UniProtKB/Swiss-Prot: MS18B_HUMAN, O43482
Function: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000015.9  NC_018926.2  NT_010194.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the OIP5 gene promoter:
         Bach1   Pax-5   Bach2   MyoD   AREB6   Cart-1   NF-Y   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidOIP5 promoter sequence
   Search Chromatin IP Primers for OIP5

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat OIP5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q15.1   Ensembl cytogenetic band:  15q15.1   HGNC cytogenetic band: 15q14

OIP5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
OIP5 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15M041601:  view genomic region     (about GC identifiers)

Start:
41,601,466 bp from pter      End:
41,624,819 bp from pter
Size:
23,354 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: MS18B_HUMAN, O43482 (See protein sequence)
Recommended Name: Protein Mis18-beta  
Size: 229 amino acids; 24691 Da
Subunit: Homodimer, and heterodimer with MIS18A. Identified in a complex containing MIS18A, MIS18B, MIS18BP1,
RBBP7 and RBBP4. Binds outer membrane protein OpaP from Neisseria gonorrhoeae
Sequence caution: Sequence=AAC39561.1; Type=Erroneous initiation;
Secondary accessions: Q96BX7

Explore the universe of human proteins at neXtProt for OIP5: NX_O43482

Explore proteomics data for OIP5 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys215, Lys226
  • Modification sites at PhosphoSitePlus

  • See OIP5 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_009211.1  
    ENSEMBL proteins: 
     ENSP00000220514   ENSP00000452851  
    Reactome Protein details: O43482

    OIP5 Human Recombinant Protein Products:

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    Novus Biologicals OIP5 Protein
    Novus Biologicals OIP5 Lysates
    Browse Sino Biological Recombinant Proteins
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    Cloud-Clone Corp. Proteins for OIP5

     
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    antibodies-online proteins for OIP5 (4 products) 

     
    Search antibodies-online for peptides for OIP5

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    Abcam antibodies for OIP5
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    Search ThermoFisher Antibodies for OIP5
    antibodies-online antibodies for OIP5 (10 products) 

    OIP5 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for OIP5
    Cloud-Clone Corp. CLIAs for OIP5
    Search eBioscience for ELISAs for OIP5 
    antibodies-online kits for OIP5 (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR004910 Yippee/Mis18

    Graphical View of Domain Structure for InterPro Entry O43482

    ProtoNet protein and cluster: O43482


    Find genes that share domains with OIP5           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MS18B_HUMAN, O43482
    Function: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI12620389
         
    Find genes that share ontologies with OIP5           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for OIP5:
     Synthetic lethal with Ras 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for OIP5

    miRNA
    Products:
        
    miRTarBase miRNAs that target OIP5:
    hsa-mir-193b-3p (MIRT016268), hsa-mir-103a-3p (MIRT026997), hsa-mir-29c-3p (MIRT020369), hsa-mir-16-5p (MIRT031576)

    Block miRNA regulation of human, mouse, rat OIP5 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate OIP5:
    hsa-miR-664
    SwitchGear 3'UTR luciferase reporter plasmidOIP5 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for OIP5
    Predesigned siRNA for gene silencing in human, mouse, rat OIP5

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for OIP5

    Clone
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    OriGene clones in human, mouse for OIP5 (see all 6)
    OriGene ORF clones in mouse, rat for OIP5
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: OIP5 (NM_007280)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for OIP5
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OIP5

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for OIP5 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OIP5


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    MS18B_HUMAN, O43482: Nucleus. Chromosome. Chromosome, centromere. Note=Associated with centromeres in interphase
    cells, from late anaphase to the G1 phase. Not detected on centromeres during earlier phases of mitosis.
    Associated with chromatin
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol3
    extracellular1
    mitochondrion1
    peroxisome1

    Gene Ontology (GO): Selected cellular component terms (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000775chromosome, centromeric region IEA--
    GO:0000785chromatin IDA17284516
    GO:0005634nucleus IDA--
    GO:0005654nucleoplasm TAS--
    GO:0005730NOT nucleolus IDA--

