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Aliases & Descriptions for OIP5
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase) About This Section
|
| Aliases |
|---|
| 5730547N13Rik 2 | | CT86 3 | | LINT-25 2 | | MIS18B 3 | | MIS18beta 2 |
| | | Descriptions |
|---|
| Cancer/testis antigen 86 3 | | LAP2alpha interactor-25 2 | | Opa interacting protein 5 2 | | Opa-interacting protein 5 3 |
|
| | Search outside databases for aliases for OIP5 genePrevious GC identifers: GC15M036969 GC15M034497 GC15M039180 GC15M039317 |
Summaries for OIP5(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: MS18B_HUMAN, O43482Function: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis |
Genomic Location for OIP5
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences) About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Transcription factor binding sites upstream to the OIP5 gene 
Entrez Gene cytogenetic band: 15q15.1 Ensembl cytogenetic band: 15q15.1 HGNC cytogenetic band: 15q14OIP5 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)
 GeneLoc gene densities for chromosome 15 GeneLoc Exon Structure GeneLoc location for GC15M039389:
(about GC identifiers)
Start:
|
39,388,758 bp from pter |
End:
|
39,412,111 bp from pter |
Size:
|
23,354 bases |
Orientation:
|
minus strand |
RefSeq DNA sequence:- NC_000015.8 NT_010194.16
| Proteins for OIP5
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: MS18B_HUMAN, O43482 (See
protein sequence)Recommended Name: Protein Mis18-beta Size: 229 amino acids; 24691 Da
Subunit: Homodimer, and heterodimer with MIS18A. Identified in a complex containing MIS18A, MIS18B, MIS18BP1, RBBP7 and RBBP4. Binds outer membrane protein OpaP from Neisseria gonorrhoeae
Subcellular location: Nucleus. Centromere. Note=Associated with centromeres in interphase cells, from late anaphase to the G1 phase. Not detected on centromeres during earlier phases of mitosis. Associated with chromatin
Secondary accessions: Q96BX7Post-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins: NP_009211.1
ENSEMBL proteins: ENSP00000220514
Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 
5/6 Gene Ontology (GO) cellular component terms (links to tree view) (see all 6
): About this table
Antibodies for OIP5: Assays for OIP5: | Protein
Domains/ Families for OIP5(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: O43482 | Gene Function for OIP5
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_007280
Applied Biosystems Silencer® siRNAs for OIP5
Sigma-Aldrich siRNA for OIP5  Sigma-Aldrich shRNA for OIP5  Explore Sigma-Aldrich super-pooled esiRNAs 
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_007280                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_007280                                  untagged cDNA clone in CMV expression vector: NM_007280 
Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_007280
UniProtKB/Swiss-Prot: MS18B_HUMAN, O43482Function: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis1 Gene Ontology (GO) molecular function term (links to tree view): About this table | Pathways & Interactions for OIP5
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
5 Interacting proteins for OIP5 (ENSP000002205143 O434821) via UniProtKB, MINT, and/or STRINGAbout this table
4 Gene Ontology (GO) biological process terms (links to tree view): About this table
|
Drugs & Compounds for OIP5(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
Browse Tocris compounds for OIP5
|
Transcripts for OIP5(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene, Expression Assays from Applied Biosystems) About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_007280
Sigma-Aldrich siRNA for OIP5  Sigma-Aldrich shRNA for OIP5  Explore Sigma-Aldrich super-pooled esiRNAs 
Applied Biosystems Silencer® siRNAs: NM_007280 REFSEQ mRNAs for OIP5 gene: NM_007280.1
Applied Biosystems TaqMan ® Gene Expression Assays: NM_007280               OriGene GFP tagged cDNA clone in CMV expression vector: NM_007280                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_007280                                  untagged cDNA clone in CMV expression vector: NM_007280  Additional cDNA sequence: AF025441.1 BC015050.1 CR603974.1 4 DOTS entries: DT.111704 DT.121040770 DT.306624 DT.95279554 24/51 AceView cDNA sequences (see all 51
):BM784603 BU620714 BE778254 AF025441 AI953118 AA767724 BG503804 CR603974 BM762104 BE048189 NM_007280 BQ651609 CB157707 BC015050 AA743696 BM846325 BQ217755 AI394114 BF035661 BE385809 BI552750 BG498569 AW957943 BM806431
highest scoring ESTs for OIP5:AF025441 AA308351 AL574729 AW957943 BC015050 BE048189 BE385809 BE567716 BE778254 BE882633 Unigene Cluster for OIP5: Opa interacting protein 5 Hs.661645 [show with all ESTs]Unigene Representative Sequence: BQ218042
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for OIP5
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | - |   | |   | |   | |   |
About this scheme
ECgene alternative splicing isoforms for OIP5
1 Ensembl transcript including schematic representation: ENST00000220514
|
Expression for OIP5
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| OIP5 expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for OIP5
1 / 2 / 3 3 probe-sets matching OIP5 gene Data from
(Publications) and GNF BioGPS About these images About these images
CGAP SAGE TAG: GAGCAGTTGT
SOURCE GeneReport for Unigene cluster: Hs.661645
Expression variation in blood from EXPOLDB for OIP5 |
Orthologs for OIP5
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for OIP5 gene from 5/6 species (see all 6
)
About this table Species with no ortholog for OIP5
ENSEMBL Gene Tree for OIP5 | Paralogs for OIP5(Paralogs according to 1HomoloGene and 2Ensembl, Pseudogenes according to 3Pseudogene.org) About This Section
| -- |
SNPs/Variants for OIP5(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for OIP5 (up to first 250kb)
|
Disorders & Mutations for OIP5
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
|
OMIM: 606020
|
Medical News for OIP5(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications for OIP5 (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 7 PubMed articles for OIP5 gene: |
Search for OIP5
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing OIP5
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing OIP5
(According to HUGE)
About This Section
| -- |
Specialized Databases showing OIP5(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| About This Section
| --
| Services for OIP5(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals, Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience) About This Section
| 
 Products for OIP5:

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| | Recombinant Proteins (OIP5) | | Antibodies (OIP5) |
| | | Search Tocris compounds for OIP5 |
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Incremental update: 13 Oct 2009
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