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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

OIP5 Gene

protein-coding   GIFtS: 49
GCID: GC15M041601

Opa Interacting Protein 5

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Opa Interacting Protein 51 2     5730547N13Rik2
Cancer/Testis Antigen 861 2 3     LINT-252
Opa-Interacting Protein 52 3     MIS18beta2
CT862 3     hMIS18beta2
MIS18B2 3     LAP2alpha Interactor-252
OIP-52 3     MIS18 Kinetochore Protein Homolog B2
MIS18 Kinetochore Protein Homolog B (S. Pombe)1     Protein Mis18-Beta2

External Ids:    HGNC: 203001   Entrez Gene: 113392   Ensembl: ENSG000001041477   OMIM: 6060205   UniProtKB: O434823   

Export aliases for OIP5 gene to outside databases

Previous GC identifers: GC15M036969 GC15M034497 GC15M039180 GC15M039317 GC15M039389 GC15M018455


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for OIP5 Gene: 
OIP5 (Opa interacting protein 5) is a protein-coding gene. Diseases associated with OIP5 include gastric cancer, and esophagitis, and among its related super-pathways are Packaging Of Telomere Ends and Cell Cycle, Mitotic. GO annotations related to this gene include protein binding.

UniProtKB/Swiss-Prot: MS18B_HUMAN, O43482
Function: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000015.9  NC_018926.2  NT_010194.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the OIP5 gene promoter:
         Bach1   Pax-5   Bach2   MyoD   AREB6   Cart-1   NF-Y   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidOIP5 promoter sequence
   Search SABiosciences Chromatin IP Primers for OIP5

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OIP5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q15.1   Ensembl cytogenetic band:  15q15.1   HGNC cytogenetic band: 15q14

OIP5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
OIP5 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15M041601:  view genomic region     (about GC identifiers)

Start:
41,601,466 bp from pter      End:
41,624,819 bp from pter
Size:
23,354 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: MS18B_HUMAN, O43482 (See protein sequence)
Recommended Name: Protein Mis18-beta  
Size: 229 amino acids; 24691 Da
Subunit: Homodimer, and heterodimer with MIS18A. Identified in a complex containing MIS18A, MIS18B, MIS18BP1,
RBBP7 and RBBP4. Binds outer membrane protein OpaP from Neisseria gonorrhoeae
Subcellular location: Nucleus. Chromosome. Chromosome, centromere. Note=Associated with centromeres in interphase
cells, from late anaphase to the G1 phase. Not detected on centromeres during earlier phases of mitosis.
Associated with chromatin
Sequence caution: Sequence=AAC39561.1; Type=Erroneous initiation;
Secondary accessions: Q96BX7

Explore the universe of human proteins at neXtProt for OIP5: NX_O43482

Explore proteomics data for OIP5 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O43482

  • OIP5 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    OIP5 Protein Expression
    REFSEQ proteins: NP_009211.1  
    ENSEMBL proteins: 
     ENSP00000220514   ENSP00000452851  
    Reactome Protein details: O43482
    Human Recombinant Protein Products for OIP5: 
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for OIP5 

    Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000775chromosome, centromeric region IEA--
    GO:0000785chromatin IDA17284516
    GO:0005634nucleus IDA17284516
    GO:0005654nucleoplasm TAS--
    GO:0010369chromocenter IEA--

    OIP5 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ProtoNet protein and cluster: O43482


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MS18B_HUMAN, O43482
    Function: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI12620389
         
    OIP5 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for OIP5:
     Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for OIP5 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for OIP5

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for OIP5 
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate OIP5:
    hsa-miR-664
    SwitchGear 3'UTR luciferase reporter plasmidOIP5 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OIP5


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for OIP5 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Packaging Of Telomere Ends
    Nucleosome assembly0.46
    Deposition of New CENPA-containing Nucleosomes at the Centromere0.46
    2Cell Cycle
    Cell Cycle0.84
    3Meiotic Synapsis
    Chromosome Maintenance0.56

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    4        Reactome Pathways for OIP5
        Nucleosome assembly
    Cell Cycle
    Deposition of New CENPA-containing Nucleosomes at the Centromere
    Chromosome Maintenance



    OIP5 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for OIP5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/30 Interacting proteins for OIP5 (O434821, 3 ENSP000002205144) via UniProtKB, MINT, STRING, and/or I2D (see all 30)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RAF1P040491, 3, ENSP000002518494EBI-536879,EBI-365996 I2D: score=5 STRING: ENSP00000251849
    MIS18AQ9NYP93, ENSP000002901304I2D: score=1 STRING: ENSP00000290130
    BRAFP150563, ENSP000002886024I2D: score=4 STRING: ENSP00000288602
    CASC5ENSP000003354634STRING: ENSP00000335463
    CENPAENSP000003368684STRING: ENSP00000336868
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006334nucleosome assembly TAS--
    GO:0007067mitosis IEA--
    GO:0007154cell communication NAS9466265
    GO:0034080CENP-A containing nucleosome assembly at centromere TAS--
    GO:0051301cell division IEA--

    OIP5 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for OIP5 (MS18B)

    Search CenterWatch for drugs/clinical trials and news about OIP5 / MS18B

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for OIP5 gene: 
    NM_007280.1  

    Unigene Cluster for OIP5:

    Opa interacting protein 5
    Hs.661645  [show with all ESTs]
    Unigene Representative Sequence: BQ218042
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000220514(uc001znp.3) ENST00000560640
    miRNA
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate OIP5:
    hsa-miR-664
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    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OIP5
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                         Customized lentivirus expression plasmids for stable overexpression of OIP5 
    Primer
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OIP5

