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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

OGDHL Gene

protein-coding   GIFtS: 56
GCID: GC10M050942

oxoglutarate dehydrogenase-like

 Explore 5 diseases affiliated with
OGDHL via our new
 Human Malady Compendium 
Biological research products
for OGDHL
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Oxoglutarate Dehydrogenase-Like1 2     2-Oxoglutarate Dehydrogenase-Like, Mitochondrial2
Alpha-Ketoglutarate Dehydrogenase-Like2 3     EC 1.2.4.-3
2-Oxoglutarate Dehydrogenase Complex Component E1-Like2 3     KIAA12903
OGDC-E1-Like1     EC 1.2.4.28
FLJ108511     

External Ids:    HGNC: 255901   Entrez Gene: 557532   Ensembl: ENSG000001974447   UniProtKB: Q9ULD03   

Export aliases for OGDHL gene to outside databases

Previous GC identifers: GC10M050288 GC10M050612 GC10M045207


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

  --

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NC_018921.1  NT_030059.13  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the OGDHL gene promoter:
         GATA-3   HTF   NRSF form 1   Tal-1beta   NRSF form 2   E47   N-Myc   S8   POU2F1   POU2F1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidOGDHL promoter sequence
   Search SABiosciences Chromatin IP Primers for OGDHL

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OGDHL


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q11.23   Ensembl cytogenetic band:  10q11.23   HGNC chromosome: 10

OGDHL Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
OGDHL gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M050942:  view genomic region     (about GC identifiers)

Start:
50,942,687 bp from pter      End:
50,970,425 bp from pter
Size:
27,739 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: OGDHL_HUMAN, Q9ULD0 (See protein sequence)
Recommended Name: 2-oxoglutarate dehydrogenase-like, mitochondrial precursor  
Size: 1010 amino acids; 114481 Da
Cofactor: Thiamine pyrophosphate (By similarity)
Subcellular location: Mitochondrion matrix (By similarity)
Sequence caution: Sequence=BAA86604.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: A8K2G1 B4DKG2 B4E193 Q8TAN9 Q9NVA0
Alternative splicing: 3 isoforms:  Q9ULD0-1   Q9ULD0-2   Q9ULD0-3   

Explore the universe of human proteins at neXtProt for OGDHL: NX_Q9ULD0

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9ULD0

  • 4/29 DME Specific Peptides for OGDHL (Q9ULD0) (see all 29)
     RLSGQDV  GQAKWVR  DLVCYRR  KSLLRHP 

    OGDHL Protein expression data from MOPED and PaxDb:    About this image 
    OGDHL Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001137468.1  NP_001137469.1  NP_060715.2  

    ENSEMBL proteins: 
     ENSP00000363216   ENSP00000401356   ENSP00000390240  

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    Uscn Proteins for OGDHL

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005759mitochondrial matrix IEA--

    OGDHL for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    OGDHL for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR011603 2oxoglutarate_DH_E1
     IPR005475 Transketolase-like_Pyr-bd
     IPR001017 DH_E1

    Graphical View of Domain Structure for InterPro Entry Q9ULD0

    ProtoNet protein and cluster: Q9ULD0

    1 Blocks protein family: IPB005475 Transketolase

    UniProtKB/Swiss-Prot: OGDHL_HUMAN, Q9ULD0
    Similarity: Belongs to the alpha-ketoglutarate dehydrogenase family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:
         Genatlas biochemistry entry for OGDHL:
    alpha-ketoglutarate dehydrogenase,E1k subunit-like sequence

         Enzyme Numbers (IUBMB): EC 1.2.4.22 EC 1.2.4.-1

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004591oxoglutarate dehydrogenase (succinyl-transferring) activity IEA--
    GO:0005515protein binding IPI--
    GO:0030976thiamine pyrophosphate binding IEA--
         
    OGDHL for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for OGDHL:
     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for OGDHL 

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OGDHL


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Lysine degradation
    Lysine degradation1.00
    2TCA cycle II (eukaryotic)
    TCA cycle II (eukaryotic)1.00
    3TCA Cycle
    Citrate cycle (TCA cycle)0.65
    4Tryptophan metabolism
    Tryptophan metabolism0.47
    5Metabolism
    Metabolic pathways0.38

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 BioSystems Pathway for OGDHL 
        TCA cycle II (eukaryotic)


    4         Kegg Pathways  (Kegg details for OGDHL):
        Citrate cycle (TCA cycle)
    Lysine degradation
    Tryptophan metabolism
    Metabolic pathways


    OGDHL for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for OGDHL

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/31 Interacting proteins for OGDHL (Q9ULD01 ENSP000003632164) via UniProtKB, MINT, STRING, and/or I2D (see all 31)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    STAT3P407631, ENSP000002646574EBI-3940481,EBI-518675 STRING: ENSP00000264657
    AADATENSP000002268404STRING: ENSP00000226840
    IDH1ENSP000002609854STRING: ENSP00000260985
    IDH2ENSP000003318974STRING: ENSP00000331897
    IDH3BENSP000003702234STRING: ENSP00000370223
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006096glycolysis IEA--
    GO:0006099tricarboxylic acid cycle IEA--

