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Aliases & Descriptions for OGFOD1
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc
, and/or 7 Ensembl ,
8 miRBase )About This Section
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Aliases EC 1.14.11.- 3 FLJ10826 1 , 2 KIAA1612 1 , 2 , 3 TPA1 1 , 2 , 3
Descriptions 2-oxoglutarate and iron-dependent oxygenase domain containing 1 2 TPA1, termination and polyadenylation 1, homolog 2 Termination and polyadenylation 1 homolog 3
Search outside databases for aliases for OGFOD1 gene
Summaries for OGFOD1 (According to Entrez Gene ,
Wikipedia's
Gene Wiki ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
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Genomic Location for OGFOD1
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 36) ,
and/or miRBase ,
Genomic Views according to
UCSC and
Ensembl ,
Transcription factor binding sites according to
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Genomic View : UCSC Golden Path with GeneCards custom track Transcription factor binding sites upstream to the OGFOD1 gene Entrez Gene cytogenetic band: 16q13 Ensembl cytogenetic band: 16q13 HGNC cytogenetic band: 16q12.2 OGFOD1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc gene densities for chromosome 16 GeneLoc Exon Structure
GeneLoc location for GC16P055043:
(about GC identifiers )
Start:
55,042,925 bp from pter
End:
55,068,908 bp from pter
Size:
25,984 bases
Orientation:
plus strand
RefSeq DNA sequence: NC_000016.8 NT_010498.15 Proteins for OGFOD1
(According to
1 UniProtKB ,
and/or Ensembl ,
Phosphorylation sites according to 2 Phosphosite ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Enzo Life Sciences ,
Abnova ,
OriGene and/or,
Abcam ,
Biochemical Assays by
Invitrogen ,
Millipore ,
R&D Systems ,
Cell Signaling Technology , and/or
Enzo Life Sciences ,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene ,
Antibodies by Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Cell Signaling Technology ,
Abcam ,
Abnova , and/or
Novus Biologicals )
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UniProtKB/Swiss-Prot: OGFD1_HUMAN, Q8N543 (See
protein sequence )Recommended Name: 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1 Size : 542 amino acids; 63246 Da
Cofactor : Binds 1 Fe(2+) ion per subunit (By similarity)
Cofactor : Ascorbate (By similarity)
Secondary accessions : Q9H7U5 Q9H9J9 Q9HA87 Q9HCG0 Q9NVB6Alternative splicing : 2 isoforms : Q8N543-1 Q8N543-2
REFSEQ proteins: NP_060703.3 ENSEMBL proteins: ENSP00000337196 Human Recombinant Proteins               OriGene Purified Recombinant Human Protein: OGFOD1 2 Gene Ontology (GO) cellular component terms (links to tree view) :
About this table Antibodies for OGFOD1: Assays for OGFOD1:
Protein
Domains/ Families for OGFOD1(According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
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Graphical View of Domain Structure for InterPro Entry Q8N543 ProtoNet protein and cluster: Q8N543
UniProtKB/Swiss-Prot: OGFD1_HUMAN, Q8N543 Similarity : Belongs to the TPA1 familySimilarity : Contains 1 PKHD (prolyl/lysyl hydroxylase) domain
Gene Function for OGFOD1
(According to MGI Jun 06 2009, UniProtKB ,
IUBMB ,and/or Genatlas ,
shRNA from
OriGene ,
Sigma-Aldrich , RNAi from
Sigma-Aldrich ,
RNAi Products ,
Clones , and
Q-PCR Products
from Invitrogen ,
Millipore ,
OriGene , and/or
Abnova ,
siRNAs from
Applied Biosystems ,
SYBR primers from OriGene ,
Cell-based Assays from Millipore ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
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               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2 ): NM_018233 Applied Biosystems Silencer ® siRNAs for OGFOD1 Sigma-Aldrich siRNA for OGFOD1 Sigma-Aldrich shRNA for OGFOD1 Explore Sigma-Aldrich super-pooled esiRNAs               OriGene GFP tagged cDNA clone in CMV expression vector: NM_018233                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_018233                                  untagged cDNA clones in CMV expression vector (see all 3 ): AK022752  Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_001031707 5/6 Gene Ontology (GO) molecular function terms (links to tree view) (see all 6
):
GO ID Qualified GO term Evidence PubMed IDs GO:0005506 iron ion binding
IEA -- GO:0016491 oxidoreductase activity
IEA -- GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
IEA -- GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
IEA -- GO:0031418 L-ascorbic acid binding
IEA --
About this table
Pathways & Interactions for OGFOD1
(Pathways according to Invitrogen
(maps by GeneGo ),
Millipore ,
Cell Signaling Technology ,
Sigma-Aldrich ,
KEGG
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Proteins Network according to
SABiosciences ,
Interactions according to 1 UniProtKB ,
2 MINT , and/or
3 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
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--2 Gene Ontology (GO) biological process terms (links to tree view) :
GO ID Qualified GO term Evidence PubMed IDs GO:0019538 protein metabolic process
IEA -- GO:0055114 oxidation reduction
IEA --
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Drugs & Compounds for OGFOD1 (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
Sigma-Aldrich , Tocris Bioscience , and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB )
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Browse Tocris compounds for OGFOD1
Transcripts for OGFOD1(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