    Find genes that share ontologies with OIP5           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for OIP5 About    
    See pathways by source

    SuperPathContained pathways About
    1Packaging Of Telomere Ends
    Chromosome Maintenance0.62
    Deposition of New CENPA-containing Nucleosomes at the Centromere0.59
    Nucleosome assembly0.59
    2Cell Cycle, Mitotic
    Cell Cycle0.90


    Find genes that share SuperPaths with OIP5           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for OIP5
        Deposition of new CENPA-containing nucleosomes at the centromere


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for OIP5
    Interactions:

        Search GeneGlobe Interaction Network for OIP5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for OIP5 (O434821, 3 ENSP000002205144) via UniProtKB, MINT, STRING, and/or I2D (see all 30)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RAF1P040491, 3, ENSP000002518494EBI-536879,EBI-365996 I2D: score=5 STRING: ENSP00000251849
    MIS18AQ9NYP93, ENSP000002901304I2D: score=1 STRING: ENSP00000290130
    BRAFP150563, ENSP000002886024I2D: score=4 STRING: ENSP00000288602
    CASC5ENSP000003354634STRING: ENSP00000335463
    CENPAENSP000003368684STRING: ENSP00000336868
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006334nucleosome assembly TAS--
    GO:0007067mitosis IEA--
    GO:0007154cell communication NAS9466265
    GO:0034080CENP-A containing nucleosome assembly at centromere TAS--

    Find genes that share ontologies with OIP5           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for OIP5 (MS18B)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for OIP5 gene: 
    NM_007280.1  

    Unigene Cluster for OIP5:

    Opa interacting protein 5
    Hs.661645  [show with all ESTs]
    Unigene Representative Sequence: BQ218042
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000220514(uc001znp.3) ENST00000560640
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat OIP5 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate OIP5:
    hsa-miR-664
    SwitchGear 3'UTR luciferase reporter plasmidOIP5 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for OIP5
    Predesigned siRNA for gene silencing in human, mouse, rat OIP5
    Clone
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    OriGene clones in human, mouse for OIP5 (see all 6)
    OriGene ORF clones in mouse, rat for OIP5
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: OIP5 (NM_007280)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for OIP5
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OIP5
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for OIP5
    OriGene qSTAR qPCR primer pairs in human, mouse for OIP5
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat OIP5
      QuantiTect SYBR Green Assays in human, mouse, rat OIP5
      QuantiFast Probe-based Assays in human, mouse, rat OIP5

    Additional mRNA sequence: 

    AF025441.1 BC015050.1 

    4 DOTS entries:

    DT.111704  DT.121040770  DT.306624  DT.95279554 

    Selected AceView cDNA sequences (see all 51):

    BE778254 CB157707 BU620714 AI953118 BE048189 BM762104 AF025441 BC015050 
    BM784603 CR603974 BQ651609 NM_007280 BG503804 AA767724 BM806431 AA281281 
    BQ217755 BF035661 BQ435353 BM848631 BE882633 AI498942 AI394114 AL551053 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for OIP5    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b
    SP1:                                          
    SP2:                    -                     


    ECgene alternative splicing isoforms for OIP5

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    OIP5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAGCAGTTGT
    OIP5 Expression
    About this image


    OIP5 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Ovary (Reproductive System)
             Secondary Oocyte Antral Follicle
     
     Gonad
             Secondary Oocyte Antral Follicle
    OIP5 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    OIP5 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.661645
        Custom PCR Arrays for OIP5
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OIP5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for OIP5 gene from Selected species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Oip51 , 5 Opa interacting protein 51, 5 80.13(n)1
    71.72(a)1
      2 (59.97 cM)5
    706451  NM_001042653.11  NP_001036118.11 
     1196095125 
    chicken
    (Gallus gallus)
    Aves OIP51 Opa interacting protein 5 57(n)
    46.15(a)
      423212  NM_001199658.1  NP_001186587.1 
    zebrafish
    (Danio rerio)
    Actinopterygii oip56
    opa interacting protein 5
    27(a)
    1 ↔ 1
    13(33480449-33483401) ENSDARG00000093597


