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Aliases for OFC1 Gene

Aliases for OFC1 Gene

  • Orofacial Cleft 1 2 3
  • Orofacial Cleft-1 (Cleft Lip With Or Without Cleft Palate; Isolated Cleft Palate) 3
  • OFC 3
  • CL 3

External Ids for OFC1 Gene

Previous HGNC Symbols for OFC1 Gene

  • OFC

Summaries for OFC1 Gene

GeneCards Summary for OFC1 Gene

OFC1 (Orofacial Cleft 1) is a Genetic Locus. Diseases associated with OFC1 include otofaciocervical syndrome and branchiootorenal syndrome 1, with or without cataracts.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OFC1 Gene

Genomics for OFC1 Gene

Genomic Location for OFC1 Gene

Chromosome:
6
Orientation:
Unknown strand

Genomic View for OFC1 Gene


Cytogenetic band:
GeneLoc Logo Gene Density

No data available for Regulatory Elements and RefSeq DNA sequence for OFC1 Gene

Proteins for OFC1 Gene

Post-translational modifications for OFC1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for OFC1 Gene

Domains & Families for OFC1 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for OFC1 Gene

Function for OFC1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OFC1 Gene

Localization for OFC1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for OFC1 Gene

Pathways & Interactions for OFC1 Gene

SuperPathways for OFC1 Gene

No Data Available

Interacting Proteins for OFC1 Gene

Gene Ontology (GO) - Biological Process for OFC1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for OFC1 Gene

Drugs & Compounds for OFC1 Gene

No Compound Related Data Available

Expression for OFC1 Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for OFC1 Gene

Orthologs for OFC1 Gene

No data available for Orthologs and Evolution for OFC1 Gene

Paralogs for OFC1 Gene

No data available for Paralogs for OFC1 Gene

Variants for OFC1 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for OFC1 Gene

Disorders for OFC1 Gene

MalaCards: The human disease database

(5) MalaCards diseases for OFC1 Gene - From: OMIM and GeneCards

Disorder Aliases PubMed IDs
otofaciocervical syndrome
  • fara chlupackova syndrome
branchiootorenal syndrome 1, with or without cataracts
  • anterior segment anomalies with or without cataract
branchiootic syndrome 1
  • anterior segment anomalies with or without cataract
orofacial cleft
cleft lip
  • cheiloschisis
- elite association - COSMIC cancer census association via MalaCards
Search OFC1 in MalaCards View complete list of genes associated with diseases

Relevant External Links for OFC1

Genetic Association Database (GAD)
OFC1
Human Genome Epidemiology (HuGE) Navigator
OFC1
genes like me logo Genes that share disorders with OFC1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for OFC1 Gene

Publications for OFC1 Gene

  1. Contribution of 6p24 to non-syndromic cleft lip and palate in a Malay population: association of variants in OFC1. (PMID: 21297019) Salahshourifar I. … Zilfalil B.A. (J. Dent. Res. 2011) 3 48 67
  2. Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci. (PMID: 22863734) Ludwig K.U. … NAPthen M.M. (Nat. Genet. 2012) 3
  3. A locus in 2p13-p14 (OFC2), in addition to that mapped in 6p23, is involved in nonsyndromic familial orofacial cleft malformation. (PMID: 9676424) Pezzetti F. … Tognon M. (Genomics 1998) 23

Products for OFC1 Gene

Sources for OFC1 Gene

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