non coding RNAs according to
RNAdb ,
ESTs according to GeneTide ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from Invitrogen ,
Millipore , and/or
Abnova ,
siRNAs from Applied Biosystems ,
Sigma-Aldrich ,
shRNA from
Sigma-Aldrich ,
OriGene ,
Tagged/untagged cDNA clones from
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               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2 ): NM_018233 Sigma-Aldrich siRNA for OGFOD1 Sigma-Aldrich shRNA for OGFOD1 Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer ® siRNAs: NM_018233
REFSEQ mRNAs for OGFOD1 gene: NM_018233.3
Applied Biosystems TaqMan ® Gene Expression Assays: NM_018233
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_018233                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_018233                                  untagged cDNA clones in CMV expression vector (see all 3 ): AK022752  
Additional cDNA sequence: AK001688.1 AK022130.1 AK022752.1 AK024314.1 AK304584.1 BC032919.1 CR615197.1
16 DOTS entries : DT.100827819 DT.409937 DT.100827810 DT.101957248 DT.100827814 DT.95100255 DT.40286882 DT.92445989 DT.92445990 DT.100827821 DT.120658066 DT.91656989 DT.92046014 DT.120658043 DT.120658136 DT.99974119
24/212 AceView cDNA sequences (see all 212
):BQ004313 AA130350 BQ011602 AW009880 BM996096 BQ643178 BM827760 AL708454 AB046832 AA007182 BQ430151 AJ709422 BI520306 CA427497 AI817242 CB113222 BX327322 AI754257 AU134133 CR615197 BM470550 CB305602 AL711389 BQ424365
highest scoring ESTs for OGFOD1 :AI817242 AA100168 AA292623 AA476604 AA974480 AI537335 AI650554 AI795987 AI913817 AK001688
Unigene Cluster for OGFOD1: 2-oxoglutarate and iron-dependent oxygenase domain containing 1 Hs.231883 [show with all ESTs ] Unigene Representative Sequence: NM_018233 GeneLoc Exon Structure 5 Alternative Splicing Database (ASD) splice patterns (SP) for OGFOD1 ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 SP1 :               -                         SP2 :           -     -                         SP3 :               -                         SP4 :               -   -                       SP5 :                                      
About this scheme ECgene alternative splicing isoforms for OGFOD1 1 Ensembl transcript including schematic representation : ENST00000336111
Expression for OGFOD1
(Experimental results according to
1 GeneNote
and GNF BioGPS ,
probe sets-to-genes annotations according to
2 GeneAnnot ,
3 GeneTide ,
Sets of similar genes according to GeneDecks ,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP ,
plus additional links to
SOURCE , and/or
GNF
BioGPS , and/or
EXPOLDB , and/or
UniProtKB ,
Expression Assays from
Applied Biosystems
)
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OGFOD1 expression in normal and diseased human tissues Applied Biosystems TaqMan ® Gene Expression Assays for OGFOD1 1 / 2 / 3
11 probe-sets matching OGFOD1 gene Data from
(Publications) and GNF BioGPS About these images About these images CGAP SAGE TAG: --SOURCE GeneReport for Unigene cluster: Hs.231883
Orthologs for OGFOD1
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
and/or
5 MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase ,
Gene Trees according to Ensembl )
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Orthologs for OGFOD1 gene from 5/12 species (see all 12
)
About this table Species with no ortholog for OGFOD1 ENSEMBL Gene Tree for OGFOD1 Paralogs for OGFOD1 (Paralogs according to 1 HomoloGene and 2 Ensembl , Pseudogenes according to 3 Pseudogene.org )About This Section
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SNPs/Variants for OGFOD1 (According to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE , and
UniProtKB ,
Linkage Disequilibrium by HapMap ,
Genotyping Reagents from
Applied Biosystems )
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HapMap Linkage Disequilibrium images for OGFOD1 (up to first 250kb)
Disorders & Mutations for OGFOD1
(in which this Gene is Involved, According to
OMIM, UniProtKB ,
PharmGKB ,
Genatlas , GeneTests ,
Blood group antigen gene mutations by BGMUT ,
HGMD, GAD ,
HuGE Navigator ,
BCGD ,
and/or TGDB .)
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Medical News for OGFOD1 (Possibly Related Articles in
Doctor's Guide )
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Publications for OGFOD1 (in
PubMed .
Associations of this gene to articles via
1 Novoseek ,
2 HGNC ,
3 Entrez Gene ,
4 UniProtKB/Swiss-Prot ,
5 UniProtKB/TrEMBL ,
6 GAD , and/or
7 PharmGKB )
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5 PubMed articles for OGFOD1 gene :
Search for OGFOD1
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing OGFOD1
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
and/or
H-InvDB )
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Other Databases showing OGFOD1
(According to HUGE )
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Specialized Databases showing OGFOD1 (According to ATLAS , HORDE , IMGT , MTDB, LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
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-- Services for OGFOD1 (Reagents available from Applied Biosystems , Antibodies and assays by Cell
Signaling Technology , Abcam , Novus Biologicals ,Sigma-Aldrich , R&D Systems , Millipore , Abnova , and/or Invitrogen , Clones available from OriGene ,and/or Invitrogen , Drugs and/or compounds by Sigma-Aldrich , Enzo Life Sciences , and/or Tocris Bioscience )About This Section
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