    ENSEMBL Gene Tree for OIP5 (if available)
    TreeFam Gene Tree for OIP5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for OIP5 gene

    Find genes that share paralogs with OIP5           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for OIP5
    PGOHUM00000241696


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for OIP5 (see all 439)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1128271931,2
    C,F--41601044(+) GGTGCG/ACACCA 1 -- int11Minor allele frequency- A:0.50CSA 2
    rs1914658951,2
    --41601105(+) TTGGCA/GAGGCT 1 -- int10--------
    rs1505780441,2
    --41601127(+) CCTGAC/TCTCAA 1 -- int10--------
    rs781627421,2
    C,F--41601148(+) GCCTCG/AGCCTC 1 -- int11Minor allele frequency- A:0.02NA 120
    rs1396322701,2
    --41601162(+) AAATCC/TGGAAT 1 -- int10--------
    rs1829630811,2
    C--41601186(+) CACTGC/TGCCAG 1 -- int10--------
    rs1871646421,2
    --41601274(+) GTCTAA/TTTTTG 1 -- int10--------
    rs1914951701,2
    --41601406(+) GTTTCA/GTTTTA 1 -- int10--------
    rs1417132281,2
    --41601446(+) TCAGTC/TTACAA 1 -- int10--------
    rs1835230741,2
    --41601551(+) TATTAA/GTATTC 1 -- ut310--------

    HapMap Linkage Disequilibrium report for OIP5 (41601466 - 41624819 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for OIP5:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2661625CNV Deletion23128226
    esv2749606CNV Deletion23290073
    esv2667320CNV Deletion23128226
    esv25344CNV Gain19812545

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing OIP5
    DNA2.0 Custom Variant and Variant Library Synthesis for OIP5

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 606020    OMIM disorders: --


    Find genes that share disorders with OIP5           About GenesLikeMe


    Export disorders for OIP5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for OIP5 gene, integrated from 10 sources (see all 20):
    (articles sorted by number of sources associating them with OIP5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Priming of centromere for CENP-A recruitment by human hMis18alpha, hMis18beta, and M18BP1. (PubMed id 17199038)1, 2, 3 Fujita Y....Yanagida M. (Dev. Cell 2007)
    2. Using the yeast two-hybrid system to identify human epithelial cell proteins that bind gonococcal Opa proteins: intracellular gonococci bind pyruvate kinase via their Opa proteins and require host pyruvate for growth. (PubMed id 9466265)1, 2, 3 Williams J.M.... Rest R.F. (Mol. Microbiol. 1998)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. OIP5 is a highly expressed potential therapeutic target for colorectal and gastric cancers. (PubMed id 20510019)1, 9 Chun H.K....Lee H.G. (BMB Rep 2010)
    5. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    6. A Y2H-seq approach defines the human protein methyltransferase interactome. (PubMed id 23455924)1 Weimann M.... Stelzl U. (Nat. Methods 2013)
    7. Expression analysis of four testis-specific genes AURKC, OIP5, PIWIL2 and TAF7L in acute myeloid leukemia: a gender-dependent expression pattern. (PubMed id 23292864)1 Yazarloo F....Modarressi M.H. (Med. Oncol. 2013)
    8. Characterization of an Opa interacting protein 5 involved in lung and esophageal carcinogenesis. (PubMed id 22129094)1 Koinuma J....Daigo Y. (Cancer Sci. 2012)
    9. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    10. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    NCBI Bookshelf
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 11339 HGNC: 20300 AceView: OIP5 Ensembl:ENSG00000104147 euGenes: HUgn11339
    ECgene: OIP5 H-InvDB: OIP5

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for OIP5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for OIP5 gene:
    Search GeneIP for patents involving OIP5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
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