    OGDHL for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for OGDHL

    10/12 HMDB Compounds for OGDHL (see all 12)    About this table
    CompoundSynonyms CAS #PubMed Ids
    2-Ketobutyric acid2-Ketobutanoate (see all 35)600-18-0--
    3-carboxy-1-hydroxypropylthiamine diphosphate3-Carboxy-1-hydroxypropyl-ThPP (see all 3)----
    Carbon dioxideCarbon oxide (see all 5)124-38-9--
    Coenzyme AAcetoacetyl coenzyme A sodium salt (see all 21)85-61-0--
    Glutaryl-CoAglutaryl-CoA (see all 2)103192-48-9--
    NAD3-Carbamoyl-1-D-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate (see all 28)53-84-9--
    NADH1,4-Dihydronicotinamide adenine dinucleotide (see all 17)58-68-4--
    Oxoadipic acidalpha-ketoadipic acid (see all 19)3184-35-8--
    Oxoglutaric acid2-Ketoglutarate (see all 9)328-50-7--
    S-Glutaryldihydrolipoamide ----
    Search CenterWatch for drugs/clinical trials and news about OGDHL 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for OGDHL gene (3 alternative transcripts): 
    NM_001143996.1  NM_001143997.1  NM_018245.2  

    Unigene Cluster for OGDHL:

    Oxoglutarate dehydrogenase-like
    Hs.17860  [show with all ESTs]
    Unigene Representative Sequence: NM_018245
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000374103(uc009xog.3 uc001jie.3 uc009xoh.2) ENST00000490844
    ENST00000496884 ENST00000471460 ENST00000419399(uc010qgt.2) ENST00000432695(uc010qgu.2)


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    hsa-miR-1263 hsa-miR-4263 hsa-miR-139-5p hsa-miR-138-1* hsa-miR-9 hsa-miR-659 hsa-miR-3622b-3p hsa-miR-377
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    Inhib. RNA
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    Additional cDNA sequence: 

    AB033116.3 AK001713.1 AK290226.1 AK296551.1 AK303729.1 AK307759.1 BC026320.1 

    9 DOTS entries:

    DT.412735  DT.95160623  DT.100777896  DT.100000713  DT.92452437  DT.95193102  DT.121290645  DT.92452444 
    DT.102826111 

    24/93 AceView cDNA sequences (see all 93):

    BX482149 BU165087 AW664293 CR603720 BF313582 AB033116 BU732141 CD671366 
    CD671333 BU787591 AW149004 BQ613930 AI289176 AA948651 AU133174 BX283119 
    AI215507 AI218254 N51727 BM504223 BU741802 CD629111 BX333646 AU159536 

    GeneLoc Exon Structure

    5/17 Alternative Splicing Database (ASD) splice patterns (SP) for OGDHL (see all 17)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c · 6d · 6e · 6f ^ 7 ^ 8a · 8b · 8c ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12a · 12b ^ 13a ·
    SP1:                          -     -     -           -                             -     -                                                     -               
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:              -     -     -     -     -     -     -                             -     -                                                                     
    SP5:                          -     -     -     -     -                             -     -                                                                     

    ExUns: 13b ^ 14 ^ 15 ^ 16 ^ 17a · 17b ^ 18 ^ 19 ^ 20a · 20b ^ 21 ^ 22a · 22b ^ 23 ^ 24 ^ 25a · 25b · 25c ^ 26 ^ 27a · 27b · 27c · 27d
    SP1:                                                                    -                       -                                             
    SP2:                                                  -                                                                                       
    SP3:                                                                                            -                                             
    SP4:                                                                                                                                          
    SP5:                                                                                                                                          


    ECgene alternative splicing isoforms for OGDHL

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    OGDHL expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CTTCAGAGAG
    OGDHL Expression
    About this image

    OGDHL expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table

    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Human kidney epithelial cell spheroids (Kidney spheroids for...)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See OGDHL Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for OGDHL

    SOURCE GeneReport for Unigene cluster: Hs.17860
        SABiosciences Expression via Pathway-Focused PCR Arrays including OGDHL: 
              Amino Acid Metabolism II in human mouse rat
              Amino Acid Metabolism I in human mouse rat
              Molecular Toxicology PathwayFinder 384HT in human mouse rat
              Glucose Metabolism in human mouse rat

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the last universal common ancestor (LUCA).

