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Aliases & Descriptions for ODZ1
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase) About This Section
|
| Aliases |
|---|
| ODZ3 2 | | OTTHUMP00000024333 2 | | OTTHUMP00000062724 2 | | TEN-M1 1, 2 | | TNM 2 | | TNM1 2, 3 | | Ten-1 3 | | Ten-m1 3 | | Tenascin-M1 3 | | teneurin-1 2 |
| | | Descriptions |
|---|
| Protein Odd Oz/ten-m homolog 1 3 | | odz (odd Oz/ten-m, Drosophila) homolog 1 2 | | odz (odd Oz/ten-m, Drosophila) homolog 3 2 | | odz, odd Oz/ten-m homolog 1 2 | | odz, odd Oz/ten-m homolog 1(Drosophila) 2 | | tenascin M 1, 2 |
|
| | Search outside databases for aliases for ODZ1 genePrevious GC identifers: GC0XM118232 GC0XM120407 GC0XM121466 GC0XM122212 GC0XM123239 |
Summaries for ODZ1(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: TEN1_HUMAN, Q9UKZ4Function: May function as a cellular signal transducerGene Wiki entry for ODZ1 |
Genomic Location for ODZ1
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences) About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Transcription factor binding sites upstream to the ODZ1 gene 
Entrez Gene cytogenetic band: Xq25 Ensembl cytogenetic band: Xq25 HGNC cytogenetic band: Xq25ODZ1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)
 GeneLoc gene densities for chromosome X GeneLoc Exon Structure GeneLoc location for GC0XM123339:
(about GC identifiers)
Start:
|
123,339,504 bp from pter |
End:
|
123,925,347 bp from pter |
Size:
|
585,844 bases |
Orientation:
|
minus strand |
RefSeq DNA sequence:- NC_000023.9 NT_011786.15
| Proteins for ODZ1
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: TEN1_HUMAN, Q9UKZ4 (See
protein sequence)Recommended Name: Teneurin-1 Size: 2725 amino acids; 305011 Da
Subunit: Homodimer; disulfide-linked (By similarity)
Subcellular location: Membrane; Single-pass type II membrane protein (Probable)
Secondary accessions: Q5JZ17Post-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins: NP_055068.2
ENSEMBL proteins: ENSP00000360171
Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 
3 Gene Ontology (GO) cellular component terms (links to tree view): About this table
Antibodies for ODZ1: Assays for ODZ1: | Protein
Domains/ Families for ODZ1(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry Q9UKZ4
ProtoNet protein and cluster: Q9UKZ4 UniProtKB/Swiss-Prot: TEN1_HUMAN, Q9UKZ4Domain: EGF-like domains 2 and 5 which have an odd number of cysteines might enable the formation of intermolecular disulfide bondsDomain: Cytoplasmic proline-rich regions could serve as docking domains for intracellular SH3-containing proteinsSimilarity: Belongs to the tenascin family. Teneurin subfamilySimilarity: Contains 8 EGF-like domainsSimilarity: Contains 5 NHL repeatsSimilarity: Contains 1 teneurin N-terminal domainSimilarity: Contains 23 YD repeats | Gene Function for ODZ1
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_014253
Applied Biosystems Silencer® siRNAs for ODZ1
Sigma-Aldrich siRNA and siRNA Panels for ODZ1  Sigma-Aldrich shRNA for ODZ1  Explore Sigma-Aldrich super-pooled esiRNAs 
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_014253                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_014253                                  untagged cDNA clone in CMV expression vector: NM_014253 
Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_014253
UniProtKB/Swiss-Prot: TEN1_HUMAN, Q9UKZ4Function: May function as a cellular signal transducer1 Gene Ontology (GO) molecular function term (links to tree view): About this table | Pathways & Interactions for ODZ1
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
Gene Network CentralTM Interacting Genes and Proteins Network for ODZ1 
--4 Gene Ontology (GO) biological process terms (links to tree view): About this table
|
Drugs & Compounds for ODZ1(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
Browse Tocris compounds for ODZ1
|
Transcripts for ODZ1(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene, Expression Assays from Applied Biosystems) About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_014253
Sigma-Aldrich siRNA and siRNA Panels for ODZ1  Sigma-Aldrich shRNA for ODZ1  Explore Sigma-Aldrich super-pooled esiRNAs 
Applied Biosystems Silencer® siRNAs: NM_014253 REFSEQ mRNAs for ODZ1 gene: NM_014253.2
Applied Biosystems TaqMan ® Gene Expression Assays: NM_014253               OriGene GFP tagged cDNA clone in CMV expression vector: NM_014253                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_014253                                  untagged cDNA clone in CMV expression vector: NM_014253  Additional cDNA sequence: AF100772.1 BC140783.1 BC144542.1 BC144543.1 4 DOTS entries: DT.91785063 DT.100847364 DT.95174592 DT.95106234 24/48 AceView cDNA sequences (see all 48
