Aliases for OIP5 Gene
External Ids for OIP5 Gene
Previous GeneCards Identifiers for OIP5 Gene
The protein encoded by this gene localizes to centromeres, where it is essential for recruitment of CENP-A through the mediator Holliday junction recognition protein. Expression of this gene is upregulated in several cancers, making it a putative therapeutic target. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]
GeneCards Summary for OIP5 Gene
UniProtKB/Swiss-Prot for OIP5 Gene
Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.