    Orthologs for OGDHL gene from 9/32 species (see all 32)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ogdhl1 , 5 oxoglutarate dehydrogenase-like1, 5 87.62(n)1
    93.17(a)1
      14 (19.40 cM)5
    2390171  NM_001081130.11  NP_001074599.11 
     323220195 
    chicken
    (Gallus gallus)
    Aves OGDHL1 oxoglutarate dehydrogenase-like 74.54(n)
    86.51(a)
      423618  NM_001199544.1  NP_001186473.1 
    lizard
    (Anolis carolinensis)
    Reptilia OGDHL6
    --
    83(a)
    1 ↔ 1
    GL343199.1(3628323-3680445)
    zebrafish
    (Danio rerio)
    Actinopterygii ogdhl1 oxoglutarate dehydrogenase-like 73.12(n)
    81.15(a)
      559207  XM_682523.3  XP_687615.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta Nc73EF6
    CG337916
    --
    56(a)
    41(a)
    many → 1
    possible ortholog
    3L(16948035-16961824)
    3L(1602954-1617355)
    worm
    (Caenorhabditis elegans)
    Secernentea ogdh-16
    2-oxoglutarate dehydrogenase, mitochondrial
    54(a)
    possible ortholog
    IV(4696827-4704005)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT3G554106
    AT5G657506
    2-oxoglutarate dehydrogenase, E1 component
    47(a)
    46(a)
    many ↔ many
    many ↔ many
    3(20541435-20546034)
    5(26303693-26308189)
    rice
    (Oryza sativa)
    Liliopsida Os.139262 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 74.5(n)    AK100482.1 
    E. coli
    (Escherichia coli)
    Gamma proteobacteria sucA6
    2-oxoglutarate decarboxylase, thiamin-requiring
    41(a)
    1 → many
    Chromosome(757929-760730)


    ENSEMBL Gene Tree for OGDHL (if available)
    TreeFam Gene Tree for OGDHL (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for OGDHL gene
    DHTKD12  OGDH2  
    2 SIMAP similar genes for OGDHL using alignment to 1 protein entry:     OGDHL_HUMAN:
    OGDH    DHTKD1

    OGDHL for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/666 NCBI SNPs in OGDHL are shown (see all 666    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs113626511,2
    C--45232274(+) AAGAG-/CCCTCT 1 -- int11Minor allele frequency- C:0.00NA 2
    rs1114017681,2
    --50942206(+) CAGTAC/TCTCCA 3 -- int11Minor allele frequency- T:0.50CSA 2
    rs12582551,2
    C,F,A,H--50942289(+) TGGCGC/TAGTGG 3 -- int110Minor allele frequency- T:0.47NA WA CSA EA 373
    rs19858961,2
    C,F--50942419(+) TAGCCA/GGGCAT 3 -- int13Minor allele frequency- G:0.33NA 6
    rs1885749121,2
    --50942457(+) CTCAGA/GAGGCT 3 -- int10--------
    rs1394469191,2
    --50942493(+) GGAGGC/TGGAGG 3 -- int10--------
    rs1916523531,2
    --50942494(+) GAGGCA/GGAGGT 3 -- int10--------
    rs751002291,2
    F--50942558(+) ACTCCG/ATCTCA 3 -- int11Minor allele frequency- A:0.05NA 120
    rs1146595961,2
    --50942605(+) CATTTT/GTTTAA 3 -- int11Minor allele frequency- G:0.01WA 118
    rs68161,2
    C,F,O,A,H--50942763(+) TTTCAC/TACAGA 3 -- ut31 ese331Minor allele frequency- T:0.44MN EA NA NS WA 3258

    HapMap Linkage Disequilibrium report for OGDHL (50942687 - 50970425 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for OGDHL
         1 Indel: 100943

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    DNA2.0 Custom Variant and Variant Library Synthesis for OGDHL

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    OGDHL for disorders           About GeneDecksing

    5 diseases for OGDHL:    About MalaCards
    kidney disease    alzheimer's disease    tuberculosis    malaria
    mycobacterium tuberculosis

    Human Genome Epidemiology (HuGE) Navigator: OGDHL (5 documents)

    Export disorders for OGDHL gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for OGDHL gene, integrated from 9 sources (see all 16):
    (articles sorted by number of sources associating them with OGDHL)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10574462)1, 2, 3 Nagase T.... Ohara O. (1999)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. Structure-function relationships in the 2-oxo acid dehydrogenase family: substrate-specific signatures and functional predictions for the 2-oxoglutarate dehydrogenase-like proteins. (PubMed id 18004749)1, 9 Bunik V.I. and Degtyarev D. (2008)
    4. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    5. Assessment of a polymorphism of SDK1 with hypertensio n in Japanese Individuals. (PubMed id 19851296)1 Oguri M....Yamada Y. (2010)
    6. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1 Hendrickson S.L....O'Brien S.J. (2010)
    7. Association of genetic variants with hemorrhagic stro ke in Japanese individuals. (PubMed id 20198315)1 Yoshida T....Yamada Y. (2010)
    8. Association of gene polymorphisms with chronic kidney disease in Japanese individuals. (PubMed id 19724895)1 Yoshida T....Yamada Y. (2009)
    9. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1 Grupe A....Goate A. (2006)
    10. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55753 HGNC: 25590 AceView: OGDHL Ensembl:ENSG00000197444 euGenes: HUgn55753
    ECgene: OGDHL Kegg: 55753 H-InvDB: OGDHL

    (According to HUGE)
    About This Section
    HUGE: KIAA1290

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for OGDHL Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for OGDHL gene:
    Search GeneIP for patents involving OGDHL

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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