):AI016320 BX506934 BX478232 AI498402 AL602335 AA235370 AA323193 AA331486 AW779760 AK055765 NM_014253 BX457474 AW296554 BI918168 CF454574 BX470621 BE168542 AF100772 BX494675 AL039060 BC030766 BG699146 BX108936 BX951531
highest scoring ESTs for ODZ1:AF100772 AL039060 AV708814 AW863569 BE088769 BE161640 BE161779 BE168542 BE700315 BX470621 Unigene Clusters for ODZ1: Odz, odd Oz/ten-m homolog 1(Drosophila) Hs.23796 [show with all ESTs], Hs.716649 [show with all ESTs]Unigene Representative Sequences: AK055765, NM_014253
GeneLoc Exon Structure
1 Ensembl transcript including schematic representation: ENST00000371130
|
Expression for ODZ1
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| ODZ1 expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for ODZ1
1 / 2 / 3 1 probe-set matching ODZ1 gene Data from
(Publications) and GNF BioGPS About these images About these images
CGAP SAGE TAG: AGGAACTCAT
SOURCE GeneReport for Unigene clusters: Hs.23796 Hs.716649 UniProtKB/Swiss-Prot: TEN1_HUMAN, Q9UKZ4Tissue specificity: Expressed in fetal brain |
Orthologs for ODZ1
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for ODZ1 gene from 5 species
| Organism |
Gene |
Locus |
Description |
Human Similarity |
NCBI accessions |
dog (Canis familiaris) |
ODZ11 |
-- |
odz, odd Oz/ten-m homolog 1(Drosophila) |
93.99(n) 98.42(a) |
612901 XM_860042.1 XP_865135.1 |
mouse (Mus musculus) |
Odz11, 5 |
X5
|
odd Oz/ten-m homolog 1 (Drosophila)1, 5 |
91.31(n)1 96.99(a)1 |
239631 NM_011855.31 NP_035985.21 AB0254105 AK0378975 (see all 11) |
chicken (Gallus gallus) |
ODZ11 |
-- |
odz, odd Oz/ten-m homolog 1(Drosophila) |
80.17(n) 89.88(a) |
395668 NM_204862.1 NP_990193.1 |
zebrafish (Danio rerio) |
CH211-1C4.11 |
-- |
novel protein similar to vertebrate odz, odd Oz/ten-m more |
64.57(n) 67.17(a) |
563094 XM_686460.3 XP_691552.3 |
fruit fly (Drosophila melanogaster) |
Ten-a3 |
11A7--8 |
cell adhesion cell adhesion molecule |
43(a) (best of 2) |
-- |
About this table Species with no ortholog for ODZ1
ENSEMBL Gene Tree for ODZ1 | Paralogs for ODZ1(Paralogs according to 1HomoloGene and 2Ensembl, Pseudogenes according to 3Pseudogene.org) About This Section
| Paralogs for ODZ1 gene
- ODZ32 ODZ42 ODZ22
|
SNPs/Variants for ODZ1(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for ODZ1 (up to first 250kb)
|
Disorders & Mutations for ODZ1
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
|
OMIM: 300588
|
Medical News for ODZ1(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications for ODZ1 (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 10/15 PubMed articles for ODZ1 gene (see all 15
):- Teneurin-1, a vertebrate homologue of the Drosophila pair-rule gene ten-m, is a neuronal protein with a novel type of heparin-binding domain. (PubMed id 10341219)1, 2, 3, 4 Minet A.D....Chiquet-Ehrismann R. (1999)
- The DNA sequence of the human X chromosome. (PubMed id 15772651)3, 4 Ross M.T.... Bentley D.R. (2005)
- Mapping homologs of Drosophila odd Oz (odz): Doc4/Odz4 to mouse chromosome 7, Odz1 to mouse chromosome 11; and ODZ3 to human chromosome Xq25. (PubMed id 10331952)2, 3 Ben-Zur T. and Wides R. (1999)
- Epstein-Barr virus-negative boys with non-Hodgkin lymphoma are mutated in the SH2D1A gene, as are patients with X-linked lymphoproliferative disease (XLP). (PubMed id 10556288)3, 4 Brandau O....Meindl A. (1999)
- The intracellular domain of teneurin-1 interacts with MBD1 and CAP/ponsin resulting in subcellular codistribution and translocation to the nuclear matrix. (PubMed id 15777793)1, 3 Nunes S.M....Chiquet-Ehrismann R. (2005)
- A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)4 Dephoure N.... Gygi S.P. (2008)
- The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)4 Sjoeblom T.... Velculescu V.E. (2006)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)3 Kimura K.... Sugano S. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)3 Ota T....Sugano S. (2004)
- Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PubMed id 15146197)3 Brandenberger R.... Stanton L.W. (2004)
|
Search for ODZ1
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing ODZ1
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing ODZ1
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ODZ1(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| About This Section
| --
| Services for ODZ1(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals, Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience) About This Section
| 
 Products for ODZ1:

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