    Additional mRNA sequence: 

    AF025441.1 BC015050.1 

    4 DOTS entries:

    DT.111704  DT.121040770  DT.306624  DT.95279554 

    24/51 AceView cDNA sequences (see all 51):

    BM762104 CR603974 AA767724 BE048189 AI953118 BG503804 NM_007280 AF025441 
    BM784603 BU620714 BQ651609 CB157707 BC015050 BE778254 BU633371 BQ217755 
    BM848631 AI191782 BQ435353 AI394114 BM806431 BE385809 BI552750 AL551053 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for OIP5    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b
    SP1:                                          
    SP2:                    -                     


    ECgene alternative splicing isoforms for OIP5

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    OIP5 expression in normal human tissues (normalized intensities)      OIP5 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAGCAGTTGT
    OIP5 Expression
    About this image


    OIP5 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/2 selected tissues (see all 2) fully expand
     
     Ovary (Reproductive System)
             Secondary Oocyte Antral Follicle
     
     Gonad
             Secondary Oocyte Antral Follicle

    See OIP5 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for OIP5

    SOURCE GeneReport for Unigene cluster: Hs.661645
        SABiosciences Custom PCR Arrays for OIP5
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OIP5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for OIP5 gene from 3/8 species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Oip51 , 5 Opa interacting protein 51, 5 80.13(n)1
    71.72(a)1
      2 (59.97 cM)5
    706451  NM_001042653.11  NP_001036118.11 
     1196095125 
    chicken
    (Gallus gallus)
    Aves OIP51 Opa interacting protein 5 57.43(n)
    46.99(a)
      423212  NM_001199658.1  NP_001186587.1 
    zebrafish
    (Danio rerio)
    Actinopterygii oip56
    opa interacting protein 5
    26(a)
    1 ↔ 1
    13(33480449-33483401)


    ENSEMBL Gene Tree for OIP5 (if available)
    TreeFam Gene Tree for OIP5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for OIP5 gene

    OIP5 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for OIP5
    PGOHUM00000241696


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/439 SNPs in OIP5 are shown (see all 439)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1128271931,2
    C,F--41601044(+) GGTGCG/ACACCA 1 -- int11Minor allele frequency- A:0.50CSA 2
    rs1914658951,2
    --41601105(+) TTGGCA/GAGGCT 1 -- int10--------
    rs1505780441,2
    --41601127(+) CCTGAC/TCTCAA 1 -- int10--------
    rs781627421,2
    C,F--41601148(+) GCCTCG/AGCCTC 1 -- int11Minor allele frequency- A:0.02NA 120
    rs1396322701,2
    --41601162(+) AAATCC/TGGAAT 1 -- int10--------
    rs1829630811,2
    C--41601186(+) CACTGC/TGCCAG 1 -- int10--------
    rs1871646421,2
    --41601274(+) GTCTAA/TTTTTG 1 -- int10--------
    rs1914951701,2
    --41601406(+) GTTTCA/GTTTTA 1 -- int10--------
    rs1417132281,2
    --41601446(+) TCAGTC/TTACAA 1 -- int10--------
    rs1835230741,2
    --41601551(+) TATTAA/GTATTC 1 -- ut310--------

    HapMap Linkage Disequilibrium report for OIP5 (41601466 - 41624819 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for OIP5:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2661625CNV Deletion23128226
    esv2749606CNV Deletion23290073
    esv2667320CNV Deletion23128226
    esv25344CNV Gain19812545

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 606020    OMIM disorders: --

    2 diseases for OIP5:    About MalaCards
    gastric cancer    esophagitis


    OIP5 for disorders           About GeneDecksing


    Export disorders for OIP5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for OIP5 gene, integrated from 9 sources (see all 19):
    (articles sorted by number of sources associating them with OIP5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Priming of centromere for CENP-A recruitment by human hMis18alpha, hMis18beta, and M18BP1. (PubMed id 17199038)1, 2, 3 Fujita Y....Yanagida M. (2007)
    2. Using the yeast two-hybrid system to identify human epithelial cell proteins that bind gonococcal Opa proteins: intracellular gonococci bind pyruvate kinase via their Opa proteins and require host pyruvate for growth. (PubMed id 9466265)1, 2, 3 Williams J.M.... Rest R.F. (1998)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. OIP5 is a highly expressed potential therapeutic targ et for colorectal and gastric cancers. (PubMed id 20510019)1, 9 Chun H.K....Lee H.G. (2010)
    5. A Y2H-seq approach defines the human protein methyltransferase interactome. (PubMed id 23455924)1 Weimann M.... Stelzl U. (2013)
    6. Expression analysis of four testis-specific genes AURK C, OIP5, PIWIL2 and TAF7L in acute myeloid leukemia: a gender-dependent expressi on pattern. (PubMed id 23292864)1 Yazarloo F....Modarressi M.H. (2013)
    7. Characterization of an Opa interacting protein 5 invol ved in lung and esophageal carcinogenesis. (PubMed id 22129094)1 Koinuma J....Daigo Y. (2012)
    8. Toward an understanding of the protein interaction net work of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (2011)
    9. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    10. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
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    NCBI Bookshelf
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 11339 HGNC: 20300 AceView: OIP5 Ensembl:ENSG00000104147 euGenes: HUgn11339
    ECgene: OIP5 H-InvDB: OIP5

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for OIP5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for OIP5 gene:
    Search GeneIP for patents involving OIP5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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